CA2673545A1 - Combination therapy of lower urinary tract disorders with .alpha.2.delta. ligands and nsaids - Google Patents
Combination therapy of lower urinary tract disorders with .alpha.2.delta. ligands and nsaids Download PDFInfo
- Publication number
- CA2673545A1 CA2673545A1 CA002673545A CA2673545A CA2673545A1 CA 2673545 A1 CA2673545 A1 CA 2673545A1 CA 002673545 A CA002673545 A CA 002673545A CA 2673545 A CA2673545 A CA 2673545A CA 2673545 A1 CA2673545 A1 CA 2673545A1
- Authority
- CA
- Canada
- Prior art keywords
- ligand
- nsaid
- aminomethyl
- gabapentin
- combination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
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| US87171906P | 2006-12-22 | 2006-12-22 | |
| US60/871,719 | 2006-12-22 | ||
| PCT/EP2007/011313 WO2008077599A1 (en) | 2006-12-22 | 2007-12-21 | COMBINATION THERAPY OF LOWER URINARY TRACT DISORDERS WITH α2δ LIGANDS AND NSAIDS |
Publications (1)
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|---|---|
| CA2673545A1 true CA2673545A1 (en) | 2008-07-03 |
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| CA002673545A Abandoned CA2673545A1 (en) | 2006-12-22 | 2007-12-21 | Combination therapy of lower urinary tract disorders with .alpha.2.delta. ligands and nsaids |
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| EP (1) | EP2125021B8 (https=) |
| JP (1) | JP5308350B2 (https=) |
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| AU (1) | AU2007338367B2 (https=) |
| BR (1) | BRPI0720351A2 (https=) |
| CA (1) | CA2673545A1 (https=) |
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| DK (1) | DK2125021T3 (https=) |
| EA (1) | EA017171B1 (https=) |
| ES (1) | ES2367881T3 (https=) |
| HR (1) | HRP20110634T1 (https=) |
| IL (1) | IL198891A (https=) |
| MX (1) | MX2009006575A (https=) |
| NO (1) | NO20092581L (https=) |
| NZ (1) | NZ577097A (https=) |
| PL (1) | PL2125021T3 (https=) |
| PT (1) | PT2125021E (https=) |
| RS (1) | RS51940B (https=) |
| SI (1) | SI2125021T1 (https=) |
| UA (1) | UA94979C2 (https=) |
| WO (1) | WO2008077599A1 (https=) |
| ZA (1) | ZA200905038B (https=) |
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| CA2735913A1 (en) | 2008-09-04 | 2010-03-11 | Neurosearch A/S | A method for combating adverse effects arising from antipsychotic treatment |
| US20130323288A1 (en) | 2010-07-08 | 2013-12-05 | Wellesley Pharmaceuticals, Llc | Pharmaceutical formulation for bedwetting and method of use thereof |
| US9415048B2 (en) * | 2010-07-08 | 2016-08-16 | Wellesley Pharmaceuticals, Llc | Pharmaceutical formulation for reducing frequency of urination and method of use thereof |
| CN102648915B (zh) * | 2011-02-28 | 2015-04-15 | 鲁南制药集团股份有限公司 | 一种治疗或预防神经病理性疼痛的药物组合物 |
| ITMI20121263A1 (it) | 2012-07-19 | 2014-01-20 | Recordati Ind Chimica E Farma Ceutica S P A | Forma farmaceutica multistrato |
| US10792326B2 (en) | 2013-06-28 | 2020-10-06 | Wellesley Pharmaceuticals, Llc | Pharmaceutical formulation for bedwetting and method of use thereof |
| CR20160573A (es) * | 2014-06-16 | 2017-03-14 | Farmacéuticos Rayere S A | Composición farmaceutica que combina un anticonvulsivante y un derivado del ácido nicotínico |
Family Cites Families (125)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US4018830A (en) | 1969-09-22 | 1977-04-19 | Merck & Co., Inc. | Phenylthioaralkylamines |
| US3840597A (en) | 1971-02-24 | 1974-10-08 | Riker Laboratories Inc | Substituted 2-phenoxy alkane-sulfonanilides |
| DE2460891C2 (de) | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| GB1561411A (en) | 1977-02-25 | 1980-02-20 | Science Union & Cie | 2-phenoxyphenyl pyrrolidines and pharmaceutical compositions containing them |
| DE2756113A1 (de) | 1977-12-16 | 1979-06-21 | Thomae Gmbh Dr K | Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
| US4885367A (en) | 1987-11-19 | 1989-12-05 | Taisho Pharmaceutical Co., Ltd. | Sulfonanilide compounds |
| US6197819B1 (en) | 1990-11-27 | 2001-03-06 | Northwestern University | Gamma amino butyric acid analogs and optical isomers |
| ZA923283B (en) * | 1991-05-29 | 1993-01-27 | Akzo Nv | Phenoxyphenyl derivatives |
| JP3856816B2 (ja) | 1992-05-20 | 2006-12-13 | ノースウェスターン ユニヴァーシティ | 抗発作治療用のｇａｂａ及びｌ−グルタミン酸類縁体 |
| ATE135697T1 (de) | 1992-10-28 | 1996-04-15 | Shionogi & Co | Benzylidenderivate |
| EP0764644A1 (en) | 1993-01-15 | 1997-03-26 | G.D. Searle & Co. | Use of medicaments containing 3,4-diaryl furans and analogs thereof for treating a gastrointestinal condition |
| CA2113787A1 (en) * | 1993-01-29 | 1994-07-30 | Nobuyuki Hamanaka | Carbocyclic sulfonamides |
| US5380738A (en) | 1993-05-21 | 1995-01-10 | Monsanto Company | 2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents |
| US5474995A (en) | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
| US5344991A (en) * | 1993-10-29 | 1994-09-06 | G.D. Searle & Co. | 1,2 diarylcyclopentenyl compounds for the treatment of inflammation |
| US5466823A (en) | 1993-11-30 | 1995-11-14 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides |
| ES2141916T3 (es) | 1993-11-30 | 2000-04-01 | Searle & Co | Pirazolil-bencenosulfonamidas sustituidas para el tratamiento de la inflamacion. |
| US5475018A (en) | 1993-11-30 | 1995-12-12 | G. D. Searle & Co. | 1,5-diphenyl pyrazole compounds for treatment of inflammation |
| US5418254A (en) | 1994-05-04 | 1995-05-23 | G. D. Searle & Co. | Substituted cyclopentadienyl compounds for the treatment of inflammation |
| WO1995030652A1 (en) | 1994-05-04 | 1995-11-16 | G.D. Searle & Co. | Substituted spirodienes for the treatment of inflammation |
| US5486534A (en) | 1994-07-21 | 1996-01-23 | G. D. Searle & Co. | 3,4-substituted pyrazoles for the treatment of inflammation |
| EP0772606A1 (en) | 1994-07-27 | 1997-05-14 | G.D. SEARLE & CO. | Substituted thiazoles for the treatment of inflammation |
| US5616601A (en) | 1994-07-28 | 1997-04-01 | Gd Searle & Co | 1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation |
| US5620999A (en) | 1994-07-28 | 1997-04-15 | Weier; Richard M. | Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation |
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-
2007
- 2007-12-21 CA CA002673545A patent/CA2673545A1/en not_active Abandoned
- 2007-12-21 AU AU2007338367A patent/AU2007338367B2/en not_active Ceased
- 2007-12-21 KR KR1020097013512A patent/KR20090092307A/ko not_active Ceased
- 2007-12-21 UA UAA200907212A patent/UA94979C2/ru unknown
- 2007-12-21 BR BRPI0720351-9A patent/BRPI0720351A2/pt not_active IP Right Cessation
- 2007-12-21 DK DK07857036.3T patent/DK2125021T3/da active
- 2007-12-21 AT AT07857036T patent/ATE511860T1/de active
- 2007-12-21 CN CN2010105071804A patent/CN102058885B/zh not_active Expired - Fee Related
- 2007-12-21 HR HR20110634T patent/HRP20110634T1/hr unknown
- 2007-12-21 US US11/962,552 patent/US20080153888A1/en not_active Abandoned
- 2007-12-21 CN CNA2007800475013A patent/CN101600458A/zh active Pending
- 2007-12-21 ES ES07857036T patent/ES2367881T3/es active Active
- 2007-12-21 RS RS20110391A patent/RS51940B/sr unknown
- 2007-12-21 SI SI200730624T patent/SI2125021T1/sl unknown
- 2007-12-21 PT PT07857036T patent/PT2125021E/pt unknown
- 2007-12-21 EP EP07857036A patent/EP2125021B8/en active Active
- 2007-12-21 JP JP2009541901A patent/JP5308350B2/ja not_active Expired - Fee Related
- 2007-12-21 NZ NZ577097A patent/NZ577097A/en not_active IP Right Cessation
- 2007-12-21 PL PL07857036T patent/PL2125021T3/pl unknown
- 2007-12-21 EA EA200900868A patent/EA017171B1/ru not_active IP Right Cessation
- 2007-12-21 WO PCT/EP2007/011313 patent/WO2008077599A1/en not_active Ceased
- 2007-12-21 MX MX2009006575A patent/MX2009006575A/es active IP Right Grant
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2009
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- 2009-07-08 NO NO20092581A patent/NO20092581L/no not_active Application Discontinuation
- 2009-07-20 ZA ZA200905038A patent/ZA200905038B/xx unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| EA017171B1 (ru) | 2012-10-30 |
| BRPI0720351A2 (pt) | 2019-05-14 |
| EP2125021A1 (en) | 2009-12-02 |
| SI2125021T1 (sl) | 2011-09-30 |
| PT2125021E (pt) | 2011-07-26 |
| IL198891A (en) | 2013-04-30 |
| ES2367881T3 (es) | 2011-11-10 |
| PL2125021T3 (pl) | 2011-10-31 |
| EP2125021B8 (en) | 2012-02-15 |
| AU2007338367A1 (en) | 2008-07-03 |
| RS51940B (sr) | 2012-02-29 |
| KR20090092307A (ko) | 2009-08-31 |
| IL198891A0 (en) | 2010-02-17 |
| EP2125021B1 (en) | 2011-06-08 |
| JP5308350B2 (ja) | 2013-10-09 |
| CN101600458A (zh) | 2009-12-09 |
| UA94979C2 (uk) | 2011-06-25 |
| HK1155663A1 (en) | 2012-05-25 |
| MX2009006575A (es) | 2009-07-02 |
| ZA200905038B (en) | 2010-04-28 |
| NZ577097A (en) | 2012-05-25 |
| NO20092581L (no) | 2009-07-08 |
| EA200900868A1 (ru) | 2009-12-30 |
| CY1111783T1 (el) | 2015-10-07 |
| JP2010522139A (ja) | 2010-07-01 |
| DK2125021T3 (da) | 2011-09-19 |
| CN102058885A (zh) | 2011-05-18 |
| ATE511860T1 (de) | 2011-06-15 |
| WO2008077599A1 (en) | 2008-07-03 |
| HRP20110634T1 (hr) | 2011-10-31 |
| AU2007338367B2 (en) | 2010-05-20 |
| US20080153888A1 (en) | 2008-06-26 |
| CN102058885B (zh) | 2013-04-10 |
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