CA2837534A1 - Lysyl oxidase-like 2 assay and methods of use thereof - Google Patents

Lysyl oxidase-like 2 assay and methods of use thereof Download PDF

Info

Publication number
CA2837534A1
CA2837534A1 CA2837534A CA2837534A CA2837534A1 CA 2837534 A1 CA2837534 A1 CA 2837534A1 CA 2837534 A CA2837534 A CA 2837534A CA 2837534 A CA2837534 A CA 2837534A CA 2837534 A1 CA2837534 A1 CA 2837534A1
Authority
CA
Canada
Prior art keywords
loxl2
antibody
disease
individual
level
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2837534A
Other languages
English (en)
French (fr)
Inventor
Victoria Smith
Joanne I. Adamkewicz
Susan K. Lyman
Jason CHIEN
Xiaoming Li
Lixin Shao
Jeffrey D. Bornstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gilead Biologics Inc
Original Assignee
Gilead Biologics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46208194&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2837534(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gilead Biologics Inc filed Critical Gilead Biologics Inc
Publication of CA2837534A1 publication Critical patent/CA2837534A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Silicon Polymers (AREA)
CA2837534A 2011-06-01 2012-06-01 Lysyl oxidase-like 2 assay and methods of use thereof Abandoned CA2837534A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161492210P 2011-06-01 2011-06-01
US61/492,210 2011-06-01
US201161550895P 2011-10-24 2011-10-24
US61/550,895 2011-10-24
US201161578813P 2011-12-21 2011-12-21
US61/578,813 2011-12-21
PCT/US2012/040585 WO2012167181A1 (en) 2011-06-01 2012-06-01 Lysyl oxidase-like 2 assay and methods of use thereof

Publications (1)

Publication Number Publication Date
CA2837534A1 true CA2837534A1 (en) 2012-12-06

Family

ID=46208194

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2837534A Abandoned CA2837534A1 (en) 2011-06-01 2012-06-01 Lysyl oxidase-like 2 assay and methods of use thereof

Country Status (25)

Country Link
US (3) US20140206017A1 (enExample)
EP (1) EP2714744A1 (enExample)
JP (3) JP2014523521A (enExample)
KR (1) KR20140048156A (enExample)
CN (1) CN103946241A (enExample)
AP (1) AP2013007285A0 (enExample)
AR (1) AR086657A1 (enExample)
AU (2) AU2012261883A1 (enExample)
BR (1) BR112013030682A2 (enExample)
CA (1) CA2837534A1 (enExample)
CL (1) CL2013003445A1 (enExample)
CO (1) CO6940375A2 (enExample)
CR (1) CR20130657A (enExample)
EA (1) EA201391627A1 (enExample)
EC (1) ECSP13013092A (enExample)
IL (1) IL229631A0 (enExample)
MA (1) MA35212B1 (enExample)
MD (1) MD20130098A2 (enExample)
MX (1) MX2013013905A (enExample)
PE (1) PE20141450A1 (enExample)
PH (1) PH12013502490A1 (enExample)
TW (1) TW201319572A (enExample)
UY (1) UY34115A (enExample)
WO (1) WO2012167181A1 (enExample)
ZA (1) ZA201308812B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030114410A1 (en) 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
CN110372795A (zh) 2007-08-02 2019-10-25 吉利德生物制剂公司 Lox和loxl2抑制剂及其应用
WO2010080769A2 (en) 2009-01-06 2010-07-15 Arresto Biosciences, Inc. Chemotherapeutic methods and compositions
RU2012110585A (ru) 2009-08-21 2013-09-27 Джилид Байолоджикс, Инк. Каталичические домены лизилоксидазы и loxl2
RU2015108348A (ru) 2010-02-04 2015-07-20 Джилид Байолоджикс, Инк. Антитела, связывающиеся с лизилоксидазоподобным ферментом-2 (loxl2), и способы их применения
SG11201503065PA (en) * 2012-10-30 2015-05-28 Gilead Sciences Inc Therapeutic and diagnostic methods related to lysyl oxidase-like 2 (loxl2)
US20150342943A1 (en) 2014-06-03 2015-12-03 Gilead Sciences, Inc. Methods of treating liver disease
SG11201609522TA (en) * 2014-06-11 2016-12-29 Gilead Sciences Inc Methods for treating cardiovascular diseases
MA41252A (fr) 2014-12-23 2017-10-31 Gilead Sciences Inc Formes solides d'un inhibiteur d'ask 1
CA3016081A1 (en) 2016-03-04 2017-09-08 Gilead Sciences, Inc. Compositions and combinations of autotaxin inhibitors
JP2019513737A (ja) 2016-04-08 2019-05-30 ギリアード サイエンシーズ, インコーポレイテッド がん、炎症性疾患および自己免疫疾患を処置するための組成物および方法
GB201704206D0 (en) 2017-03-16 2017-05-03 Nordic Bioscience As Lysyl oxidase like-2 assay
WO2023091479A1 (en) * 2021-11-17 2023-05-25 AmMax Bio, Inc. Detection and treatment of idiopathic pulmonary fibrosis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6352862B1 (en) * 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
FI92882C (fi) * 1992-12-29 1995-01-10 Medix Biochemica Ab Oy Kertakäyttöinen testiliuska ja menetelmä sen valmistamiseksi
US20030114410A1 (en) * 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
CN110372795A (zh) * 2007-08-02 2019-10-25 吉利德生物制剂公司 Lox和loxl2抑制剂及其应用
JP2010038735A (ja) * 2008-08-05 2010-02-18 Terumo Corp 腹膜機能の評価方法および腹膜機能評価用イムノクロマト試験紙
BR112012008080A2 (pt) * 2009-08-21 2017-07-04 Gilead Biologics Inc ensaios de rastreamento in vivo.
RU2015108348A (ru) * 2010-02-04 2015-07-20 Джилид Байолоджикс, Инк. Антитела, связывающиеся с лизилоксидазоподобным ферментом-2 (loxl2), и способы их применения
US9556882B2 (en) * 2011-05-10 2017-01-31 Borgwarner Inc. Turbocharger with variable turbine geometry

Also Published As

Publication number Publication date
UY34115A (es) 2013-01-03
CL2013003445A1 (es) 2014-07-25
PE20141450A1 (es) 2014-11-06
KR20140048156A (ko) 2014-04-23
ZA201308812B (en) 2014-08-27
US20170269085A1 (en) 2017-09-21
EP2714744A1 (en) 2014-04-09
WO2012167181A1 (en) 2012-12-06
ECSP13013092A (es) 2014-08-29
MA35212B1 (fr) 2014-06-02
TW201319572A (zh) 2013-05-16
CN103946241A (zh) 2014-07-23
AU2016244254A1 (en) 2016-11-03
CR20130657A (es) 2014-05-16
JP2018049033A (ja) 2018-03-29
MX2013013905A (es) 2014-05-14
NZ618682A (en) 2016-04-29
BR112013030682A2 (pt) 2016-12-06
AU2016244254B2 (en) 2018-10-18
AR086657A1 (es) 2014-01-15
AP2013007285A0 (en) 2013-11-30
JP2014523521A (ja) 2014-09-11
AU2012261883A1 (en) 2013-05-02
IL229631A0 (en) 2014-01-30
US20140206017A1 (en) 2014-07-24
PH12013502490A1 (en) 2014-01-20
MD20130098A2 (ro) 2014-06-30
CO6940375A2 (es) 2014-05-09
EA201391627A1 (ru) 2014-08-29
US20120309020A1 (en) 2012-12-06
JP2016164578A (ja) 2016-09-08

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20200831