CA2789114C - Medical compositions for intravesical treatment of bladder cancer - Google Patents

Medical compositions for intravesical treatment of bladder cancer Download PDF

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Publication number
CA2789114C
CA2789114C CA2789114A CA2789114A CA2789114C CA 2789114 C CA2789114 C CA 2789114C CA 2789114 A CA2789114 A CA 2789114A CA 2789114 A CA2789114 A CA 2789114A CA 2789114 C CA2789114 C CA 2789114C
Authority
CA
Canada
Prior art keywords
bladder
activity
phe
cells
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2789114A
Other languages
English (en)
French (fr)
Other versions
CA2789114A1 (en
Inventor
Bastiaan Nuijen
Ernie Pfadenhauer
Jos H. Beijnen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spectrum Pharmaceuticals Inc
Original Assignee
Spectrum Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spectrum Pharmaceuticals Inc filed Critical Spectrum Pharmaceuticals Inc
Publication of CA2789114A1 publication Critical patent/CA2789114A1/en
Application granted granted Critical
Publication of CA2789114C publication Critical patent/CA2789114C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA2789114A 2001-11-01 2002-11-01 Medical compositions for intravesical treatment of bladder cancer Expired - Fee Related CA2789114C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34444601P 2001-11-01 2001-11-01
US60/344,446 2001-11-01
CA2466148A CA2466148C (en) 2001-11-01 2002-11-01 Medical compositions for intravesical treatment of bladder cancer

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2466148A Division CA2466148C (en) 2001-11-01 2002-11-01 Medical compositions for intravesical treatment of bladder cancer

Publications (2)

Publication Number Publication Date
CA2789114A1 CA2789114A1 (en) 2003-05-08
CA2789114C true CA2789114C (en) 2014-03-25

Family

ID=23350584

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2789114A Expired - Fee Related CA2789114C (en) 2001-11-01 2002-11-01 Medical compositions for intravesical treatment of bladder cancer
CA2466148A Expired - Fee Related CA2466148C (en) 2001-11-01 2002-11-01 Medical compositions for intravesical treatment of bladder cancer

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2466148A Expired - Fee Related CA2466148C (en) 2001-11-01 2002-11-01 Medical compositions for intravesical treatment of bladder cancer

Country Status (12)

Country Link
US (6) US6894071B2 (https=)
EP (3) EP1439835A2 (https=)
JP (1) JP4317452B2 (https=)
AT (2) ATE455545T1 (https=)
AU (1) AU2002350115A1 (https=)
CA (2) CA2789114C (https=)
CY (1) CY1111252T1 (https=)
DE (2) DE60235214D1 (https=)
DK (2) DK2060259T3 (https=)
ES (2) ES2384208T3 (https=)
PT (2) PT2060259E (https=)
WO (1) WO2003037314A2 (https=)

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AU2002350115A1 (en) 2001-11-01 2003-05-12 Spectrum Pharmaceuticals, Inc. Medical compositions for intravesical treatment of bladder cancer
US8563592B2 (en) * 2001-11-01 2013-10-22 Spectrum Pharmaceuticals, Inc. Bladder cancer treatment and methods
US8361490B2 (en) * 2004-09-16 2013-01-29 Theracoat Ltd. Biocompatible drug delivery apparatus and methods
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RU2396953C2 (ru) * 2006-02-09 2010-08-20 Спектрум Фармасьютикалз, Инк. Лечение рака мочевого пузыря с использованием ео9 и пропиленгликоля
WO2008147445A2 (en) * 2006-11-09 2008-12-04 University Of Maryland, Baltimore Use of 5,6-dimethylxanthenone-4-acetic acid as an antimicrobial agent
AU2008224962B2 (en) * 2007-03-13 2013-07-25 Spectrum Pharmaceuticals, Inc. Intravesical apaziquone administration following transurethral resection for treating cancer
RU2354386C1 (ru) * 2007-12-26 2009-05-10 ГУ Московская городская онкологическая больница №62 Департамента здравоохранения г. Москвы Способ профилактики рецидивов поверхностного рака мочевого пузыря
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CN104743887B (zh) * 2014-09-22 2016-03-23 巨石集团有限公司 一种玻璃纤维组合物及其玻璃纤维和复合材料
RU2019112740A (ru) 2016-09-30 2020-11-02 АСАНА БАЙОСАЙЕНСИЗ, ЭлЭлСи P2x3 и/или p2x2/3 соединения и способы
EP3924521A4 (en) 2019-02-15 2023-03-29 IncellDx, Inc. BLADDER-ASSOCIATED SAMPLES TESTING, IDENTIFICATION AND TREATMENT OF BLADDER-ASSOCIATED NEOPLASIA, AND KITS FOR USE THEREON
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Also Published As

Publication number Publication date
EP1864660A3 (en) 2008-04-23
AU2002350115A1 (en) 2003-05-12
EP1864660B1 (en) 2010-12-29
EP1864660A2 (en) 2007-12-12
DE60238798D1 (de) 2011-02-10
PT1864660E (pt) 2011-03-31
US20080166402A1 (en) 2008-07-10
ES2384208T3 (es) 2012-07-02
WO2003037314A2 (en) 2003-05-08
DK2060259T3 (da) 2010-05-17
US20070010570A1 (en) 2007-01-11
US20030133954A1 (en) 2003-07-17
EP1439835A2 (en) 2004-07-28
EP2060259A1 (en) 2009-05-20
DK1864660T3 (da) 2011-02-21
US20090076123A1 (en) 2009-03-19
US7977369B2 (en) 2011-07-12
DE60235214D1 (de) 2010-03-11
CA2789114A1 (en) 2003-05-08
ATE493126T1 (de) 2011-01-15
CY1111252T1 (el) 2015-08-05
JP4317452B2 (ja) 2009-08-19
WO2003037314A3 (en) 2003-10-16
US20050215615A1 (en) 2005-09-29
ES2341922T3 (es) 2010-06-29
JP2005532986A (ja) 2005-11-04
US20120252861A1 (en) 2012-10-04
EP2060259B1 (en) 2010-01-20
CA2466148A1 (en) 2003-05-08
ATE455545T1 (de) 2010-02-15
US6894071B2 (en) 2005-05-17
US8648108B2 (en) 2014-02-11
PT2060259E (pt) 2010-04-26
CA2466148C (en) 2013-01-08
HK1132181A1 (en) 2010-02-19

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