CA2679682C - Compositions and methods for enhancing the development of growing animals - Google Patents
Compositions and methods for enhancing the development of growing animals Download PDFInfo
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- CA2679682C CA2679682C CA2679682A CA2679682A CA2679682C CA 2679682 C CA2679682 C CA 2679682C CA 2679682 A CA2679682 A CA 2679682A CA 2679682 A CA2679682 A CA 2679682A CA 2679682 C CA2679682 C CA 2679682C
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Landscapes
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| US89117107P | 2007-02-22 | 2007-02-22 | |
| US60/891,171 | 2007-02-22 | ||
| PCT/US2008/054773 WO2008103939A1 (en) | 2007-02-22 | 2008-02-22 | Compositions and methods for enhancing the development of growing animals |
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| CA2679682A1 CA2679682A1 (en) | 2008-08-28 |
| CA2679682C true CA2679682C (en) | 2012-09-11 |
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| CA2679065A Expired - Fee Related CA2679065C (en) | 2007-02-22 | 2008-02-22 | Compositions and methods for enhancing neurologic development |
| CA2679008A Expired - Fee Related CA2679008C (en) | 2007-02-22 | 2008-02-22 | Compositions and methods for promoting bone development |
| CA2679215A Expired - Fee Related CA2679215C (en) | 2007-02-22 | 2008-02-22 | Compositions and methods for altering gene expression |
| CA2678938A Active CA2678938C (en) | 2007-02-22 | 2008-02-22 | Compositions and methods for enhancing immune system of felines |
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| CA2679215A Expired - Fee Related CA2679215C (en) | 2007-02-22 | 2008-02-22 | Compositions and methods for altering gene expression |
| CA2678938A Active CA2678938C (en) | 2007-02-22 | 2008-02-22 | Compositions and methods for enhancing immune system of felines |
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| DE602006015830D1 (de) * | 2005-08-25 | 2010-09-09 | Lilly Co Eli | Anti-il-23-antikörper |
| BRPI0807372A2 (pt) * | 2007-02-22 | 2014-05-06 | Hills Pet Nutrition Inc | Composição de ração de animal de estimação, e, método para intensificar o desenvolvimento neurológico de um felino. |
| WO2010068173A1 (en) * | 2008-12-12 | 2010-06-17 | Daniel Klamer | L-lysine for improving normal cognitive functions |
| CN107050401A (zh) * | 2009-12-29 | 2017-08-18 | 希尔氏宠物营养品公司 | 用于改善或预防炎性病况的包含姜的组合物 |
| WO2011143102A1 (en) * | 2010-05-12 | 2011-11-17 | Hill's Pet Nutrition, Inc. | Methods of diagnosis, control and prophylaxis of inflammation and mitigation of inflammatory conditions in felines |
| JP2014502165A (ja) * | 2010-12-20 | 2014-01-30 | ヒルズ・ペット・ニュートリシャン・インコーポレーテッド | 満腹応答を誘導するためのペットフード組成物 |
| EP2705844B1 (en) * | 2011-04-13 | 2019-05-22 | Ajinomoto Co., Inc. | Nutritional composition |
| US8828426B2 (en) | 2011-06-07 | 2014-09-09 | Zx Pharma, Llc | Multiparticulate L-carnitine compositions and related methods |
| CN104039823A (zh) | 2011-12-19 | 2014-09-10 | 希尔氏宠物营养品公司 | 用于诊断和治疗伴侣动物的甲状腺机能亢进的组合物和方法 |
| CN103315187B (zh) * | 2013-07-17 | 2014-11-05 | 江苏桂龙生物技术有限公司 | 一种预防宠物骨骼性疾病的饲料 |
| CN104026401B (zh) * | 2014-06-10 | 2016-04-27 | 务川县绿之源农业技术推广中心 | 一种小型幼犬粮 |
| JP6896220B2 (ja) * | 2014-10-30 | 2021-06-30 | 不二製油株式会社 | 長鎖多価不飽和脂肪酸含有油脂およびそれを含有する食品 |
| GB201522300D0 (en) * | 2015-12-17 | 2016-02-03 | Mars Inc | Puppy growth food product |
| US11617737B2 (en) | 2016-12-15 | 2023-04-04 | Société des Produits Nestlé S.A. | Compositions and methods that modulate vitamin D and bone mineral content in a companion animal |
| JP7206113B2 (ja) * | 2016-12-15 | 2023-01-17 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | 小型イヌ科動物用の組成物及び方法 |
| WO2018219877A1 (en) * | 2017-05-29 | 2018-12-06 | Nestec S.A. | Medium chain fatty acids for use in the prevention or treatment of cardiac enlargement and/or valvular heart disease |
| US20190240180A1 (en) * | 2018-02-08 | 2019-08-08 | Nestec Sa | Mct-based nutrition blend for providing health benefits in companion animals |
| CN108244374A (zh) * | 2018-02-27 | 2018-07-06 | 佛山市雷米高动物营养保健科技有限公司 | 猫用营养粉剂及其制备方法 |
| EP3917329A4 (en) * | 2019-02-01 | 2022-11-30 | Mars, Incorporated | CAT FOOD COMPOSITION |
| CN110537630A (zh) * | 2019-09-09 | 2019-12-06 | 天津农学院 | 1，2二硫戊环-3-戊酸的应用、幼犬鲜粮和延长幼犬鲜粮贮藏期的方法 |
| BR112022009857A2 (pt) * | 2019-12-19 | 2022-08-02 | Nestle Sa | Composições e métodos para fornecer um benefício de saúde a um animal em crescimento |
| US20230165281A1 (en) * | 2021-11-29 | 2023-06-01 | Société des Produits Nestlé S.A. | Methods and compositions for providing a health benefit in an animal |
| WO2023150389A1 (en) * | 2022-02-07 | 2023-08-10 | Cornell University | Compositions and methods for increasing dha availability |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4267195A (en) * | 1976-09-10 | 1981-05-12 | University Of Texas | Dog food flavors |
| US4130651A (en) * | 1978-03-31 | 1978-12-19 | American Cyanamid Company | Butamisole injectable formulations having improved margin of safety in dogs |
| JPH0625057B2 (ja) * | 1987-12-14 | 1994-04-06 | 日本油脂株式会社 | 骨形成促進剤 |
| JPH04166039A (ja) * | 1990-10-26 | 1992-06-11 | Hirotoshi Yokura | ペットフード |
| US5690988A (en) * | 1996-02-02 | 1997-11-25 | Colgate Palmolive Company | Pet food composition of improved palatability and a method of enhancing the palatability of a food composition |
| US5851573A (en) * | 1997-04-29 | 1998-12-22 | The Iams Company | Pet food composition for large breed puppies and method for promoting proper skeletal growth |
| US6156355A (en) * | 1998-11-02 | 2000-12-05 | Star-Kist Foods, Inc. | Breed-specific canine food formulations |
| GB2367489B (en) * | 2000-07-31 | 2005-02-09 | Mars Inc | Use of antioxidants |
| NZ527924A (en) * | 1999-01-29 | 2005-01-28 | Mars Uk Ltd | Antioxidant compositions and methods for companion animals |
| US6071544A (en) * | 1999-04-01 | 2000-06-06 | The Iams Company | Dietary compositions and method for promoting healthy weight loss cats |
| RU2001127578A (ru) * | 1999-05-27 | 2004-03-27 | Дзе ИАМС КОМПАНИ (US) | Способ и продукт для усиления иммунной ответной реакции у домашних животных, использующие комбинацию антиоксидантов |
| EG22407A (en) | 2000-02-17 | 2003-01-29 | Iams Company | Method for improving bone modeling and chondrocyte functioning in growing canines |
| GB2367487A (en) | 2000-10-04 | 2002-04-10 | John Kennedy Mcmillan | Tooth cleaner |
| ES2311482T3 (es) * | 2000-12-29 | 2009-02-16 | Martin Francis Gannon | Producto alimenticio para animales. |
| US6582752B2 (en) * | 2001-11-02 | 2003-06-24 | Nestec, Ltd | Methods and compositions for a gender specific diet for puppies |
| CA2487823A1 (en) * | 2002-07-12 | 2004-01-22 | The Iams Company | Synergistic effect of diet and human interaction on the behavior of dogs |
| WO2004008196A1 (ja) * | 2002-07-13 | 2004-01-22 | Autocloning Technology Ltd. | 偏光解析装置 |
| US20050271603A1 (en) | 2002-07-26 | 2005-12-08 | Stephanie Krammer | Compositions comprising lactoferrin |
| EP1619960A4 (en) * | 2003-03-07 | 2009-03-18 | Advanced Bionutrition Corp | FEED FORMULATION FOR LAND AND WATER RESIDENTS |
| US20070037885A1 (en) | 2003-04-25 | 2007-02-15 | Sandra Edwards | Biomass containing animal feed |
| ES2479944T3 (es) * | 2003-07-03 | 2014-07-25 | Hill's Pet Nutrition, Inc. | Composiciones y métodos para disminuir el deterioro ligado a la edad en las actividades mentales de los animales de compañía |
| JP2007525201A (ja) * | 2003-07-07 | 2007-09-06 | ヒルズ・ペット・ニュートリシャン・インコーポレーテッド | コンパニオンアニマルにおいて改良された酸化的状態を得るための組成物 |
| AU2004210599B2 (en) | 2003-09-12 | 2009-09-24 | Mars, Incorporated | Food product for hairball treatment |
| US8921422B2 (en) * | 2003-10-01 | 2014-12-30 | The Iams Company | Methods and kits for enhancing ability to learn in a puppy or kitten |
| US20050266051A1 (en) * | 2004-05-27 | 2005-12-01 | The Procter & Gamble Company | Pet food compositions and methods |
| CA2578634C (en) * | 2004-08-30 | 2016-06-14 | Hill's Pet Nutrition, Inc. | Genome-based diet design |
| CN1631207A (zh) | 2004-12-03 | 2005-06-29 | 王志文 | 能改善猫狗皮毛质量的不饱和脂肪酸饲料添加剂及饲料 |
| US8148325B2 (en) * | 2004-12-30 | 2012-04-03 | Hill's Pet Nutrition, Inc. | Methods for enhancing the quality of life of a senior animal |
| CA2592827C (en) * | 2004-12-30 | 2013-08-13 | Hill's Pet Nutrition, Inc. | Methods for enhancing the quality of life of a growing animal |
| JP2009510117A (ja) * | 2005-09-30 | 2009-03-12 | ネステク ソシエテ アノニム | 認知機能向上のための方法及び組成物 |
| BRPI0706448A2 (pt) * | 2006-01-10 | 2011-03-29 | Hills Pet Nutrition Inc | método, composição e kit para promover perda de gordura em um animal adulto, meio para comunicar informação sobre ou instruções para usar uma dieta, e, uso de lisina |
| AU2007282912A1 (en) | 2006-08-09 | 2008-02-14 | The Iams Company | Methods of improving bone health and muscle health |
| BRPI0807372A2 (pt) | 2007-02-22 | 2014-05-06 | Hills Pet Nutrition Inc | Composição de ração de animal de estimação, e, método para intensificar o desenvolvimento neurológico de um felino. |
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