CA2694139C - Albumin binding polypeptide compositions - Google Patents
Albumin binding polypeptide compositions Download PDFInfo
- Publication number
- CA2694139C CA2694139C CA2694139A CA2694139A CA2694139C CA 2694139 C CA2694139 C CA 2694139C CA 2694139 A CA2694139 A CA 2694139A CA 2694139 A CA2694139 A CA 2694139A CA 2694139 C CA2694139 C CA 2694139C
- Authority
- CA
- Canada
- Prior art keywords
- albumin binding
- seq
- binding polypeptide
- polypeptide according
- albumin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/52—Cytokines; Lymphokines; Interferons
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- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- Organic Chemistry (AREA)
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- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| EP07113533.9 | 2007-07-31 | ||
| EP07113533 | 2007-07-31 | ||
| PCT/EP2008/059389 WO2009016043A2 (en) | 2007-07-31 | 2008-07-17 | New albumin binding compositions, methods and uses |
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| WO2009016043A2 (en) * | 2007-07-31 | 2009-02-05 | Affibody Ab | New albumin binding compositions, methods and uses |
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| CN107686513A (zh) * | 2010-03-08 | 2018-02-13 | 通用电气医疗集团生物工艺研发股份公司 | 免疫球蛋白G Fc区结合多肽 |
| WO2011136361A1 (ja) * | 2010-04-30 | 2011-11-03 | 株式会社 三和化学研究所 | 生理活性物質等の生体内安定性向上のためのペプチド及び生体内安定性が向上した生理活性物質 |
| EP2590993B1 (en) * | 2010-07-09 | 2015-05-06 | Affibody AB | Polypeptides |
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| CN106986940A (zh) | 2010-09-28 | 2017-07-28 | 艾米琳制药有限责任公司 | 具有增强的作用持续时间的工程化多肽 |
| EA032917B1 (ru) * | 2010-09-28 | 2019-08-30 | Амилин Фармасьютикалс, Ллк | Сконструированные полипептиды, характеризующиеся увеличенной продолжительностью действия |
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| EP2729481B1 (en) * | 2011-07-08 | 2018-10-17 | Amylin Pharmaceuticals, LLC | Engineered polypeptides having enhanced duration of action with reduced immunogenicity |
| CN103957926B (zh) * | 2011-07-08 | 2018-07-03 | 安米林药品有限责任公司 | 具有增强的作用持续时间和降低的免疫原性的工程改造的多肽 |
| DK2817329T3 (en) | 2012-02-20 | 2019-04-01 | Swedish Orphan Biovitrum Ab Publ | Polypeptides Binding to Human Complement Component C5. |
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| JP2020033372A (ja) * | 2012-03-28 | 2020-03-05 | アフィボディ・アーベー | 経口投与 |
| EP2844269A4 (en) * | 2012-03-28 | 2016-01-06 | Amylin Pharmaceuticals Llc | TRANSMUCOSAL ADMINISTRATION OF MANIPULATED POLYPEPTIDES |
| BR112014029409B1 (pt) | 2012-05-25 | 2022-11-29 | Janssen Biotech, Inc | Domínio de ligação a albumina isolado não natural, método para produção do mesmo, polinucleotídeo isolado, vetor isolado, célula hospedeira isolada, proteína de fusão e composição farmacêutica |
| KR102123457B1 (ko) * | 2012-09-25 | 2020-06-16 | 애피바디 에이비 | 알부민 결합 폴리펩타이드 |
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| EP2912051B1 (en) * | 2012-10-25 | 2018-04-18 | Affibody AB | Method for the separation of proteins containing an albumin-binding domain |
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| HK1218534A1 (zh) * | 2013-03-14 | 2017-02-24 | 多伦多大学管理委员会 | 支架化肽文库以及其制备和筛选方法 |
| SG11201505856TA (en) | 2013-03-14 | 2015-08-28 | Daiichi Sankyo Co Ltd | Novel binding proteins for pcsk9 |
| EP2970406B1 (en) | 2013-03-15 | 2017-12-13 | Affibody AB | New polypeptides |
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| JP6767865B2 (ja) | 2013-08-28 | 2020-10-14 | スウェディッシュ・オーファン・バイオヴィトラム・アーベー（ペーウーベーエル） | ヒト補体ｃ５に結合する安定なポリペプチド |
| MY176200A (en) | 2013-08-28 | 2020-07-24 | Affibody Ab | Binding polypeptides having a mutated scaffold |
| JP6509867B2 (ja) | 2013-08-30 | 2019-05-08 | アルモ・バイオサイエンシーズ・インコーポレイテッド | 疾患及び障害を治療するためにインターロイキン−１０を使用する方法 |
| WO2015070060A1 (en) | 2013-11-11 | 2015-05-14 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
| EP3083675B1 (en) | 2013-12-20 | 2018-03-07 | Affibody AB | Engineered albumin binding polypeptide |
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| LT3193930T (lt) | 2014-09-17 | 2019-10-25 | Affibody Ab | Nauji polipeptidai |
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| ES2941234T3 (es) | 2014-10-22 | 2023-05-19 | Armo Biosciences Inc | Métodos de uso de la interleucina-10 para el tratamiento de enfermedades y trastornos |
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| WO2017210476A1 (en) | 2016-06-01 | 2017-12-07 | Duke University | Nonfouling biosensors |
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| CN107952080A (zh) * | 2016-10-14 | 2018-04-24 | 中国科学院过程工程研究所 | 一种肿瘤靶向多肽-药物偶联衍生物、其制备方法及应用 |
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| US11554097B2 (en) | 2017-05-15 | 2023-01-17 | Duke University | Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents |
| US11680083B2 (en) | 2017-06-30 | 2023-06-20 | Duke University | Order and disorder as a design principle for stimuli-responsive biopolymer networks |
| US11077199B2 (en) * | 2017-08-09 | 2021-08-03 | Massachusetts Institute Of Technology | Albumin binding peptide conjugates and methods thereof |
| US20200239575A1 (en) * | 2017-10-06 | 2020-07-30 | University Of Utah Research Foundation | A fusion protein for targeted therapy of autoimmune disease |
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| WO2019147954A1 (en) * | 2018-01-26 | 2019-08-01 | Duke University | Albumin binding peptide-drug (aibiped) conjugates and methods of making and using same |
| WO2019175176A1 (en) | 2018-03-13 | 2019-09-19 | Affibody Ab | Polypeptides based on a novel scaffold |
| US12257308B2 (en) | 2018-04-30 | 2025-03-25 | Duke University | Stimuli-responsive PEG-like polymer-based drug delivery platform |
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| EP3930687A4 (en) | 2019-02-25 | 2023-06-07 | The University of Chicago | METHODS AND COMPOSITIONS FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE CONDITIONS USING ECM AFFINITY PEPTIDES LINKED TO ANTI-INFLAMMATORY AGENTS |
| US12441772B2 (en) | 2019-06-04 | 2025-10-14 | Molecular Partners Ag | Designed ankyrin repeat domain with improved stability |
| US11512314B2 (en) | 2019-07-12 | 2022-11-29 | Duke University | Amphiphilic polynucleotides |
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| JP2022546525A (ja) | 2019-09-02 | 2022-11-04 | ビオテスト・アクチエンゲゼルシャフト | 延長された半減期を有する第ｖｉｉｉ因子タンパク質 |
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| WO2021165226A1 (en) | 2020-02-17 | 2021-08-26 | Biotest Ag | Subcutaneous administration of factor viii |
| EP3878515A1 (en) * | 2020-03-09 | 2021-09-15 | Hober Biotech AB | Therapeutic agent targeting her2 |
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| JP2023554258A (ja) | 2020-12-21 | 2023-12-27 | アフィボディ アクティエボラーグ | 新規のポリペプチド |
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| KR20240139058A (ko) | 2022-02-08 | 2024-09-20 | 애피바디 에이비 | 흉선 기질 림포포이에틴에 결합하는 단백질 z 변이체 및 이의 의학적 용도 |
| US12139502B2 (en) | 2022-05-18 | 2024-11-12 | Protomer Technologies Inc. | Aromatic boron-containing compounds and related insulin analogs |
| WO2024034685A1 (ja) | 2022-08-10 | 2024-02-15 | 興和株式会社 | アフィボディミセル薬物複合体 |
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| FR2718452B1 (fr) * | 1994-04-06 | 1996-06-28 | Pf Medicament | Elément d'immunogène, agent immunogène, composition pharmaceutique et procédé de préparation. |
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| ES2346178T1 (es) | 2010-10-13 |
| ES2346178T3 (es) | 2015-11-02 |
| CN104710518A (zh) | 2015-06-17 |
| CA2694139A1 (en) | 2009-02-05 |
| US10118949B2 (en) | 2018-11-06 |
| AU2008281913B2 (en) | 2013-11-07 |
| DK2190863T3 (en) | 2015-11-30 |
| CN101765608B (zh) | 2015-03-11 |
| US20100273979A1 (en) | 2010-10-28 |
| EP2190863B1 (en) | 2015-09-02 |
| WO2009016043A2 (en) | 2009-02-05 |
| EP2546261A3 (en) | 2013-08-14 |
| AU2008281913A1 (en) | 2009-02-05 |
| CN101765608A (zh) | 2010-06-30 |
| WO2009016043A3 (en) | 2009-06-04 |
| US20150158916A1 (en) | 2015-06-11 |
| JP2010534486A (ja) | 2010-11-11 |
| DE08786222T1 (de) | 2010-11-25 |
| JP5718638B2 (ja) | 2015-05-13 |
| US8937153B2 (en) | 2015-01-20 |
| EP2546261A2 (en) | 2013-01-16 |
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