CA2796722C - Compositions and methods for selective delivery of oligonucleotide molecules to specific neuron types - Google Patents

Compositions and methods for selective delivery of oligonucleotide molecules to specific neuron types Download PDF

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Publication number
CA2796722C
CA2796722C CA2796722A CA2796722A CA2796722C CA 2796722 C CA2796722 C CA 2796722C CA 2796722 A CA2796722 A CA 2796722A CA 2796722 A CA2796722 A CA 2796722A CA 2796722 C CA2796722 C CA 2796722C
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Prior art keywords
nucleic acid
compositions
methods
oligonucleotide molecules
selective delivery
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CA2796722A
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English (en)
French (fr)
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CA2796722A1 (en
Inventor
Andres Pablo Montefeltro
Gabriel Alvarado Urbina
Analia Bortolozzi Biassoni
Francesc Artigas Perez
Miquel Vila Bover
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Palomo Ltd
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Micure Therapeutics Ltd
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Priority claimed from EP10382087A external-priority patent/EP2380595A1/en
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Publication of CA2796722A1 publication Critical patent/CA2796722A1/en
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    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
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    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
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    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • C12N2310/34—Spatial arrangement of the modifications
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CA2796722A 2010-04-19 2011-04-19 Compositions and methods for selective delivery of oligonucleotide molecules to specific neuron types Active CA2796722C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US32551510P 2010-04-19 2010-04-19
EP10382087.4 2010-04-19
US61/325,515 2010-04-19
EP10382087A EP2380595A1 (en) 2010-04-19 2010-04-19 Compositions and methods for selective delivery of oligonucleotide molecules to specific neuron types
EP11382031 2011-02-09
EP11382031.0 2011-02-09
PCT/EP2011/056270 WO2011131693A2 (en) 2010-04-19 2011-04-19 Compositions and methods for selective delivery of oligonucleotide molecules to specific neuron types

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CA2796722A1 (en) 2011-10-27
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