CN103561787B - 外科植入物 - Google Patents
外科植入物 Download PDFInfo
- Publication number
- CN103561787B CN103561787B CN201280027210.9A CN201280027210A CN103561787B CN 103561787 B CN103561787 B CN 103561787B CN 201280027210 A CN201280027210 A CN 201280027210A CN 103561787 B CN103561787 B CN 103561787B
- Authority
- CN
- China
- Prior art keywords
- layer
- hole
- valve metal
- surgical implant
- paek
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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- 239000000463 material Substances 0.000 claims abstract description 120
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- 229910052751 metal Inorganic materials 0.000 claims abstract description 62
- 239000002184 metal Substances 0.000 claims abstract description 62
- 238000000034 method Methods 0.000 claims abstract description 51
- 230000004913 activation Effects 0.000 claims abstract description 38
- 239000002344 surface layer Substances 0.000 claims abstract description 34
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- 150000004706 metal oxides Chemical class 0.000 claims abstract description 32
- 230000008569 process Effects 0.000 claims abstract description 20
- 238000010894 electron beam technology Methods 0.000 claims abstract description 6
- 229910001424 calcium ion Inorganic materials 0.000 claims abstract description 4
- 238000010884 ion-beam technique Methods 0.000 claims abstract description 4
- 229920006260 polyaryletherketone Polymers 0.000 claims description 59
- 239000007769 metal material Substances 0.000 claims description 31
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- 239000004416 thermosoftening plastic Substances 0.000 claims description 13
- 229910052719 titanium Inorganic materials 0.000 claims description 11
- PBCFLUZVCVVTBY-UHFFFAOYSA-N tantalum pentoxide Inorganic materials O=[Ta](=O)O[Ta](=O)=O PBCFLUZVCVVTBY-UHFFFAOYSA-N 0.000 claims description 10
- 150000002500 ions Chemical class 0.000 claims description 8
- 150000004767 nitrides Chemical class 0.000 claims description 8
- 229910052737 gold Inorganic materials 0.000 claims description 6
- 239000001506 calcium phosphate Substances 0.000 claims description 5
- 229910000389 calcium phosphate Inorganic materials 0.000 claims description 5
- 235000011010 calcium phosphates Nutrition 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 5
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- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 description 6
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- WMWLMWRWZQELOS-UHFFFAOYSA-N bismuth(iii) oxide Chemical compound O=[Bi]O[Bi]=O WMWLMWRWZQELOS-UHFFFAOYSA-N 0.000 description 4
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- QDOXWKRWXJOMAK-UHFFFAOYSA-N dichromium trioxide Chemical compound O=[Cr]O[Cr]=O QDOXWKRWXJOMAK-UHFFFAOYSA-N 0.000 description 4
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- GUCVJGMIXFAOAE-UHFFFAOYSA-N niobium atom Chemical compound [Nb] GUCVJGMIXFAOAE-UHFFFAOYSA-N 0.000 description 2
- 238000004549 pulsed laser deposition Methods 0.000 description 2
- WOCIAKWEIIZHES-UHFFFAOYSA-N ruthenium(IV) oxide Inorganic materials O=[Ru]=O WOCIAKWEIIZHES-UHFFFAOYSA-N 0.000 description 2
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- 229910052726 zirconium Inorganic materials 0.000 description 2
- 229920000049 Carbon (fiber) Polymers 0.000 description 1
- 201000008450 Intracranial aneurysm Diseases 0.000 description 1
- 235000019738 Limestone Nutrition 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
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- 239000003513 alkali Substances 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 238000003287 bathing Methods 0.000 description 1
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- 239000004917 carbon fiber Substances 0.000 description 1
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- 238000002591 computed tomography Methods 0.000 description 1
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- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 description 1
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- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
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- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C14/00—Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
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- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C28/00—Coating for obtaining at least two superposed coatings either by methods not provided for in a single one of groups C23C2/00 - C23C26/00 or by combinations of methods provided for in subclasses C23C and C25C or C25D
- C23C28/30—Coatings combining at least one metallic layer and at least one inorganic non-metallic layer
- C23C28/34—Coatings combining at least one metallic layer and at least one inorganic non-metallic layer including at least one inorganic non-metallic material layer, e.g. metal carbide, nitride, boride, silicide layer and their mixtures, enamels, phosphates and sulphates
- C23C28/345—Coatings combining at least one metallic layer and at least one inorganic non-metallic layer including at least one inorganic non-metallic material layer, e.g. metal carbide, nitride, boride, silicide layer and their mixtures, enamels, phosphates and sulphates with at least one oxide layer
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- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C28/00—Coating for obtaining at least two superposed coatings either by methods not provided for in a single one of groups C23C2/00 - C23C26/00 or by combinations of methods provided for in subclasses C23C and C25C or C25D
- C23C28/40—Coatings including alternating layers following a pattern, a periodic or defined repetition
- C23C28/42—Coatings including alternating layers following a pattern, a periodic or defined repetition characterized by the composition of the alternating layers
-
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/44—Radioisotopes, radionuclides
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/02—Methods for coating medical devices
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/04—Coatings containing a composite material such as inorganic/organic, i.e. material comprising different phases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/08—Coatings comprising two or more layers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/20—Materials or treatment for tissue regeneration for reconstruction of the heart, e.g. heart valves
Landscapes
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- Veterinary Medicine (AREA)
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- Epidemiology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Mechanical Engineering (AREA)
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- Transplantation (AREA)
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- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Prostheses (AREA)
- Polymers & Plastics (AREA)
- Materials For Medical Uses (AREA)
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| US61/492985 | 2011-06-03 | ||
| PCT/US2012/040437 WO2012167063A1 (en) | 2011-06-03 | 2012-06-01 | Surgical implant |
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| CN103561787A CN103561787A (zh) | 2014-02-05 |
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| WO2012054742A2 (en) | 2010-10-20 | 2012-04-26 | BIOS2 Medical, Inc. | Implantable polymer for bone and vascular lesions |
| US11291483B2 (en) | 2010-10-20 | 2022-04-05 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants |
| US10525169B2 (en) | 2010-10-20 | 2020-01-07 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US11058796B2 (en) | 2010-10-20 | 2021-07-13 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| WO2015095745A1 (en) | 2010-10-20 | 2015-06-25 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US11484627B2 (en) | 2010-10-20 | 2022-11-01 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| WO2014190289A2 (en) | 2013-05-23 | 2014-11-27 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants |
| TWI546090B (zh) | 2011-06-03 | 2016-08-21 | 星瑟斯有限公司 | 外科用之植入物 |
| EP2819620A4 (en) | 2012-02-29 | 2015-11-04 | 206 Ortho Inc | METHOD AND APPARATUS FOR TREATING BONE FRACTURES, INCLUDING THE USE OF COMPOSITE IMPLANTS |
| CN103242551B (zh) * | 2013-05-20 | 2015-02-25 | 中国科学院上海硅酸盐研究所 | 注入钛离子对聚醚醚酮表面进行改性的方法 |
| CN103225067A (zh) * | 2013-05-20 | 2013-07-31 | 中国科学院上海硅酸盐研究所 | 注入钙离子对聚醚醚酮表面进行改性的方法 |
| US10000843B2 (en) * | 2013-09-13 | 2018-06-19 | DePuy Synthes Products, Inc. | Coating process for non-conductive substrates and devices made from the coating process |
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| CN103614699B (zh) * | 2013-12-16 | 2015-11-18 | 中国科学院上海硅酸盐研究所 | 注入钽离子对聚醚醚酮表面进行改性的方法及改性的聚醚醚酮材料 |
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| CN106075569B (zh) * | 2016-06-21 | 2018-12-14 | 太仓碧奇新材料研发有限公司 | 铽锰镍合金/聚醚醚酮支架材料的制备方法 |
| CN105920664B (zh) * | 2016-06-21 | 2019-04-02 | 太仓碧奇新材料研发有限公司 | 镨铁镍合金/聚苯乙烯支架材料的制备方法 |
| CN105963775B (zh) * | 2016-06-21 | 2018-12-14 | 太仓碧奇新材料研发有限公司 | 钐锰钴合金/聚氨酯支架材料的制备方法 |
| CN105999402B (zh) * | 2016-06-21 | 2018-12-14 | 太仓碧奇新材料研发有限公司 | 钆钼钴合金/聚酰胺支架材料的制备方法 |
| CN105920665B (zh) * | 2016-06-21 | 2018-12-14 | 太仓碧奇新材料研发有限公司 | 铕锡钴合金/聚四氟乙烯支架材料的制备方法 |
| CN107773782A (zh) * | 2016-08-24 | 2018-03-09 | 上海双申医疗器械股份有限公司 | 一种提高纯钛和钛合金表面骨细胞相容性和抑菌性的方法 |
| EP3292877A1 (de) * | 2016-09-09 | 2018-03-14 | Universität Basel | Implantat oder osteosynthese und verfahren zu dessen herstellung |
| EP3813698A4 (en) * | 2018-05-09 | 2022-06-01 | 206 Ortho, Inc. | METHOD AND APPARATUS FOR TREATMENT OF FRACTURES AND/OR FOR STRENGTHENING AND/OR GROWING BONES, INCLUDING THE PROVISION AND USE OF COMPOSITE IMPLANTS, AND NOVEL COMPOSITE STRUCTURES FOR USE FOR MEDICAL AND NON-MEDICAL APPLICATIONS |
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2012
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1505532A (zh) * | 2001-04-02 | 2004-06-16 | ˹��̩��ҽѧ�ɷݹ�˾ | 生物活性表面层,特别是用于医用植入体和假牙的生物活性表面层 |
| CN101415459A (zh) * | 2004-08-25 | 2009-04-22 | 麦克罗文逊股份有限公司 | 可植入物装置的热脱离系统 |
| EP1647242A1 (en) * | 2004-10-12 | 2006-04-19 | Benoist Girard Sas | Prosthetic acetabular cups |
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| CN102049064A (zh) * | 2009-11-06 | 2011-05-11 | 中国科学院上海硅酸盐研究所 | 一种硅掺杂多孔纳米氧化钛涂层及其制备方法 |
| CN101880890A (zh) * | 2010-07-08 | 2010-11-10 | 电子科技大学 | 医用钛表面制备羟基磷灰石/氧化锆梯度涂层的电化学方法 |
| CN101879332A (zh) * | 2010-07-13 | 2010-11-10 | 北京大学 | 含有氟磷灰石和二氧化钛的聚醚醚酮复合材料及制备方法 |
| CN102008751A (zh) * | 2010-11-24 | 2011-04-13 | 北京道淼浩博科技发展有限公司 | 一种生物降解支架复合材料及其制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6054378B2 (ja) | 2016-12-27 |
| TWI546090B (zh) | 2016-08-21 |
| EP2714110B1 (en) | 2018-03-21 |
| US9283303B2 (en) | 2016-03-15 |
| CN103561787A (zh) | 2014-02-05 |
| EP2714110A1 (en) | 2014-04-09 |
| BR112013030971A2 (pt) | 2016-11-29 |
| US20160194746A1 (en) | 2016-07-07 |
| US20120310368A1 (en) | 2012-12-06 |
| US9702037B2 (en) | 2017-07-11 |
| CA2838017C (en) | 2019-08-27 |
| BR112013030971B1 (pt) | 2019-10-22 |
| KR101951635B1 (ko) | 2019-02-25 |
| JP2014523279A (ja) | 2014-09-11 |
| KR20140033197A (ko) | 2014-03-17 |
| WO2012167063A1 (en) | 2012-12-06 |
| CA2838017A1 (en) | 2012-12-06 |
| TW201311301A (zh) | 2013-03-16 |
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