CA2765406C - Stem accelerated isothermal nucleic acid amplification technology - Google Patents

Stem accelerated isothermal nucleic acid amplification technology Download PDF

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Publication number
CA2765406C
CA2765406C CA2765406A CA2765406A CA2765406C CA 2765406 C CA2765406 C CA 2765406C CA 2765406 A CA2765406 A CA 2765406A CA 2765406 A CA2765406 A CA 2765406A CA 2765406 C CA2765406 C CA 2765406C
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primer
primers
stem
region
segment
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CA2765406A
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English (en)
French (fr)
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CA2765406A1 (en
Inventor
Laurence Carlo Tisi
Olga Gandelmann
Guy Kiddle
Cathal Joseph Mcelgunn
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Lumora Ltd
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Lumora Ltd
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2765406A 2009-06-15 2010-06-15 Stem accelerated isothermal nucleic acid amplification technology Active CA2765406C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0910302.9A GB0910302D0 (en) 2009-06-15 2009-06-15 Nucleic acid amplification
GB0910302.9 2009-06-15
PCT/GB2010/001169 WO2010146349A1 (en) 2009-06-15 2010-06-15 Stem accelerated isothermal nucleic acid amplification technology

Publications (2)

Publication Number Publication Date
CA2765406A1 CA2765406A1 (en) 2010-12-23
CA2765406C true CA2765406C (en) 2019-02-26

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ID=40940851

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2765406A Active CA2765406C (en) 2009-06-15 2010-06-15 Stem accelerated isothermal nucleic acid amplification technology

Country Status (10)

Country Link
US (1) US9410190B2 (cg-RX-API-DMAC7.html)
EP (1) EP2443253B1 (cg-RX-API-DMAC7.html)
JP (2) JP5907864B2 (cg-RX-API-DMAC7.html)
CN (1) CN102652176B (cg-RX-API-DMAC7.html)
AU (1) AU2010261541B2 (cg-RX-API-DMAC7.html)
CA (1) CA2765406C (cg-RX-API-DMAC7.html)
ES (1) ES2589079T3 (cg-RX-API-DMAC7.html)
GB (1) GB0910302D0 (cg-RX-API-DMAC7.html)
WO (1) WO2010146349A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201109493B (cg-RX-API-DMAC7.html)

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EP3144396B1 (en) 2010-10-27 2020-01-01 President and Fellows of Harvard College Methods of use of toehold hairpin primer
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CA2843136C (en) 2011-07-25 2020-12-29 Oxford Nanopore Technologies Limited Hairpin loop method for double strand polynucleotide sequencing using transmembrane pores
WO2014013259A1 (en) 2012-07-19 2014-01-23 Oxford Nanopore Technologies Limited Ssb method
GB201314695D0 (en) 2013-08-16 2013-10-02 Oxford Nanopore Tech Ltd Method
CN105209634B (zh) 2013-03-08 2020-05-12 牛津纳米孔技术公司 酶停滞方法
AU2014233150A1 (en) 2013-03-15 2015-09-17 Theranos Ip Company, Llc Nucleic acid amplification
CA2906824C (en) 2013-03-15 2023-10-03 Theranos, Inc. Nucleic acid amplification
WO2014151177A1 (en) 2013-03-15 2014-09-25 3M Innovative Properties Company Sample concentrator and method of use
US10450595B2 (en) 2013-03-15 2019-10-22 Theranos Ip Company, Llc Nucleic acid amplification
CN105452480B (zh) * 2013-08-09 2020-01-31 基因生物系统股份有限公司 经由剪刀状结构的dna扩增(dasl)
SG11201601611WA (en) 2013-09-06 2016-04-28 Theranos Inc Systems and methods for detecting infectious diseases
CN103497947B (zh) * 2013-09-13 2015-08-12 浙江国际旅行卫生保健中心 一种体外新型快速环介导等温扩增方法、体外检测甲型h1n1流感病毒的试剂及方法
EP3071713B1 (en) * 2013-11-22 2021-05-12 Labrador Diagnostics LLC Nucleic acid amplification
US11286519B2 (en) 2013-12-11 2022-03-29 Accuragen Holdings Limited Methods and compositions for enrichment of amplification products
EP3495506B1 (en) 2013-12-11 2023-07-12 AccuraGen Holdings Limited Methods for detecting rare sequence variants
US11859246B2 (en) 2013-12-11 2024-01-02 Accuragen Holdings Limited Methods and compositions for enrichment of amplification products
GB201403096D0 (en) 2014-02-21 2014-04-09 Oxford Nanopore Tech Ltd Sample preparation method
US10716587B2 (en) 2014-06-13 2020-07-21 Surgis Medical Llc Surgical device with light
EP3169793B1 (en) * 2014-07-16 2022-07-06 Tangen Biosciences Inc. Isothermal methods for amplifying nucleic acid samples
WO2016073353A1 (en) 2014-11-03 2016-05-12 Tangen Biosciences, Inc. Apparatus and method for cell, spore, or virus capture and disruption
US11639522B2 (en) 2015-01-30 2023-05-02 President And Fellows Of Harvard College Microscope-free imaging
US10612073B2 (en) 2015-02-26 2020-04-07 Hitachi High-Technologies Corporation Method for constructing nucleic acid molecule
US10260090B2 (en) 2015-07-16 2019-04-16 Arizona Board Of Regents On Behalf Of Arizona State University Accelerated isothermal amplification of DNA
KR20180055905A (ko) * 2015-10-09 2018-05-25 아큐라젠 홀딩스 리미티드 증폭 산물의 농축을 위한 방법 및 조성물
WO2017096322A1 (en) 2015-12-03 2017-06-08 Accuragen Holdings Limited Methods and compositions for forming ligation products
US11286517B2 (en) 2016-02-17 2022-03-29 President And Fellows Of Harvard College Molecular programming tools
WO2017201102A1 (en) 2016-05-16 2017-11-23 Accuragen Holdings Limited Method of improved sequencing by strand identification
GB201609220D0 (en) 2016-05-25 2016-07-06 Oxford Nanopore Tech Ltd Method
CN107488656B (zh) * 2016-06-13 2020-07-17 陆欣华 一种核酸等温自扩增方法
CN109844133A (zh) 2016-08-15 2019-06-04 安可济控股有限公司 检测罕见序列变体的组合物和方法
EP3568492B1 (en) * 2017-01-10 2025-01-01 President and Fellows of Harvard College Multiplexed signal amplification
EP3724322A1 (en) 2017-12-14 2020-10-21 Medicinal Genomics Corporation Methods and kits for classifying cannabinoid production in cannabis plants
CN111630179B (zh) 2018-01-26 2024-07-19 哈佛学院院长及董事 邻近检测方法和组合物
GB201807793D0 (en) 2018-05-14 2018-06-27 Oxford Nanopore Tech Ltd Method
CN112601823A (zh) 2018-06-12 2021-04-02 安可济控股有限公司 用于形成连接产物的方法和组合物
CN114045330B (zh) * 2021-12-23 2024-02-09 川北医学院附属医院 一种基于滑动复制的核酸等温扩增方法
CN118621045A (zh) * 2024-08-14 2024-09-10 天健生物制药(天津)有限公司 基于lamp的鸟分枝杆菌检测的组合物和试剂盒

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ATE437225T1 (de) * 2000-09-19 2009-08-15 Eiken Chemical Verfahren zur polynukleotidsynthese
JPWO2002090538A1 (ja) * 2001-05-08 2004-08-26 栄研化学株式会社 核酸を合成する方法
GB0218215D0 (en) 2002-08-06 2002-09-11 Tepnel Medical Ltd Amplification of nucleic acids
WO2007025281A2 (en) 2005-08-24 2007-03-01 Applera Corporation A method to quantify sirnas, mirnas and polymorphic mirnas
JP4580875B2 (ja) * 2006-01-20 2010-11-17 株式会社東芝 核酸検出法のためのプライマーの設計方法
JP2008029333A (ja) 2006-07-03 2008-02-14 Fujifilm Corp 新規遺伝子増幅法に用いられるプライマー
EP2069540B1 (en) 2006-10-09 2014-03-19 Oxitec Limited Methods for amplifying and detecting nucleic acid sequences
JP4490988B2 (ja) * 2007-04-26 2010-06-30 株式会社東芝 血清アミロイドa1(saa1)の遺伝子型を検出するための核酸プライマーセット、キット、及び該プライマーセットを用いた検出方法
US8748100B2 (en) 2007-08-30 2014-06-10 The Chinese University Of Hong Kong Methods and kits for selectively amplifying, detecting or quantifying target DNA with specific end sequences

Also Published As

Publication number Publication date
WO2010146349A1 (en) 2010-12-23
JP5907864B2 (ja) 2016-04-26
CN102652176A (zh) 2012-08-29
JP6106732B2 (ja) 2017-04-05
JP2016041070A (ja) 2016-03-31
AU2010261541B2 (en) 2016-03-10
US9410190B2 (en) 2016-08-09
EP2443253A1 (en) 2012-04-25
CN102652176B (zh) 2016-09-28
CA2765406A1 (en) 2010-12-23
AU2010261541A1 (en) 2012-02-02
EP2443253B1 (en) 2016-06-08
JP2012529904A (ja) 2012-11-29
US20120157326A1 (en) 2012-06-21
GB0910302D0 (en) 2009-07-29
ZA201109493B (en) 2015-07-29
ES2589079T3 (es) 2016-11-10

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