JP2014523521A - リシルオキシダーゼ様2のアッセイおよびその使用の方法 - Google Patents

リシルオキシダーゼ様2のアッセイおよびその使用の方法 Download PDF

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Publication number
JP2014523521A
JP2014523521A JP2014513770A JP2014513770A JP2014523521A JP 2014523521 A JP2014523521 A JP 2014523521A JP 2014513770 A JP2014513770 A JP 2014513770A JP 2014513770 A JP2014513770 A JP 2014513770A JP 2014523521 A JP2014523521 A JP 2014523521A
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loxl2
antibody
disease
level
individual
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JP2014523521A5 (enExample
Inventor
ビクトリア スミス,
ジョアン アイ. アダムケウィックス,
スーザン ケイ. ライマン,
ジェイソン チエン,
シャオミン リ,
リーシン シャオ,
ジェフリー ディー. ボーンスタイン,
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ギリアード バイオロジックス, インコーポレイテッド
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Application filed by ギリアード バイオロジックス, インコーポレイテッド filed Critical ギリアード バイオロジックス, インコーポレイテッド
Publication of JP2014523521A publication Critical patent/JP2014523521A/ja
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Silicon Polymers (AREA)
JP2014513770A 2011-06-01 2012-06-01 リシルオキシダーゼ様2のアッセイおよびその使用の方法 Withdrawn JP2014523521A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161492210P 2011-06-01 2011-06-01
US61/492,210 2011-06-01
US201161550895P 2011-10-24 2011-10-24
US61/550,895 2011-10-24
US201161578813P 2011-12-21 2011-12-21
US61/578,813 2011-12-21
PCT/US2012/040585 WO2012167181A1 (en) 2011-06-01 2012-06-01 Lysyl oxidase-like 2 assay and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016115175A Division JP2016164578A (ja) 2011-06-01 2016-06-09 リシルオキシダーゼ様2のアッセイおよびその使用の方法

Publications (2)

Publication Number Publication Date
JP2014523521A true JP2014523521A (ja) 2014-09-11
JP2014523521A5 JP2014523521A5 (enExample) 2015-06-18

Family

ID=46208194

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2014513770A Withdrawn JP2014523521A (ja) 2011-06-01 2012-06-01 リシルオキシダーゼ様2のアッセイおよびその使用の方法
JP2016115175A Pending JP2016164578A (ja) 2011-06-01 2016-06-09 リシルオキシダーゼ様2のアッセイおよびその使用の方法
JP2017221000A Pending JP2018049033A (ja) 2011-06-01 2017-11-16 リシルオキシダーゼ様2のアッセイおよびその使用の方法

Family Applications After (2)

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JP2016115175A Pending JP2016164578A (ja) 2011-06-01 2016-06-09 リシルオキシダーゼ様2のアッセイおよびその使用の方法
JP2017221000A Pending JP2018049033A (ja) 2011-06-01 2017-11-16 リシルオキシダーゼ様2のアッセイおよびその使用の方法

Country Status (25)

Country Link
US (3) US20140206017A1 (enExample)
EP (1) EP2714744A1 (enExample)
JP (3) JP2014523521A (enExample)
KR (1) KR20140048156A (enExample)
CN (1) CN103946241A (enExample)
AP (1) AP2013007285A0 (enExample)
AR (1) AR086657A1 (enExample)
AU (2) AU2012261883A1 (enExample)
BR (1) BR112013030682A2 (enExample)
CA (1) CA2837534A1 (enExample)
CL (1) CL2013003445A1 (enExample)
CO (1) CO6940375A2 (enExample)
CR (1) CR20130657A (enExample)
EA (1) EA201391627A1 (enExample)
EC (1) ECSP13013092A (enExample)
IL (1) IL229631A0 (enExample)
MA (1) MA35212B1 (enExample)
MD (1) MD20130098A2 (enExample)
MX (1) MX2013013905A (enExample)
PE (1) PE20141450A1 (enExample)
PH (1) PH12013502490A1 (enExample)
TW (1) TW201319572A (enExample)
UY (1) UY34115A (enExample)
WO (1) WO2012167181A1 (enExample)
ZA (1) ZA201308812B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020514369A (ja) * 2017-03-16 2020-05-21 ノルディック・ビオサイエンス・エー/エスNordic Bioscience A/S リシルオキシダーゼ様2アッセイ

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030114410A1 (en) 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
CN110372795A (zh) 2007-08-02 2019-10-25 吉利德生物制剂公司 Lox和loxl2抑制剂及其应用
WO2010080769A2 (en) 2009-01-06 2010-07-15 Arresto Biosciences, Inc. Chemotherapeutic methods and compositions
RU2012110585A (ru) 2009-08-21 2013-09-27 Джилид Байолоджикс, Инк. Каталичические домены лизилоксидазы и loxl2
RU2015108348A (ru) 2010-02-04 2015-07-20 Джилид Байолоджикс, Инк. Антитела, связывающиеся с лизилоксидазоподобным ферментом-2 (loxl2), и способы их применения
SG11201503065PA (en) * 2012-10-30 2015-05-28 Gilead Sciences Inc Therapeutic and diagnostic methods related to lysyl oxidase-like 2 (loxl2)
US20150342943A1 (en) 2014-06-03 2015-12-03 Gilead Sciences, Inc. Methods of treating liver disease
SG11201609522TA (en) * 2014-06-11 2016-12-29 Gilead Sciences Inc Methods for treating cardiovascular diseases
MA41252A (fr) 2014-12-23 2017-10-31 Gilead Sciences Inc Formes solides d'un inhibiteur d'ask 1
CA3016081A1 (en) 2016-03-04 2017-09-08 Gilead Sciences, Inc. Compositions and combinations of autotaxin inhibitors
JP2019513737A (ja) 2016-04-08 2019-05-30 ギリアード サイエンシーズ, インコーポレイテッド がん、炎症性疾患および自己免疫疾患を処置するための組成物および方法
WO2023091479A1 (en) * 2021-11-17 2023-05-25 AmMax Bio, Inc. Detection and treatment of idiopathic pulmonary fibrosis

Citations (3)

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Publication number Priority date Publication date Assignee Title
JP2010038735A (ja) * 2008-08-05 2010-02-18 Terumo Corp 腹膜機能の評価方法および腹膜機能評価用イムノクロマト試験紙
JP2010535205A (ja) * 2007-08-02 2010-11-18 アレスト バイオサイエンシズ,インク. Loxおよびloxl2阻害剤ならびにこれらの使用
US20110044981A1 (en) * 2009-08-21 2011-02-24 Spangler Rhyannon Methods and compositions for treatment of pulmonary fibrotic disorders

Family Cites Families (5)

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Publication number Priority date Publication date Assignee Title
US6352862B1 (en) * 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
FI92882C (fi) * 1992-12-29 1995-01-10 Medix Biochemica Ab Oy Kertakäyttöinen testiliuska ja menetelmä sen valmistamiseksi
US20030114410A1 (en) * 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
RU2015108348A (ru) * 2010-02-04 2015-07-20 Джилид Байолоджикс, Инк. Антитела, связывающиеся с лизилоксидазоподобным ферментом-2 (loxl2), и способы их применения
US9556882B2 (en) * 2011-05-10 2017-01-31 Borgwarner Inc. Turbocharger with variable turbine geometry

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010535205A (ja) * 2007-08-02 2010-11-18 アレスト バイオサイエンシズ,インク. Loxおよびloxl2阻害剤ならびにこれらの使用
JP2010038735A (ja) * 2008-08-05 2010-02-18 Terumo Corp 腹膜機能の評価方法および腹膜機能評価用イムノクロマト試験紙
US20110044981A1 (en) * 2009-08-21 2011-02-24 Spangler Rhyannon Methods and compositions for treatment of pulmonary fibrotic disorders

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020514369A (ja) * 2017-03-16 2020-05-21 ノルディック・ビオサイエンス・エー/エスNordic Bioscience A/S リシルオキシダーゼ様2アッセイ

Also Published As

Publication number Publication date
UY34115A (es) 2013-01-03
CL2013003445A1 (es) 2014-07-25
PE20141450A1 (es) 2014-11-06
KR20140048156A (ko) 2014-04-23
ZA201308812B (en) 2014-08-27
US20170269085A1 (en) 2017-09-21
EP2714744A1 (en) 2014-04-09
WO2012167181A1 (en) 2012-12-06
ECSP13013092A (es) 2014-08-29
MA35212B1 (fr) 2014-06-02
TW201319572A (zh) 2013-05-16
CN103946241A (zh) 2014-07-23
AU2016244254A1 (en) 2016-11-03
CR20130657A (es) 2014-05-16
JP2018049033A (ja) 2018-03-29
MX2013013905A (es) 2014-05-14
NZ618682A (en) 2016-04-29
BR112013030682A2 (pt) 2016-12-06
AU2016244254B2 (en) 2018-10-18
AR086657A1 (es) 2014-01-15
AP2013007285A0 (en) 2013-11-30
AU2012261883A1 (en) 2013-05-02
IL229631A0 (en) 2014-01-30
US20140206017A1 (en) 2014-07-24
PH12013502490A1 (en) 2014-01-20
CA2837534A1 (en) 2012-12-06
MD20130098A2 (ro) 2014-06-30
CO6940375A2 (es) 2014-05-09
EA201391627A1 (ru) 2014-08-29
US20120309020A1 (en) 2012-12-06
JP2016164578A (ja) 2016-09-08

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