CA2852198A1 - Aerosol propellants comprising unsaturated fluorocarbons - Google Patents
Aerosol propellants comprising unsaturated fluorocarbons Download PDFInfo
- Publication number
- CA2852198A1 CA2852198A1 CA2852198A CA2852198A CA2852198A1 CA 2852198 A1 CA2852198 A1 CA 2852198A1 CA 2852198 A CA2852198 A CA 2852198A CA 2852198 A CA2852198 A CA 2852198A CA 2852198 A1 CA2852198 A1 CA 2852198A1
- Authority
- CA
- Canada
- Prior art keywords
- cf3ch
- chf
- cf3cf
- chcf
- chc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 239000003380 propellant Substances 0.000 title claims abstract description 46
- 239000000203 mixture Substances 0.000 claims abstract description 70
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims description 68
- 239000000443 aerosol Substances 0.000 claims description 29
- SNVLJLYUUXKWOJ-UHFFFAOYSA-N methylidenecarbene Chemical compound C=[C] SNVLJLYUUXKWOJ-UHFFFAOYSA-N 0.000 claims description 19
- 125000000219 ethylidene group Chemical group [H]C(=[*])C([H])([H])[H] 0.000 claims description 17
- 125000005004 perfluoroethyl group Chemical group FC(F)(F)C(F)(F)* 0.000 claims description 12
- GVNVAWHJIKLAGL-UHFFFAOYSA-N 2-(cyclohexen-1-yl)cyclohexan-1-one Chemical compound O=C1CCCCC1C1=CCCCC1 GVNVAWHJIKLAGL-UHFFFAOYSA-N 0.000 claims description 11
- 101150065749 Churc1 gene Proteins 0.000 claims description 11
- 102100038239 Protein Churchill Human genes 0.000 claims description 11
- 239000007921 spray Substances 0.000 claims description 11
- JNCMHMUGTWEVOZ-UHFFFAOYSA-N F[CH]F Chemical compound F[CH]F JNCMHMUGTWEVOZ-UHFFFAOYSA-N 0.000 claims description 9
- 108010081348 HRT1 protein Hairy Proteins 0.000 claims description 9
- 102100021881 Hairy/enhancer-of-split related with YRPW motif protein 1 Human genes 0.000 claims description 9
- 125000006340 pentafluoro ethyl group Chemical group FC(F)(F)C(F)(F)* 0.000 claims description 8
- 239000003814 drug Substances 0.000 claims description 7
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 claims description 7
- 125000004206 2,2,2-trifluoroethyl group Chemical group [H]C([H])(*)C(F)(F)F 0.000 claims description 6
- GYOLCDNHOFVAAM-UHFFFAOYSA-N bromo(difluoro)methane Chemical compound F[C](F)Br GYOLCDNHOFVAAM-UHFFFAOYSA-N 0.000 claims description 5
- 239000008266 hair spray Substances 0.000 claims description 4
- 239000002304 perfume Substances 0.000 claims description 3
- QAERDLQYXMEHEB-UHFFFAOYSA-N 1,1,3,3,3-pentafluoroprop-1-ene Chemical compound FC(F)=CC(F)(F)F QAERDLQYXMEHEB-UHFFFAOYSA-N 0.000 claims description 2
- 229940125388 beta agonist Drugs 0.000 claims description 2
- AOJDZKCUAATBGE-UHFFFAOYSA-N bromomethane Chemical compound Br[CH2] AOJDZKCUAATBGE-UHFFFAOYSA-N 0.000 claims description 2
- 239000003246 corticosteroid Substances 0.000 claims description 2
- 239000002781 deodorant agent Substances 0.000 claims description 2
- 125000006342 heptafluoro i-propyl group Chemical group FC(F)(F)C(F)(*)C(F)(F)F 0.000 claims description 2
- 125000006341 heptafluoro n-propyl group Chemical group FC(F)(F)C(F)(F)C(F)(F)* 0.000 claims description 2
- 239000002917 insecticide Substances 0.000 claims description 2
- 125000006344 nonafluoro n-butyl group Chemical group FC(F)(F)C(F)(F)C(F)(F)C(F)(F)* 0.000 claims description 2
- 125000006663 (C1-C6) perfluoroalkyl group Chemical group 0.000 claims 1
- IZHPSCJEIFFRLN-UHFFFAOYSA-N 3,3,4,4,4-pentafluorobut-1-ene Chemical compound FC(F)(F)C(F)(F)C=C IZHPSCJEIFFRLN-UHFFFAOYSA-N 0.000 claims 1
- 229940071648 metered dose inhaler Drugs 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 description 22
- 239000000047 product Substances 0.000 description 17
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 15
- -1 CH2FCF=CFCF3 Chemical compound 0.000 description 14
- 238000006243 chemical reaction Methods 0.000 description 14
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 13
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 12
- 238000000034 method Methods 0.000 description 12
- 239000000126 substance Substances 0.000 description 12
- 238000005914 dehydroiodination reaction Methods 0.000 description 11
- 239000007789 gas Substances 0.000 description 9
- 239000002904 solvent Substances 0.000 description 9
- 239000000376 reactant Substances 0.000 description 8
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 238000009472 formulation Methods 0.000 description 6
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 6
- 239000012855 volatile organic compound Substances 0.000 description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 5
- 239000004480 active ingredient Substances 0.000 description 5
- 238000010792 warming Methods 0.000 description 5
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 4
- QQONPFPTGQHPMA-UHFFFAOYSA-N Propene Chemical compound CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 4
- 229930195733 hydrocarbon Natural products 0.000 description 4
- 150000002430 hydrocarbons Chemical class 0.000 description 4
- 238000012544 monitoring process Methods 0.000 description 4
- 239000012071 phase Substances 0.000 description 4
- 238000011160 research Methods 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
- 230000001166 anti-perspirative effect Effects 0.000 description 3
- 239000003213 antiperspirant Substances 0.000 description 3
- JFDZBHWFFUWGJE-UHFFFAOYSA-N benzonitrile Chemical compound N#CC1=CC=CC=C1 JFDZBHWFFUWGJE-UHFFFAOYSA-N 0.000 description 3
- 239000001569 carbon dioxide Substances 0.000 description 3
- 229910002092 carbon dioxide Inorganic materials 0.000 description 3
- 230000007613 environmental effect Effects 0.000 description 3
- 239000003205 fragrance Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 3
- ZQDPJFUHLCOCRG-AATRIKPKSA-N trans-3-hexene Chemical compound CC\C=C\CC ZQDPJFUHLCOCRG-AATRIKPKSA-N 0.000 description 3
- LIKMAJRDDDTEIG-UHFFFAOYSA-N 1-hexene Chemical compound CCCCC=C LIKMAJRDDDTEIG-UHFFFAOYSA-N 0.000 description 2
- OHMHBGPWCHTMQE-UHFFFAOYSA-N 2,2-dichloro-1,1,1-trifluoroethane Chemical compound FC(F)(F)C(Cl)Cl OHMHBGPWCHTMQE-UHFFFAOYSA-N 0.000 description 2
- FXRLMCRCYDHQFW-UHFFFAOYSA-N 2,3,3,3-tetrafluoropropene Chemical compound FC(=C)C(F)(F)F FXRLMCRCYDHQFW-UHFFFAOYSA-N 0.000 description 2
- YAPVBRYHZPNRIW-UHFFFAOYSA-N 4-bromo-1,1,1,2,2-pentafluorobutane Chemical compound FC(F)(F)C(F)(F)CCBr YAPVBRYHZPNRIW-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 239000004604 Blowing Agent Substances 0.000 description 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 description 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- BZLVMXJERCGZMT-UHFFFAOYSA-N Methyl tert-butyl ether Chemical compound COC(C)(C)C BZLVMXJERCGZMT-UHFFFAOYSA-N 0.000 description 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
- IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 description 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- GQPLMRYTRLFLPF-UHFFFAOYSA-N Nitrous Oxide Chemical compound [O-][N+]#N GQPLMRYTRLFLPF-UHFFFAOYSA-N 0.000 description 2
- WQDUMFSSJAZKTM-UHFFFAOYSA-N Sodium methoxide Chemical compound [Na+].[O-]C WQDUMFSSJAZKTM-UHFFFAOYSA-N 0.000 description 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 2
- 238000013019 agitation Methods 0.000 description 2
- 239000002386 air freshener Substances 0.000 description 2
- 239000012298 atmosphere Substances 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 2
- 229910052794 bromium Inorganic materials 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 125000001309 chloro group Chemical group Cl* 0.000 description 2
- OTTZHAVKAVGASB-UHFFFAOYSA-N hept-2-ene Chemical compound CCCCC=CC OTTZHAVKAVGASB-UHFFFAOYSA-N 0.000 description 2
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 125000005010 perfluoroalkyl group Chemical group 0.000 description 2
- 239000003444 phase transfer catalyst Substances 0.000 description 2
- VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 description 2
- NIJFGUAYRFPTBD-OWOJBTEDSA-N (e)-1,1,1,2,2,3,3,6,6,7,7,8,8,8-tetradecafluorooct-4-ene Chemical compound FC(F)(F)C(F)(F)C(F)(F)\C=C\C(F)(F)C(F)(F)C(F)(F)F NIJFGUAYRFPTBD-OWOJBTEDSA-N 0.000 description 1
- UGHJWZHBCXGSAY-OWOJBTEDSA-N (e)-1,1,1,2,3,4,4,5,5,6,6,7,7,7-tetradecafluorohept-2-ene Chemical compound FC(F)(F)C(/F)=C(\F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F UGHJWZHBCXGSAY-OWOJBTEDSA-N 0.000 description 1
- SAPOZTRFWJZUFT-OWOJBTEDSA-N (e)-1,1,1,2,3,4,5,5,5-nonafluoro-4-(trifluoromethyl)pent-2-ene Chemical compound FC(F)(F)C(/F)=C(\F)C(F)(C(F)(F)F)C(F)(F)F SAPOZTRFWJZUFT-OWOJBTEDSA-N 0.000 description 1
- MZPZBRBIEBBNIA-UPHRSURJSA-N (z)-1,1,1,3,4,4,5,5,5-nonafluoropent-2-ene Chemical compound FC(F)(F)\C=C(/F)C(F)(F)C(F)(F)F MZPZBRBIEBBNIA-UPHRSURJSA-N 0.000 description 1
- DDKFHEFCVPCJKU-UPHRSURJSA-N (z)-1,1,2,4,4-pentafluorobut-2-ene Chemical compound FC(F)\C=C(/F)C(F)F DDKFHEFCVPCJKU-UPHRSURJSA-N 0.000 description 1
- RRUCZSCEAWFDBM-UPHRSURJSA-N (z)-1-bromo-2,3,3,3-tetrafluoroprop-1-ene Chemical compound Br\C=C(/F)C(F)(F)F RRUCZSCEAWFDBM-UPHRSURJSA-N 0.000 description 1
- GJAJMLHFWTWPES-UPHRSURJSA-N (z)-2-bromo-1,3,3,3-tetrafluoroprop-1-ene Chemical compound F\C=C(/Br)C(F)(F)F GJAJMLHFWTWPES-UPHRSURJSA-N 0.000 description 1
- RFYFRYQYXJPKMF-UHFFFAOYSA-N 1,1,1,2,2,3,4,5,5,6,6,6-dodecafluorohex-3-ene Chemical compound FC(F)(F)C(F)(F)C(F)=C(F)C(F)(F)C(F)(F)F RFYFRYQYXJPKMF-UHFFFAOYSA-N 0.000 description 1
- YWSYXYXSEWRSMA-UHFFFAOYSA-N 1,1,1,2,2,5,5,6,6,7,7,7-dodecafluorohept-3-ene Chemical compound FC(F)(F)C(F)(F)C=CC(F)(F)C(F)(F)C(F)(F)F YWSYXYXSEWRSMA-UHFFFAOYSA-N 0.000 description 1
- IKEULTDRFFGVIG-UHFFFAOYSA-N 1,1,1,2,2,5,5,6,6,7,7,8,8,9,9,9-hexadecafluoronon-3-ene Chemical compound FC(F)(F)C(F)(F)C=CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F IKEULTDRFFGVIG-UHFFFAOYSA-N 0.000 description 1
- YFIWYJWEYMDJFB-UHFFFAOYSA-N 1,1,1,2,2,5,5,6,7,7,7-undecafluoro-6-(trifluoromethyl)hept-3-ene Chemical compound FC(F)(F)C(F)(F)C=CC(F)(F)C(F)(C(F)(F)F)C(F)(F)F YFIWYJWEYMDJFB-UHFFFAOYSA-N 0.000 description 1
- UGHJWZHBCXGSAY-UHFFFAOYSA-N 1,1,1,2,3,4,4,5,5,6,6,7,7,7-tetradecafluorohept-2-ene Chemical compound FC(F)(F)C(F)=C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F UGHJWZHBCXGSAY-UHFFFAOYSA-N 0.000 description 1
- JSADPKAWAKXUTE-UHFFFAOYSA-N 1,1,1,2,3,4-hexafluorobut-2-ene Chemical compound FCC(F)=C(F)C(F)(F)F JSADPKAWAKXUTE-UHFFFAOYSA-N 0.000 description 1
- HBNXKNOVGAHUNV-UHFFFAOYSA-N 1,1,1,2,3-pentafluorobut-2-ene Chemical compound CC(F)=C(F)C(F)(F)F HBNXKNOVGAHUNV-UHFFFAOYSA-N 0.000 description 1
- JZSOMBFGZXZIJI-UHFFFAOYSA-N 1,1,1,2,4-pentafluorobut-2-ene Chemical compound FCC=C(F)C(F)(F)F JZSOMBFGZXZIJI-UHFFFAOYSA-N 0.000 description 1
- JVLWJKWBKARHRQ-UHFFFAOYSA-N 1,1,1,3,4,4-hexafluorobut-2-ene Chemical compound FC(F)C(F)=CC(F)(F)F JVLWJKWBKARHRQ-UHFFFAOYSA-N 0.000 description 1
- CUKJWRYRLCTJNJ-UHFFFAOYSA-N 1,1,1,4,4,4-hexafluoro-2,3-bis(trifluoromethyl)but-2-ene Chemical compound FC(F)(F)C(C(F)(F)F)=C(C(F)(F)F)C(F)(F)F CUKJWRYRLCTJNJ-UHFFFAOYSA-N 0.000 description 1
- ZBKIRWGFFLBFDX-UHFFFAOYSA-N 1,1,1,4,4,4-hexafluoro-2-(trifluoromethyl)but-2-ene Chemical compound FC(F)(F)C=C(C(F)(F)F)C(F)(F)F ZBKIRWGFFLBFDX-UHFFFAOYSA-N 0.000 description 1
- NLOLSXYRJFEOTA-UHFFFAOYSA-N 1,1,1,4,4,4-hexafluorobut-2-ene Chemical compound FC(F)(F)C=CC(F)(F)F NLOLSXYRJFEOTA-UHFFFAOYSA-N 0.000 description 1
- BRHMFXVXLONVKC-UHFFFAOYSA-N 1,1,1,4,4,5,5,6,6,6-decafluorohex-2-ene Chemical compound FC(F)(F)C=CC(F)(F)C(F)(F)C(F)(F)F BRHMFXVXLONVKC-UHFFFAOYSA-N 0.000 description 1
- FQJHHXBFDDKSEP-UHFFFAOYSA-N 1,1,1,4-tetrafluoro-2-(trifluoromethyl)but-2-ene Chemical compound FCC=C(C(F)(F)F)C(F)(F)F FQJHHXBFDDKSEP-UHFFFAOYSA-N 0.000 description 1
- ZLHAZCCTGKVALM-UHFFFAOYSA-N 1,1,1-trifluorodec-5-ene Chemical compound CCCCC=CCCCC(F)(F)F ZLHAZCCTGKVALM-UHFFFAOYSA-N 0.000 description 1
- YLJDUZGXRKGBJW-UHFFFAOYSA-N 1,1,1-trifluorohex-3-ene Chemical compound CCC=CCC(F)(F)F YLJDUZGXRKGBJW-UHFFFAOYSA-N 0.000 description 1
- RMHCWMIZBMGHKV-UHFFFAOYSA-N 1,1,2,3,3,4,4,5,5,6,6,6-dodecafluorohex-1-ene Chemical compound FC(F)=C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F RMHCWMIZBMGHKV-UHFFFAOYSA-N 0.000 description 1
- CCHWGPNQONFKSV-UHFFFAOYSA-N 1,1,2,3,4,4,5,5,5-nonafluoropent-2-ene Chemical compound FC(F)C(F)=C(F)C(F)(F)C(F)(F)F CCHWGPNQONFKSV-UHFFFAOYSA-N 0.000 description 1
- PGJHURKAWUJHLJ-UHFFFAOYSA-N 1,1,2,3-tetrafluoroprop-1-ene Chemical compound FCC(F)=C(F)F PGJHURKAWUJHLJ-UHFFFAOYSA-N 0.000 description 1
- LNGDLROYEAUMEQ-UHFFFAOYSA-N 1,1,2-trifluoroprop-1-ene Chemical compound CC(F)=C(F)F LNGDLROYEAUMEQ-UHFFFAOYSA-N 0.000 description 1
- WEYCUBLCUXRXRQ-UHFFFAOYSA-N 1,1,3,3,3-pentafluoro-2-methylprop-1-ene Chemical compound FC(F)=C(C)C(F)(F)F WEYCUBLCUXRXRQ-UHFFFAOYSA-N 0.000 description 1
- DMUPYMORYHFFCT-UHFFFAOYSA-N 1,2,3,3,3-pentafluoroprop-1-ene Chemical compound FC=C(F)C(F)(F)F DMUPYMORYHFFCT-UHFFFAOYSA-N 0.000 description 1
- PVYYRPAHXQUHAW-UHFFFAOYSA-N 1,2,3,3,4,4,4-heptafluorobut-1-ene Chemical compound FC=C(F)C(F)(F)C(F)(F)F PVYYRPAHXQUHAW-UHFFFAOYSA-N 0.000 description 1
- ZFFLXJVVPHACEG-UHFFFAOYSA-N 1,2,3,3,4,4,5,5,6,6-decafluorocyclohexene Chemical compound FC1=C(F)C(F)(F)C(F)(F)C(F)(F)C1(F)F ZFFLXJVVPHACEG-UHFFFAOYSA-N 0.000 description 1
- TXHNVFGQJAAUNB-UHFFFAOYSA-N 1,2,3-trifluoroprop-1-ene Chemical compound FCC(F)=CF TXHNVFGQJAAUNB-UHFFFAOYSA-N 0.000 description 1
- WSLDOOZREJYCGB-UHFFFAOYSA-N 1,2-Dichloroethane Chemical compound ClCCCl WSLDOOZREJYCGB-UHFFFAOYSA-N 0.000 description 1
- FYDLLXJLGCDGFH-UHFFFAOYSA-N 1,3,3,3-tetrafluoro-2-(trifluoromethyl)prop-1-ene Chemical compound FC=C(C(F)(F)F)C(F)(F)F FYDLLXJLGCDGFH-UHFFFAOYSA-N 0.000 description 1
- LYSWMVUQFULFQU-UHFFFAOYSA-N 1,3,3,4,4,4-hexafluorobut-1-ene Chemical compound FC=CC(F)(F)C(F)(F)F LYSWMVUQFULFQU-UHFFFAOYSA-N 0.000 description 1
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 1
- YPKJLUMZCXWKMY-UHFFFAOYSA-N 1-bromo-3,3,3-trifluoro-2-(trifluoromethyl)prop-1-ene Chemical compound FC(F)(F)C(=CBr)C(F)(F)F YPKJLUMZCXWKMY-UHFFFAOYSA-N 0.000 description 1
- GCAHVBRJLBKRSZ-UHFFFAOYSA-N 1-bromo-3,3,4,4,4-pentafluorobut-1-ene Chemical compound FC(F)(F)C(F)(F)C=CBr GCAHVBRJLBKRSZ-UHFFFAOYSA-N 0.000 description 1
- IUXHPSPHPKXTPA-UHFFFAOYSA-N 1-bromobut-1-ene Chemical compound CCC=CBr IUXHPSPHPKXTPA-UHFFFAOYSA-N 0.000 description 1
- VFTFKUDGYRBSAL-UHFFFAOYSA-N 15-crown-5 Chemical compound C1COCCOCCOCCOCCO1 VFTFKUDGYRBSAL-UHFFFAOYSA-N 0.000 description 1
- XEZNGIUYQVAUSS-UHFFFAOYSA-N 18-crown-6 Chemical compound C1COCCOCCOCCOCCOCCO1 XEZNGIUYQVAUSS-UHFFFAOYSA-N 0.000 description 1
- NHGSUDHIUKAWHN-UHFFFAOYSA-N 2,4,4,4-tetrafluoro-3-(trifluoromethyl)but-1-ene Chemical compound FC(=C)C(C(F)(F)F)C(F)(F)F NHGSUDHIUKAWHN-UHFFFAOYSA-N 0.000 description 1
- MLVGEIZMIFSKRK-UHFFFAOYSA-N 2-bromo-1,1,1,3,4,4,4-heptafluorobut-2-ene Chemical compound FC(F)(F)C(F)=C(Br)C(F)(F)F MLVGEIZMIFSKRK-UHFFFAOYSA-N 0.000 description 1
- UBVPDGAKNZNBQX-UHFFFAOYSA-N 2-bromo-1,1,1-trifluorobut-2-ene Chemical compound CC=C(Br)C(F)(F)F UBVPDGAKNZNBQX-UHFFFAOYSA-N 0.000 description 1
- CPBVEQZEIHBLOJ-UHFFFAOYSA-N 2-bromo-1,1,3,4,4,5,5,5-octafluoropent-1-ene Chemical compound FC(F)=C(Br)C(F)C(F)(F)C(F)(F)F CPBVEQZEIHBLOJ-UHFFFAOYSA-N 0.000 description 1
- UTRVHQFNNPVYDP-UHFFFAOYSA-N 2-bromo-1,3,3-trifluoroprop-1-ene Chemical compound FC=C(Br)C(F)F UTRVHQFNNPVYDP-UHFFFAOYSA-N 0.000 description 1
- ZWRZDAJOBBXUHV-UHFFFAOYSA-N 2-bromo-3,4,4,4-tetrafluoro-3-(trifluoromethyl)but-1-ene Chemical compound FC(F)(F)C(F)(C(Br)=C)C(F)(F)F ZWRZDAJOBBXUHV-UHFFFAOYSA-N 0.000 description 1
- ZKYCLDTVJCJYIB-UHFFFAOYSA-N 2-methylidenedecanamide Chemical compound CCCCCCCCC(=C)C(N)=O ZKYCLDTVJCJYIB-UHFFFAOYSA-N 0.000 description 1
- JWUJQDFVADABEY-UHFFFAOYSA-N 2-methyltetrahydrofuran Chemical compound CC1CCCO1 JWUJQDFVADABEY-UHFFFAOYSA-N 0.000 description 1
- FDMFUZHCIRHGRG-UHFFFAOYSA-N 3,3,3-trifluoroprop-1-ene Chemical compound FC(F)(F)C=C FDMFUZHCIRHGRG-UHFFFAOYSA-N 0.000 description 1
- JPMHUDBOKDBBLG-UHFFFAOYSA-N 3,3,4,4,4-pentafluorobutan-1-ol Chemical compound OCCC(F)(F)C(F)(F)F JPMHUDBOKDBBLG-UHFFFAOYSA-N 0.000 description 1
- GVEUEBXMTMZVSD-UHFFFAOYSA-N 3,3,4,4,5,5,6,6,6-nonafluorohex-1-ene Chemical group FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C=C GVEUEBXMTMZVSD-UHFFFAOYSA-N 0.000 description 1
- YCJCPOBHORUPPD-UHFFFAOYSA-N 3,4,4,5,5,5-hexafluoropent-2-ene Chemical compound CC=C(F)C(F)(F)C(F)(F)F YCJCPOBHORUPPD-UHFFFAOYSA-N 0.000 description 1
- LWZHLGVBJNOFFQ-UHFFFAOYSA-N 3-bromo-1,1,1-trifluorobut-2-ene Chemical compound CC(Br)=CC(F)(F)F LWZHLGVBJNOFFQ-UHFFFAOYSA-N 0.000 description 1
- FRVWTAHTVVUDFK-UHFFFAOYSA-N 3-bromo-1,1,3,3-tetrafluoroprop-1-ene Chemical compound FC(F)=CC(F)(F)Br FRVWTAHTVVUDFK-UHFFFAOYSA-N 0.000 description 1
- FOHSROKXSQGKQE-UHFFFAOYSA-N 3-bromo-1,3,3-trifluoroprop-1-ene Chemical compound FC=CC(F)(F)Br FOHSROKXSQGKQE-UHFFFAOYSA-N 0.000 description 1
- QOBDJYBYWKIIFQ-UHFFFAOYSA-N 3-bromo-2,3,3-trifluoroprop-1-ene Chemical compound FC(=C)C(F)(F)Br QOBDJYBYWKIIFQ-UHFFFAOYSA-N 0.000 description 1
- FVUGYACZNWKBNI-UHFFFAOYSA-N 4,4,4-trifluoro-3-(trifluoromethyl)but-1-ene Chemical compound FC(F)(F)C(C=C)C(F)(F)F FVUGYACZNWKBNI-UHFFFAOYSA-N 0.000 description 1
- ZSGPNFJGOLGNLM-UHFFFAOYSA-N 4,4-dibromo-1,1,1,2,2-pentafluorobutane Chemical compound FC(F)(F)C(F)(F)CC(Br)Br ZSGPNFJGOLGNLM-UHFFFAOYSA-N 0.000 description 1
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 1
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 1
- 206010006326 Breath odour Diseases 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 description 1
- 229910000881 Cu alloy Inorganic materials 0.000 description 1
- XTHFKEDIFFGKHM-UHFFFAOYSA-N Dimethoxyethane Chemical compound COCCOC XTHFKEDIFFGKHM-UHFFFAOYSA-N 0.000 description 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- 208000032139 Halitosis Diseases 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 229910000792 Monel Inorganic materials 0.000 description 1
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 description 1
- 229910000990 Ni alloy Inorganic materials 0.000 description 1
- CYTYCFOTNPOANT-UHFFFAOYSA-N Perchloroethylene Chemical group ClC(Cl)=C(Cl)Cl CYTYCFOTNPOANT-UHFFFAOYSA-N 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical compound CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 description 1
- BAPJBEWLBFYGME-UHFFFAOYSA-N acrylic acid methyl ester Natural products COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- BTGRAWJCKBQKAO-UHFFFAOYSA-N adiponitrile Chemical compound N#CCCCCC#N BTGRAWJCKBQKAO-UHFFFAOYSA-N 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 150000001335 aliphatic alkanes Chemical class 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 description 1
- 229910000272 alkali metal oxide Inorganic materials 0.000 description 1
- 229910001860 alkaline earth metal hydroxide Inorganic materials 0.000 description 1
- 229910000287 alkaline earth metal oxide Inorganic materials 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N ammonia Natural products N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 1
- 230000001088 anti-asthma Effects 0.000 description 1
- 239000000924 antiasthmatic agent Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- HTZCNXWZYVXIMZ-UHFFFAOYSA-M benzyl(triethyl)azanium;chloride Chemical compound [Cl-].CC[N+](CC)(CC)CC1=CC=CC=C1 HTZCNXWZYVXIMZ-UHFFFAOYSA-M 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 230000031709 bromination Effects 0.000 description 1
- 238000005893 bromination reaction Methods 0.000 description 1
- 239000001273 butane Substances 0.000 description 1
- KVNRLNFWIYMESJ-UHFFFAOYSA-N butyronitrile Chemical compound CCCC#N KVNRLNFWIYMESJ-UHFFFAOYSA-N 0.000 description 1
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 1
- 239000000920 calcium hydroxide Substances 0.000 description 1
- 229910001861 calcium hydroxide Inorganic materials 0.000 description 1
- BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 description 1
- 239000000292 calcium oxide Substances 0.000 description 1
- ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000000788 chromium alloy Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- YOCUPQPZWBBYIX-UHFFFAOYSA-N copper nickel Chemical compound [Ni].[Cu] YOCUPQPZWBBYIX-UHFFFAOYSA-N 0.000 description 1
- 150000003983 crown ethers Chemical class 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- LVYZJEPLMYTTGH-UHFFFAOYSA-H dialuminum chloride pentahydroxide dihydrate Chemical compound [Cl-].[Al+3].[OH-].[OH-].[Al+3].[OH-].[OH-].[OH-].O.O LVYZJEPLMYTTGH-UHFFFAOYSA-H 0.000 description 1
- SBZXBUIDTXKZTM-UHFFFAOYSA-N diglyme Chemical compound COCCOCCOC SBZXBUIDTXKZTM-UHFFFAOYSA-N 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- DDXLVDQZPFLQMZ-UHFFFAOYSA-M dodecyl(trimethyl)azanium;chloride Chemical compound [Cl-].CCCCCCCCCCCC[N+](C)(C)C DDXLVDQZPFLQMZ-UHFFFAOYSA-M 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 150000004820 halides Chemical group 0.000 description 1
- 150000008282 halocarbons Chemical class 0.000 description 1
- KWLMIXQRALPRBC-UHFFFAOYSA-L hectorite Chemical compound [Li+].[OH-].[OH-].[Na+].[Mg+2].O1[Si]2([O-])O[Si]1([O-])O[Si]([O-])(O1)O[Si]1([O-])O2 KWLMIXQRALPRBC-UHFFFAOYSA-L 0.000 description 1
- 229910000271 hectorite Inorganic materials 0.000 description 1
- WZHKDGJSXCTSCK-UHFFFAOYSA-N hept-3-ene Chemical compound CCCC=CCC WZHKDGJSXCTSCK-UHFFFAOYSA-N 0.000 description 1
- SHFJWMWCIHQNCP-UHFFFAOYSA-M hydron;tetrabutylazanium;sulfate Chemical compound OS([O-])(=O)=O.CCCC[N+](CCCC)(CCCC)CCCC SHFJWMWCIHQNCP-UHFFFAOYSA-M 0.000 description 1
- 229910001026 inconel Inorganic materials 0.000 description 1
- 229940060367 inert ingredients Drugs 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 229910000623 nickel–chromium alloy Inorganic materials 0.000 description 1
- 150000002825 nitriles Chemical class 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 239000001272 nitrous oxide Substances 0.000 description 1
- YCBSHDKATAPNIA-UHFFFAOYSA-N non-3-ene Chemical compound CCCCCC=CCC YCBSHDKATAPNIA-UHFFFAOYSA-N 0.000 description 1
- TVMXDCGIABBOFY-UHFFFAOYSA-N octane Chemical compound CCCCCCCC TVMXDCGIABBOFY-UHFFFAOYSA-N 0.000 description 1
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- HTXFNORGOSHHJJ-UHFFFAOYSA-N pent-2-ene Chemical compound CC[C]=CC HTXFNORGOSHHJJ-UHFFFAOYSA-N 0.000 description 1
- YWAKXRMUMFPDSH-UHFFFAOYSA-N pentene Chemical compound CCCC=C YWAKXRMUMFPDSH-UHFFFAOYSA-N 0.000 description 1
- QMMOXUPEWRXHJS-UHFFFAOYSA-N pentene-2 Natural products CCC=CC QMMOXUPEWRXHJS-UHFFFAOYSA-N 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 238000005191 phase separation Methods 0.000 description 1
- 125000005496 phosphonium group Chemical group 0.000 description 1
- IPNPIHIZVLFAFP-UHFFFAOYSA-N phosphorus tribromide Chemical compound BrP(Br)Br IPNPIHIZVLFAFP-UHFFFAOYSA-N 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000003495 polar organic solvent Substances 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- FVSKHRXBFJPNKK-UHFFFAOYSA-N propionitrile Chemical compound CCC#N FVSKHRXBFJPNKK-UHFFFAOYSA-N 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- ODZPKZBBUMBTMG-UHFFFAOYSA-N sodium amide Chemical compound [NH2-].[Na+] ODZPKZBBUMBTMG-UHFFFAOYSA-N 0.000 description 1
- QDRKDTQENPPHOJ-UHFFFAOYSA-N sodium ethoxide Chemical compound [Na+].CC[O-] QDRKDTQENPPHOJ-UHFFFAOYSA-N 0.000 description 1
- KKCBUQHMOMHUOY-UHFFFAOYSA-N sodium oxide Chemical compound [O-2].[Na+].[Na+] KKCBUQHMOMHUOY-UHFFFAOYSA-N 0.000 description 1
- 229910001948 sodium oxide Inorganic materials 0.000 description 1
- HUAUNKAZQWMVFY-UHFFFAOYSA-M sodium;oxocalcium;hydroxide Chemical compound [OH-].[Na+].[Ca]=O HUAUNKAZQWMVFY-UHFFFAOYSA-M 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000005437 stratosphere Substances 0.000 description 1
- HXJUTPCZVOIRIF-UHFFFAOYSA-N sulfolane Chemical compound O=S1(=O)CCCC1 HXJUTPCZVOIRIF-UHFFFAOYSA-N 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- JRMUNVKIHCOMHV-UHFFFAOYSA-M tetrabutylammonium bromide Chemical compound [Br-].CCCC[N+](CCCC)(CCCC)CCCC JRMUNVKIHCOMHV-UHFFFAOYSA-M 0.000 description 1
- ZUHZGEOKBKGPSW-UHFFFAOYSA-N tetraglyme Chemical compound COCCOCCOCCOCCOC ZUHZGEOKBKGPSW-UHFFFAOYSA-N 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- WAGFXJQAIZNSEQ-UHFFFAOYSA-M tetraphenylphosphonium chloride Chemical compound [Cl-].C1=CC=CC=C1[P+](C=1C=CC=CC=1)(C=1C=CC=CC=1)C1=CC=CC=C1 WAGFXJQAIZNSEQ-UHFFFAOYSA-M 0.000 description 1
- ADZJWYULTMTLQZ-UHFFFAOYSA-N tritylphosphane;hydrobromide Chemical compound [Br-].C=1C=CC=CC=1C(C=1C=CC=CC=1)([PH3+])C1=CC=CC=C1 ADZJWYULTMTLQZ-UHFFFAOYSA-N 0.000 description 1
- 239000005436 troposphere Substances 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K3/00—Materials not provided for elsewhere
- C09K3/30—Materials not provided for elsewhere for aerosols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/124—Aerosols; Foams characterised by the propellant
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Organic Chemistry (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73229205P | 2005-11-01 | 2005-11-01 | |
| US60/732,292 | 2005-11-01 | ||
| CA2625844A CA2625844C (en) | 2005-11-01 | 2006-11-01 | Aerosol propellants comprising unsaturated fluorocarbons |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2625844A Division CA2625844C (en) | 2005-11-01 | 2006-11-01 | Aerosol propellants comprising unsaturated fluorocarbons |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2852198A1 true CA2852198A1 (en) | 2007-05-10 |
Family
ID=37831536
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2852198A Abandoned CA2852198A1 (en) | 2005-11-01 | 2006-11-01 | Aerosol propellants comprising unsaturated fluorocarbons |
| CA2625844A Active CA2625844C (en) | 2005-11-01 | 2006-11-01 | Aerosol propellants comprising unsaturated fluorocarbons |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2625844A Active CA2625844C (en) | 2005-11-01 | 2006-11-01 | Aerosol propellants comprising unsaturated fluorocarbons |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20070098646A1 (https=) |
| EP (2) | EP1954778B1 (https=) |
| JP (1) | JP5425470B2 (https=) |
| CN (2) | CN101300322B (https=) |
| CA (2) | CA2852198A1 (https=) |
| ES (2) | ES2698831T3 (https=) |
| WO (1) | WO2007053671A1 (https=) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7279451B2 (en) * | 2002-10-25 | 2007-10-09 | Honeywell International Inc. | Compositions containing fluorine substituted olefins |
| US20040089839A1 (en) * | 2002-10-25 | 2004-05-13 | Honeywell International, Inc. | Fluorinated alkene refrigerant compositions |
| US8033120B2 (en) * | 2002-10-25 | 2011-10-11 | Honeywell International Inc. | Compositions and methods containing fluorine substituted olefins |
| US7655610B2 (en) * | 2004-04-29 | 2010-02-02 | Honeywell International Inc. | Blowing agent compositions comprising fluorinated olefins and carbon dioxide |
| US9499729B2 (en) * | 2006-06-26 | 2016-11-22 | Honeywell International Inc. | Compositions and methods containing fluorine substituted olefins |
| US8574451B2 (en) * | 2005-06-24 | 2013-11-05 | Honeywell International Inc. | Trans-chloro-3,3,3-trifluoropropene for use in chiller applications |
| US20070098646A1 (en) | 2005-11-01 | 2007-05-03 | Nappa Mario J | Aerosol propellants comprising unsaturated fluorocarbons |
| US7708903B2 (en) | 2005-11-01 | 2010-05-04 | E.I. Du Pont De Nemours And Company | Compositions comprising fluoroolefins and uses thereof |
| CN101351537B (zh) * | 2005-11-01 | 2013-09-25 | 纳幕尔杜邦公司 | 包含不饱和氟化烃的溶剂组合物 |
| DE102006004870A1 (de) * | 2006-02-02 | 2007-08-16 | Siltronic Ag | Halbleiterschichtstruktur und Verfahren zur Herstellung einer Halbleiterschichtstruktur |
| ES2642570T3 (es) | 2006-02-28 | 2017-11-16 | The Chemours Company Fc, Llc | Composiciones azeotrópicas que comprenden compuestos fluorados para aplicaciones de limpieza |
| US8192723B2 (en) * | 2006-03-31 | 2012-06-05 | Reckitt Benckiser (Uk) Limited | Aerosol composition |
| US7597818B2 (en) * | 2007-02-27 | 2009-10-06 | Honeywell International Inc. | Azeotrope-like compositions of tetrafluoropropenes and bromofluoropropenes |
| CA2684290C (en) * | 2007-06-12 | 2016-09-06 | E. I. Du Pont De Nemours And Company | Azeotropic and azeotrope-like compositions of e-1,1,1,4,4,4-hexafluoro-2-butene |
| US20100210747A1 (en) * | 2007-07-20 | 2010-08-19 | E.I. Du Pont De Nemours And Company | Compositions and use of trans-1,1,1,4,4,4-hexafluoro-2-butene foam-forming composition in the preparation of polyisocyanate-based foams |
| US7641808B2 (en) * | 2007-08-23 | 2010-01-05 | E.I. Du Pont De Nemours And Company | Azeotropic compositions comprising fluorinated olefins for cleaning applications |
| CN101784650A (zh) * | 2007-08-23 | 2010-07-21 | 纳幕尔杜邦公司 | 用于清洁应用的包含氟化烯烃的共沸组合物 |
| MX2010002471A (es) * | 2007-09-06 | 2010-03-26 | Du Pont | Composiciones azeotropicas y similares a azeotropos de e-1,1,1,4,4,5,5,5-octafluoro-2-penteno. |
| AU2008331468B2 (en) | 2007-11-29 | 2015-02-05 | The Chemours Company Fc, Llc. | Compositions and use of cis-1,1,1,4,4,4-hexafluoro-2-butene foam-forming composition in the preparation of polyisocyanate-based foams |
| KR20160015399A (ko) | 2007-12-19 | 2016-02-12 | 이 아이 듀폰 디 네모아 앤드 캄파니 | Z-1,1,1,4,4,4-헥사플루오로-2-부텐 함유 공비 또는 공비-유사 혼합물을 함유하는 폼-형성 조성물 및 폴리아이소시아네이트-기재 폼의 제조에서의 그의 용도 |
| JP5586157B2 (ja) * | 2008-02-25 | 2014-09-10 | フマキラー株式会社 | 害虫駆除用エアゾール |
| JP2010077033A (ja) * | 2008-09-24 | 2010-04-08 | Central Glass Co Ltd | エアゾール組成物 |
| WO2010035701A1 (ja) * | 2008-09-24 | 2010-04-01 | セントラル硝子株式会社 | エアゾール組成物 |
| JP2010077036A (ja) * | 2008-09-24 | 2010-04-08 | Central Glass Co Ltd | エアゾール組成物 |
| JP2010077035A (ja) * | 2008-09-24 | 2010-04-08 | Central Glass Co Ltd | 殺虫用エアゾール組成物 |
| JP2010077034A (ja) * | 2008-09-24 | 2010-04-08 | Central Glass Co Ltd | エアゾール組成物 |
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| US20110147638A1 (en) * | 2009-06-26 | 2011-06-23 | E.I. Du Pont De Nemours And Company | Azeotropic and azeotrope-like compositions of z-1,1,1,4,4,4-hexafluoro-2-butene, trans-1,2-dichloroethylene, and cyclopentane |
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- 2006-11-01 CA CA2852198A patent/CA2852198A1/en not_active Abandoned
- 2006-11-01 ES ES11153118T patent/ES2698831T3/es active Active
- 2006-11-01 CN CN200680041068.8A patent/CN101300322B/zh active Active
- 2006-11-01 JP JP2008538989A patent/JP5425470B2/ja active Active
- 2006-11-01 EP EP06827265.7A patent/EP1954778B1/en active Active
- 2006-11-01 EP EP11153118.2A patent/EP2327753B1/en active Active
- 2006-11-01 WO PCT/US2006/042632 patent/WO2007053671A1/en not_active Ceased
- 2006-11-01 CN CN201510505763.6A patent/CN105154011B/zh active Active
- 2006-11-01 ES ES06827265.7T patent/ES2639404T3/es active Active
- 2006-11-01 CA CA2625844A patent/CA2625844C/en active Active
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2012
- 2012-08-24 US US13/594,007 patent/US8907145B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2327753B1 (en) | 2018-09-05 |
| EP2327753A3 (en) | 2014-12-10 |
| EP2327753A2 (en) | 2011-06-01 |
| ES2639404T3 (es) | 2017-10-26 |
| CA2625844C (en) | 2014-05-27 |
| US8907145B2 (en) | 2014-12-09 |
| JP5425470B2 (ja) | 2014-02-26 |
| US20070098646A1 (en) | 2007-05-03 |
| JP2009513813A (ja) | 2009-04-02 |
| US20120318828A1 (en) | 2012-12-20 |
| WO2007053671A1 (en) | 2007-05-10 |
| EP1954778B1 (en) | 2017-06-28 |
| EP1954778A1 (en) | 2008-08-13 |
| CN105154011A (zh) | 2015-12-16 |
| CN101300322A (zh) | 2008-11-05 |
| ES2698831T3 (es) | 2019-02-06 |
| CN101300322B (zh) | 2015-09-16 |
| CA2625844A1 (en) | 2007-05-10 |
| CN105154011B (zh) | 2017-10-20 |
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