CA2838017C - Multilayered valve metal coating for a surgical implant - Google Patents
Multilayered valve metal coating for a surgical implant Download PDFInfo
- Publication number
- CA2838017C CA2838017C CA2838017A CA2838017A CA2838017C CA 2838017 C CA2838017 C CA 2838017C CA 2838017 A CA2838017 A CA 2838017A CA 2838017 A CA2838017 A CA 2838017A CA 2838017 C CA2838017 C CA 2838017C
- Authority
- CA
- Canada
- Prior art keywords
- layer
- surgical implant
- pores
- valve metal
- implant according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000007943 implant Substances 0.000 title claims abstract description 107
- 229910052751 metal Inorganic materials 0.000 title claims abstract description 65
- 239000002184 metal Substances 0.000 title claims abstract description 65
- 238000000576 coating method Methods 0.000 title claims description 12
- 239000011248 coating agent Substances 0.000 title claims description 11
- 239000010410 layer Substances 0.000 claims abstract description 238
- 239000000463 material Substances 0.000 claims abstract description 116
- 239000000758 substrate Substances 0.000 claims abstract description 90
- 238000000034 method Methods 0.000 claims abstract description 46
- 239000002344 surface layer Substances 0.000 claims abstract description 36
- 229910044991 metal oxide Inorganic materials 0.000 claims abstract description 35
- 150000004706 metal oxides Chemical class 0.000 claims abstract description 35
- 230000008569 process Effects 0.000 claims abstract description 28
- 238000002048 anodisation reaction Methods 0.000 claims abstract description 20
- 238000004519 manufacturing process Methods 0.000 claims abstract description 15
- 229910052791 calcium Inorganic materials 0.000 claims abstract description 7
- 150000002500 ions Chemical class 0.000 claims abstract description 7
- 229910052698 phosphorus Inorganic materials 0.000 claims abstract description 7
- 238000010894 electron beam technology Methods 0.000 claims abstract description 4
- 238000010884 ion-beam technique Methods 0.000 claims abstract description 4
- 238000000678 plasma activation Methods 0.000 claims abstract description 4
- 239000011148 porous material Substances 0.000 claims description 200
- 229920006260 polyaryletherketone Polymers 0.000 claims description 66
- 239000007769 metal material Substances 0.000 claims description 31
- 239000004696 Poly ether ether ketone Substances 0.000 claims description 21
- 229920002530 polyetherether ketone Polymers 0.000 claims description 21
- 239000010936 titanium Substances 0.000 claims description 17
- -1 CrO2O3 Chemical compound 0.000 claims description 16
- 210000000988 bone and bone Anatomy 0.000 claims description 14
- 229920001652 poly(etherketoneketone) Polymers 0.000 claims description 14
- PBCFLUZVCVVTBY-UHFFFAOYSA-N tantalum pentoxide Inorganic materials O=[Ta](=O)O[Ta](=O)=O PBCFLUZVCVVTBY-UHFFFAOYSA-N 0.000 claims description 12
- 239000011247 coating layer Substances 0.000 claims description 11
- MCMNRKCIXSYSNV-UHFFFAOYSA-N Zirconium dioxide Chemical compound O=[Zr]=O MCMNRKCIXSYSNV-UHFFFAOYSA-N 0.000 claims description 9
- 229910052719 titanium Inorganic materials 0.000 claims description 9
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 8
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 claims description 8
- ZKATWMILCYLAPD-UHFFFAOYSA-N niobium pentoxide Chemical compound O=[Nb](=O)O[Nb](=O)=O ZKATWMILCYLAPD-UHFFFAOYSA-N 0.000 claims description 8
- 150000004767 nitrides Chemical class 0.000 claims description 8
- GGCZERPQGJTIQP-UHFFFAOYSA-N sodium;9,10-dioxoanthracene-2-sulfonic acid Chemical compound [Na+].C1=CC=C2C(=O)C3=CC(S(=O)(=O)O)=CC=C3C(=O)C2=C1 GGCZERPQGJTIQP-UHFFFAOYSA-N 0.000 claims description 7
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 6
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims description 6
- 239000011575 calcium Substances 0.000 claims description 6
- 238000000151 deposition Methods 0.000 claims description 6
- 230000008021 deposition Effects 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 238000005240 physical vapour deposition Methods 0.000 claims description 6
- 229910052726 zirconium Inorganic materials 0.000 claims description 6
- 229920008285 Poly(ether ketone) PEK Polymers 0.000 claims description 5
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 claims description 5
- 239000001506 calcium phosphate Substances 0.000 claims description 5
- 229910000389 calcium phosphate Inorganic materials 0.000 claims description 5
- 235000011010 calcium phosphates Nutrition 0.000 claims description 5
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 5
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 4
- 239000012790 adhesive layer Substances 0.000 claims description 4
- WMWLMWRWZQELOS-UHFFFAOYSA-N bismuth(iii) oxide Chemical compound O=[Bi]O[Bi]=O WMWLMWRWZQELOS-UHFFFAOYSA-N 0.000 claims description 4
- QXYJCZRRLLQGCR-UHFFFAOYSA-N dioxomolybdenum Chemical compound O=[Mo]=O QXYJCZRRLLQGCR-UHFFFAOYSA-N 0.000 claims description 4
- 229910052737 gold Inorganic materials 0.000 claims description 4
- JKQOBWVOAYFWKG-UHFFFAOYSA-N molybdenum trioxide Chemical compound O=[Mo](=O)=O JKQOBWVOAYFWKG-UHFFFAOYSA-N 0.000 claims description 4
- 229910052763 palladium Inorganic materials 0.000 claims description 4
- 229910052697 platinum Inorganic materials 0.000 claims description 4
- WOCIAKWEIIZHES-UHFFFAOYSA-N ruthenium(iv) oxide Chemical compound O=[Ru]=O WOCIAKWEIIZHES-UHFFFAOYSA-N 0.000 claims description 4
- WGLPBDUCMAPZCE-UHFFFAOYSA-N Trioxochromium Chemical compound O=[Cr](=O)=O WGLPBDUCMAPZCE-UHFFFAOYSA-N 0.000 claims description 3
- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 claims description 3
- 230000002378 acidificating effect Effects 0.000 claims description 3
- 229910052782 aluminium Inorganic materials 0.000 claims description 3
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 3
- 238000000541 cathodic arc deposition Methods 0.000 claims description 3
- 229910052681 coesite Inorganic materials 0.000 claims description 3
- 150000001875 compounds Chemical class 0.000 claims description 3
- 229910052906 cristobalite Inorganic materials 0.000 claims description 3
- 238000003618 dip coating Methods 0.000 claims description 3
- 238000005328 electron beam physical vapour deposition Methods 0.000 claims description 3
- 229910052735 hafnium Inorganic materials 0.000 claims description 3
- VBJZVLUMGGDVMO-UHFFFAOYSA-N hafnium atom Chemical compound [Hf] VBJZVLUMGGDVMO-UHFFFAOYSA-N 0.000 claims description 3
- 238000000168 high power impulse magnetron sputter deposition Methods 0.000 claims description 3
- 238000007654 immersion Methods 0.000 claims description 3
- 238000002513 implantation Methods 0.000 claims description 3
- 238000005468 ion implantation Methods 0.000 claims description 3
- 238000001755 magnetron sputter deposition Methods 0.000 claims description 3
- 229910052758 niobium Inorganic materials 0.000 claims description 3
- 239000010955 niobium Substances 0.000 claims description 3
- GUCVJGMIXFAOAE-UHFFFAOYSA-N niobium atom Chemical compound [Nb] GUCVJGMIXFAOAE-UHFFFAOYSA-N 0.000 claims description 3
- 238000000623 plasma-assisted chemical vapour deposition Methods 0.000 claims description 3
- 229920000548 poly(silane) polymer Polymers 0.000 claims description 3
- 238000004549 pulsed laser deposition Methods 0.000 claims description 3
- 238000004528 spin coating Methods 0.000 claims description 3
- 229910052682 stishovite Inorganic materials 0.000 claims description 3
- 229910052715 tantalum Inorganic materials 0.000 claims description 3
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 claims description 3
- 229910052905 tridymite Inorganic materials 0.000 claims description 3
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 claims description 3
- 229910052721 tungsten Inorganic materials 0.000 claims description 3
- 239000010937 tungsten Substances 0.000 claims description 3
- 229910052804 chromium Inorganic materials 0.000 claims description 2
- 229920001169 thermoplastic Polymers 0.000 claims description 2
- 239000004416 thermosoftening plastic Substances 0.000 claims description 2
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000000377 silicon dioxide Substances 0.000 claims 1
- 235000012239 silicon dioxide Nutrition 0.000 claims 1
- 239000004698 Polyethylene Substances 0.000 description 14
- 229920000573 polyethylene Polymers 0.000 description 14
- 239000012815 thermoplastic material Substances 0.000 description 12
- 229920000642 polymer Polymers 0.000 description 10
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical group [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 description 6
- 241000050051 Chelone glabra Species 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 4
- QDOXWKRWXJOMAK-UHFFFAOYSA-N dichromium trioxide Chemical compound O=[Cr]O[Cr]=O QDOXWKRWXJOMAK-UHFFFAOYSA-N 0.000 description 3
- 238000002595 magnetic resonance imaging Methods 0.000 description 3
- 210000000056 organ Anatomy 0.000 description 3
- 239000007921 spray Substances 0.000 description 3
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 239000003365 glass fiber Substances 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 239000006187 pill Substances 0.000 description 2
- 229910052710 silicon Inorganic materials 0.000 description 2
- 239000010703 silicon Substances 0.000 description 2
- 210000003625 skull Anatomy 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000004381 surface treatment Methods 0.000 description 2
- 229920000049 Carbon (fiber) Polymers 0.000 description 1
- 201000008450 Intracranial aneurysm Diseases 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
- 229910052586 apatite Inorganic materials 0.000 description 1
- 230000003416 augmentation Effects 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 239000004917 carbon fiber Substances 0.000 description 1
- 238000013132 cardiothoracic surgery Methods 0.000 description 1
- 238000002591 computed tomography Methods 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 210000003709 heart valve Anatomy 0.000 description 1
- 210000004394 hip joint Anatomy 0.000 description 1
- 208000003906 hydrocephalus Diseases 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 238000010883 osseointegration Methods 0.000 description 1
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 1
- 229920001643 poly(ether ketone) Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- YUYCVXFAYWRXLS-UHFFFAOYSA-N trimethoxysilane Chemical compound CO[SiH](OC)OC YUYCVXFAYWRXLS-UHFFFAOYSA-N 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C14/00—Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
- C23C14/06—Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the coating material
- C23C14/08—Oxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/082—Inorganic materials
- A61L31/088—Other specific inorganic materials not covered by A61L31/084 or A61L31/086
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/146—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/18—Materials at least partially X-ray or laser opaque
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C28/00—Coating for obtaining at least two superposed coatings either by methods not provided for in a single one of groups C23C2/00 - C23C26/00 or by combinations of methods provided for in subclasses C23C and C25C or C25D
- C23C28/30—Coatings combining at least one metallic layer and at least one inorganic non-metallic layer
- C23C28/32—Coatings combining at least one metallic layer and at least one inorganic non-metallic layer including at least one pure metallic layer
- C23C28/321—Coatings combining at least one metallic layer and at least one inorganic non-metallic layer including at least one pure metallic layer with at least one metal alloy layer
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C28/00—Coating for obtaining at least two superposed coatings either by methods not provided for in a single one of groups C23C2/00 - C23C26/00 or by combinations of methods provided for in subclasses C23C and C25C or C25D
- C23C28/30—Coatings combining at least one metallic layer and at least one inorganic non-metallic layer
- C23C28/32—Coatings combining at least one metallic layer and at least one inorganic non-metallic layer including at least one pure metallic layer
- C23C28/322—Coatings combining at least one metallic layer and at least one inorganic non-metallic layer including at least one pure metallic layer only coatings of metal elements only
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C28/00—Coating for obtaining at least two superposed coatings either by methods not provided for in a single one of groups C23C2/00 - C23C26/00 or by combinations of methods provided for in subclasses C23C and C25C or C25D
- C23C28/30—Coatings combining at least one metallic layer and at least one inorganic non-metallic layer
- C23C28/34—Coatings combining at least one metallic layer and at least one inorganic non-metallic layer including at least one inorganic non-metallic material layer, e.g. metal carbide, nitride, boride, silicide layer and their mixtures, enamels, phosphates and sulphates
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C28/00—Coating for obtaining at least two superposed coatings either by methods not provided for in a single one of groups C23C2/00 - C23C26/00 or by combinations of methods provided for in subclasses C23C and C25C or C25D
- C23C28/30—Coatings combining at least one metallic layer and at least one inorganic non-metallic layer
- C23C28/34—Coatings combining at least one metallic layer and at least one inorganic non-metallic layer including at least one inorganic non-metallic material layer, e.g. metal carbide, nitride, boride, silicide layer and their mixtures, enamels, phosphates and sulphates
- C23C28/345—Coatings combining at least one metallic layer and at least one inorganic non-metallic layer including at least one inorganic non-metallic material layer, e.g. metal carbide, nitride, boride, silicide layer and their mixtures, enamels, phosphates and sulphates with at least one oxide layer
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C28/00—Coating for obtaining at least two superposed coatings either by methods not provided for in a single one of groups C23C2/00 - C23C26/00 or by combinations of methods provided for in subclasses C23C and C25C or C25D
- C23C28/40—Coatings including alternating layers following a pattern, a periodic or defined repetition
- C23C28/42—Coatings including alternating layers following a pattern, a periodic or defined repetition characterized by the composition of the alternating layers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/44—Radioisotopes, radionuclides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/02—Methods for coating medical devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/04—Coatings containing a composite material such as inorganic/organic, i.e. material comprising different phases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/08—Coatings comprising two or more layers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/20—Materials or treatment for tissue regeneration for reconstruction of the heart, e.g. heart valves
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Metallurgy (AREA)
- Mechanical Engineering (AREA)
- Materials Engineering (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Chemistry (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Prostheses (AREA)
- Polymers & Plastics (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161492985P | 2011-06-03 | 2011-06-03 | |
| US61/492,985 | 2011-06-03 | ||
| PCT/US2012/040437 WO2012167063A1 (en) | 2011-06-03 | 2012-06-01 | Surgical implant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2838017A1 CA2838017A1 (en) | 2012-12-06 |
| CA2838017C true CA2838017C (en) | 2019-08-27 |
Family
ID=46276001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2838017A Active CA2838017C (en) | 2011-06-03 | 2012-06-01 | Multilayered valve metal coating for a surgical implant |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9283303B2 (enExample) |
| EP (1) | EP2714110B1 (enExample) |
| JP (1) | JP6054378B2 (enExample) |
| KR (1) | KR101951635B1 (enExample) |
| CN (1) | CN103561787B (enExample) |
| BR (1) | BR112013030971B1 (enExample) |
| CA (1) | CA2838017C (enExample) |
| TW (1) | TWI546090B (enExample) |
| WO (1) | WO2012167063A1 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11207109B2 (en) | 2010-10-20 | 2021-12-28 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| WO2012054742A2 (en) | 2010-10-20 | 2012-04-26 | BIOS2 Medical, Inc. | Implantable polymer for bone and vascular lesions |
| US11291483B2 (en) | 2010-10-20 | 2022-04-05 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants |
| US10525169B2 (en) | 2010-10-20 | 2020-01-07 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US11058796B2 (en) | 2010-10-20 | 2021-07-13 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| WO2015095745A1 (en) | 2010-10-20 | 2015-06-25 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US11484627B2 (en) | 2010-10-20 | 2022-11-01 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| WO2014190289A2 (en) | 2013-05-23 | 2014-11-27 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants |
| TWI546090B (zh) | 2011-06-03 | 2016-08-21 | 星瑟斯有限公司 | 外科用之植入物 |
| EP2819620A4 (en) | 2012-02-29 | 2015-11-04 | 206 Ortho Inc | METHOD AND APPARATUS FOR TREATING BONE FRACTURES, INCLUDING THE USE OF COMPOSITE IMPLANTS |
| CN103242551B (zh) * | 2013-05-20 | 2015-02-25 | 中国科学院上海硅酸盐研究所 | 注入钛离子对聚醚醚酮表面进行改性的方法 |
| CN103225067A (zh) * | 2013-05-20 | 2013-07-31 | 中国科学院上海硅酸盐研究所 | 注入钙离子对聚醚醚酮表面进行改性的方法 |
| US10000843B2 (en) * | 2013-09-13 | 2018-06-19 | DePuy Synthes Products, Inc. | Coating process for non-conductive substrates and devices made from the coating process |
| CN103526259B (zh) * | 2013-10-08 | 2016-08-17 | 广州市健齿生物科技有限公司 | 一种钛合金手术器械表面处理工艺 |
| CN103614699B (zh) * | 2013-12-16 | 2015-11-18 | 中国科学院上海硅酸盐研究所 | 注入钽离子对聚醚醚酮表面进行改性的方法及改性的聚醚醚酮材料 |
| CN103816569B (zh) * | 2014-02-28 | 2016-05-11 | 丹阳纳瑞康纳米科技有限公司 | 一种气相Ag纳米颗粒处理的植入体医用材料的方法 |
| JP2015229792A (ja) * | 2014-06-05 | 2015-12-21 | オリンパス株式会社 | インプラントとその製造方法 |
| WO2016109481A2 (en) * | 2014-12-30 | 2016-07-07 | DePuy Synthes Products, Inc. | Coatings for surgical instruments |
| KR102383501B1 (ko) * | 2015-01-08 | 2022-04-07 | 삼성전자주식회사 | 다층 박막, 그 제조 방법 및 이를 포함하는 전자 제품 |
| CN106390191B (zh) * | 2016-06-21 | 2019-06-04 | 太仓碧奇新材料研发有限公司 | 钬钨钴合金/聚硅氧烷支架材料的制备方法 |
| CN105920666B (zh) * | 2016-06-21 | 2019-04-02 | 太仓碧奇新材料研发有限公司 | 镧钨镍合金/聚碳酸酯支架材料的制备方法 |
| CN106039399B (zh) * | 2016-06-21 | 2018-12-14 | 太仓碧奇新材料研发有限公司 | 镝钼镍合金/聚甲基丙烯酸甲酯支架材料的制备方法 |
| CN106075569B (zh) * | 2016-06-21 | 2018-12-14 | 太仓碧奇新材料研发有限公司 | 铽锰镍合金/聚醚醚酮支架材料的制备方法 |
| CN105920664B (zh) * | 2016-06-21 | 2019-04-02 | 太仓碧奇新材料研发有限公司 | 镨铁镍合金/聚苯乙烯支架材料的制备方法 |
| CN105963775B (zh) * | 2016-06-21 | 2018-12-14 | 太仓碧奇新材料研发有限公司 | 钐锰钴合金/聚氨酯支架材料的制备方法 |
| CN105999402B (zh) * | 2016-06-21 | 2018-12-14 | 太仓碧奇新材料研发有限公司 | 钆钼钴合金/聚酰胺支架材料的制备方法 |
| CN105920665B (zh) * | 2016-06-21 | 2018-12-14 | 太仓碧奇新材料研发有限公司 | 铕锡钴合金/聚四氟乙烯支架材料的制备方法 |
| CN107773782A (zh) * | 2016-08-24 | 2018-03-09 | 上海双申医疗器械股份有限公司 | 一种提高纯钛和钛合金表面骨细胞相容性和抑菌性的方法 |
| EP3292877A1 (de) * | 2016-09-09 | 2018-03-14 | Universität Basel | Implantat oder osteosynthese und verfahren zu dessen herstellung |
| EP3813698A4 (en) * | 2018-05-09 | 2022-06-01 | 206 Ortho, Inc. | METHOD AND APPARATUS FOR TREATMENT OF FRACTURES AND/OR FOR STRENGTHENING AND/OR GROWING BONES, INCLUDING THE PROVISION AND USE OF COMPOSITE IMPLANTS, AND NOVEL COMPOSITE STRUCTURES FOR USE FOR MEDICAL AND NON-MEDICAL APPLICATIONS |
| EP3858596A4 (en) * | 2018-09-28 | 2021-11-24 | Mitsubishi Chemical Corporation | ANTIMICROBIAL MATERIAL, LAMINATE BODY, ANTIMICROBIAL LAMINATE BODY, MEDICAL ITEM, ANTIMICROBIAL MATERIAL PRODUCTION PROCESS, ANTIMICROBIAL LAMINATE BODY PRODUCTION PROCESS, AND ANTIMICROBIAL PROCESS |
| CN109338252B (zh) * | 2018-11-30 | 2020-11-06 | 昆明理工大学 | 一种锆基多孔非晶合金及制备方法 |
| CN109852943B (zh) * | 2019-03-15 | 2020-06-09 | 成都理工大学 | 核用锆合金表面CrN涂层的制备方法及产品 |
| CN110393821B (zh) * | 2019-08-01 | 2020-10-02 | 西北有色金属研究院 | 多孔氧化锌和氧化钽涂层共修饰的人工植入体及其制备方法 |
| CN110499493B (zh) * | 2019-08-30 | 2021-08-31 | 西安工程大学 | 一种制备可抑制杀菌活性的Ta2O5@Ag双相微纳结构的方法 |
| CN111074226B (zh) * | 2020-02-10 | 2021-02-02 | 兰州理工大学 | 一种碳基复合薄膜及其制备方法 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2189815B (en) | 1986-03-24 | 1990-10-10 | Permelec Electrode Ltd | Titanium composite materials coated with calcium phosphate compound and process for production thereof |
| JP2956318B2 (ja) | 1991-10-07 | 1999-10-04 | 三菱マテリアル株式会社 | 燐酸カルシウム系セラミックス層被覆ＴｉまたはＴｉ合金製インプラントおよびその製造法 |
| JPH05202207A (ja) | 1992-01-28 | 1993-08-10 | Yokohama Rubber Co Ltd:The | ポリエーテルエーテルケトン樹脂成形品の表面処理法 |
| JPH0817894B2 (ja) * | 1992-01-29 | 1996-02-28 | 株式会社栗田機械製作所 | フィルタプレスの濾過方法 |
| US5242880A (en) | 1992-05-27 | 1993-09-07 | Eastman Kodak Company | Photoactive catalyst of barium phosphate or calcium phosphate supported on anatase titanium dioxide |
| US6509098B1 (en) * | 1995-11-17 | 2003-01-21 | Massachusetts Institute Of Technology | Poly(ethylene oxide) coated surfaces |
| WO1999011202A1 (en) * | 1997-09-05 | 1999-03-11 | Icet, Inc. | Biomimetic calcium phosphate implant coatings and methods for making the same |
| SE513556C2 (sv) * | 1997-11-11 | 2000-10-02 | Nobel Biocare Ab | Implantatelement med tunt ytskickt applicerat genom het isostatisk pressning |
| DE19830530A1 (de) | 1998-07-08 | 2000-01-13 | Merck Patent Gmbh | Herstellung von Kalzium-Phosphor-Schichten auf Titan durch Ionenimplantation |
| US6322588B1 (en) * | 1999-08-17 | 2001-11-27 | St. Jude Medical, Inc. | Medical devices with metal/polymer composites |
| JP2001259017A (ja) | 2000-03-19 | 2001-09-25 | Fumio Watari | 生体材料用リン酸カルシウム−チタン系複合材料およびその製造方法 |
| US7048541B2 (en) * | 2000-04-04 | 2006-05-23 | Nobel Biocare Ab | Implant having attachment and hole-insert parts, and method for producing such an implant |
| US20050019365A1 (en) * | 2001-04-02 | 2005-01-27 | Frauchiger Vinzenz M. | Bioactive surface layer, particularly for medical implants and prostheses |
| WO2002078785A2 (en) * | 2001-04-02 | 2002-10-10 | Radiovascular, Inc. | A brachytherapy device and method of use |
| EP1293219A1 (de) | 2001-09-17 | 2003-03-19 | Matthias Prof. Dr. Epple | Biomedizinisches Erzeugnis mit einem eine Nickel-Titan-Legierung enthaltenden Substrat und einer Calciumphosphat enthaltenden überdeckenden Schicht |
| US20040210289A1 (en) | 2002-03-04 | 2004-10-21 | Xingwu Wang | Novel nanomagnetic particles |
| KR20040015854A (ko) | 2002-08-14 | 2004-02-21 | 박영준 | 티타늄 표면 위에 코팅된 티탄산 바륨 박막의 분극처리에 의한 생체유사용액에서의 칼슘-포스페이트 생성 증진 |
| US6974532B2 (en) | 2003-05-01 | 2005-12-13 | New York University | Method for producing adherent coatings of calcium phosphate phases on titanium and titanium alloy substrates by electrochemical deposition |
| US6801424B1 (en) * | 2003-05-30 | 2004-10-05 | Medtronic, Inc. | Electrolytic capacitor for use in an implantable medical device |
| US6807048B1 (en) * | 2003-05-30 | 2004-10-19 | Medtronic, Inc. | Electrolytic capacitor for use in an implantable medical device |
| US7309232B2 (en) * | 2003-10-10 | 2007-12-18 | Dentigenix Inc. | Methods for treating dental conditions using tissue scaffolds |
| US20050089711A1 (en) * | 2003-10-23 | 2005-04-28 | Joachim Hossick-Schott | Methods of producing carbon layers on titanium metal |
| US7687102B2 (en) * | 2003-10-23 | 2010-03-30 | Medtronic, Inc. | Methods and apparatus for producing carbon cathodes |
| US20050100578A1 (en) * | 2003-11-06 | 2005-05-12 | Schmid Steven R. | Bone and tissue scaffolding and method for producing same |
| WO2005048897A1 (en) | 2003-11-18 | 2005-06-02 | Quantum Orthopedics | Osteoconductive integrated spinal cage and method of making same |
| DE10361942A1 (de) | 2003-12-24 | 2005-07-21 | Restate Patent Ag | Radioopaker Marker für medizinische Implantate |
| US20060091020A1 (en) * | 2004-10-29 | 2006-05-04 | Medtronic, Inc. | Processes and systems for formation of high voltage, anodic oxide on a valve metal anode |
| CN101415459B (zh) * | 2004-08-25 | 2014-11-05 | 麦克罗文逊股份有限公司 | 可植入物装置的热脱离系统 |
| GB0422666D0 (en) * | 2004-10-12 | 2004-11-10 | Benoist Girard Sas | Prosthetic acetabular cups |
| RU2291918C1 (ru) | 2005-05-31 | 2007-01-20 | Институт физики прочности и материаловедения Сибирского отделения Российской академии наук (ИФПМ СО РАН) | Кальций-фосфатное покрытие на титане и титановых сплавах и способ его нанесения |
| EP1931401A2 (en) * | 2005-09-09 | 2008-06-18 | University of Arkansas at Little Rock | System and method for tissue generation and bone regeneration |
| US7491246B2 (en) * | 2006-03-31 | 2009-02-17 | Medtronic, Inc. | Capacitor electrodes produced with atomic layer deposition for use in implantable medical devices |
| ITBO20070436A1 (it) | 2007-06-22 | 2008-12-23 | Azionaria Materiale Ospeda Lie | Metodo per produrre superfici per manufatti metallici |
| RU2348744C1 (ru) | 2007-07-11 | 2009-03-10 | Институт химии Дальневосточного отделения Российской академии наук (статус государственного учреждения) (Институт химии ДВО РАН) | Способ нанесения кальций-фосфатного покрытия на имплантаты из титана и его сплавов |
| EP2200669B1 (en) * | 2007-08-20 | 2011-12-28 | Smith & Nephew, PLC | Method of forming a bioactive implant material |
| CA2697712A1 (en) | 2007-08-24 | 2009-03-05 | Brown University | A method for producing nanostructures on a surface of a medical implant |
| SE531779C2 (sv) | 2007-11-26 | 2009-08-04 | Promimic Ab | Framställning av kalciumfosfatpartiklar i nanostorlek som pulver eller beläggning via bifunktionella prekursorer |
| JP5207480B2 (ja) | 2008-05-30 | 2013-06-12 | 株式会社ナントー精密 | インプラント体及びその製造方法並びに歯科用インプラント |
| CN102049064B (zh) | 2009-11-06 | 2016-08-03 | 中国科学院上海硅酸盐研究所 | 一种硅掺杂多孔纳米氧化钛涂层及其制备方法 |
| BR112012030011A2 (pt) * | 2010-05-25 | 2016-08-02 | 3M Innovative Properties Co | revestimentos antimicrobianos |
| CN101880890A (zh) | 2010-07-08 | 2010-11-10 | 电子科技大学 | 医用钛表面制备羟基磷灰石/氧化锆梯度涂层的电化学方法 |
| CN101879332A (zh) * | 2010-07-13 | 2010-11-10 | 北京大学 | 含有氟磷灰石和二氧化钛的聚醚醚酮复合材料及制备方法 |
| CN102008751B (zh) * | 2010-11-24 | 2014-01-08 | 北京道淼浩博科技发展有限公司 | 一种生物降解支架复合材料及其制备方法 |
| TWI546090B (zh) | 2011-06-03 | 2016-08-21 | 星瑟斯有限公司 | 外科用之植入物 |
-
2012
- 2012-06-01 TW TW101119762A patent/TWI546090B/zh not_active IP Right Cessation
- 2012-06-01 WO PCT/US2012/040437 patent/WO2012167063A1/en not_active Ceased
- 2012-06-01 KR KR1020147000091A patent/KR101951635B1/ko not_active Expired - Fee Related
- 2012-06-01 JP JP2014513740A patent/JP6054378B2/ja not_active Expired - Fee Related
- 2012-06-01 EP EP12727509.7A patent/EP2714110B1/en active Active
- 2012-06-01 CA CA2838017A patent/CA2838017C/en active Active
- 2012-06-01 BR BR112013030971A patent/BR112013030971B1/pt not_active IP Right Cessation
- 2012-06-01 US US13/486,479 patent/US9283303B2/en active Active
- 2012-06-01 CN CN201280027210.9A patent/CN103561787B/zh not_active Expired - Fee Related
-
2016
- 2016-03-11 US US15/067,273 patent/US9702037B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP6054378B2 (ja) | 2016-12-27 |
| TWI546090B (zh) | 2016-08-21 |
| EP2714110B1 (en) | 2018-03-21 |
| CN103561787B (zh) | 2016-08-17 |
| US9283303B2 (en) | 2016-03-15 |
| CN103561787A (zh) | 2014-02-05 |
| EP2714110A1 (en) | 2014-04-09 |
| BR112013030971A2 (pt) | 2016-11-29 |
| US20160194746A1 (en) | 2016-07-07 |
| US20120310368A1 (en) | 2012-12-06 |
| US9702037B2 (en) | 2017-07-11 |
| BR112013030971B1 (pt) | 2019-10-22 |
| KR101951635B1 (ko) | 2019-02-25 |
| JP2014523279A (ja) | 2014-09-11 |
| KR20140033197A (ko) | 2014-03-17 |
| WO2012167063A1 (en) | 2012-12-06 |
| CA2838017A1 (en) | 2012-12-06 |
| TW201311301A (zh) | 2013-03-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2838017C (en) | Multilayered valve metal coating for a surgical implant | |
| Sheng et al. | Advanced surface modification for 3D-printed titanium alloy implant interface functionalization | |
| CN105939691B (zh) | 椎间体应用的脊柱植入物 | |
| Durham III et al. | Hydroxyapatite coating on PEEK implants: Biomechanical and histological study in a rabbit model | |
| Johansson et al. | Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia | |
| Cvrček et al. | Plasma modified polymeric materials for implant applications | |
| Cristea et al. | Tantalum based materials for implants and prostheses applications | |
| JP2021049360A (ja) | 生体用抗菌インプラント、ならびに関連する材料、装置及び方法 | |
| EP2332589A2 (en) | Methods for coating implants | |
| US20150075995A1 (en) | Coating Process for Non-Conductive Substrates and Devices Made From the Coating Process | |
| Hanawa | Transition of surface modification of titanium for medical and dental use | |
| EP3220969B1 (en) | Antibacterial osseoconductive thin film for implant | |
| Shivgotra et al. | Advancement in Biomaterials in the Form of Implants | |
| Yuvaraj et al. | A comprehensive analysis of bioimplant manufacturing advancements: a state-of-the-art review | |
| CN118201568A (zh) | 植入成像系统 | |
| TWM537881U (zh) | 外科手術植入物結構 | |
| KR102331708B1 (ko) | 다공성 나노 복합구조의 ha코팅층이 형성된 peek기재 | |
| Han | Osteoblast Responses to Different Surface Morphology and Roughness of 3D-printed PEEK Implants and Prosthesis | |
| WO2018046655A1 (de) | Implantat oder osteosynthese und verfahren zu dessen herstellung | |
| Koonrungsesomboon et al. | Effect of immersion time in simulated body fluid on adhesion strength of hydrothermally treated hydroxyapatite-titanium nitride films on polyetheretherketones | |
| Pesode et al. | Biocompatible Coatings on Implants | |
| Bagaria et al. | Predicting the Future in Orthopedic Implantology | |
| Agrawal et al. | POLYETHERETHERKETONE (PEEK): AN INNOVATION IN DENTISTRY. | |
| Iwasaki et al. | Bone-Bonding Ability of Anodized Titanium Plate Loaded With Hydroxyapatite Particles | |
| Shivaram | TiO2 Nanotubes on Titanium for Early Stage Osseointegration: Understanding the Mechanical Stability, Bone Bonding and Infection Control Ability |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20170524 |