LT2560687T - Kompozicijos ir būdai, skirti selektyviam oligonukleotido molekulių pristatymui specifiniams neuronų tipams - Google Patents
Kompozicijos ir būdai, skirti selektyviam oligonukleotido molekulių pristatymui specifiniams neuronų tipamsInfo
- Publication number
- LT2560687T LT2560687T LTEP11718678.3T LT11718678T LT2560687T LT 2560687 T LT2560687 T LT 2560687T LT 11718678 T LT11718678 T LT 11718678T LT 2560687 T LT2560687 T LT 2560687T
- Authority
- LT
- Lithuania
- Prior art keywords
- compositions
- methods
- oligonucleotide molecules
- selective delivery
- specific neuron
- Prior art date
Links
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
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- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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- C12N2310/341—Gapmers, i.e. of the type ===---===
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32551510P | 2010-04-19 | 2010-04-19 | |
| EP10382087A EP2380595A1 (en) | 2010-04-19 | 2010-04-19 | Compositions and methods for selective delivery of oligonucleotide molecules to specific neuron types |
| EP11382031 | 2011-02-09 | ||
| PCT/EP2011/056270 WO2011131693A2 (en) | 2010-04-19 | 2011-04-19 | Compositions and methods for selective delivery of oligonucleotide molecules to specific neuron types |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT2560687T true LT2560687T (lt) | 2017-09-25 |
Family
ID=44063382
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP11718678.3T LT2560687T (lt) | 2010-04-19 | 2011-04-19 | Kompozicijos ir būdai, skirti selektyviam oligonukleotido molekulių pristatymui specifiniams neuronų tipams |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US9193969B2 (enExample) |
| EP (2) | EP3231446A1 (enExample) |
| JP (1) | JP5819401B2 (enExample) |
| KR (1) | KR20130103662A (enExample) |
| AR (1) | AR083715A1 (enExample) |
| AU (4) | AU2011244321A1 (enExample) |
| BR (1) | BR112012026471A2 (enExample) |
| CA (1) | CA2796722C (enExample) |
| DK (1) | DK2560687T3 (enExample) |
| ES (1) | ES2638309T3 (enExample) |
| LT (1) | LT2560687T (enExample) |
| MX (1) | MX342764B (enExample) |
| RU (1) | RU2664452C2 (enExample) |
| WO (1) | WO2011131693A2 (enExample) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| WO2008033285A2 (en) * | 2006-09-15 | 2008-03-20 | The Trustees Of Culumbia University In The City Of New York | Delivery of double-stranded rna into the central nervous system |
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| AU2013336582A1 (en) | 2012-10-26 | 2015-06-11 | Nlife Therapeutics, S.L. | Compositions and methods for selective delivery of oligonucleotide molecules to cell types |
| CA2890112A1 (en) | 2012-10-26 | 2014-05-01 | Nlife Therapeutics, S.L. | Compositions and methods for the treatment of parkinson disease by the selective delivery of oligonucleotide molecules to specific neuron types |
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| EP2560687B1 (en) | 2017-05-24 |
| ES2638309T3 (es) | 2017-10-19 |
| AU2017204529A1 (en) | 2017-07-20 |
| AR083715A1 (es) | 2013-03-20 |
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| WO2011131693A3 (en) | 2012-02-16 |
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| RU2664452C2 (ru) | 2018-08-17 |
| WO2011131693A2 (en) | 2011-10-27 |
| EP3231446A1 (en) | 2017-10-18 |
| KR20130103662A (ko) | 2013-09-24 |
| US20160235856A1 (en) | 2016-08-18 |
| MX2012012214A (es) | 2013-02-07 |
| US20120322991A1 (en) | 2012-12-20 |
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| US9193969B2 (en) | 2015-11-24 |
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| AU2019203887B2 (en) | 2020-01-23 |
| AU2020202533A1 (en) | 2020-05-07 |
| RU2012149042A (ru) | 2014-05-27 |
| EP2560687A2 (en) | 2013-02-27 |
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