MD20130098A2 - Test pentru determinarea lizil oxidazei-2 şi metode de utilizare a acestuia - Google Patents

Test pentru determinarea lizil oxidazei-2 şi metode de utilizare a acestuia

Info

Publication number
MD20130098A2
MD20130098A2 MDA20130098A MD20130098A MD20130098A2 MD 20130098 A2 MD20130098 A2 MD 20130098A2 MD A20130098 A MDA20130098 A MD A20130098A MD 20130098 A MD20130098 A MD 20130098A MD 20130098 A2 MD20130098 A2 MD 20130098A2
Authority
MD
Moldova
Prior art keywords
assay
lysyl oxidase
methods
loxl2
polypeptides
Prior art date
Application number
MDA20130098A
Other languages
English (en)
Russian (ru)
Inventor
Виктория СМИТ
Джоан И. Адамкевич
Сьюзен ЛИМАН
Джейсон ЧИЭНЬ
Сяомин Ли
Лисинь Шао
Джеффри БОРНШТАЙН
Original Assignee
Gilead Biologics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46208194&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MD20130098(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gilead Biologics, Inc. filed Critical Gilead Biologics, Inc.
Publication of MD20130098A2 publication Critical patent/MD20130098A2/ro

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Silicon Polymers (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Prezenta invenţie se referă la un test pentru detectarea şi/sau cuantificarea polipeptidelor lizil oxidazei-2 circulante (LOXL2) la om. Analiza este utilă pentru aplicaţiile diagnostice şi prognostice, care sunt de asemenea prevăzute.
MDA20130098A 2011-06-01 2012-06-01 Test pentru determinarea lizil oxidazei-2 şi metode de utilizare a acestuia MD20130098A2 (ro)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161492210P 2011-06-01 2011-06-01
US201161550895P 2011-10-24 2011-10-24
US201161578813P 2011-12-21 2011-12-21
PCT/US2012/040585 WO2012167181A1 (en) 2011-06-01 2012-06-01 Lysyl oxidase-like 2 assay and methods of use thereof

Publications (1)

Publication Number Publication Date
MD20130098A2 true MD20130098A2 (ro) 2014-06-30

Family

ID=46208194

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20130098A MD20130098A2 (ro) 2011-06-01 2012-06-01 Test pentru determinarea lizil oxidazei-2 şi metode de utilizare a acestuia

Country Status (24)

Country Link
US (3) US20120309020A1 (ro)
EP (1) EP2714744A1 (ro)
JP (3) JP2014523521A (ro)
KR (1) KR20140048156A (ro)
CN (1) CN103946241A (ro)
AP (1) AP2013007285A0 (ro)
AR (1) AR086657A1 (ro)
AU (2) AU2012261883A1 (ro)
BR (1) BR112013030682A2 (ro)
CA (1) CA2837534A1 (ro)
CL (1) CL2013003445A1 (ro)
CO (1) CO6940375A2 (ro)
CR (1) CR20130657A (ro)
EA (1) EA201391627A1 (ro)
EC (1) ECSP13013092A (ro)
IL (1) IL229631A0 (ro)
MA (1) MA35212B1 (ro)
MD (1) MD20130098A2 (ro)
MX (1) MX2013013905A (ro)
PE (1) PE20141450A1 (ro)
TW (1) TW201319572A (ro)
UY (1) UY34115A (ro)
WO (1) WO2012167181A1 (ro)
ZA (1) ZA201308812B (ro)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030114410A1 (en) 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
JP5312459B2 (ja) 2007-08-02 2013-10-09 ジリード バイオロジクス，インク． Ｌｏｘおよびｌｏｘｌ２阻害剤ならびにこれらの使用
US9107935B2 (en) 2009-01-06 2015-08-18 Gilead Biologics, Inc. Chemotherapeutic methods and compositions
AU2010284036B2 (en) 2009-08-21 2014-12-18 Gilead Biologics, Inc. Catalytic domains from lysyl oxidase and LOXL2
SG183174A1 (en) 2010-02-04 2012-09-27 Gilead Biologics Inc Antibodies that bind to lysyl oxidase-like 2 (loxl2) and methods of use therefor
EP2914632A1 (en) * 2012-10-30 2015-09-09 Gilead Sciences, Inc. Therapeutic and diagnostic methods related to lysyl oxidase-like 2 (loxl2)
US20150342943A1 (en) 2014-06-03 2015-12-03 Gilead Sciences, Inc. Methods of treating liver disease
SG11201609522TA (en) 2014-06-11 2016-12-29 Gilead Sciences Inc Methods for treating cardiovascular diseases
MA41252A (fr) 2014-12-23 2017-10-31 Gilead Sciences Inc Formes solides d'un inhibiteur d'ask 1
JP2019510752A (ja) 2016-03-04 2019-04-18 ギリアード サイエンシーズ， インコーポレイテッド オートタキシン阻害剤の組成物及び合剤
WO2017177179A1 (en) 2016-04-08 2017-10-12 Gilead Sciences, Inc. Compositions and methods for treating cancer, inflammatory diseases and autoimmune diseases
GB201704206D0 (en) 2017-03-16 2017-05-03 Nordic Bioscience As Lysyl oxidase like-2 assay
WO2023091479A1 (en) * 2021-11-17 2023-05-25 AmMax Bio, Inc. Detection and treatment of idiopathic pulmonary fibrosis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6352862B1 (en) * 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
FI92882C (fi) * 1992-12-29 1995-01-10 Medix Biochemica Ab Oy Kertakäyttöinen testiliuska ja menetelmä sen valmistamiseksi
US20030114410A1 (en) * 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
JP5312459B2 (ja) * 2007-08-02 2013-10-09 ジリード バイオロジクス，インク． Ｌｏｘおよびｌｏｘｌ２阻害剤ならびにこれらの使用
JP2010038735A (ja) * 2008-08-05 2010-02-18 Terumo Corp 腹膜機能の評価方法および腹膜機能評価用イムノクロマト試験紙
RU2561672C2 (ru) * 2009-08-21 2015-08-27 Джилид Байолоджикс, Инк. Способы и композиции для лечения фиброзных заболеваний легких
SG183174A1 (en) * 2010-02-04 2012-09-27 Gilead Biologics Inc Antibodies that bind to lysyl oxidase-like 2 (loxl2) and methods of use therefor
US9556882B2 (en) * 2011-05-10 2017-01-31 Borgwarner Inc. Turbocharger with variable turbine geometry

Also Published As

Publication number Publication date
AU2016244254A1 (en) 2016-11-03
JP2016164578A (ja) 2016-09-08
MX2013013905A (es) 2014-05-14
US20140206017A1 (en) 2014-07-24
JP2014523521A (ja) 2014-09-11
ECSP13013092A (es) 2014-08-29
CR20130657A (es) 2014-05-16
AU2016244254B2 (en) 2018-10-18
JP2018049033A (ja) 2018-03-29
MA35212B1 (fr) 2014-06-02
EP2714744A1 (en) 2014-04-09
PE20141450A1 (es) 2014-11-06
AR086657A1 (es) 2014-01-15
TW201319572A (zh) 2013-05-16
US20170269085A1 (en) 2017-09-21
CN103946241A (zh) 2014-07-23
BR112013030682A2 (pt) 2016-12-06
CO6940375A2 (es) 2014-05-09
WO2012167181A1 (en) 2012-12-06
AP2013007285A0 (en) 2013-11-30
NZ618682A (en) 2016-04-29
CL2013003445A1 (es) 2014-07-25
UY34115A (es) 2013-01-03
IL229631A0 (en) 2014-01-30
US20120309020A1 (en) 2012-12-06
AU2012261883A1 (en) 2013-05-02
ZA201308812B (en) 2014-08-27
KR20140048156A (ko) 2014-04-23
CA2837534A1 (en) 2012-12-06
EA201391627A1 (ru) 2014-08-29

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Legal Events

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FA9A Abandonment or withdrawal of application (patent for invention)