CA2715501A1 - Blocage des metastases de cellules cancereuses et nouvelles compositions a cet effet - Google Patents

Blocage des metastases de cellules cancereuses et nouvelles compositions a cet effet Download PDF

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Publication number
CA2715501A1
CA2715501A1 CA2715501A CA2715501A CA2715501A1 CA 2715501 A1 CA2715501 A1 CA 2715501A1 CA 2715501 A CA2715501 A CA 2715501A CA 2715501 A CA2715501 A CA 2715501A CA 2715501 A1 CA2715501 A1 CA 2715501A1
Authority
CA
Canada
Prior art keywords
beta
alpha
fwdarw
angeloyl
alkanoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2715501A
Other languages
English (en)
Inventor
Pui-Kwong Chan
May Sung Mak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pacific Arrow Ltd
Original Assignee
Pacific Arrow Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2008/002086 external-priority patent/WO2008133766A1/fr
Priority claimed from US12/344,682 external-priority patent/US8841265B2/en
Application filed by Pacific Arrow Ltd filed Critical Pacific Arrow Ltd
Publication of CA2715501A1 publication Critical patent/CA2715501A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)
CA2715501A 2008-02-15 2009-02-13 Blocage des metastases de cellules cancereuses et nouvelles compositions a cet effet Abandoned CA2715501A1 (fr)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
USPCT/US2008/002086 2008-02-15
PCT/US2008/002086 WO2008133766A1 (fr) 2007-02-16 2008-02-15 Blocage de la migration ou de la metastase des cellules cancereuses par la modification de proteines d'adhesion et utilisations de nouveaux composes associes
US3827708P 2008-03-20 2008-03-20
US61/038,277 2008-03-20
US5430808P 2008-05-19 2008-05-19
US61/054,308 2008-05-19
US12/344,682 US8841265B2 (en) 2003-10-09 2008-12-29 Composition comprising triterpene saponins and compounds with angeloyl functional group, methods for preparing same and uses thereof
US12/344,682 2008-12-29
PCT/US2009/034115 WO2009117196A1 (fr) 2008-02-15 2009-02-13 Blocage des métastases de cellules cancéreuses et nouvelles compositions à cet effet

Publications (1)

Publication Number Publication Date
CA2715501A1 true CA2715501A1 (fr) 2009-09-24

Family

ID=41091216

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2715501A Abandoned CA2715501A1 (fr) 2008-02-15 2009-02-13 Blocage des metastases de cellules cancereuses et nouvelles compositions a cet effet

Country Status (5)

Country Link
EP (1) EP2254899A4 (fr)
CN (1) CN101998964B (fr)
AU (1) AU2009226063A1 (fr)
CA (1) CA2715501A1 (fr)
WO (1) WO2009117196A1 (fr)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201136604A (en) * 2009-12-14 2011-11-01 Oncotherapy Science Inc TMEM22 peptides and vaccines including the same
CA3115431A1 (fr) * 2010-07-16 2012-01-19 Pacific Arrow Limited Nouveaux composes pour traiter le cancer et d'autres maladies
KR101873607B1 (ko) * 2010-07-16 2018-07-02 퍼시픽 애로우 리미티드 암 및 다른 질환들을 치료하기 위한 화합물
GB201016902D0 (en) 2010-10-07 2010-11-24 Chamberlain Luke A boiler assembly comprising a removable boiler unit
US9145559B2 (en) 2011-10-27 2015-09-29 Yeda Research And Development Co. Ltd. Methods of treating cancer
CN102851388B (zh) * 2012-09-29 2014-03-19 山东大学齐鲁医院 一种用于鉴别卵巢癌易感性的分子标记、试剂盒及其鉴别方法
CN102864234B (zh) * 2012-09-29 2014-03-19 山东大学齐鲁医院 一种用于鉴别卵巢癌易感性的分子标记
CN104062432B (zh) * 2013-03-22 2016-01-20 中山大学 ang2在制备ECTC血管类型肝癌诊断试剂及治疗药物中的应用
CN106535903A (zh) * 2014-04-10 2017-03-22 中央研究院 以pdia4蛋白作为糖尿病的诊断、监测及治疗的目标
CN103992236B (zh) * 2014-04-29 2016-05-18 于非 一种新型靶向性抗肿瘤药物及其制备方法与应用
CN105467127B (zh) * 2015-03-23 2017-06-06 复旦大学 一种人结肠癌蛋白质标志物col6a3的应用方法及其检测试剂盒
CN109803978B (zh) * 2016-09-07 2022-07-01 武汉华大吉诺因生物科技有限公司 多肽及其应用
WO2018219342A1 (fr) * 2017-06-01 2018-12-06 立森印迹诊断技术有限公司 Modèle gradué de gènes imprimés et méthode et application de diagnostic
CN107312855B (zh) * 2017-07-24 2020-12-25 青岛泱深生物医药有限公司 一种与喉鳞癌相关的基因及其应用
CN107543926A (zh) * 2017-08-25 2018-01-05 复旦大学附属金山医院 一种新的诊断乳腺浸润性导管癌的应用
TW201919644A (zh) * 2017-09-29 2019-06-01 台灣浩鼎生技股份有限公司 治療血癌的方法
CN108103194B (zh) * 2017-12-27 2021-05-18 中国医学科学院药用植物研究所 一种抑制胃癌细胞mgc-803的靶点及其应用
CN108220421B (zh) * 2018-01-05 2019-04-05 智海基因科技南京有限公司 自身免疫性肝炎的诊断试剂盒及相关基因在制备该试剂盒中的应用
CN110272997B (zh) * 2018-03-14 2023-04-28 华中科技大学同济医学院附属同济医院 一种C/EBPβ基因或者蛋白的用途
CN108728539A (zh) * 2018-06-05 2018-11-02 浙江大学 一种HoxD10基因在胃癌中的应用
CN108840923B (zh) * 2018-06-22 2021-08-03 上海交通大学医学院附属仁济医院 一种靶向pd-l1的多肽及其应用
CN108642181B (zh) * 2018-06-25 2021-09-10 遵义医科大学附属医院 长链非编码rna slc25a25-as1的应用
CN111217900A (zh) * 2018-11-27 2020-06-02 上海交通大学 一种血管新生的转录调控因子及其用途
CN111289749B (zh) * 2018-12-10 2023-04-14 北京蛋白质组研究中心 C型1类尼曼-匹克蛋白检测物在制备筛查肝细胞癌产品中的应用
CN109402125A (zh) * 2018-12-11 2019-03-01 宁夏医科大学总医院 一种环状RNA hsa_circTGFBI_007及其特异性扩增引物和应用
CN109402119A (zh) * 2018-12-11 2019-03-01 宁夏医科大学总医院 一种环状RNA hsa_circTGFBI_001及其特异性扩增引物和应用
CN110672848A (zh) * 2019-10-25 2020-01-10 四川大学华西医院 Apeh自身抗体检测试剂在制备肺癌筛查试剂盒中的用途
CN111153956B (zh) * 2019-12-06 2020-12-11 江苏一片叶高新科技有限公司 一种茶皂苷类化合物、制备方法及应用
CN110938630B (zh) * 2019-12-20 2023-07-28 中国人民解放军第四军医大学 人b3gnt5基因的用途及相关产品
CN111166769B (zh) * 2020-03-18 2022-01-11 山东大学 真皮成纤维细胞在治疗黑色素瘤中的应用
CN111979328B (zh) * 2020-09-07 2022-10-14 复旦大学附属中山医院 一种预测肝癌肺转移的生物标志物及其应用
CN112011620B (zh) * 2020-09-23 2021-04-27 山东大学第二医院 circ-SLC38A1作为靶点在抑制膀胱癌细胞药物中的应用
CN112481373B (zh) * 2020-12-21 2022-01-28 华北理工大学 一种用于孤独症辅助诊断的circRNA检测试剂盒
CN114015689B (zh) * 2021-10-26 2024-06-07 江苏大学 一种特异性抑制GOS2基因表达的shRNA序列及其应用
CN114984187B (zh) * 2022-07-20 2024-07-26 南通大学 跨膜蛋白Tmem63b在制备治疗周围神经脱髓鞘类疾病的药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69918166T2 (de) * 1998-12-22 2005-07-07 Janssen Pharmaceutica N.V. Antiprotozoale saponine
US8614197B2 (en) * 2003-10-09 2013-12-24 Pacific Arrow Limited Anti-tumor compounds with angeloyl groups

Also Published As

Publication number Publication date
EP2254899A4 (fr) 2012-05-30
WO2009117196A8 (fr) 2009-11-26
CN101998964A (zh) 2011-03-30
EP2254899A1 (fr) 2010-12-01
AU2009226063A1 (en) 2009-09-24
WO2009117196A1 (fr) 2009-09-24
CN101998964B (zh) 2015-05-06

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Legal Events

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Effective date: 20150213