CA2676413A1 - Diagnostic and therapeutic cyclooxygenase-2 binding ligands - Google Patents

Diagnostic and therapeutic cyclooxygenase-2 binding ligands Download PDF

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Publication number
CA2676413A1
CA2676413A1 CA002676413A CA2676413A CA2676413A1 CA 2676413 A1 CA2676413 A1 CA 2676413A1 CA 002676413 A CA002676413 A CA 002676413A CA 2676413 A CA2676413 A CA 2676413A CA 2676413 A1 CA2676413 A1 CA 2676413A1
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CA
Canada
Prior art keywords
hydroxyl
group
conjugate
metal
nitro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002676413A
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English (en)
French (fr)
Inventor
Carol P. Howard
Dennis A. Moore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt LLC
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Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2676413A1 publication Critical patent/CA2676413A1/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002676413A 2007-01-19 2008-01-17 Diagnostic and therapeutic cyclooxygenase-2 binding ligands Abandoned CA2676413A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88569007P 2007-01-19 2007-01-19
US60/885,690 2007-01-19
PCT/US2008/000631 WO2008091530A2 (en) 2007-01-19 2008-01-17 Diagnostic and therapeutic cyclooxygenase-2 binding ligands

Publications (1)

Publication Number Publication Date
CA2676413A1 true CA2676413A1 (en) 2008-07-31

Family

ID=39567925

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002676413A Abandoned CA2676413A1 (en) 2007-01-19 2008-01-17 Diagnostic and therapeutic cyclooxygenase-2 binding ligands

Country Status (6)

Country Link
US (1) US20100111858A1 (enExample)
EP (1) EP2114461A2 (enExample)
JP (1) JP2010516679A (enExample)
CN (1) CN101626787A (enExample)
CA (1) CA2676413A1 (enExample)
WO (1) WO2008091530A2 (enExample)

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CN107007571B (zh) * 2017-02-24 2020-08-21 福州市传染病医院 肿瘤微酸性敏感的铜-药物共配位自组装纳米粒及应用
WO2018204872A2 (en) 2017-05-05 2018-11-08 Fusion Pharmaceuticals Inc. Igf-1r monoclonal antibodies and uses thereof
MA48861A (fr) 2017-05-05 2020-04-01 Fusion Pharmaceuticals Inc Améliorations pharmacocinétiques de chélates bifonctionnels et leurs utilisations
WO2019182395A1 (ko) * 2018-03-22 2019-09-26 장용민 신규한 구조를 갖는 화합물, 이를 포함하는 항염증제 및 시클로옥시게나아제-2 억제제
KR102232979B1 (ko) 2018-03-22 2021-03-29 경북대학교 산학협력단 Do3a 가돌리늄 착물의 신규한 구조를 갖는 화합물, 이를 포함하는 항염증제 및 조영제
WO2019235824A1 (ko) * 2018-06-08 2019-12-12 경북대학교 산학협력단 Cox2 과발현 질환 진단용 조성물 및 이의 스크리닝 방법
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Also Published As

Publication number Publication date
WO2008091530A3 (en) 2009-08-06
EP2114461A2 (en) 2009-11-11
US20100111858A1 (en) 2010-05-06
JP2010516679A (ja) 2010-05-20
WO2008091530A2 (en) 2008-07-31
CN101626787A (zh) 2010-01-13

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