CA2692553A1 - Hydrogel a gelification rapide biocompatible et procede de preparation connexe de pulverisateur - Google Patents

Hydrogel a gelification rapide biocompatible et procede de preparation connexe de pulverisateur Download PDF

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Publication number
CA2692553A1
CA2692553A1 CA 2692553 CA2692553A CA2692553A1 CA 2692553 A1 CA2692553 A1 CA 2692553A1 CA 2692553 CA2692553 CA 2692553 CA 2692553 A CA2692553 A CA 2692553A CA 2692553 A1 CA2692553 A1 CA 2692553A1
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Prior art keywords
biocompatible
solution
component
preparation
rapid
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CA 2692553
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CA2692553C (fr
Inventor
Xiaozheng Shu
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Bioregen Biomedical Changzhou Co Ltd
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Bioregen Biomedical (Changzhou) Co., Ltd.
Xiaozheng Shu
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Publication of CA2692553A1 publication Critical patent/CA2692553A1/fr
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G75/00—Macromolecular compounds obtained by reactions forming a linkage containing sulfur with or without nitrogen, oxygen, or carbon in the main chain of the macromolecule
    • C08G75/02—Polythioethers
    • C08G75/04—Polythioethers from mercapto compounds or metallic derivatives thereof
    • C08G75/045—Polythioethers from mercapto compounds or metallic derivatives thereof from mercapto compounds and unsaturated compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G75/00—Macromolecular compounds obtained by reactions forming a linkage containing sulfur with or without nitrogen, oxygen, or carbon in the main chain of the macromolecule
    • C08G75/12—Polythioether-ethers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Materials For Medical Uses (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
CA2692553A 2007-07-06 2008-06-10 Hydrogel a gelification rapide biocompatible et procede de preparation connexe de pulverisateur Active CA2692553C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2007100939310A CN101338036B (zh) 2007-07-06 2007-07-06 生物相容快速凝胶化水凝胶及其喷雾剂的制备方法
CN200710093931.0 2007-07-06
PCT/CN2008/001120 WO2009006780A1 (fr) 2007-07-06 2008-06-10 Procédé pour la formation d'un hydrogel biocompatible à gélification rapide et préparation d'un agent de pulvérisation

Publications (2)

Publication Number Publication Date
CA2692553A1 true CA2692553A1 (fr) 2009-01-15
CA2692553C CA2692553C (fr) 2013-09-03

Family

ID=40212212

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2692553A Active CA2692553C (fr) 2007-07-06 2008-06-10 Hydrogel a gelification rapide biocompatible et procede de preparation connexe de pulverisateur

Country Status (7)

Country Link
US (1) US8647670B2 (fr)
EP (1) EP2177236B1 (fr)
JP (1) JP5465172B2 (fr)
CN (1) CN101338036B (fr)
AU (1) AU2008274807B2 (fr)
CA (1) CA2692553C (fr)
WO (1) WO2009006780A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
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US10398647B2 (en) 2016-10-21 2019-09-03 Industrial Technology Research Institute Hydrogel compositions and drug delivery systems comprising the same
US20220144990A1 (en) * 2013-11-08 2022-05-12 Terumo Corporation Polymer particles

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CN102049067A (zh) * 2009-11-10 2011-05-11 清华大学 一种可原位交联的高分子水凝胶玻璃体替代材料
CA2730598C (fr) * 2010-03-16 2018-03-13 Confluent Surgical, Inc. Modulation de la vitesse de liberation de medicaments en controlant la transition du ph dans des hydrogels
CN102399295B (zh) 2010-09-09 2013-11-06 常州百瑞吉生物医药有限公司 低巯基化改性度生物相容高分子巯基化衍生物及其交联材料和用途
KR101913874B1 (ko) * 2010-11-10 2018-10-31 인리젠 장기 확대를 위한 주사가능 제제
JP6120778B2 (ja) * 2011-02-03 2017-04-26 ノースイースタン ユニヴァーシティ 生物学的材料の極めて特異的な捕獲および遊離のための方法および組成物
CA2833739A1 (fr) * 2011-04-20 2012-10-26 Carbylan Biosurgery, Inc. Compositions de formation de gel in situ
US9592251B2 (en) * 2011-06-16 2017-03-14 The Hong Kong University Of Science And Technology Multi-vinylsulfone containing molecule
CN102952278A (zh) * 2011-08-23 2013-03-06 北京大学人民医院 一种用于眼内填充的原位交联水凝胶及其制备方法与应用
US9267009B2 (en) 2011-09-01 2016-02-23 Aspen Research Corporation Methods and systems of graft polymerization on a functionalized substrate
CN102517211B (zh) * 2011-12-08 2013-11-06 西安交通大学 一种可快速解离型三维细胞培养载体及制备方法
KR101444877B1 (ko) 2011-12-30 2014-10-01 주식회사 삼양바이오팜 감마폴리글루탐산으로 구성된 현장 가교 수화겔 및 그의 제조 방법
CN103087218B (zh) * 2011-12-30 2016-01-20 北京大学 直链形肝素修饰的生物型人造血管
CN103804697B (zh) * 2012-11-09 2016-02-03 山东福瑞达生物科技有限公司 一种聚谷氨酸水凝胶的制备方法及其在复合肥中的应用
KR101623521B1 (ko) * 2013-08-05 2016-05-24 한국과학기술연구원 siRNA의 종양 표적화된 전달을 위한 젤라틴 기반 나노입자 복합체 및 그 제조방법
US20160206562A1 (en) * 2013-08-21 2016-07-21 Nrl Pharma, Inc. Method for producing microparticles
CN103497355B (zh) * 2013-09-03 2015-11-04 臧洪瑞 胺类化合物交联剂及其在水凝胶制备方法中的应用
CN103665400B (zh) * 2013-11-12 2016-01-13 张家界本草科技有限公司 白芨止血凝胶的制备方法及应用
CN103613686B (zh) * 2013-11-12 2015-08-19 广州恩轲肽医药科技有限公司 巯基化透明质酸的制备方法及其应用
CN103665397A (zh) * 2013-11-12 2014-03-26 广州市一杰医药科技有限公司 水凝胶的制备方法及应用
US10739338B2 (en) 2014-03-24 2020-08-11 Qt Holdings Corp Shaped articles including hydrogels and methods of manufacture and use thereof
JPWO2015147147A1 (ja) * 2014-03-26 2017-04-13 国立大学法人北海道大学 生物学的試料をハイドロゲルで高速固定する方法及びそのための装置
KR20170136493A (ko) * 2014-12-24 2017-12-11 로레알 광 활성화된 하이드로겔
WO2016133887A1 (fr) * 2015-02-16 2016-08-25 The University Of Akron Matériau hybride tissu décellularisé/nanofibres/hydrogel permettant d'optimiser la régénération tissulaire
CN104906625A (zh) * 2015-05-22 2015-09-16 苏州市贝克生物科技有限公司 一种医用水凝胶的制备方法
CN104874014A (zh) * 2015-05-22 2015-09-02 苏州市贝克生物科技有限公司 一种医用止血封堵敷料的制备方法
CN104892962B (zh) * 2015-06-05 2017-12-08 四川大学 一种巯基/二硫键可控自交联透明质酸水凝胶的制备方法及其应用
US9790467B2 (en) 2015-09-22 2017-10-17 Qt Holdings Corp Methods and compositions for activation or expansion of T lymphocytes
CN105906824A (zh) * 2016-01-13 2016-08-31 上海其胜生物制剂有限公司 一种可注射原位自组装透明质酸钠水凝胶的制备方法
CN105885064A (zh) * 2016-04-18 2016-08-24 北京化工大学 一种增韧型聚乙烯醇复合水凝胶及其应用
AU2017295715B2 (en) 2016-07-13 2022-03-17 Massachusetts Eye And Ear Infirmary Methods and polymer compositions for treating retinal detachment and other ocular disorders
CN108451673A (zh) * 2017-02-20 2018-08-28 中国科学院沈阳自动化研究所 一种椎间融合器材质结构
CN107625992B (zh) * 2017-10-01 2020-05-08 山东朱氏堂医疗器械有限公司 一种可溶性敷料及其制备方法
CN107929804A (zh) * 2017-12-26 2018-04-20 常州百瑞吉生物医药有限公司 改性明胶基复合海绵及其制备方法和用途
CN109337095A (zh) * 2018-09-21 2019-02-15 杭州协合医疗用品有限公司 一种交联透明质酸凝胶的制备方法及所制备的交联透明质酸凝胶
CN110755365B (zh) * 2019-06-19 2020-12-08 江苏拓弘康恒医药有限公司 基于间充质干细胞外泌体的水凝胶及其喷雾剂的制备方法
CN110279610B (zh) 2019-06-26 2021-06-11 常州百瑞吉生物医药有限公司 一种透明质酸皮肤保护组合物及其制备方法和应用
CN110787325A (zh) * 2019-09-21 2020-02-14 常州百瑞吉生物医药有限公司 用于预防腹（盆）腔术后组织粘连的二硫键交联透明质酸凝胶及其制备方法
CN112812329B (zh) * 2019-11-18 2023-06-16 孛朗孚(杭州)生物科技有限公司 巯基改性高分子化合物的水凝胶及其制备方法和用途
CN111265479A (zh) * 2020-03-10 2020-06-12 中山市天图精细化工有限公司 一种冷镇气雾剂贴片及其制备方法
CN111704730B (zh) * 2020-07-01 2023-03-03 王萌燕 一种胃内超吸水凝胶初品及其制备方法、胃内超吸水凝胶及其制备方法和减重组合物
CN112062946B (zh) * 2020-08-07 2022-09-20 广东工业大学 一种基于硼酸酯键的双交联自修复水凝胶及其制备方法和应用
CN114618010A (zh) * 2020-12-09 2022-06-14 四川大学 一种具有多功能的角蛋白基水凝胶及其制备方法
CN112920425B (zh) * 2021-01-22 2023-05-23 华东数字医学工程研究院 医用水凝胶组合物，医用水凝胶及其制备方法
CN113024847B (zh) * 2021-03-19 2022-09-13 中国科学院宁波材料技术与工程研究所 一种天然多糖水凝胶在止血领域中的应用
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CN113929975B (zh) * 2021-11-25 2022-06-24 南开大学 壳聚糖-蛋白质水凝胶组合物、水凝胶、其制备方法及医疗用途
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Publication number Priority date Publication date Assignee Title
US20220144990A1 (en) * 2013-11-08 2022-05-12 Terumo Corporation Polymer particles
US10398647B2 (en) 2016-10-21 2019-09-03 Industrial Technology Research Institute Hydrogel compositions and drug delivery systems comprising the same

Also Published As

Publication number Publication date
JP2010532396A (ja) 2010-10-07
EP2177236A1 (fr) 2010-04-21
CN101338036B (zh) 2010-11-03
US20100144902A1 (en) 2010-06-10
AU2008274807B2 (en) 2014-05-08
US8647670B2 (en) 2014-02-11
WO2009006780A1 (fr) 2009-01-15
AU2008274807A1 (en) 2009-01-15
JP5465172B2 (ja) 2014-04-09
CA2692553C (fr) 2013-09-03
EP2177236B1 (fr) 2016-11-02
CN101338036A (zh) 2009-01-07
EP2177236A4 (fr) 2012-12-12

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