CA2785592A1 - Determination of exosomel biomarkers for predicting cardiovascular events - Google Patents
Determination of exosomel biomarkers for predicting cardiovascular events Download PDFInfo
- Publication number
- CA2785592A1 CA2785592A1 CA2785592A CA2785592A CA2785592A1 CA 2785592 A1 CA2785592 A1 CA 2785592A1 CA 2785592 A CA2785592 A CA 2785592A CA 2785592 A CA2785592 A CA 2785592A CA 2785592 A1 CA2785592 A1 CA 2785592A1
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- biomarker
- proteins
- risk
- exosomes
- cardiovascular event
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
- G01N2333/8121—Serpins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- G01N2333/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10150340.7 | 2010-01-08 | ||
| EP10150340 | 2010-01-08 | ||
| PCT/EP2011/050171 WO2011083145A1 (en) | 2010-01-08 | 2011-01-07 | Determination of exosomel biomarkers for predicting cardiovascular events |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2785592A1 true CA2785592A1 (en) | 2011-07-14 |
Family
ID=43533349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2785592A Abandoned CA2785592A1 (en) | 2010-01-08 | 2011-01-07 | Determination of exosomel biomarkers for predicting cardiovascular events |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20120309041A1 (https=) |
| EP (1) | EP2521918B1 (https=) |
| JP (1) | JP5732474B2 (https=) |
| CN (1) | CN102812362B (https=) |
| AU (1) | AU2011204625B2 (https=) |
| CA (1) | CA2785592A1 (https=) |
| DK (1) | DK2521918T3 (https=) |
| SG (1) | SG181963A1 (https=) |
| WO (1) | WO2011083145A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114150057A (zh) * | 2021-12-21 | 2022-03-08 | 贾龙飞 | 一种诊断阿尔茨海默病的外泌体蛋白及其用途 |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012304635B2 (en) * | 2011-09-06 | 2017-08-31 | Translational Sciences Inc. | SerpinF2-binding molecules and methods of use |
| TWI420106B (zh) * | 2011-12-01 | 2013-12-21 | Univ Kaohsiung Medical | Soluble CD14 as a biomarker for detection of coronary artery disease |
| WO2013120995A1 (en) | 2012-02-17 | 2013-08-22 | Cavadis B.V. | Exosomal biomarker for cardiovascular events in females |
| CN103376313A (zh) * | 2012-04-12 | 2013-10-30 | 梁春 | 一种基于血清外来体检测急性冠脉综合征的液相芯片试剂盒及其制备方法 |
| WO2014059336A1 (en) | 2012-10-12 | 2014-04-17 | University Of Notre Dame Du Lac | Exosomes and diagnostic biomarkers |
| CA2893639C (en) * | 2012-12-04 | 2021-01-05 | F. Hoffmann-La Roche Ag | Biomarkers in the selection of therapy of heart failure |
| WO2014159662A1 (en) | 2013-03-13 | 2014-10-02 | University Of Miami | Method for isolation and purification of microvesicles from cell culture supernatants and biological fluids |
| US12558316B2 (en) | 2013-03-13 | 2026-02-24 | University Of Miami | Methods and compositions for the treatment of epidermolysis bullosa |
| JP6547625B2 (ja) | 2013-10-25 | 2019-07-24 | 凸版印刷株式会社 | 膜小胞回収デバイス、膜小胞回収方法、及び膜小胞分析方法 |
| CN106573220B (zh) | 2014-07-24 | 2019-08-16 | 凸版印刷株式会社 | 脂质膜结构体、脂质膜结构体固定化载体、及胞体的融合方法 |
| WO2016048388A1 (en) | 2014-09-26 | 2016-03-31 | Somalogic, Inc. | Cardiovascular risk event prediction and uses thereof |
| WO2016140388A1 (ko) * | 2015-03-05 | 2016-09-09 | 경북대학교 산학협력단 | 엑소좀 또는 이의 단백질을 포함하는 장기 독성 진단용 바이오마커 조성물 및 이를 이용한 진단 방법 |
| ES2957217T3 (es) * | 2015-12-08 | 2024-01-15 | Umc Utrecht Holding Bv | Marcadores de vesículas extracelulares para angina estable y angina inestable |
| WO2020004436A1 (ja) * | 2018-06-27 | 2020-01-02 | 日立化成ダイアグノスティックス・システムズ株式会社 | 試料中のエクソソームの破壊方法及び破壊用試薬 |
| CN109055489A (zh) * | 2018-08-25 | 2018-12-21 | 上海浦美医学科技有限公司 | 一种基于细胞外囊泡dna检测egfr-tki敏感突变的方法 |
| CN113970640B (zh) * | 2020-07-24 | 2022-07-08 | 首都医科大学附属北京天坛医院 | 用于ich预后评估的生物标记物及其应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60031512T2 (de) * | 1999-02-19 | 2007-08-23 | University Of Iowa Research Foundation | Diagnostika und therapeutika für maculare degeneration |
| CA2384295A1 (en) * | 1999-04-28 | 2000-11-02 | Yahia Gawad | Method for determining plasminogen activator inhibitor |
| US7972802B2 (en) * | 2005-10-31 | 2011-07-05 | University Of Washington | Lipoprotein-associated markers for cardiovascular disease |
| CN101371144A (zh) * | 2006-01-25 | 2009-02-18 | 霍夫曼-拉罗奇有限公司 | 抗肌钙蛋白抗体和心血管风险 |
| JP5357746B2 (ja) * | 2006-03-11 | 2013-12-04 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 末梢性の動脈疾患のためのバイオマーカーとしてのβ−２ミクログロブリン |
| DE102006050497A1 (de) * | 2006-10-26 | 2008-04-30 | Brahms Aktiengesellschaft | Risikostratifizierung des akuten Koronarsyndroms mittels Fragmenten / Teilpeptiden des proVasopressins, insbesondere Copeptin oder Neurophysin II |
| DE102006058266A1 (de) * | 2006-12-08 | 2008-06-12 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung von Herzinsuffizienz mittels Neurophysin |
| DE102006060112A1 (de) * | 2006-12-20 | 2008-06-26 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung mittels dem neuen Marker CT-proADM |
| WO2009019215A1 (en) * | 2007-08-03 | 2009-02-12 | Dkfz Deutsches Krebsforschungszentrum | Method for prenatal diagnosis using exosomes and cd24 as a marker |
| CN101377492B (zh) * | 2007-08-29 | 2014-04-23 | 北京九强生物技术股份有限公司 | 胱抑素c测定试剂盒 |
| KR100970651B1 (ko) * | 2007-11-01 | 2010-07-15 | 남명진 | 난소암 진단용 키트 |
| WO2010056337A2 (en) * | 2008-11-12 | 2010-05-20 | Caris Mpi, Inc. | Methods and systems of using exosomes for determining phenotypes |
-
2011
- 2011-01-07 JP JP2012547511A patent/JP5732474B2/ja not_active Expired - Fee Related
- 2011-01-07 CA CA2785592A patent/CA2785592A1/en not_active Abandoned
- 2011-01-07 CN CN201180005605.4A patent/CN102812362B/zh not_active Expired - Fee Related
- 2011-01-07 EP EP11700025.7A patent/EP2521918B1/en not_active Not-in-force
- 2011-01-07 AU AU2011204625A patent/AU2011204625B2/en not_active Ceased
- 2011-01-07 WO PCT/EP2011/050171 patent/WO2011083145A1/en not_active Ceased
- 2011-01-07 DK DK11700025.7T patent/DK2521918T3/en active
- 2011-01-07 US US13/516,417 patent/US20120309041A1/en not_active Abandoned
- 2011-01-07 SG SG2012047627A patent/SG181963A1/en unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114150057A (zh) * | 2021-12-21 | 2022-03-08 | 贾龙飞 | 一种诊断阿尔茨海默病的外泌体蛋白及其用途 |
| CN114150057B (zh) * | 2021-12-21 | 2024-04-26 | 贾龙飞 | 一种诊断阿尔茨海默病的外泌体蛋白及其用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102812362A (zh) | 2012-12-05 |
| EP2521918A1 (en) | 2012-11-14 |
| EP2521918B1 (en) | 2015-03-25 |
| AU2011204625B2 (en) | 2014-05-22 |
| DK2521918T3 (en) | 2015-06-29 |
| CN102812362B (zh) | 2015-02-11 |
| WO2011083145A1 (en) | 2011-07-14 |
| SG181963A1 (en) | 2012-08-30 |
| US20120309041A1 (en) | 2012-12-06 |
| JP2013516619A (ja) | 2013-05-13 |
| JP5732474B2 (ja) | 2015-06-10 |
| AU2011204625A1 (en) | 2012-07-12 |
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