CA2740788C - Methods and compositions for diagnosis and prognosis of renal injury and renal failure - Google Patents
Methods and compositions for diagnosis and prognosis of renal injury and renal failure Download PDFInfo
- Publication number
- CA2740788C CA2740788C CA2740788A CA2740788A CA2740788C CA 2740788 C CA2740788 C CA 2740788C CA 2740788 A CA2740788 A CA 2740788A CA 2740788 A CA2740788 A CA 2740788A CA 2740788 C CA2740788 C CA 2740788C
- Authority
- CA
- Canada
- Prior art keywords
- subject
- hours
- likelihood
- assigning
- serum creatinine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Physiology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (59)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10729008P | 2008-10-21 | 2008-10-21 | |
| US10729708P | 2008-10-21 | 2008-10-21 | |
| US10730408P | 2008-10-21 | 2008-10-21 | |
| US10728108P | 2008-10-21 | 2008-10-21 | |
| US10730108P | 2008-10-21 | 2008-10-21 | |
| US61/107,281 | 2008-10-21 | ||
| US61/107,297 | 2008-10-21 | ||
| US61/107,304 | 2008-10-21 | ||
| US61/107,301 | 2008-10-21 | ||
| US61/107,290 | 2008-10-21 | ||
| US11310208P | 2008-11-10 | 2008-11-10 | |
| US11309608P | 2008-11-10 | 2008-11-10 | |
| US11305008P | 2008-11-10 | 2008-11-10 | |
| US11304508P | 2008-11-10 | 2008-11-10 | |
| US11302108P | 2008-11-10 | 2008-11-10 | |
| US11308308P | 2008-11-10 | 2008-11-10 | |
| US11305608P | 2008-11-10 | 2008-11-10 | |
| US61/113,056 | 2008-11-10 | ||
| US61/113,045 | 2008-11-10 | ||
| US61/113,102 | 2008-11-10 | ||
| US61/113,083 | 2008-11-10 | ||
| US61/113,096 | 2008-11-10 | ||
| US61/113,050 | 2008-11-10 | ||
| US61/113,021 | 2008-11-10 | ||
| US11501708P | 2008-11-14 | 2008-11-14 | |
| US11502208P | 2008-11-14 | 2008-11-14 | |
| US11501908P | 2008-11-14 | 2008-11-14 | |
| US61/115,017 | 2008-11-14 | ||
| US61/115,019 | 2008-11-14 | ||
| US61/115,022 | 2008-11-14 | ||
| US11504508P | 2008-11-15 | 2008-11-15 | |
| US11504408P | 2008-11-15 | 2008-11-15 | |
| US11504808P | 2008-11-15 | 2008-11-15 | |
| US11505708P | 2008-11-15 | 2008-11-15 | |
| US11504708P | 2008-11-15 | 2008-11-15 | |
| US11505108P | 2008-11-15 | 2008-11-15 | |
| US61/115,047 | 2008-11-15 | ||
| US61/115,045 | 2008-11-15 | ||
| US61/115,057 | 2008-11-15 | ||
| US61/115,051 | 2008-11-15 | ||
| US61/115,044 | 2008-11-15 | ||
| US61/115,048 | 2008-11-15 | ||
| US11715408P | 2008-11-22 | 2008-11-22 | |
| US11717208P | 2008-11-22 | 2008-11-22 | |
| US11715708P | 2008-11-22 | 2008-11-22 | |
| US11716708P | 2008-11-22 | 2008-11-22 | |
| US11714608P | 2008-11-22 | 2008-11-22 | |
| US11714108P | 2008-11-22 | 2008-11-22 | |
| US11714008P | 2008-11-22 | 2008-11-22 | |
| US11715208P | 2008-11-22 | 2008-11-22 | |
| US61/117,140 | 2008-11-22 | ||
| US61/117,154 | 2008-11-22 | ||
| US61/117,167 | 2008-11-22 | ||
| US61/117,172 | 2008-11-22 | ||
| US61/117,141 | 2008-11-22 | ||
| US61/117,152 | 2008-11-22 | ||
| US61/117,146 | 2008-11-22 | ||
| US61/117,157 | 2008-11-22 | ||
| PCT/US2009/061561 WO2010048346A1 (en) | 2008-10-21 | 2009-10-21 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2740788A1 CA2740788A1 (en) | 2010-04-29 |
| CA2740788C true CA2740788C (en) | 2023-03-14 |
Family
ID=42119666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2740788A Active CA2740788C (en) | 2008-10-21 | 2009-10-21 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US8778615B2 (https=) |
| EP (4) | EP3974836A1 (https=) |
| JP (4) | JP2012506537A (https=) |
| KR (1) | KR101760314B1 (https=) |
| CN (6) | CN106370857A (https=) |
| AU (1) | AU2009308497B2 (https=) |
| BR (1) | BRPI0919640A2 (https=) |
| CA (1) | CA2740788C (https=) |
| ES (1) | ES2836218T3 (https=) |
| MX (1) | MX2011004174A (https=) |
| NZ (3) | NZ607703A (https=) |
| WO (1) | WO2010048346A1 (https=) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX340916B (es) | 2008-01-18 | 2016-07-29 | President And Fellows Of Harvard College * | Metodos para detectar señales de identificacion de enfermedad o condiciones en fluidos corporales. |
| GB0807214D0 (en) | 2008-04-21 | 2008-05-28 | Belfast Health And Social Care | Biomarkers |
| NZ610356A (en) * | 2008-08-28 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CA2735590A1 (en) * | 2008-08-29 | 2010-03-04 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| NZ607703A (en) | 2008-10-21 | 2014-09-26 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2010048347A2 (en) * | 2008-10-21 | 2010-04-29 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN102264230B (zh) | 2008-11-10 | 2014-12-10 | 阿斯图特医药公司 | 用于诊断和预后肾损伤和肾衰竭的方法和组合物 |
| MX2011005379A (es) * | 2008-11-22 | 2011-06-09 | Astute Medical Inc | Metodos y composiciones para diagnosis y prognosis de lesion renal y falla renal. |
| US9229010B2 (en) | 2009-02-06 | 2016-01-05 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CA2770393A1 (en) | 2009-08-07 | 2011-02-10 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| NZ630277A (en) * | 2009-09-21 | 2015-02-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CA2779905A1 (en) * | 2009-11-07 | 2011-05-12 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP2496942B1 (en) | 2009-11-07 | 2017-03-22 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| JP5763098B2 (ja) * | 2009-12-20 | 2015-08-12 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| US20120156701A1 (en) * | 2009-12-20 | 2012-06-21 | Joseph Anderberg | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| PT2666872T (pt) | 2010-02-05 | 2016-07-08 | Astute Medical Inc | Processos e composições para o diagnóstico e o prognóstico de lesões renais e de insuficiência renal |
| EP3070474A3 (en) * | 2010-02-26 | 2016-12-07 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| IN2012MN02812A (https=) | 2010-06-23 | 2015-05-22 | Astute Medical Inc | |
| NZ605698A (en) | 2010-06-23 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US20130157297A1 (en) * | 2010-07-14 | 2013-06-20 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| KR20130126576A (ko) * | 2010-07-19 | 2013-11-20 | 에프. 호프만-라 로슈 아게 | 항암요법에 반응할 가능성이 증가된 환자를 확인하는 방법 |
| CA2806296A1 (en) | 2010-07-23 | 2012-01-26 | President And Fellows Of Harvard College | Methods of detecting kidney-associated diseases or conditions |
| EP2596132A4 (en) | 2010-07-23 | 2013-12-18 | Harvard College | METHOD FOR DETECTING SIGNS FOR ILLNESS OR SUFFERING IN BODY FLUIDS |
| TW201209171A (en) | 2010-07-23 | 2012-03-01 | Harvard College | Methods of detecting diseases or conditions using phagocytic cells |
| US20130203624A1 (en) | 2010-07-23 | 2013-08-08 | President And Fellows Of Harvard College | Methods of Detecting Prenatal or Pregnancy-Related Diseases or Conditions |
| AU2011280997A1 (en) | 2010-07-23 | 2013-02-28 | President And Fellows Of Harvard College | Methods of detecting autoimmune or immune-related diseases or conditions |
| CA2824434A1 (en) * | 2011-01-08 | 2012-07-12 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2012094657A1 (en) * | 2011-01-08 | 2012-07-12 | Astute Medical, Inc. | Method and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP2668497B1 (en) * | 2011-01-26 | 2020-03-25 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Urine biomarkers for prediction of recovery after acute kidney injury : proteomics |
| EP2518512A1 (en) | 2011-04-29 | 2012-10-31 | Medizinische Universität Wien | Method for indicating a renal disease in a patient by determining at least one protein in isolated HDL |
| WO2012155123A2 (en) * | 2011-05-12 | 2012-11-15 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN103874923B (zh) * | 2011-08-26 | 2016-09-14 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断及预后的方法和组合物 |
| ES2734494T3 (es) | 2011-12-08 | 2019-12-10 | Astute Medical Inc | Métodos y usos para el diagnóstico de una lesión renal y de una insuficiencia renal |
| WO2013113018A1 (en) * | 2012-01-28 | 2013-08-01 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP2820419B1 (en) * | 2012-02-27 | 2020-12-09 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| IN2014MN01759A (https=) * | 2012-02-27 | 2015-07-03 | Astute Medical Inc | |
| GB201210571D0 (en) | 2012-06-14 | 2012-08-01 | Belfast Health And Social Care Trust | Predictive biomarker |
| GB201210587D0 (en) * | 2012-06-14 | 2012-08-01 | Belfast Health And Social Care Trust | Predictive biomarker |
| GB201214440D0 (en) * | 2012-08-13 | 2012-09-26 | Randox Lab Ltd | Kidney disease biomarker |
| EP2719771A1 (en) * | 2012-10-11 | 2014-04-16 | Ciber de Enfermedades Respiratorias (CIBERES) | Marker for assessing the risk of developing acute kidney injury |
| TR201807542T4 (tr) | 2013-01-17 | 2018-06-21 | Astute Medical Inc | Böbrek hasarı ve böbrek yetmezliği teşhisi ve prognozuna yönelik metotlar ve bileşimler. |
| WO2014164362A1 (en) | 2013-03-09 | 2014-10-09 | Harry Stylli | Methods of detecting prostate cancer |
| NZ771629A (en) | 2013-03-09 | 2022-12-23 | Harry Stylli | Methods of detecting cancer |
| EP3617234A1 (en) | 2013-08-07 | 2020-03-04 | Astute Medical, Inc. | Assays for timp2 having improved performance in biological samples |
| EP3441768A3 (en) * | 2013-08-26 | 2019-03-20 | Roche Diagnostics GmbH | Marker for statin treatment stratification in heart failure |
| US10300108B2 (en) | 2013-12-03 | 2019-05-28 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| SG11201607487UA (en) * | 2014-03-21 | 2016-10-28 | Sanofi Aventis Deutschland | New markers for the assessment of the risk for development of a cardiovascular disorder |
| US10626464B2 (en) | 2014-09-11 | 2020-04-21 | Cell Mdx, Llc | Methods of detecting prostate cancer |
| US10473671B2 (en) | 2014-12-18 | 2019-11-12 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2016133667A1 (en) | 2015-02-20 | 2016-08-25 | 3M Innovative Properties Company | Silicone carbonate polymers as release layers for pressure sensitive adhesive containing articles |
| US11243202B2 (en) | 2015-04-09 | 2022-02-08 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2016176483A1 (en) * | 2015-04-28 | 2016-11-03 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN107709993A (zh) * | 2015-06-11 | 2018-02-16 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断和预后的方法和组合物 |
| EP3465201A4 (en) | 2016-06-06 | 2020-08-26 | Astute Medical, Inc. | MANAGEMENT OF ACUTE KIDNEY DAMAGE USING INSULINOMIMETIC GROWTH FACTOR BINDING PROTEIN 7 AND TISSUE METALLOPROTEINASE 2 INHIBITOR |
| CN106370856B (zh) * | 2016-08-16 | 2019-04-02 | 北京师范大学 | 肺纤维化的尿液蛋白标志物及其在诊断和预后中的用途 |
| CN110352073A (zh) | 2016-10-28 | 2019-10-18 | 机敏医药股份有限公司 | 针对timp-2的抗体用于改善肾功能的用途 |
| JP2018096710A (ja) * | 2016-12-08 | 2018-06-21 | 国立大学法人金沢大学 | 血中タンパク質を測定することにより、ネフローゼ症候群の疾患活動性を判定する方法 |
| US20200174014A1 (en) | 2016-12-19 | 2020-06-04 | Osaka University | METHOD FOR IN VITRO EARLY DIAGNOSIS OF ANTIBODY MEDIATED REJECTION AFTER ORGAN TRANSPLANTATION USING IgM-TYPE MEMORY B CELL DIFFERENTIATION CULTURE SYSTEM |
| US11346846B2 (en) | 2017-02-06 | 2022-05-31 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US11718682B2 (en) | 2017-04-05 | 2023-08-08 | Astute Medical, Inc. | Assays for TIMP2 having improved performance in biological samples |
| CN109975553B (zh) * | 2017-12-28 | 2020-10-09 | 北京师范大学 | 慢性阻塞性肺病的尿液蛋白标志物及其在早期诊断中的用途 |
| KR20210019459A (ko) | 2018-05-24 | 2021-02-22 | 레니버스 테라퓨틱스, 인크. | 신장 손상 및 신부전 위험이 있는 환자를 치료하는 방법 |
| KR102319190B1 (ko) * | 2018-12-19 | 2021-10-29 | 서울대학교병원 | 신장 질환 진단용 바이오 마커 |
| KR102077987B1 (ko) * | 2018-12-19 | 2020-02-17 | 주식회사 헬릭스미스 | 신장 질환 진단용 바이오 마커 |
| GB201912856D0 (en) * | 2019-09-06 | 2019-10-23 | Nordic Bioscience As | Assay for assessing heart failure |
| RU2726314C1 (ru) * | 2019-11-15 | 2020-07-14 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Тихоокеанский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Способ раннего прогнозирования риска острого повреждения почек у пациентов с ишемической болезнью сердца после реваскуляризации миокарда методом аортокоронарного шунтирования |
| JP7599310B2 (ja) | 2020-11-02 | 2024-12-13 | テルモ株式会社 | 急性腎障害発症予測装置、急性腎障害発症予測装置の制御方法、急性腎障害発症予測プログラム |
| CN115469026B (zh) * | 2022-07-14 | 2023-10-20 | 中日友好医院(中日友好临床医学研究所) | 用于检测环孢素a肾毒性相关标志物的检测试剂、试剂盒及其用途 |
| CN117711618B (zh) * | 2023-12-15 | 2024-08-06 | 南方医科大学南方医院 | 一种基于蛋白质的肾脏病发生风险预测系统及存储介质 |
| CN117890600A (zh) * | 2024-01-11 | 2024-04-16 | 华中科技大学同济医学院附属同济医院 | CXCL16检测剂在制备IgA肾病患者预后试剂中的应用 |
| CN120260975A (zh) * | 2025-06-05 | 2025-07-04 | 山东中医药大学附属医院 | 一种肾病病理分析系统 |
Family Cites Families (152)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1429031A1 (ru) | 1986-06-20 | 1988-10-07 | Калининский Государственный Медицинский Институт | Способ дифференциальной диагностики гломерулонефрита и пиелонефрита |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5028535A (en) | 1989-01-10 | 1991-07-02 | Biosite Diagnostics, Inc. | Threshold ligand-receptor assay |
| US5939272A (en) | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
| US5922615A (en) | 1990-03-12 | 1999-07-13 | Biosite Diagnostics Incorporated | Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network |
| CA2072758A1 (en) | 1990-09-14 | 1992-03-15 | Kenneth Francis Buechler | Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays |
| US5955377A (en) | 1991-02-11 | 1999-09-21 | Biostar, Inc. | Methods and kits for the amplification of thin film based assays |
| CA2107894C (en) | 1991-04-10 | 2003-10-14 | Kenneth F. Buechler | Crosstalk inhibitors and their uses |
| EP0579767B1 (en) | 1991-04-11 | 2000-08-23 | Biosite Diagnostics Inc. | Novel conjugates and assays for simultaneous detection of multiple ligands |
| US6143576A (en) | 1992-05-21 | 2000-11-07 | Biosite Diagnostics, Inc. | Non-porous diagnostic devices for the controlled movement of reagents |
| US6019944A (en) | 1992-05-21 | 2000-02-01 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
| US5494829A (en) | 1992-07-31 | 1996-02-27 | Biostar, Inc. | Devices and methods for detection of an analyte based upon light interference |
| US5824799A (en) | 1993-09-24 | 1998-10-20 | Biosite Diagnostics Incorporated | Hybrid phthalocyanine derivatives and their uses |
| JP3569577B2 (ja) * | 1995-09-04 | 2004-09-22 | 株式会社いかがく | 腎・尿路系疾患の鑑別診断用キット |
| JP3599895B2 (ja) * | 1996-04-05 | 2004-12-08 | 株式会社いかがく | 糖尿病性腎症および糸球体腎炎の早期診断用キット |
| US6498142B1 (en) | 1996-05-06 | 2002-12-24 | Curis, Inc. | Morphogen treatment for chronic renal failure |
| ES2258793T5 (es) | 1996-05-24 | 2010-01-25 | Biogen Idec Ma Inc. | Moduladores de la regeneracion tisular. |
| US5753455A (en) | 1996-09-03 | 1998-05-19 | Bayer Corporation | Method for the detection of lysozyme using a protein error indicator dye in conjunction with an alkane sulfonic acid |
| US6113855A (en) | 1996-11-15 | 2000-09-05 | Biosite Diagnostics, Inc. | Devices comprising multiple capillarity inducing surfaces |
| US5947124A (en) | 1997-03-11 | 1999-09-07 | Biosite Diagnostics Incorporated | Diagnostic for determining the time of a heart attack |
| US6057098A (en) | 1997-04-04 | 2000-05-02 | Biosite Diagnostics, Inc. | Polyvalent display libraries |
| AU7549498A (en) | 1997-06-03 | 1998-12-21 | Protegene Inc. | Human proteins having transmembrane domains and dnas encoding these prot eins |
| US20060223077A1 (en) | 1997-06-06 | 2006-10-05 | Human Genome Sciences, Inc. | 207 human secreted proteins |
| US6218122B1 (en) | 1998-06-19 | 2001-04-17 | Rosetta Inpharmatics, Inc. | Methods of monitoring disease states and therapies using gene expression profiles |
| US6958147B1 (en) | 1998-10-26 | 2005-10-25 | Licentia Ltd | Use of VEGF-C to prevent restenosis |
| CA2356174A1 (en) | 1998-12-21 | 2000-06-29 | Monash University | Kidney disease detection and treatment |
| US6602674B1 (en) * | 1999-10-18 | 2003-08-05 | The Board Of Trustees Of The University Of Arkansas | Uses of antileukoprotease in carcinoma |
| EP1150123B1 (en) * | 2000-04-28 | 2006-07-12 | Bayer Aktiengesellschaft | Diagnosis of liver fibrosis with serum marker algorithms |
| JP2003533699A (ja) | 2000-05-17 | 2003-11-11 | ネーデルランドセ・オルガニザテイエ・フール・テゲパスト−ナトウールベテンシヤツペリーク・オンデルツエク・テイエヌオー | 腎臓障害の診断における蛋白分解酵素 |
| CA2408743A1 (en) | 2000-05-25 | 2001-11-29 | Curagen Corporation | Method of detecting inflammatory lung disorders |
| RU2180965C1 (ru) | 2000-07-03 | 2002-03-27 | Габбасова Наталья Вадимовна | Способ дифференциальной диагностики заболеваний почек |
| AU2002216273A1 (en) * | 2000-12-29 | 2002-07-16 | Oxford Glycosciences (Uk) Limited | Proteins, genes and their use for diagnosis and treatment of kidney response |
| US20060088823A1 (en) | 2001-03-29 | 2006-04-27 | Brian Haab | Microarray gene expression profiling in clear cell renal cell carcinoma : prognosis and drug target identification |
| US20070015146A1 (en) | 2001-05-22 | 2007-01-18 | Gene Logic, Inc. | Molecular nephrotoxicology modeling |
| US7235358B2 (en) | 2001-06-08 | 2007-06-26 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| US20030003588A1 (en) | 2001-06-28 | 2003-01-02 | Comper Wayne D. | Method for kidney disease detection by protein profiling |
| US20040241744A1 (en) * | 2001-07-12 | 2004-12-02 | Hiroaki Kohno | Method of quantifying denatured lipoprotein, reagents for quantifying denatured lipoprotein, method of detecting circulatory disease and reagents for detecting circulatory disease |
| JP2006508014A (ja) | 2001-07-24 | 2006-03-09 | イエール・ユニバーシテイ | キチナーゼおよびキチナーゼ様分子、ならびに炎症性疾患に関する方法、組成物およびキット |
| US6784154B2 (en) | 2001-11-01 | 2004-08-31 | University Of Utah Research Foundation | Method of use of erythropoietin to treat ischemic acute renal failure |
| US8404229B2 (en) | 2001-12-07 | 2013-03-26 | Cytori Therapeutics, Inc. | Methods of using adipose derived stem cells to treat acute tubular necrosis |
| GB0130557D0 (en) | 2001-12-20 | 2002-02-06 | Serono Internat S A | Proteins |
| EP1481249A1 (en) | 2002-03-07 | 2004-12-01 | Cambridge University Technical Services Limited | Scd fingerprints |
| WO2003081201A2 (en) | 2002-03-21 | 2003-10-02 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Peripheral blood cell markers useful for diagnosing multiple sclerosis and methods and kits utilizing same |
| US7138229B2 (en) | 2002-12-06 | 2006-11-21 | Renovar, Inc. | Systems and methods for characterizing kidney diseases |
| US7138230B2 (en) * | 2002-12-06 | 2006-11-21 | Renovar, Inc. | Systems and methods for characterizing kidney diseases |
| WO2003099107A2 (en) * | 2002-05-22 | 2003-12-04 | The Cleveland Clinic Foundation | Methods and kits for the detection of renal cell carcinoma in a biological fluid of a patient |
| WO2004005934A2 (en) | 2002-07-04 | 2004-01-15 | Oxford Glycosciences (Uk) Ltd | Toxicity markers |
| AU2003269837B9 (en) * | 2002-09-26 | 2009-07-30 | Hvidovre Hospital | A method for detecting, screening and/or monitoring a cancer in an individual |
| US6941172B2 (en) | 2002-11-18 | 2005-09-06 | Zvi Nachum | Method and device for restoring kidney function using electromagnetic stimulation |
| WO2004053074A2 (en) | 2002-12-06 | 2004-06-24 | Science And Technology Corporation @ Unm | Outcome prediction and risk classification in childhood leukemia |
| JP2005120070A (ja) | 2003-03-10 | 2005-05-12 | Taisho Pharmaceut Co Ltd | エラスターゼ遊離抑制剤及び脳梗塞治療薬 |
| CN1791797A (zh) * | 2003-03-27 | 2006-06-21 | 儿童医院医疗中心 | 用于检测肾小管细胞损伤的早发的方法和试剂盒 |
| AU2004229501B2 (en) | 2003-04-11 | 2011-08-18 | Medimmune, Llc | Recombinant IL-9 antibodies and uses thereof |
| US7560244B2 (en) | 2003-06-04 | 2009-07-14 | Joslin Diabetes Center, Inc. | Method of evaluating a subject for risk or predisposition of reduced renal function over time |
| US20050148029A1 (en) | 2003-09-29 | 2005-07-07 | Biosite, Inc. | Methods and compositions for determining treatment regimens in systemic inflammatory response syndromes |
| US7670764B2 (en) * | 2003-10-24 | 2010-03-02 | Prometheus Laboratories Inc. | Methods of diagnosing tissue fibrosis |
| GB0329288D0 (en) | 2003-12-18 | 2004-01-21 | Inverness Medical Switzerland | Monitoring method and apparatus |
| US20070280930A1 (en) | 2004-03-17 | 2007-12-06 | Kasper Mathias Antoon Rouschop | Cd44-Targeting for Reducing/Preventing Ischemia-Reperfusion-Injury |
| AU2005236075A1 (en) | 2004-04-26 | 2005-11-03 | Children's Medical Center Corporation | Platelet biomarkers for the detection of disease |
| CN101010001A (zh) * | 2004-05-06 | 2007-08-01 | 哥伦比亚大学受托人 | Ngal用于减少和改善局部缺血和肾中毒损伤 |
| US20050272101A1 (en) * | 2004-06-07 | 2005-12-08 | Prasad Devarajan | Method for the early detection of renal injury |
| FR2872579B1 (fr) | 2004-06-30 | 2006-11-24 | Pasteur Institut | Detection de la tuberculose et de l'infection par mycobacterium tuberculosis a l'aide de hbha |
| US7588892B2 (en) | 2004-07-19 | 2009-09-15 | Entelos, Inc. | Reagent sets and gene signatures for renal tubule injury |
| WO2006008661A2 (en) | 2004-07-19 | 2006-01-26 | Neurochem (International) Limited | Diagnostic methods of multiple organ amyloidosis |
| US7141382B1 (en) | 2004-10-12 | 2006-11-28 | Parikh Chirag R | Methods for detection of IL-18 as an early marker for diagnosis of acute renal failure and predictor of mortality |
| EP1846576A4 (en) | 2005-02-01 | 2009-01-07 | Us Gov Health & Human Serv | BIOMARKERS OF TISSUE STATUS |
| DE102005005872A1 (de) | 2005-02-09 | 2006-08-10 | Deutsche Thomson-Brandt Gmbh | Getaktete Stromversorgung |
| EP2604703B1 (en) | 2005-03-14 | 2017-02-01 | The Board of Trustees of the Leland Stanford Junior University | Methods for evaluating graft survival in a solid organ transplant recipient |
| US7608413B1 (en) | 2005-03-25 | 2009-10-27 | Celera Corporation | Kidney disease targets and uses thereof |
| US20070037232A1 (en) | 2005-03-31 | 2007-02-15 | Barasch Jonathan M | Detection of NGAL in chronic renal disease |
| EP1877559B1 (en) | 2005-04-18 | 2010-10-13 | Mitomics Inc. | Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers |
| US20070087387A1 (en) | 2005-04-21 | 2007-04-19 | Prasad Devarajan | Method for the Early Detection of Renal Disease Using Proteomics |
| US20090178145A1 (en) | 2005-05-11 | 2009-07-09 | The Procter & Gamble Company | Methods and targets for identifying compounds for regulating angiogenesis |
| CA2609262A1 (en) * | 2005-06-03 | 2006-12-07 | Mochida Pharmaceutical Co., Ltd. | Anti-cd14 antibody fusion protein |
| AU2006272913B2 (en) | 2005-07-21 | 2012-01-19 | The Johns Hopkins University | Methods of detecting and treating acute kidney injury |
| US7759077B2 (en) | 2005-08-02 | 2010-07-20 | Shariat Shahrokh F | Soluble fas urinary marker for the detection of bladder transitional cell carcinoma |
| EP1757940A1 (en) | 2005-08-26 | 2007-02-28 | Cézanne S.A.S. | In vitro method for diagnosing and monitoring renal cell carcinoma (RCC) using MMP-7 as humoral biomarker for RCC |
| DK1764372T3 (da) * | 2005-09-20 | 2009-11-30 | Peter Jon Nelson | Vævsinhibitor af metalloproteinaser (TIMP) bundet til glycosylphosphatidylinositol (GPI)-ankre til behandling af cancer |
| AU2006299417A1 (en) | 2005-10-03 | 2007-04-12 | Biosite Incorporated | Methods and compositions for diagnosis and/or prognosis in Systemic Inflammatory Response Syndromes |
| US20080090304A1 (en) | 2006-10-13 | 2008-04-17 | Barasch Jonathan Matthew | Diagnosis and monitoring of chronic renal disease using ngal |
| US8329408B2 (en) | 2005-10-31 | 2012-12-11 | Bayer Healthcare Llc | Methods for prognosis and monitoring cancer therapy |
| US10716749B2 (en) | 2005-11-03 | 2020-07-21 | Palo Alto Investors | Methods and compositions for treating a renal disease condition in a subject |
| US20080133141A1 (en) | 2005-12-22 | 2008-06-05 | Frost Stephen J | Weighted Scoring Methods and Use Thereof in Screening |
| TW200726845A (en) | 2006-01-02 | 2007-07-16 | Nat Defense Medical Ct | Biomarker molecular of renal illness and detecting method for the same |
| EP1982186A2 (en) * | 2006-01-12 | 2008-10-22 | Janssen Pharmaceutica, N.V. | Processing of slpi by chymase |
| US20070203216A1 (en) * | 2006-02-14 | 2007-08-30 | Bjarke Ebert | Method of treating inflammatory diseases |
| WO2007106781A2 (en) | 2006-03-10 | 2007-09-20 | University Of Rochester | Ecg-based differentiation of lqt1 and lqt2 mutation |
| GB0605217D0 (en) | 2006-03-15 | 2006-04-26 | Novartis Ag | Method and compositions for assessing acute rejection |
| GB0606776D0 (en) | 2006-04-03 | 2006-05-10 | Novartis Pharma Ag | Predictive biomarkers for chronic allograft nephropathy |
| US7662578B2 (en) | 2006-04-21 | 2010-02-16 | Children's Hospital Medical Center | Method and kit for the early detection of impaired renal status |
| GB0607943D0 (en) | 2006-04-21 | 2006-05-31 | Novartis Ag | Biomarkers for chronic transplant dysfunction |
| US20080038269A1 (en) | 2006-05-25 | 2008-02-14 | Mount Sinai Hospital | Methods for detecting and treating kidney disease |
| WO2008084331A2 (en) * | 2006-06-21 | 2008-07-17 | Hopitaux Universitaires De Geneve | Biomarkers for renal disorders |
| US20090298073A1 (en) | 2006-06-30 | 2009-12-03 | Gerhold David L | Kidney Toxicity Biomarkers |
| EP2049713A4 (en) | 2006-07-21 | 2010-06-16 | Univ Alberta | tissue rejection |
| GB0617429D0 (en) | 2006-09-05 | 2006-10-18 | Electrophoretics Ltd | Markers of renal transplant rejection and renal damage |
| US20080206794A1 (en) * | 2006-09-15 | 2008-08-28 | Renovar Incorporated | Systems And Methods For Characterizing Contrast Induced-Nephropathy |
| WO2008060607A2 (en) | 2006-11-14 | 2008-05-22 | Biosite Incorporated | Methods and compositions for monitoring and risk prediction in cardiorenal syndrome |
| EP2095106B1 (en) | 2006-11-14 | 2013-03-20 | Alere San Diego, Inc. | Methods and compositions for diagnosis and prognosis of renal artery stenosis |
| CA2665489C (en) | 2006-12-08 | 2017-08-29 | The Children's Hospital Of Philadelphia | Prrg4-associated compositions and methods of use thereof in methods of tumor diagnosis |
| GB0701626D0 (en) | 2007-01-22 | 2007-03-07 | Cambridge Entpr Ltd | Methods and biomarkers for diagnosing and monitoring psychotic disorders |
| EP1970709B1 (en) | 2007-03-06 | 2013-07-10 | Roche Diagnostics GmbH | The use of BNP-type peptides for predicting the need for dialysis |
| WO2008104803A2 (en) | 2007-02-26 | 2008-09-04 | Oxford Genome Sciences (Uk) Limited | Proteins |
| JP5105583B2 (ja) * | 2007-03-14 | 2012-12-26 | 国立大学法人信州大学 | 心血管系疾患既往区別方法 |
| US8221995B2 (en) | 2007-03-23 | 2012-07-17 | Seok-Won Lee | Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes |
| CN103399155A (zh) * | 2007-03-26 | 2013-11-20 | 诺瓦提斯公司 | 用于监测肾功能的预测性的肾安全性生物标志物和生物标志物标签 |
| EP2134866A2 (en) | 2007-04-10 | 2009-12-23 | Integragen | Human diabetes susceptibility tnfrsf10b gene |
| US8080394B2 (en) | 2007-04-27 | 2011-12-20 | Brigham And Women's Hospital | Method for determining predisposition to pulmonary infection |
| WO2008150488A1 (en) | 2007-06-01 | 2008-12-11 | Laboratory Corporation Of America Holdings | Methods and systems for quantification of peptides and other analytes |
| JP5661457B2 (ja) | 2007-06-06 | 2015-01-28 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドＳｉｅｍｅｎｓ Ｈｅａｌｔｈｃａｒｅ Ｄｉａｇｎｏｓｔｉｃｓ Ｉｎｃ． | 腎疾患の予測診断 |
| US20090047689A1 (en) | 2007-06-20 | 2009-02-19 | John Kolman | Autoantigen biomarkers for early diagnosis of lung adenocarcinoma |
| US20100267041A1 (en) | 2007-09-14 | 2010-10-21 | Predictive Biosciences, Inc. | Serial analysis of biomarkers for disease diagnosis |
| US20110059537A1 (en) | 2007-09-20 | 2011-03-10 | Caritas St. Elizabeth's Medical Center Of Boston, Inc. | Method for estimating risk of acute kidney injury |
| EP2203743A4 (en) | 2007-09-20 | 2011-03-02 | Univ Louisville Res Found | PEPTIDE BIOMARKER FOR PREDICTING WEARNING OF THE KIDNEY FUNCTION AND A CHILDNESS |
| US8003333B2 (en) | 2007-09-28 | 2011-08-23 | Mayo Foundation For Medical Education And Research | Serum biomarkers for early detection of acute cellular rejection |
| CA2716854A1 (en) | 2008-02-29 | 2009-09-03 | National University Corporation Nagoya University | Biomarker for the estimation of acute renal disorder and prognosis of the disorder, and use of the biomarker |
| US20090298106A1 (en) | 2008-05-30 | 2009-12-03 | Therapeutic Monitoring Services, L.L.C. | Methods for Monitoring Immunosuppressant Drug Levels, Renal Function, and Hepatic Function Using Small Volume Samples |
| US8241861B1 (en) | 2008-07-08 | 2012-08-14 | Insilicos, Llc | Methods and compositions for diagnosis or prognosis of cardiovascular disease |
| US20110190156A1 (en) | 2008-07-15 | 2011-08-04 | Trustees Of Dartmouth College | Molecular signatures for diagnosing scleroderma |
| US7998744B2 (en) | 2008-07-28 | 2011-08-16 | Greenwood Genetic Center, Inc. | Methods for determining dysregulation of methylation of brain expressed genes on the X chromosome to diagnose autism spectrum disorders |
| US8673574B2 (en) | 2008-08-21 | 2014-03-18 | Pxbiosciences Llc | Diagnosis and monitoring of renal failure using peptide biomarkers |
| NZ610356A (en) | 2008-08-28 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CA2735590A1 (en) | 2008-08-29 | 2010-03-04 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US8501489B2 (en) | 2008-09-26 | 2013-08-06 | University of Pittsburgh—of the Commonwealth System of Higher Education | Urinary biomarkers to predict long-term dialysis |
| NZ607703A (en) | 2008-10-21 | 2014-09-26 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2010048347A2 (en) * | 2008-10-21 | 2010-04-29 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN102264230B (zh) | 2008-11-10 | 2014-12-10 | 阿斯图特医药公司 | 用于诊断和预后肾损伤和肾衰竭的方法和组合物 |
| US9229010B2 (en) | 2009-02-06 | 2016-01-05 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP2394166B1 (en) | 2009-02-06 | 2016-07-13 | Astute Medical, Inc. | Methods for diagnosis and prognosis of renal injury and failure |
| EP2427496A4 (en) | 2009-04-03 | 2013-05-15 | Vegenics Pty Ltd | ANTI-VEGF-D ANTIBODIES |
| WO2010128158A1 (en) | 2009-05-08 | 2010-11-11 | Novartis Ag | Diagnostic biomarkers for fibrotic disorders |
| US20110065599A1 (en) | 2009-08-07 | 2011-03-17 | Rules-Based Medicine, Inc. | Methods and Devices for Detecting Kidney Damage |
| NZ630277A (en) * | 2009-09-21 | 2015-02-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| JP5763098B2 (ja) | 2009-12-20 | 2015-08-12 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| PT2666872T (pt) | 2010-02-05 | 2016-07-08 | Astute Medical Inc | Processos e composições para o diagnóstico e o prognóstico de lesões renais e de insuficiência renal |
| EP3070474A3 (en) | 2010-02-26 | 2016-12-07 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| NZ605698A (en) | 2010-06-23 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US20130210043A1 (en) | 2010-06-23 | 2013-08-15 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US20130035290A1 (en) | 2011-05-17 | 2013-02-07 | Yale University | Chitinase-3-Like Protein 1 as a Biomarker of Recovery from Kidney Injury |
| CN103874923B (zh) | 2011-08-26 | 2016-09-14 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断及预后的方法和组合物 |
| ES2734494T3 (es) | 2011-12-08 | 2019-12-10 | Astute Medical Inc | Métodos y usos para el diagnóstico de una lesión renal y de una insuficiencia renal |
| TR201807542T4 (tr) | 2013-01-17 | 2018-06-21 | Astute Medical Inc | Böbrek hasarı ve böbrek yetmezliği teşhisi ve prognozuna yönelik metotlar ve bileşimler. |
| CN105556305A (zh) | 2013-06-05 | 2016-05-04 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断及预后的方法和组合物 |
| EP3617234A1 (en) | 2013-08-07 | 2020-03-04 | Astute Medical, Inc. | Assays for timp2 having improved performance in biological samples |
| US9822172B2 (en) | 2013-11-06 | 2017-11-21 | Astute Medical, Inc. | Assays for IGFBP7 having improved performance in biological samples |
| US10300108B2 (en) | 2013-12-03 | 2019-05-28 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US11243202B2 (en) | 2015-04-09 | 2022-02-08 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP3465201A4 (en) | 2016-06-06 | 2020-08-26 | Astute Medical, Inc. | MANAGEMENT OF ACUTE KIDNEY DAMAGE USING INSULINOMIMETIC GROWTH FACTOR BINDING PROTEIN 7 AND TISSUE METALLOPROTEINASE 2 INHIBITOR |
| CN110352073A (zh) | 2016-10-28 | 2019-10-18 | 机敏医药股份有限公司 | 针对timp-2的抗体用于改善肾功能的用途 |
| US11346846B2 (en) | 2017-02-06 | 2022-05-31 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US11718682B2 (en) | 2017-04-05 | 2023-08-08 | Astute Medical, Inc. | Assays for TIMP2 having improved performance in biological samples |
| WO2018208684A1 (en) | 2017-05-07 | 2018-11-15 | Astute Medical, Inc. | Use of insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinase 2 in the management of renal replacement therapy |
-
2009
- 2009-10-21 NZ NZ607703A patent/NZ607703A/en not_active IP Right Cessation
- 2009-10-21 US US13/125,360 patent/US8778615B2/en active Active
- 2009-10-21 EP EP21192675.3A patent/EP3974836A1/en active Pending
- 2009-10-21 CN CN201610679757.7A patent/CN106370857A/zh active Pending
- 2009-10-21 CA CA2740788A patent/CA2740788C/en active Active
- 2009-10-21 CN CN201410485595.4A patent/CN104391115B/zh not_active Expired - Fee Related
- 2009-10-21 NZ NZ592358A patent/NZ592358A/xx not_active IP Right Cessation
- 2009-10-21 EP EP20198819.3A patent/EP3783363A1/en not_active Withdrawn
- 2009-10-21 NZ NZ628843A patent/NZ628843A/en not_active IP Right Cessation
- 2009-10-21 WO PCT/US2009/061561 patent/WO2010048346A1/en not_active Ceased
- 2009-10-21 MX MX2011004174A patent/MX2011004174A/es active IP Right Grant
- 2009-10-21 EP EP09822669A patent/EP2364444A4/en not_active Withdrawn
- 2009-10-21 CN CN201310576168.2A patent/CN103760359B/zh active Active
- 2009-10-21 CN CN201410485610.5A patent/CN104391116B/zh not_active Expired - Fee Related
- 2009-10-21 JP JP2011532354A patent/JP2012506537A/ja active Pending
- 2009-10-21 EP EP17174892.4A patent/EP3246707B1/en active Active
- 2009-10-21 CN CN200980149555.XA patent/CN102246035B/zh not_active Expired - Fee Related
- 2009-10-21 CN CN201410485543.7A patent/CN104399089B/zh not_active Expired - Fee Related
- 2009-10-21 AU AU2009308497A patent/AU2009308497B2/en active Active
- 2009-10-21 ES ES17174892T patent/ES2836218T3/es active Active
- 2009-10-21 KR KR1020117011445A patent/KR101760314B1/ko active Active
- 2009-10-21 BR BRPI0919640A patent/BRPI0919640A2/pt not_active IP Right Cessation
-
2014
- 2014-02-10 JP JP2014023208A patent/JP6247948B2/ja active Active
- 2014-07-09 US US14/327,513 patent/US10823733B2/en not_active Expired - Fee Related
-
2016
- 2016-10-06 JP JP2016197891A patent/JP6400651B2/ja not_active Expired - Fee Related
-
2018
- 2018-09-05 JP JP2018166435A patent/JP6580227B2/ja active Active
-
2020
- 2020-10-30 US US17/085,566 patent/US11754566B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11754566B2 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| US9470695B2 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| EP2324354B1 (en) | Methods for prognosis of acute renal failure | |
| AU2009285550B2 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| AU2009308375B2 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| AU2010210540B2 (en) | Methods and compositions for diagnosis and prognosis of renal injury and failure | |
| CA2743253A1 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| US20120052512A1 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| CA2751424A1 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| CA2770393A1 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| CA2779902A1 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| AU2014271124A1 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| AU2013202655B2 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| CA2880793A1 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| AU2015230791A1 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| AU2015200266A1 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| AU2015203434A1 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
| CA2899658A1 (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20140919 |
|
| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 15TH ANNIV.) - SMALL Year of fee payment: 15 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20241011 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20241011 |
|
| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 16TH ANNIV.) - SMALL Year of fee payment: 16 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20251017 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20251017 |