CA2707060A1 - Polysaccharide gel compositions and methods for sustained delivery of drugs - Google Patents
Polysaccharide gel compositions and methods for sustained delivery of drugs Download PDFInfo
- Publication number
- CA2707060A1 CA2707060A1 CA2707060A CA2707060A CA2707060A1 CA 2707060 A1 CA2707060 A1 CA 2707060A1 CA 2707060 A CA2707060 A CA 2707060A CA 2707060 A CA2707060 A CA 2707060A CA 2707060 A1 CA2707060 A1 CA 2707060A1
- Authority
- CA
- Canada
- Prior art keywords
- polysaccharide
- hyaluronic acid
- sulfate
- biocompatible
- gel composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 150000004676 glycans Chemical class 0.000 title claims abstract description 103
- 229920001282 polysaccharide Polymers 0.000 title claims abstract description 103
- 239000005017 polysaccharide Substances 0.000 title claims abstract description 103
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- 238000000034 method Methods 0.000 title claims abstract description 48
- 229940079593 drug Drugs 0.000 title claims description 41
- 239000003814 drug Substances 0.000 title claims description 41
- 230000002459 sustained effect Effects 0.000 title description 5
- 238000013268 sustained release Methods 0.000 claims abstract description 21
- 239000012730 sustained-release form Substances 0.000 claims abstract description 21
- 239000008194 pharmaceutical composition Substances 0.000 claims abstract description 12
- 201000010099 disease Diseases 0.000 claims abstract description 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 9
- 229920002674 hyaluronan Polymers 0.000 claims description 78
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 69
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- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 description 15
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| US60/991,524 | 2007-11-30 | ||
| US12/323,251 US20090143348A1 (en) | 2007-11-30 | 2008-11-25 | Polysaccharide gel compositions and methods for sustained delivery of drugs |
| US12/323,251 | 2008-11-25 | ||
| PCT/US2008/084841 WO2009073508A2 (en) | 2007-11-30 | 2008-11-26 | Polysaccharide gel compositions and methods for sustained delivery of drugs |
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| CA2707060A1 true CA2707060A1 (en) | 2009-06-11 |
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| CA2707060A Abandoned CA2707060A1 (en) | 2007-11-30 | 2008-11-26 | Polysaccharide gel compositions and methods for sustained delivery of drugs |
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| CA (1) | CA2707060A1 (https=) |
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-
2008
- 2008-11-25 US US12/323,251 patent/US20090143348A1/en not_active Abandoned
- 2008-11-26 RU RU2010125705/15A patent/RU2472487C2/ru not_active IP Right Cessation
- 2008-11-26 EP EP08858385A patent/EP2222714A2/en not_active Withdrawn
- 2008-11-26 WO PCT/US2008/084841 patent/WO2009073508A2/en not_active Ceased
- 2008-11-26 AU AU2008331491A patent/AU2008331491B2/en not_active Ceased
- 2008-11-26 CN CN2008801254883A patent/CN101925347A/zh active Pending
- 2008-11-26 CA CA2707060A patent/CA2707060A1/en not_active Abandoned
- 2008-11-26 BR BRPI0821080-2A2A patent/BRPI0821080A2/pt not_active Application Discontinuation
- 2008-11-26 KR KR1020107014424A patent/KR20100117058A/ko not_active Ceased
- 2008-11-26 JP JP2010536162A patent/JP2011505369A/ja active Pending
-
2013
- 2013-01-16 US US13/743,201 patent/US20130136780A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008331491A1 (en) | 2009-06-11 |
| RU2472487C2 (ru) | 2013-01-20 |
| JP2011505369A (ja) | 2011-02-24 |
| BRPI0821080A2 (pt) | 2014-09-30 |
| WO2009073508A3 (en) | 2009-08-13 |
| WO2009073508A2 (en) | 2009-06-11 |
| CN101925347A (zh) | 2010-12-22 |
| RU2010125705A (ru) | 2012-01-10 |
| US20130136780A1 (en) | 2013-05-30 |
| US20090143348A1 (en) | 2009-06-04 |
| EP2222714A2 (en) | 2010-09-01 |
| AU2008331491B2 (en) | 2013-08-22 |
| KR20100117058A (ko) | 2010-11-02 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20151126 |