LT2560687T - Kompozicijos ir būdai, skirti selektyviam oligonukleotido molekulių pristatymui specifiniams neuronų tipams - Google Patents

Kompozicijos ir būdai, skirti selektyviam oligonukleotido molekulių pristatymui specifiniams neuronų tipams

Info

Publication number
LT2560687T
LT2560687T LTEP11718678.3T LT11718678T LT2560687T LT 2560687 T LT2560687 T LT 2560687T LT 11718678 T LT11718678 T LT 11718678T LT 2560687 T LT2560687 T LT 2560687T
Authority
LT
Lithuania
Prior art keywords
compositions
methods
oligonucleotide molecules
selective delivery
specific neuron
Prior art date
Application number
LTEP11718678.3T
Other languages
English (en)
Lithuanian (lt)
Inventor
Andrés Pablo Montefeltro
Gabriel Alvarado Urbina
Analia Bortolozzi Biassoni
Francesc ARTIGAS PÉREZ
Miquel Vila Bover
Original Assignee
Nlife Therapeutics S.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP10382087A external-priority patent/EP2380595A1/en
Application filed by Nlife Therapeutics S.L. filed Critical Nlife Therapeutics S.L.
Publication of LT2560687T publication Critical patent/LT2560687T/lt

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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
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    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
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    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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LTEP11718678.3T 2010-04-19 2011-04-19 Kompozicijos ir būdai, skirti selektyviam oligonukleotido molekulių pristatymui specifiniams neuronų tipams LT2560687T (lt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US32551510P 2010-04-19 2010-04-19
EP10382087A EP2380595A1 (en) 2010-04-19 2010-04-19 Compositions and methods for selective delivery of oligonucleotide molecules to specific neuron types
EP11382031 2011-02-09
PCT/EP2011/056270 WO2011131693A2 (en) 2010-04-19 2011-04-19 Compositions and methods for selective delivery of oligonucleotide molecules to specific neuron types

Publications (1)

Publication Number Publication Date
LT2560687T true LT2560687T (lt) 2017-09-25

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EP3231446A1 (en) 2017-10-18
AR083715A1 (es) 2013-03-20
MX2012012214A (es) 2013-02-07
WO2011131693A3 (en) 2012-02-16
BR112012026471A2 (pt) 2016-11-29
US20160235856A1 (en) 2016-08-18
AU2011244321A1 (en) 2012-11-15
AU2017204529A1 (en) 2017-07-20
JP5819401B2 (ja) 2015-11-24
AU2019203887B2 (en) 2020-01-23
JP2013525330A (ja) 2013-06-20
ES2638309T3 (es) 2017-10-19
CA2796722C (en) 2021-06-01
US9193969B2 (en) 2015-11-24
RU2012149042A (ru) 2014-05-27
EP2560687B1 (en) 2017-05-24
CN103025357A (zh) 2013-04-03
EP3231446B1 (en) 2026-01-07
AU2020202533A1 (en) 2020-05-07
EP2560687A2 (en) 2013-02-27
DK2560687T3 (en) 2017-09-18
WO2011131693A2 (en) 2011-10-27
MX342764B (es) 2016-10-12
AU2020202533B2 (en) 2022-01-20
AU2019203887A1 (en) 2019-07-18
US10071163B2 (en) 2018-09-11
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KR20130103662A (ko) 2013-09-24
US20120322991A1 (en) 2012-12-20

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