CA2822435C - Modulation of solubility, stability, absorption, metabolism, and pharmacokinetic profile of lipophilic drugs by sterols - Google Patents
Modulation of solubility, stability, absorption, metabolism, and pharmacokinetic profile of lipophilic drugs by sterols Download PDFInfo
- Publication number
- CA2822435C CA2822435C CA2822435A CA2822435A CA2822435C CA 2822435 C CA2822435 C CA 2822435C CA 2822435 A CA2822435 A CA 2822435A CA 2822435 A CA2822435 A CA 2822435A CA 2822435 C CA2822435 C CA 2822435C
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- Prior art keywords
- testosterone
- formulation
- therapeutic agent
- composition
- solubility
- Prior art date
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
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| US29176909P | 2009-12-31 | 2009-12-31 | |
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| PCT/US2010/062649 WO2011082384A2 (en) | 2009-12-31 | 2010-12-31 | Modulation of solubility, stability, absorption, metabolism, and pharmacokinetic profile of lipophilic drugs by sterols |
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| CA2822435A1 CA2822435A1 (en) | 2011-07-07 |
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| CA2822435A Active CA2822435C (en) | 2009-12-31 | 2010-12-31 | Modulation of solubility, stability, absorption, metabolism, and pharmacokinetic profile of lipophilic drugs by sterols |
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| US20030236236A1 (en) * | 1999-06-30 | 2003-12-25 | Feng-Jing Chen | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs |
| RU2623206C2 (ru) | 2005-04-15 | 2017-06-22 | Кларус Терапьютикс, Инк. | Фармацевтические системы доставки для гидрофобных лекарственных средств и композиций, их содержащих |
| US8492369B2 (en) | 2010-04-12 | 2013-07-23 | Clarus Therapeutics Inc | Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same |
| US11304960B2 (en) | 2009-01-08 | 2022-04-19 | Chandrashekar Giliyar | Steroidal compositions |
| EP2682111A1 (en) | 2009-12-31 | 2014-01-08 | Differential Drug Development Associates LLC | Modulation of solubility, stability, absorption, metabolism, and pharmacokinetic profile of lipophilic drugs by sterols |
| US9358241B2 (en) | 2010-11-30 | 2016-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US9034858B2 (en) | 2010-11-30 | 2015-05-19 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US20180153904A1 (en) | 2010-11-30 | 2018-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US20120148675A1 (en) | 2010-12-10 | 2012-06-14 | Basawaraj Chickmath | Testosterone undecanoate compositions |
| JP6368645B2 (ja) | 2011-09-29 | 2018-08-01 | ピーエルエックス オプコ インコーポレーテッド | 胃腸管に沿った医薬の標的化放出のためのｐＨ依存性担体、それによる組成物、ならびにこれらの製造および使用 |
| CA2931086C (en) | 2012-12-20 | 2020-11-03 | Solural Pharma ApS | Solid oral dosage form of testosterone derivative |
| EP2968137B1 (en) | 2013-03-15 | 2021-11-10 | Marius Pharmaceuticals LLC | Emulsion formulations |
| US10201549B2 (en) * | 2013-06-14 | 2019-02-12 | Professional Compounding Centers Of America (Pcca) | Testosterone combined with anastrozole injection solutions |
| ES2981705T3 (es) * | 2013-12-11 | 2024-10-10 | Health Ever Biotech Co Ltd | Composiciones farmacéuticas de carotenoides |
| CA2950670A1 (en) * | 2014-06-17 | 2015-12-23 | Merck Sharp & Dohme B.V. | Stable formulations of testosterone undecanoate |
| DK3157508T3 (da) * | 2014-06-19 | 2021-02-15 | Solural Pharma ApS | Fast oral doseringsform af lipofile forbindelser |
| US20170246187A1 (en) | 2014-08-28 | 2017-08-31 | Lipocine Inc. | (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE |
| WO2016033556A1 (en) | 2014-08-28 | 2016-03-03 | Lipocine Inc. | BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS |
| RU2017111503A (ru) * | 2014-08-29 | 2018-10-05 | Липосин Инк. | КОМПОЗИЦИИ(17-β)-3-ОКСОАНДРОСТ-4-ЕН-17-ИЛ УНДЕКАНОАТА И СПОСОБЫ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЯ |
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| US10576090B2 (en) | 2020-03-03 |
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| JP5847730B2 (ja) | 2016-01-27 |
| US12295961B2 (en) | 2025-05-13 |
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| JP2013516433A (ja) | 2013-05-13 |
| US20200390784A1 (en) | 2020-12-17 |
| EP2682111A1 (en) | 2014-01-08 |
| WO2011082384A2 (en) | 2011-07-07 |
| US10576089B2 (en) | 2020-03-03 |
| EP2519230A2 (en) | 2012-11-07 |
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