CA2737645A1 - Compounds which selectively modulate the cb2 receptor - Google Patents
Compounds which selectively modulate the cb2 receptor Download PDFInfo
- Publication number
- CA2737645A1 CA2737645A1 CA2737645A CA2737645A CA2737645A1 CA 2737645 A1 CA2737645 A1 CA 2737645A1 CA 2737645 A CA2737645 A CA 2737645A CA 2737645 A CA2737645 A CA 2737645A CA 2737645 A1 CA2737645 A1 CA 2737645A1
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- CA
- Canada
- Prior art keywords
- alkyl
- methyl
- isomer
- mmol
- mhz
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/14—Nitrogen atoms
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10007708P | 2008-09-25 | 2008-09-25 | |
US61/100,077 | 2008-09-25 | ||
PCT/US2009/057777 WO2010036631A2 (en) | 2008-09-25 | 2009-09-22 | Compounds which selectively modulate the cb2 receptor |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2737645A1 true CA2737645A1 (en) | 2010-04-01 |
Family
ID=41698020
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2737639A Abandoned CA2737639A1 (en) | 2008-09-25 | 2009-09-22 | Compounds which selectively modulate the cb2 receptor |
CA2737645A Abandoned CA2737645A1 (en) | 2008-09-25 | 2009-09-22 | Compounds which selectively modulate the cb2 receptor |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2737639A Abandoned CA2737639A1 (en) | 2008-09-25 | 2009-09-22 | Compounds which selectively modulate the cb2 receptor |
Country Status (24)
Country | Link |
---|---|
US (4) | US8372874B2 (pt-PT) |
EP (2) | EP2342199B1 (pt-PT) |
JP (2) | JP4928650B2 (pt-PT) |
KR (2) | KR20110063438A (pt-PT) |
CN (2) | CN102164916A (pt-PT) |
AP (1) | AP2011005674A0 (pt-PT) |
AR (2) | AR073687A1 (pt-PT) |
AU (2) | AU2009296838A1 (pt-PT) |
BR (2) | BRPI0919024A2 (pt-PT) |
CA (2) | CA2737639A1 (pt-PT) |
CL (2) | CL2011000663A1 (pt-PT) |
CO (1) | CO6361912A2 (pt-PT) |
EA (1) | EA201100523A1 (pt-PT) |
EC (1) | ECSP11010931A (pt-PT) |
IL (2) | IL210433A0 (pt-PT) |
MA (1) | MA32654B1 (pt-PT) |
MX (1) | MX2011002904A (pt-PT) |
NZ (1) | NZ591111A (pt-PT) |
PE (1) | PE20110397A1 (pt-PT) |
RU (1) | RU2011116111A (pt-PT) |
TW (2) | TW201018677A (pt-PT) |
UY (1) | UY32139A (pt-PT) |
WO (2) | WO2010036630A2 (pt-PT) |
ZA (1) | ZA201100483B (pt-PT) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2081905B1 (en) | 2006-07-28 | 2012-09-12 | Boehringer Ingelheim International GmbH | Sulfonyl compounds which modulate the cb2 receptor |
JP5030114B2 (ja) | 2006-09-25 | 2012-09-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cb2受容体をモジュレートする化合物 |
WO2008048914A1 (en) * | 2006-10-17 | 2008-04-24 | Boehringer Ingelheim International Gmbh | Polycyclic compounds which modulate the cb2 receptor |
US8173638B2 (en) * | 2006-11-21 | 2012-05-08 | Boehringer Ingelheim International Gmbh | Compounds which modulate the CB2 receptor |
EP2215080A1 (en) * | 2007-10-25 | 2010-08-11 | Boehringer Ingelheim International GmbH | Diazepane compounds which modulate the cb2 receptor |
EP2217565B1 (en) * | 2007-11-07 | 2013-05-22 | Boehringer Ingelheim International GmbH | Compounds which modulate the cb2 receptor |
CA2716515A1 (en) * | 2008-02-21 | 2009-08-27 | Boehringer Ingelheim International Gmbh | Amine and ether compounds which modulate the cb2 receptor |
US8178568B2 (en) | 2008-07-10 | 2012-05-15 | Boehringer Ingelheim International Gmbh | Sulfone compounds which modulate the CB2 receptor |
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- 2009-09-22 KR KR1020117004615A patent/KR20110063438A/ko not_active Application Discontinuation
- 2009-09-22 KR KR1020117006824A patent/KR20110063485A/ko not_active Application Discontinuation
- 2009-09-22 CA CA2737639A patent/CA2737639A1/en not_active Abandoned
- 2009-09-22 EP EP09792817.0A patent/EP2342199B1/en active Active
- 2009-09-22 AU AU2009296838A patent/AU2009296838A1/en not_active Abandoned
- 2009-09-22 EP EP09792816A patent/EP2342200B1/en active Active
- 2009-09-22 EA EA201100523A patent/EA201100523A1/ru unknown
- 2009-09-22 PE PE2011000669A patent/PE20110397A1/es not_active Application Discontinuation
- 2009-09-22 CN CN2009801374019A patent/CN102164916A/zh active Pending
- 2009-09-22 US US12/564,133 patent/US8372874B2/en active Active
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