AU2002350115A1 - Medical compositions for intravesical treatment of bladder cancer - Google Patents

Medical compositions for intravesical treatment of bladder cancer

Info

Publication number
AU2002350115A1
AU2002350115A1 AU2002350115A AU2002350115A AU2002350115A1 AU 2002350115 A1 AU2002350115 A1 AU 2002350115A1 AU 2002350115 A AU2002350115 A AU 2002350115A AU 2002350115 A AU2002350115 A AU 2002350115A AU 2002350115 A1 AU2002350115 A1 AU 2002350115A1
Authority
AU
Australia
Prior art keywords
formulation
bladder cancer
medical compositions
intravesical treatment
azaridinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002350115A
Other languages
English (en)
Inventor
Jos F. Beijen
Bastiaan Nuijen
Ernie Pfadenhauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spectrum Pharmaceuticals Inc
Original Assignee
Spectrum Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spectrum Pharmaceuticals Inc filed Critical Spectrum Pharmaceuticals Inc
Publication of AU2002350115A1 publication Critical patent/AU2002350115A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2002350115A 2001-11-01 2002-11-01 Medical compositions for intravesical treatment of bladder cancer Abandoned AU2002350115A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34444601P 2001-11-01 2001-11-01
US60/344,446 2001-11-01
PCT/US2002/035191 WO2003037314A2 (en) 2001-11-01 2002-11-01 Medical compositions for intravesical treatment of bladder cancer

Publications (1)

Publication Number Publication Date
AU2002350115A1 true AU2002350115A1 (en) 2003-05-12

Family

ID=23350584

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002350115A Abandoned AU2002350115A1 (en) 2001-11-01 2002-11-01 Medical compositions for intravesical treatment of bladder cancer

Country Status (12)

Country Link
US (6) US6894071B2 (https=)
EP (3) EP1439835A2 (https=)
JP (1) JP4317452B2 (https=)
AT (2) ATE455545T1 (https=)
AU (1) AU2002350115A1 (https=)
CA (2) CA2789114C (https=)
CY (1) CY1111252T1 (https=)
DE (2) DE60235214D1 (https=)
DK (2) DK2060259T3 (https=)
ES (2) ES2384208T3 (https=)
PT (2) PT2060259E (https=)
WO (1) WO2003037314A2 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002350115A1 (en) 2001-11-01 2003-05-12 Spectrum Pharmaceuticals, Inc. Medical compositions for intravesical treatment of bladder cancer
US8563592B2 (en) * 2001-11-01 2013-10-22 Spectrum Pharmaceuticals, Inc. Bladder cancer treatment and methods
US8361490B2 (en) * 2004-09-16 2013-01-29 Theracoat Ltd. Biocompatible drug delivery apparatus and methods
AU2006230582A1 (en) * 2005-03-31 2006-10-05 Spectrum Pharmaceuticals, Inc. Indoloquinone tumor radiation sensitization
WO2006130978A1 (en) 2005-06-06 2006-12-14 The University Of British Columbia Polymer-based serum albumin substitute
RU2396953C2 (ru) * 2006-02-09 2010-08-20 Спектрум Фармасьютикалз, Инк. Лечение рака мочевого пузыря с использованием ео9 и пропиленгликоля
WO2008147445A2 (en) * 2006-11-09 2008-12-04 University Of Maryland, Baltimore Use of 5,6-dimethylxanthenone-4-acetic acid as an antimicrobial agent
AU2008224962B2 (en) * 2007-03-13 2013-07-25 Spectrum Pharmaceuticals, Inc. Intravesical apaziquone administration following transurethral resection for treating cancer
RU2354386C1 (ru) * 2007-12-26 2009-05-10 ГУ Московская городская онкологическая больница №62 Департамента здравоохранения г. Москвы Способ профилактики рецидивов поверхностного рака мочевого пузыря
GB0800311D0 (en) * 2008-01-09 2008-02-20 Cytosystems Ltd Apparatus and method for filtering biological material
WO2011089604A2 (en) 2010-01-20 2011-07-28 Theracoat Ltd Material and method for treating internal cavities
BR112012021991A2 (pt) 2010-03-01 2020-09-01 The University Of British Columbia policlicerol hiperramificado uso de um poliglicerol hipermanificado, método de adiministração de uma força biologicamente ativa a um tecido biológico, composição farmacêutica e método de síntese de um poliglicerol hiperrramificado.
WO2012040492A1 (en) * 2010-09-22 2012-03-29 The Board Of Regents Of The University Of Texas System Methods of treating cancer comprising targeting nqo1
WO2013011504A1 (en) 2011-07-20 2013-01-24 Theracoat Ltd. Materials and method for treating internal body cavities
JP6495654B2 (ja) 2011-10-24 2019-04-03 アサナ バイオサイエンシズ，リミティド ライアビリティ カンパニー シクロヘキシルアミン類
WO2014062856A1 (en) 2012-10-16 2014-04-24 Halozyme, Inc. Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods
CA2933811C (en) 2013-12-16 2021-02-09 Asana Biosciences, Llc P2x3 and/or p2x2/3 compounds and methods
CN104743887B (zh) * 2014-09-22 2016-03-23 巨石集团有限公司 一种玻璃纤维组合物及其玻璃纤维和复合材料
RU2019112740A (ru) 2016-09-30 2020-11-02 АСАНА БАЙОСАЙЕНСИЗ, ЭлЭлСи P2x3 и/или p2x2/3 соединения и способы
EP3924521A4 (en) 2019-02-15 2023-03-29 IncellDx, Inc. BLADDER-ASSOCIATED SAMPLES TESTING, IDENTIFICATION AND TREATMENT OF BLADDER-ASSOCIATED NEOPLASIA, AND KITS FOR USE THEREON
CN112220742A (zh) * 2019-07-15 2021-01-15 深圳艾欣达伟医药科技有限公司 稳定的ast-3424注射液制剂及制备方法

Family Cites Families (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993754A (en) * 1974-10-09 1976-11-23 The United States Of America As Represented By The United States Energy Research And Development Administration Liposome-encapsulated actinomycin for cancer chemotherapy
JPS54151134A (en) 1978-05-19 1979-11-28 Kureha Chem Ind Co Ltd Antitumorigenic agent
NL8001280A (nl) * 1980-03-04 1981-10-01 Philips Nv Lagedrukontladingslamp.
EP0163696B1 (en) 1983-11-14 1992-11-25 Columbia Laboratories, Inc. Use of a bioadhesive
US4898729A (en) 1983-12-09 1990-02-06 Euroceltique, S.A. Treatment of hypertension, compounds and compositions for antihypertension and diuresis
US4671954A (en) * 1983-12-13 1987-06-09 University Of Florida Microspheres for incorporation of therapeutic substances and methods of preparation thereof
JPS60163621A (ja) 1984-02-02 1985-08-26 村上　俊文 紙製便座カバ−の製造方法
JPS60163821A (ja) 1984-02-03 1985-08-26 Tdk Corp フエライト粒子を含む薬剤用担体
JPS61189215A (ja) 1985-02-18 1986-08-22 Teijin Ltd ５−フルオロ−２′−デオキシウリジンエステル類の油状医薬組成物
EP0302874B1 (en) * 1986-04-17 1992-12-02 SPECKAMP, Willem Nico Indoloquinone compounds
US4871542A (en) * 1987-04-30 1989-10-03 Ferring Service Center, N.V. Method and apparatus useful for delivering medicinal compositions into the bladder and urinary tract
EP0331635A3 (en) 1988-02-29 1990-02-28 The Board of Regents of the University of Texas System Preparations for treating bladder cancer
EP0338679A3 (en) 1988-03-24 1991-03-06 Genentech, Inc. Tumour necrosis factor in the treatment of bladder cancer
FR2629584B1 (fr) 1988-03-31 1993-06-04 France Etat Armement Dispositif de stabilisation pour un projectile a faible moment d'inertie longitudinal tire a partir d'un tube raye
US5843156A (en) * 1988-08-24 1998-12-01 Endoluminal Therapeutics, Inc. Local polymeric gel cellular therapy
US5744166A (en) * 1989-02-25 1998-04-28 Danbiosyst Uk Limited Drug delivery compositions
PT93772A (pt) 1989-04-17 1991-01-08 Searle & Co Processo para a preparacao de composicoes para o tratamento de neoplasias, contendo um agente anti-neoplastico, por exemplo doxorubicina e um agente protector para reduzir os efeitos secundarios, por exemplo carbetimer
US5216011A (en) * 1989-09-01 1993-06-01 Bristol-Myers Squibb Co. Stable solutions of mitomycin c
FI84874C (fi) 1989-11-02 1992-02-10 Valio Meijerien Foerfarande foer inkapsling av biologiskt aktiva aemnen, enligt metoden framstaelld kapsel, dess anvaendning och foder innehaollande den.
US5237466A (en) 1989-11-02 1993-08-17 International Business Machines Corporation Method and apparatus for programmably controlling spindle synchronization and phase among disk drives in a storage subsystem
US5292516A (en) * 1990-05-01 1994-03-08 Mediventures, Inc. Body cavity drug delivery with thermoreversible gels containing polyoxyalkylene copolymers
US5346703A (en) * 1990-08-07 1994-09-13 Mediventures, Inc. Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels
IT1250421B (it) 1991-05-30 1995-04-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato con proprieta' bio-adesive.
US5550110A (en) 1992-04-22 1996-08-27 Warner-Lambert Company Endothelin Antagonists II
JP3598049B2 (ja) 1992-09-18 2004-12-08 山之内製薬株式会社 ハイドロゲル徐放性製剤
US5744155A (en) * 1993-08-13 1998-04-28 Friedman; Doron Bioadhesive emulsion preparations for enhanced drug delivery
EP0642797B1 (en) 1993-09-09 2000-05-17 Takeda Chemical Industries, Ltd. Formulation comprising antibacterial substance and antiulcer substance
CA2135151A1 (en) 1993-11-08 1995-05-09 Mitsuhiro Wakimasu Cyclic hexapeptides, their production and use
US5405622A (en) * 1993-12-22 1995-04-11 Vernice; Joseph Gamma radiation resistant lubricating gel
TW438601B (en) * 1994-05-18 2001-06-07 Janssen Pharmaceutica Nv New mucoadhesive emulsion compositions and a process for the preparation thereof
US5811416A (en) 1994-06-06 1998-09-22 Board Of Regents The University Of Texas System Endothelin antagonist and/or endothelin synthase inhibitor in combination with a progestin, an estrogen, a cyclooxygenase inhibitor, or a nitric acid donor or substrate
US5612359A (en) 1994-08-26 1997-03-18 Bristol-Myers Squibb Company Substituted biphenyl isoxazole sulfonamides
WO1996019233A2 (en) 1994-12-12 1996-06-27 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain, inflammation and spasm
US5749845A (en) * 1995-01-25 1998-05-12 Iotek, Inc. Delivering an agent to an organ
WO1997023456A1 (en) 1995-12-21 1997-07-03 British Technology Group Ltd. Indoloquinone derivatives as bioreductive agents
US5985312A (en) 1996-01-26 1999-11-16 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers
JP2000509014A (ja) * 1996-03-11 2000-07-18 フォーカル，インコーポレイテッド 放射性核種および放射性医薬品のポリマー送達
US5955096A (en) * 1996-06-25 1999-09-21 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients
US6251861B1 (en) 1996-06-27 2001-06-26 Takeda Chemical Industries, Ltd. Treatment of cerebral infarction using cyclic hexapeptides
JP2967734B2 (ja) * 1996-10-18 1999-10-25 日本電気株式会社 薄膜の形成方法
KR20010006027A (ko) * 1997-04-03 2001-01-15 포인트 바이오메디칼 코퍼레이션 방광내 약물 송달 시스템
US5854382A (en) * 1997-08-18 1998-12-29 Meadox Medicals, Inc. Bioresorbable compositions for implantable prostheses
AU9082698A (en) * 1997-09-08 1999-03-29 Theramark Limited Treatment of inflammatory conditions
US6156744A (en) 1998-03-19 2000-12-05 Cancer Research Campaign Tech (London) DT-diaphorase directed anti-tumor agents
CA2268640A1 (en) 1998-04-14 1999-10-14 Mitsuru Shiraishi Composition for preventing or treating ischemic disease
US6171610B1 (en) * 1998-04-24 2001-01-09 University Of Massachusetts Guided development and support of hydrogel-cell compositions
WO1999065483A1 (en) 1998-05-05 1999-12-23 Astrazeneca Ab Mycobacterial inhibitors
IL124957A0 (en) 1998-06-16 1999-01-26 Univ Ben Gurion Active ingredient delivery systems and devices based on porous matrices
US6087396A (en) * 1998-10-05 2000-07-11 Situs Corporation Oxybutynin formulations and method of use
GB9827034D0 (en) 1998-12-10 1999-02-03 Univ Manchester Delivery formulation
JP2000256182A (ja) 1999-03-03 2000-09-19 Kazuhiro Morimoto 抗菌製剤
EP1177439B1 (en) 1999-04-29 2004-09-08 Coley Pharmaceutical GmbH Screening for immunostimulatory dna functional modifiers
US7566452B1 (en) 1999-05-04 2009-07-28 New York University Cancer treatment with endothelin receptor antagonists
US6545048B1 (en) 1999-06-29 2003-04-08 California Institute Of Technology Compositions and methods of treating cancer using compositions comprising an inhibitor or endothelin receptor activity
JP2003535061A (ja) 2000-05-31 2003-11-25 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー エンドセリン受容体拮抗剤および疼痛軽減特性を有する抗癲癇化合物または鎮痛剤の複合物
JP4323802B2 (ja) 2000-12-01 2009-09-02 エムジーアイ・ジーピー・インコーポレーテッド 化合物およびその使用
WO2002049630A2 (en) 2000-12-21 2002-06-27 Bristol-Myers Squibb Company Method for preventing or treating pain by administering an endothelin antagonist
WO2003009805A2 (en) 2001-07-23 2003-02-06 Brigham And Women's Hospital, Inc. Analgesic methods using endothelin receptor ligands
AU2002350115A1 (en) 2001-11-01 2003-05-12 Spectrum Pharmaceuticals, Inc. Medical compositions for intravesical treatment of bladder cancer
US7973064B2 (en) 2001-11-27 2011-07-05 The Board Of Trustees Of The University Of Illinois Method and composition for potentiating an opiate analgesic
WO2003092731A1 (en) 2002-05-03 2003-11-13 Novo Nordisk A/S Stabilised solid compositions of modified factor vii
US20040009918A1 (en) 2002-05-03 2004-01-15 Hanne Nedergaard Stabilised solid compositions of modified factor VII
CA2502848C (en) 2002-10-24 2012-10-02 The Board Of Trustees Of The University Of Illinois Use of irl-1620 and paclitaxel for preventing and treating breast tumors
RU2423381C2 (ru) 2005-07-25 2011-07-10 Трабьон Фармасьютикалз, Инк. Снижение количества в-клеток с использованием cd37-специфических и cd20-специфических связывающих молекул
RU2396953C2 (ru) 2006-02-09 2010-08-20 Спектрум Фармасьютикалз, Инк. Лечение рака мочевого пузыря с использованием ео9 и пропиленгликоля

Also Published As

Publication number Publication date
EP1864660A3 (en) 2008-04-23
EP1864660B1 (en) 2010-12-29
EP1864660A2 (en) 2007-12-12
DE60238798D1 (de) 2011-02-10
PT1864660E (pt) 2011-03-31
US20080166402A1 (en) 2008-07-10
ES2384208T3 (es) 2012-07-02
WO2003037314A2 (en) 2003-05-08
DK2060259T3 (da) 2010-05-17
US20070010570A1 (en) 2007-01-11
US20030133954A1 (en) 2003-07-17
EP1439835A2 (en) 2004-07-28
EP2060259A1 (en) 2009-05-20
DK1864660T3 (da) 2011-02-21
CA2789114C (en) 2014-03-25
US20090076123A1 (en) 2009-03-19
US7977369B2 (en) 2011-07-12
DE60235214D1 (de) 2010-03-11
CA2789114A1 (en) 2003-05-08
ATE493126T1 (de) 2011-01-15
CY1111252T1 (el) 2015-08-05
JP4317452B2 (ja) 2009-08-19
WO2003037314A3 (en) 2003-10-16
US20050215615A1 (en) 2005-09-29
ES2341922T3 (es) 2010-06-29
JP2005532986A (ja) 2005-11-04
US20120252861A1 (en) 2012-10-04
EP2060259B1 (en) 2010-01-20
CA2466148A1 (en) 2003-05-08
ATE455545T1 (de) 2010-02-15
US6894071B2 (en) 2005-05-17
US8648108B2 (en) 2014-02-11
PT2060259E (pt) 2010-04-26
CA2466148C (en) 2013-01-08
HK1132181A1 (en) 2010-02-19

Similar Documents

Publication Publication Date Title
AU2002350115A1 (en) Medical compositions for intravesical treatment of bladder cancer
WO2003096990A3 (en) Protein cages for the delivery of medical imaging and therapy
EP2767291A3 (en) Treatment of glycogen storage disease type II
EP1810715A3 (en) Combination comprising an agent decreasing VEGF activity and an agent decreasing EGF activity
WO2002056912A3 (en) Pharmaceutical combination for the treatment of cancer containing a 4-quinazolineamine and another anti-neoplastic agent
WO2001052847A8 (en) Thiazole, imidazole and oxazole compounds and treatments of disorders associated with protein aging
WO2003022852A3 (en) Furo-and thienopyrimidine derivatives as angiogenesis inhibitors
WO2003041686A3 (en) Improved therapy for topical diseases
AU6549898A (en) Method for the broad based treatment of infections, especially infections of organs such as the skin and vagina
CA2385130A1 (en) Novel spiroheterocyclic compounds useful as reversible inhibitors of cysteine proteases
WO2006034315A3 (en) Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes
WO2001092288A3 (en) Cobalamin compounds useful as antibiotic agents and as imaging agents
AU1223199A (en) Pharmaceutical formulation for stimulating the growth of gram-positive bacilli and increasing the acidity in vagina and the use thereof
WO2002076472A3 (en) Pharmaceutical combinations for the treatment of cancer comprising dioxolane nucleoside analogs
EP1830191A3 (en) Pharmaceutical preparations containing thiazolidinediones for the treatment of endocrine autoimmune diseases
EP1264603B8 (en) Use of L-polynucleotides for in vivo imaging
AU2002315131A1 (en) Aminediols as agents for the treatment of alzheimer's disease
WO2001024783A3 (de) Verwendung von (+)-tramadol, o-demethyltramadol bzw. (+)-o-demethyltramadol, o-desmethyl-n-mono-desmethyl-tramadol bzw. (+)-o-desmethyl-n-mono-desmethyl-tramadol zur therapie der harninkontinenz
AU2001259507A1 (en) Compounds and methods for the diagnosis and treatment of ehrlichia infection
WO2003022203A3 (en) Products and methods for treating microbial infections
TW200509970A (en) External skin treatment composition
WO1997032593A3 (en) Composition containing iso-flavonoids and lignans
WO2003076445A3 (en) Microtubule stabilizing compounds
WO2004037167A3 (en) Methods of treating dry eye disease with lantibiotics
EP1072595A3 (en) 4-arylpiperidine derivatives for the treatment of pruritus

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase