CA2837534A1 - Lysyl oxidase-like 2 assay and methods of use thereof - Google Patents
Lysyl oxidase-like 2 assay and methods of use thereof Download PDFInfo
- Publication number
- CA2837534A1 CA2837534A1 CA2837534A CA2837534A CA2837534A1 CA 2837534 A1 CA2837534 A1 CA 2837534A1 CA 2837534 A CA2837534 A CA 2837534A CA 2837534 A CA2837534 A CA 2837534A CA 2837534 A1 CA2837534 A1 CA 2837534A1
- Authority
- CA
- Canada
- Prior art keywords
- loxl2
- antibody
- disease
- individual
- level
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Silicon Polymers (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161492210P | 2011-06-01 | 2011-06-01 | |
| US61/492,210 | 2011-06-01 | ||
| US201161550895P | 2011-10-24 | 2011-10-24 | |
| US61/550,895 | 2011-10-24 | ||
| US201161578813P | 2011-12-21 | 2011-12-21 | |
| US61/578,813 | 2011-12-21 | ||
| PCT/US2012/040585 WO2012167181A1 (en) | 2011-06-01 | 2012-06-01 | Lysyl oxidase-like 2 assay and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2837534A1 true CA2837534A1 (en) | 2012-12-06 |
Family
ID=46208194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2837534A Abandoned CA2837534A1 (en) | 2011-06-01 | 2012-06-01 | Lysyl oxidase-like 2 assay and methods of use thereof |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US20140206017A1 (enExample) |
| EP (1) | EP2714744A1 (enExample) |
| JP (3) | JP2014523521A (enExample) |
| KR (1) | KR20140048156A (enExample) |
| CN (1) | CN103946241A (enExample) |
| AP (1) | AP2013007285A0 (enExample) |
| AR (1) | AR086657A1 (enExample) |
| AU (2) | AU2012261883A1 (enExample) |
| BR (1) | BR112013030682A2 (enExample) |
| CA (1) | CA2837534A1 (enExample) |
| CL (1) | CL2013003445A1 (enExample) |
| CO (1) | CO6940375A2 (enExample) |
| CR (1) | CR20130657A (enExample) |
| EA (1) | EA201391627A1 (enExample) |
| EC (1) | ECSP13013092A (enExample) |
| IL (1) | IL229631A0 (enExample) |
| MA (1) | MA35212B1 (enExample) |
| MD (1) | MD20130098A2 (enExample) |
| MX (1) | MX2013013905A (enExample) |
| PE (1) | PE20141450A1 (enExample) |
| PH (1) | PH12013502490A1 (enExample) |
| TW (1) | TW201319572A (enExample) |
| UY (1) | UY34115A (enExample) |
| WO (1) | WO2012167181A1 (enExample) |
| ZA (1) | ZA201308812B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030114410A1 (en) | 2000-08-08 | 2003-06-19 | Technion Research And Development Foundation Ltd. | Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis |
| CA2693310C (en) * | 2007-08-02 | 2018-11-27 | Arresto Biosciences, Inc. | Lox and loxl2 inhibitors, antibodies and uses thereof |
| US9107935B2 (en) | 2009-01-06 | 2015-08-18 | Gilead Biologics, Inc. | Chemotherapeutic methods and compositions |
| CA2771702A1 (en) | 2009-08-21 | 2011-02-24 | Gilead Biologics, Inc. | Catalytic domains from lysyl oxidase and loxl2 |
| BR112012019693A2 (pt) | 2010-02-04 | 2017-06-20 | Gilead Biologics Inc | anticorpos que se ligam à lisil oxidase-like 2 (loxl2) e métodos de uso para eles. |
| WO2014070939A1 (en) * | 2012-10-30 | 2014-05-08 | Gilead Sciences, Inc. | Therapeutic and diagnostic methods related to lysyl oxidase-like 2 (loxl2) |
| WO2015187499A1 (en) | 2014-06-03 | 2015-12-10 | Gilead Sciences, Inc. | Use of an ask1 inhibitor for the treatment of liver disease, optionally in combination with a loxl2 inhibitor |
| EA201692202A1 (ru) | 2014-06-11 | 2017-06-30 | Джилид Сайэнс, Инк. | Способы лечения сердечно-сосудистых заболеваний |
| MA41252A (fr) | 2014-12-23 | 2017-10-31 | Gilead Sciences Inc | Formes solides d'un inhibiteur d'ask 1 |
| JP2019510752A (ja) | 2016-03-04 | 2019-04-18 | ギリアード サイエンシーズ， インコーポレイテッド | オートタキシン阻害剤の組成物及び合剤 |
| JP2019513737A (ja) | 2016-04-08 | 2019-05-30 | ギリアード サイエンシーズ， インコーポレイテッド | がん、炎症性疾患および自己免疫疾患を処置するための組成物および方法 |
| GB201704206D0 (en) | 2017-03-16 | 2017-05-03 | Nordic Bioscience As | Lysyl oxidase like-2 assay |
| US20230152330A1 (en) * | 2021-11-17 | 2023-05-18 | AmMax Bio, Inc. | Detection and treatment of idiopathic pulmonary fibrosis |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6352862B1 (en) * | 1989-02-17 | 2002-03-05 | Unilever Patent Holdings B.V. | Analytical test device for imuno assays and methods of using same |
| FI92882C (fi) * | 1992-12-29 | 1995-01-10 | Medix Biochemica Ab Oy | Kertakäyttöinen testiliuska ja menetelmä sen valmistamiseksi |
| US20030114410A1 (en) * | 2000-08-08 | 2003-06-19 | Technion Research And Development Foundation Ltd. | Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis |
| CA2693310C (en) | 2007-08-02 | 2018-11-27 | Arresto Biosciences, Inc. | Lox and loxl2 inhibitors, antibodies and uses thereof |
| JP2010038735A (ja) * | 2008-08-05 | 2010-02-18 | Terumo Corp | 腹膜機能の評価方法および腹膜機能評価用イムノクロマト試験紙 |
| RU2012110580A (ru) * | 2009-08-21 | 2013-09-27 | Джилид Байолоджикс, Инк. | Способы скрининга in vivo |
| BR112012019693A2 (pt) * | 2010-02-04 | 2017-06-20 | Gilead Biologics Inc | anticorpos que se ligam à lisil oxidase-like 2 (loxl2) e métodos de uso para eles. |
| US9556882B2 (en) * | 2011-05-10 | 2017-01-31 | Borgwarner Inc. | Turbocharger with variable turbine geometry |
-
2012
- 2012-06-01 AP AP2013007285A patent/AP2013007285A0/xx unknown
- 2012-06-01 PE PE2013002739A patent/PE20141450A1/es not_active Application Discontinuation
- 2012-06-01 CN CN201280037235.7A patent/CN103946241A/zh active Pending
- 2012-06-01 BR BR112013030682A patent/BR112013030682A2/pt not_active IP Right Cessation
- 2012-06-01 MD MDA20130098A patent/MD20130098A2/ro not_active Application Discontinuation
- 2012-06-01 TW TW101119847A patent/TW201319572A/zh unknown
- 2012-06-01 EA EA201391627A patent/EA201391627A1/ru unknown
- 2012-06-01 US US14/122,984 patent/US20140206017A1/en not_active Abandoned
- 2012-06-01 CA CA2837534A patent/CA2837534A1/en not_active Abandoned
- 2012-06-01 PH PH1/2013/502490A patent/PH12013502490A1/en unknown
- 2012-06-01 AU AU2012261883A patent/AU2012261883A1/en not_active Abandoned
- 2012-06-01 US US13/487,109 patent/US20120309020A1/en not_active Abandoned
- 2012-06-01 WO PCT/US2012/040585 patent/WO2012167181A1/en not_active Ceased
- 2012-06-01 EP EP12725601.4A patent/EP2714744A1/en not_active Withdrawn
- 2012-06-01 KR KR1020137034711A patent/KR20140048156A/ko not_active Withdrawn
- 2012-06-01 UY UY0001034115A patent/UY34115A/es not_active Application Discontinuation
- 2012-06-01 JP JP2014513770A patent/JP2014523521A/ja not_active Withdrawn
- 2012-06-01 MX MX2013013905A patent/MX2013013905A/es not_active Application Discontinuation
- 2012-06-01 AR ARP120101959A patent/AR086657A1/es unknown
-
2013
- 2013-11-25 ZA ZA2013/08812A patent/ZA201308812B/en unknown
- 2013-11-26 IL IL229631A patent/IL229631A0/en unknown
- 2013-11-29 CL CL2013003445A patent/CL2013003445A1/es unknown
- 2013-12-13 CR CR20130657A patent/CR20130657A/es unknown
- 2013-12-19 EC ECSP13013092 patent/ECSP13013092A/es unknown
- 2013-12-27 CO CO13301122A patent/CO6940375A2/es unknown
- 2013-12-30 MA MA36627A patent/MA35212B1/fr unknown
-
2016
- 2016-06-09 JP JP2016115175A patent/JP2016164578A/ja active Pending
- 2016-10-12 AU AU2016244254A patent/AU2016244254B2/en not_active Ceased
- 2016-12-01 US US15/366,986 patent/US20170269085A1/en not_active Abandoned
-
2017
- 2017-11-16 JP JP2017221000A patent/JP2018049033A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX2013013905A (es) | 2014-05-14 |
| US20170269085A1 (en) | 2017-09-21 |
| AR086657A1 (es) | 2014-01-15 |
| KR20140048156A (ko) | 2014-04-23 |
| JP2016164578A (ja) | 2016-09-08 |
| IL229631A0 (en) | 2014-01-30 |
| AU2016244254A1 (en) | 2016-11-03 |
| MD20130098A2 (ro) | 2014-06-30 |
| AU2016244254B2 (en) | 2018-10-18 |
| JP2014523521A (ja) | 2014-09-11 |
| NZ618682A (en) | 2016-04-29 |
| BR112013030682A2 (pt) | 2016-12-06 |
| UY34115A (es) | 2013-01-03 |
| WO2012167181A1 (en) | 2012-12-06 |
| CL2013003445A1 (es) | 2014-07-25 |
| AU2012261883A1 (en) | 2013-05-02 |
| AP2013007285A0 (en) | 2013-11-30 |
| ZA201308812B (en) | 2014-08-27 |
| JP2018049033A (ja) | 2018-03-29 |
| EA201391627A1 (ru) | 2014-08-29 |
| CR20130657A (es) | 2014-05-16 |
| US20120309020A1 (en) | 2012-12-06 |
| CO6940375A2 (es) | 2014-05-09 |
| PH12013502490A1 (en) | 2014-01-20 |
| MA35212B1 (fr) | 2014-06-02 |
| EP2714744A1 (en) | 2014-04-09 |
| CN103946241A (zh) | 2014-07-23 |
| TW201319572A (zh) | 2013-05-16 |
| US20140206017A1 (en) | 2014-07-24 |
| PE20141450A1 (es) | 2014-11-06 |
| ECSP13013092A (es) | 2014-08-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20200831 |