AR086657A1 - Ensayo de la lisil oxidasa-like 2 y sus metodos de empleo - Google Patents
Ensayo de la lisil oxidasa-like 2 y sus metodos de empleoInfo
- Publication number
- AR086657A1 AR086657A1 ARP120101959A ARP120101959A AR086657A1 AR 086657 A1 AR086657 A1 AR 086657A1 AR P120101959 A ARP120101959 A AR P120101959A AR P120101959 A ARP120101959 A AR P120101959A AR 086657 A1 AR086657 A1 AR 086657A1
- Authority
- AR
- Argentina
- Prior art keywords
- loxl2
- individual
- antibody
- disease
- level
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- GBFLZEXEOZUWRN-VKHMYHEASA-N S-carboxymethyl-L-cysteine Chemical compound OC(=O)[C@@H](N)CSCC(O)=O GBFLZEXEOZUWRN-VKHMYHEASA-N 0.000 title 1
- 229960004399 carbocisteine Drugs 0.000 title 1
- 101001043352 Homo sapiens Lysyl oxidase homolog 2 Proteins 0.000 abstract 15
- 102100021948 Lysyl oxidase homolog 2 Human genes 0.000 abstract 15
- 239000000523 sample Substances 0.000 abstract 8
- 201000010099 disease Diseases 0.000 abstract 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 5
- 239000007788 liquid Substances 0.000 abstract 5
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 239000012472 biological sample Substances 0.000 abstract 2
- 230000003176 fibrotic effect Effects 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 239000012530 fluid Substances 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Silicon Polymers (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161492210P | 2011-06-01 | 2011-06-01 | |
| US201161550895P | 2011-10-24 | 2011-10-24 | |
| US201161578813P | 2011-12-21 | 2011-12-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR086657A1 true AR086657A1 (es) | 2014-01-15 |
Family
ID=46208194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120101959A AR086657A1 (es) | 2011-06-01 | 2012-06-01 | Ensayo de la lisil oxidasa-like 2 y sus metodos de empleo |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US20140206017A1 (enExample) |
| EP (1) | EP2714744A1 (enExample) |
| JP (3) | JP2014523521A (enExample) |
| KR (1) | KR20140048156A (enExample) |
| CN (1) | CN103946241A (enExample) |
| AP (1) | AP2013007285A0 (enExample) |
| AR (1) | AR086657A1 (enExample) |
| AU (2) | AU2012261883A1 (enExample) |
| BR (1) | BR112013030682A2 (enExample) |
| CA (1) | CA2837534A1 (enExample) |
| CL (1) | CL2013003445A1 (enExample) |
| CO (1) | CO6940375A2 (enExample) |
| CR (1) | CR20130657A (enExample) |
| EA (1) | EA201391627A1 (enExample) |
| EC (1) | ECSP13013092A (enExample) |
| IL (1) | IL229631A0 (enExample) |
| MA (1) | MA35212B1 (enExample) |
| MD (1) | MD20130098A2 (enExample) |
| MX (1) | MX2013013905A (enExample) |
| PE (1) | PE20141450A1 (enExample) |
| PH (1) | PH12013502490A1 (enExample) |
| TW (1) | TW201319572A (enExample) |
| UY (1) | UY34115A (enExample) |
| WO (1) | WO2012167181A1 (enExample) |
| ZA (1) | ZA201308812B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030114410A1 (en) | 2000-08-08 | 2003-06-19 | Technion Research And Development Foundation Ltd. | Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis |
| CN110372795A (zh) | 2007-08-02 | 2019-10-25 | 吉利德生物制剂公司 | Lox和loxl2抑制剂及其应用 |
| WO2010080769A2 (en) | 2009-01-06 | 2010-07-15 | Arresto Biosciences, Inc. | Chemotherapeutic methods and compositions |
| RU2012110585A (ru) | 2009-08-21 | 2013-09-27 | Джилид Байолоджикс, Инк. | Каталичические домены лизилоксидазы и loxl2 |
| RU2015108348A (ru) | 2010-02-04 | 2015-07-20 | Джилид Байолоджикс, Инк. | Антитела, связывающиеся с лизилоксидазоподобным ферментом-2 (loxl2), и способы их применения |
| SG11201503065PA (en) * | 2012-10-30 | 2015-05-28 | Gilead Sciences Inc | Therapeutic and diagnostic methods related to lysyl oxidase-like 2 (loxl2) |
| US20150342943A1 (en) | 2014-06-03 | 2015-12-03 | Gilead Sciences, Inc. | Methods of treating liver disease |
| SG11201609522TA (en) * | 2014-06-11 | 2016-12-29 | Gilead Sciences Inc | Methods for treating cardiovascular diseases |
| MA41252A (fr) | 2014-12-23 | 2017-10-31 | Gilead Sciences Inc | Formes solides d'un inhibiteur d'ask 1 |
| CA3016081A1 (en) | 2016-03-04 | 2017-09-08 | Gilead Sciences, Inc. | Compositions and combinations of autotaxin inhibitors |
| JP2019513737A (ja) | 2016-04-08 | 2019-05-30 | ギリアード サイエンシーズ， インコーポレイテッド | がん、炎症性疾患および自己免疫疾患を処置するための組成物および方法 |
| GB201704206D0 (en) | 2017-03-16 | 2017-05-03 | Nordic Bioscience As | Lysyl oxidase like-2 assay |
| WO2023091479A1 (en) * | 2021-11-17 | 2023-05-25 | AmMax Bio, Inc. | Detection and treatment of idiopathic pulmonary fibrosis |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6352862B1 (en) * | 1989-02-17 | 2002-03-05 | Unilever Patent Holdings B.V. | Analytical test device for imuno assays and methods of using same |
| FI92882C (fi) * | 1992-12-29 | 1995-01-10 | Medix Biochemica Ab Oy | Kertakäyttöinen testiliuska ja menetelmä sen valmistamiseksi |
| US20030114410A1 (en) * | 2000-08-08 | 2003-06-19 | Technion Research And Development Foundation Ltd. | Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis |
| CN110372795A (zh) * | 2007-08-02 | 2019-10-25 | 吉利德生物制剂公司 | Lox和loxl2抑制剂及其应用 |
| JP2010038735A (ja) * | 2008-08-05 | 2010-02-18 | Terumo Corp | 腹膜機能の評価方法および腹膜機能評価用イムノクロマト試験紙 |
| BR112012008080A2 (pt) * | 2009-08-21 | 2017-07-04 | Gilead Biologics Inc | ensaios de rastreamento in vivo. |
| RU2015108348A (ru) * | 2010-02-04 | 2015-07-20 | Джилид Байолоджикс, Инк. | Антитела, связывающиеся с лизилоксидазоподобным ферментом-2 (loxl2), и способы их применения |
| US9556882B2 (en) * | 2011-05-10 | 2017-01-31 | Borgwarner Inc. | Turbocharger with variable turbine geometry |
-
2012
- 2012-06-01 US US14/122,984 patent/US20140206017A1/en not_active Abandoned
- 2012-06-01 US US13/487,109 patent/US20120309020A1/en not_active Abandoned
- 2012-06-01 MX MX2013013905A patent/MX2013013905A/es not_active Application Discontinuation
- 2012-06-01 WO PCT/US2012/040585 patent/WO2012167181A1/en not_active Ceased
- 2012-06-01 AP AP2013007285A patent/AP2013007285A0/xx unknown
- 2012-06-01 EA EA201391627A patent/EA201391627A1/ru unknown
- 2012-06-01 BR BR112013030682A patent/BR112013030682A2/pt not_active IP Right Cessation
- 2012-06-01 CN CN201280037235.7A patent/CN103946241A/zh active Pending
- 2012-06-01 JP JP2014513770A patent/JP2014523521A/ja not_active Withdrawn
- 2012-06-01 UY UY0001034115A patent/UY34115A/es not_active Application Discontinuation
- 2012-06-01 MD MDA20130098A patent/MD20130098A2/ro not_active Application Discontinuation
- 2012-06-01 PE PE2013002739A patent/PE20141450A1/es not_active Application Discontinuation
- 2012-06-01 TW TW101119847A patent/TW201319572A/zh unknown
- 2012-06-01 KR KR1020137034711A patent/KR20140048156A/ko not_active Withdrawn
- 2012-06-01 CA CA2837534A patent/CA2837534A1/en not_active Abandoned
- 2012-06-01 AU AU2012261883A patent/AU2012261883A1/en not_active Abandoned
- 2012-06-01 EP EP12725601.4A patent/EP2714744A1/en not_active Withdrawn
- 2012-06-01 PH PH1/2013/502490A patent/PH12013502490A1/en unknown
- 2012-06-01 AR ARP120101959A patent/AR086657A1/es unknown
-
2013
- 2013-11-25 ZA ZA2013/08812A patent/ZA201308812B/en unknown
- 2013-11-26 IL IL229631A patent/IL229631A0/en unknown
- 2013-11-29 CL CL2013003445A patent/CL2013003445A1/es unknown
- 2013-12-13 CR CR20130657A patent/CR20130657A/es unknown
- 2013-12-19 EC ECSP13013092 patent/ECSP13013092A/es unknown
- 2013-12-27 CO CO13301122A patent/CO6940375A2/es unknown
- 2013-12-30 MA MA36627A patent/MA35212B1/fr unknown
-
2016
- 2016-06-09 JP JP2016115175A patent/JP2016164578A/ja active Pending
- 2016-10-12 AU AU2016244254A patent/AU2016244254B2/en not_active Ceased
- 2016-12-01 US US15/366,986 patent/US20170269085A1/en not_active Abandoned
-
2017
- 2017-11-16 JP JP2017221000A patent/JP2018049033A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| UY34115A (es) | 2013-01-03 |
| CL2013003445A1 (es) | 2014-07-25 |
| PE20141450A1 (es) | 2014-11-06 |
| KR20140048156A (ko) | 2014-04-23 |
| ZA201308812B (en) | 2014-08-27 |
| US20170269085A1 (en) | 2017-09-21 |
| EP2714744A1 (en) | 2014-04-09 |
| WO2012167181A1 (en) | 2012-12-06 |
| ECSP13013092A (es) | 2014-08-29 |
| MA35212B1 (fr) | 2014-06-02 |
| TW201319572A (zh) | 2013-05-16 |
| CN103946241A (zh) | 2014-07-23 |
| AU2016244254A1 (en) | 2016-11-03 |
| CR20130657A (es) | 2014-05-16 |
| JP2018049033A (ja) | 2018-03-29 |
| MX2013013905A (es) | 2014-05-14 |
| NZ618682A (en) | 2016-04-29 |
| BR112013030682A2 (pt) | 2016-12-06 |
| AU2016244254B2 (en) | 2018-10-18 |
| AP2013007285A0 (en) | 2013-11-30 |
| JP2014523521A (ja) | 2014-09-11 |
| AU2012261883A1 (en) | 2013-05-02 |
| IL229631A0 (en) | 2014-01-30 |
| US20140206017A1 (en) | 2014-07-24 |
| PH12013502490A1 (en) | 2014-01-20 |
| CA2837534A1 (en) | 2012-12-06 |
| MD20130098A2 (ro) | 2014-06-30 |
| CO6940375A2 (es) | 2014-05-09 |
| EA201391627A1 (ru) | 2014-08-29 |
| US20120309020A1 (en) | 2012-12-06 |
| JP2016164578A (ja) | 2016-09-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |