CA2773694A1 - Microorganisms and methods for the co-production of isopropanol with primary alcohols, diols and acids - Google Patents
Microorganisms and methods for the co-production of isopropanol with primary alcohols, diols and acids Download PDFInfo
- Publication number
- CA2773694A1 CA2773694A1 CA2773694A CA2773694A CA2773694A1 CA 2773694 A1 CA2773694 A1 CA 2773694A1 CA 2773694 A CA2773694 A CA 2773694A CA 2773694 A CA2773694 A CA 2773694A CA 2773694 A1 CA2773694 A1 CA 2773694A1
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- Prior art keywords
- coa
- pathway
- isopropanol
- exogenous nucleic
- nucleic acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 title claims abstract description 1139
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- 238000004519 manufacturing process Methods 0.000 title claims description 47
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- 239000002253 acid Substances 0.000 title description 6
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- 150000007513 acids Chemical class 0.000 title description 2
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- WERYXYBDKMZEQL-UHFFFAOYSA-N butane-1,4-diol Chemical compound OCCCCO WERYXYBDKMZEQL-UHFFFAOYSA-N 0.000 claims abstract description 137
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
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| US24095909P | 2009-09-09 | 2009-09-09 | |
| US61/240,959 | 2009-09-09 | ||
| US25465009P | 2009-10-23 | 2009-10-23 | |
| US61/254,650 | 2009-10-23 | ||
| PCT/US2010/048318 WO2011031897A1 (en) | 2009-09-09 | 2010-09-09 | Microorganisms and methods for the co-production of isopropanol with primary alcohols, diols and acids |
Publications (1)
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|---|---|
| CA2773694A1 true CA2773694A1 (en) | 2011-03-17 |
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| CA2773694A Abandoned CA2773694A1 (en) | 2009-09-09 | 2010-09-09 | Microorganisms and methods for the co-production of isopropanol with primary alcohols, diols and acids |
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| Country | Link |
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| US (2) | US8715971B2 (enExample) |
| EP (2) | EP2933338A3 (enExample) |
| JP (1) | JP2013504326A (enExample) |
| KR (1) | KR20120068021A (enExample) |
| CN (2) | CN107586753A (enExample) |
| BR (1) | BR112012005296A2 (enExample) |
| CA (1) | CA2773694A1 (enExample) |
| MX (1) | MX2012003025A (enExample) |
| PH (1) | PH12012500463A1 (enExample) |
| SG (1) | SG179048A1 (enExample) |
| WO (1) | WO2011031897A1 (enExample) |
| ZA (2) | ZA201201468B (enExample) |
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| US8129154B2 (en) | 2008-06-17 | 2012-03-06 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate |
| EP3514242A3 (en) | 2008-09-10 | 2019-08-28 | Genomatica, Inc. | Microrganisms for the production of 1,4-butanediol |
| WO2010071697A1 (en) | 2008-12-16 | 2010-06-24 | Genomatica, Inc. | Microorganisms and methods for conversion of syngas and other carbon sources to useful products |
| EP3696158A1 (en) | 2009-06-04 | 2020-08-19 | Genomatica, Inc. | Process of separating components of a fermentation broth |
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-
2010
- 2010-09-09 MX MX2012003025A patent/MX2012003025A/es active IP Right Grant
- 2010-09-09 WO PCT/US2010/048318 patent/WO2011031897A1/en not_active Ceased
- 2010-09-09 CN CN201710897714.0A patent/CN107586753A/zh active Pending
- 2010-09-09 CA CA2773694A patent/CA2773694A1/en not_active Abandoned
- 2010-09-09 SG SG2012016408A patent/SG179048A1/en unknown
- 2010-09-09 EP EP15155588.5A patent/EP2933338A3/en not_active Withdrawn
- 2010-09-09 PH PH1/2012/500463A patent/PH12012500463A1/en unknown
- 2010-09-09 JP JP2012528907A patent/JP2013504326A/ja active Pending
- 2010-09-09 CN CN2010800504376A patent/CN102625845A/zh active Pending
- 2010-09-09 EP EP10816105A patent/EP2475775A4/en not_active Withdrawn
- 2010-09-09 BR BR112012005296A patent/BR112012005296A2/pt not_active IP Right Cessation
- 2010-09-09 US US12/878,980 patent/US8715971B2/en active Active
- 2010-09-09 KR KR1020127008948A patent/KR20120068021A/ko not_active Withdrawn
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2475775A1 (en) | 2012-07-18 |
| WO2011031897A1 (en) | 2011-03-17 |
| EP2933338A3 (en) | 2016-01-06 |
| CN107586753A (zh) | 2018-01-16 |
| ZA201301486B (en) | 2014-10-29 |
| ZA201201468B (en) | 2013-05-29 |
| EP2475775A4 (en) | 2013-03-20 |
| KR20120068021A (ko) | 2012-06-26 |
| US20110201068A1 (en) | 2011-08-18 |
| CN102625845A (zh) | 2012-08-01 |
| US20140377820A1 (en) | 2014-12-25 |
| US8715971B2 (en) | 2014-05-06 |
| JP2013504326A (ja) | 2013-02-07 |
| SG179048A1 (en) | 2012-04-27 |
| EP2933338A2 (en) | 2015-10-21 |
| PH12012500463A1 (en) | 2012-10-22 |
| BR112012005296A2 (pt) | 2019-01-15 |
| MX2012003025A (es) | 2012-06-27 |
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