CA2795360A1 - Tissue targeting - Google Patents
Tissue targeting Download PDFInfo
- Publication number
- CA2795360A1 CA2795360A1 CA2795360A CA2795360A CA2795360A1 CA 2795360 A1 CA2795360 A1 CA 2795360A1 CA 2795360 A CA2795360 A CA 2795360A CA 2795360 A CA2795360 A CA 2795360A CA 2795360 A1 CA2795360 A1 CA 2795360A1
- Authority
- CA
- Canada
- Prior art keywords
- agent
- activity
- lmwh
- tumor
- inhibitor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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| PCT/US2011/032771 WO2011130697A2 (en) | 2010-04-16 | 2011-04-15 | Tissue targeting |
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| BR (1) | BR112012026542A2 (https=) |
| CA (1) | CA2795360A1 (https=) |
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| CN104142405A (zh) * | 2014-07-31 | 2014-11-12 | 温州市中心医院 | 硼替佐米对k562细胞株中dna甲基转移酶表达的检测方法 |
| CN107802833A (zh) * | 2016-09-09 | 2018-03-16 | 埃提斯生物技术（上海）有限公司 | 赫赛汀、依维莫司和长春瑞滨的药物组合 |
| WO2019222272A1 (en) | 2018-05-14 | 2019-11-21 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| CN113811333B (zh) | 2019-05-14 | 2024-03-12 | 诺维逊生物股份有限公司 | 靶向抗癌核激素受体的化合物 |
| WO2021097046A1 (en) | 2019-11-13 | 2021-05-20 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| KR20230160299A (ko) | 2021-03-23 | 2023-11-23 | 누베이션 바이오 인크. | 항암 핵 호르몬 수용체 표적화 화합물 |
| US12006314B2 (en) | 2021-05-03 | 2024-06-11 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
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| US3118816A (en) | 1962-04-03 | 1964-01-21 | Abbott Lab | N-succinyl heparin and process |
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| CA1136620A (en) | 1979-01-08 | 1982-11-30 | Ulf P.F. Lindahl | Heparin fragments having selective anticoagulation activity |
| FR2538404B1 (https=) | 1982-12-28 | 1985-08-23 | Anic Spa | |
| IT1195497B (it) | 1983-03-08 | 1988-10-19 | Opocrin Spa | Procedimento per la preparazione di frazioni oligosaccaridiche dotate di proprieta' farmacologiche per degradazione chimica di eparina |
| FR2553287B1 (fr) | 1983-10-18 | 1986-09-12 | Choay Sa | Compositions a base de mucopolysaccharides ou d'oligosaccharides, notamment a base de fractions ou fragments d'heparine, appropriees au traitement de desordres de la proliferation cellulaire |
| IT1169888B (it) | 1983-10-25 | 1987-06-03 | Italfarmaco Spa | Glicosaminoglicani modificati dotati di attivita' antitrombotica |
| US4916219A (en) | 1985-03-28 | 1990-04-10 | University Of Iowa Research Foundation | Oligosaccharide heparin fragments as inhibitors of complement cascade |
| US4847338A (en) | 1985-03-28 | 1989-07-11 | University Of Iowa Research Foundation | Low molecular weight heparin fragments as inhibitors of complement activation |
| US4868103A (en) | 1986-02-19 | 1989-09-19 | Enzo Biochem, Inc. | Analyte detection by means of energy transfer |
| US5262403A (en) | 1986-03-10 | 1993-11-16 | Board Of Regents, The University Of Texas System | Glycosaminoglycan derivatives and their use as inhibitors of tumor invasiveness of metastatic profusion-II |
| US5541166A (en) | 1987-01-23 | 1996-07-30 | The Australian National University | Sulphated polysaccharides having anti-metastatic and/or anti-inflammatory activity |
| US5668116A (en) | 1987-03-19 | 1997-09-16 | Anthropharm Pty. Limited | Anti-inflammatory compounds and compositions |
| FR2614026B1 (fr) | 1987-04-16 | 1992-04-17 | Sanofi Sa | Heparines de bas poids moleculaire, a structure reguliere, leur preparation et leurs applications biologiques |
| US5264425A (en) | 1988-06-03 | 1993-11-23 | Italfarmaco S.P.A. | Glycosaminoglycan salts and pharmaceutical compositions containing them |
| IL86753A0 (en) | 1988-06-15 | 1988-11-30 | Hadassah Med Org | Pharmaceutical compositions for treatment of lupus |
| US5308617A (en) | 1988-08-10 | 1994-05-03 | Halzyme Ltd. | Protein heparin conjugates |
| DK191889D0 (da) | 1989-04-20 | 1989-04-20 | Bukh Meditec | Kosmetisk middel |
| SE9002550D0 (sv) | 1990-08-01 | 1990-08-01 | Kabivitrum Ab | Heparinfragment |
| IT1243987B (it) | 1990-10-29 | 1994-06-28 | Derivati Organici Lab | Procedimento per la preparazione di epossi-eparidi prodotti ottenuti ecomposizioni farmaceutiche che li contengono |
| US5250519A (en) | 1991-03-29 | 1993-10-05 | Glycomed Incorporated | Non-anticoagulant heparin derivatives |
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| SE9101155D0 (sv) | 1991-04-18 | 1991-04-18 | Kabi Pharmacia Ab | Novel heparin derivatives |
| IT1254216B (it) | 1992-02-25 | 1995-09-14 | Opocrin Spa | Derivati polisaccaridici di eparina, eparan solfato, loro frazioni e frammenti, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono |
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| IT1264709B1 (it) | 1993-07-12 | 1996-10-04 | Italfarmaco Spa | Derivati eparinici ad attivita' antimetastatica |
| US5583121A (en) | 1994-01-12 | 1996-12-10 | Michigan State University | Non-anticoagulant chemically modified heparinoids for treating hypovolemic shock and related shock syndromes |
| US6127347A (en) | 1994-01-12 | 2000-10-03 | Univ Michigan | Non-anticoagulant chemically modified heparinoids for treating hypovolemic shock and related shock syndromes |
| AU2435795A (en) | 1994-05-06 | 1995-11-29 | Glycomed Incorporated | O-desulfated heparin derivatives, methods of making and uses thereof |
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2011
- 2011-04-15 BR BR112012026542A patent/BR112012026542A2/pt not_active Application Discontinuation
- 2011-04-15 CN CN201180019382.7A patent/CN102985443B/zh not_active Expired - Fee Related
- 2011-04-15 CA CA2795360A patent/CA2795360A1/en not_active Abandoned
- 2011-04-15 EP EP11769718.5A patent/EP2558506B1/en active Active
- 2011-04-15 US US13/641,278 patent/US9387256B2/en active Active
- 2011-04-15 JP JP2013505200A patent/JP5982361B2/ja active Active
- 2011-04-15 WO PCT/US2011/032771 patent/WO2011130697A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011130697A3 (en) | 2012-01-26 |
| BR112012026542A2 (pt) | 2016-07-12 |
| EP2558506A4 (en) | 2013-08-14 |
| JP5982361B2 (ja) | 2016-08-31 |
| CN102985443B (zh) | 2017-05-10 |
| EP2558506B1 (en) | 2019-06-26 |
| US9387256B2 (en) | 2016-07-12 |
| JP2013527158A (ja) | 2013-06-27 |
| CN102985443A (zh) | 2013-03-20 |
| US20130156698A1 (en) | 2013-06-20 |
| WO2011130697A2 (en) | 2011-10-20 |
| EP2558506A2 (en) | 2013-02-20 |
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| FZDE | Discontinued |
Effective date: 20180717 |