ATE135697T1 - Benzylidenderivate - Google Patents

Benzylidenderivate

Info

Publication number
ATE135697T1
ATE135697T1 AT93308369T AT93308369T ATE135697T1 AT E135697 T1 ATE135697 T1 AT E135697T1 AT 93308369 T AT93308369 T AT 93308369T AT 93308369 T AT93308369 T AT 93308369T AT E135697 T1 ATE135697 T1 AT E135697T1
Authority
AT
Austria
Prior art keywords
hydrogen
derivatives
substituted
benzylide
lower alkyl
Prior art date
Application number
AT93308369T
Other languages
English (en)
Inventor
Saichi Matsumoto
Tatsuo Tsuri
Masanao Inagaki
Hirokuni Jyoyama
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Application granted granted Critical
Publication of ATE135697T1 publication Critical patent/ATE135697T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D275/00Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D291/00Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
    • C07D291/02Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms not condensed with other rings
    • C07D291/06Six-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/46Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
    • C07D333/48Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Medicinal Preparation (AREA)
AT93308369T 1992-10-28 1993-10-20 Benzylidenderivate ATE135697T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP28997292 1992-10-28

Publications (1)

Publication Number Publication Date
ATE135697T1 true ATE135697T1 (de) 1996-04-15

Family

ID=17750115

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93308369T ATE135697T1 (de) 1992-10-28 1993-10-20 Benzylidenderivate

Country Status (14)

Country Link
US (1) US5418230A (de)
EP (1) EP0595546B1 (de)
KR (1) KR100281490B1 (de)
CN (1) CN1035614C (de)
AT (1) ATE135697T1 (de)
AU (1) AU675078B2 (de)
CA (1) CA2109498A1 (de)
DE (1) DE69301894T2 (de)
DK (1) DK0595546T3 (de)
ES (1) ES2089736T3 (de)
GR (1) GR3019395T3 (de)
HU (1) HU215924B (de)
NO (1) NO303828B1 (de)
TW (1) TW378207B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3507124B2 (ja) * 1993-05-26 2004-03-15 塩野義製薬株式会社 ベンジリデン誘導体の製造法
DE19700061A1 (de) * 1997-01-03 1998-07-09 Hoechst Schering Agrevo Gmbh Verfahren zur Herstellung von cyclischen N-Aminosulfonamiden
KR20010031319A (ko) 1997-10-24 2001-04-16 요시히코 시오노 항류마티스제
US6649645B1 (en) 1998-12-23 2003-11-18 Pharmacia Corporation Combination therapy of radiation and a COX-2 inhibitor for treatment of neoplasia
WO2000042997A1 (en) * 1999-01-21 2000-07-27 Shionogi & Co., Ltd. Medicinal compositions retarded in the discoloration of phenolic hydroxyl compounds
HUP0302068A3 (en) 2000-07-20 2005-05-30 Lauras As Use of cox-2 inhibitors for treating or preventing immunodeficiency and pharmaceutical compositions containing them
WO2002080974A1 (en) * 2001-04-04 2002-10-17 Sankyo Company, Limited Novel medicinal use of cytokine production inhibitor
AR038957A1 (es) 2001-08-15 2005-02-02 Pharmacia Corp Terapia de combinacion para el tratamiento del cancer
WO2004054560A1 (en) 2002-12-13 2004-07-01 Warner-Lambert Company Llc Alpha-2-delta ligand to treat lower urinary tract symptoms
BRPI0506994A (pt) 2004-01-22 2007-07-03 Pfizer derivados de triazol que inibem a atividade antagonista da vasopressina
BRPI0708804B8 (pt) 2006-03-17 2021-05-25 Cardioxyl Pharmaceuticals Inc compostos derivados de n-hidroxilsulfonamida como doadores de nitroxil, composição farmacêutica e kit
CA2673545A1 (en) 2006-12-22 2008-07-03 Recordati Ireland Limited Combination therapy of lower urinary tract disorders with .alpha.2.delta. ligands and nsaids
GB0903493D0 (en) 2009-02-27 2009-04-08 Vantia Ltd New compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH066571B2 (ja) * 1985-05-09 1994-01-26 エーザイ株式会社 2−ピロリドン誘導体
IL79648A (en) * 1985-08-09 1991-12-12 Lilly Co Eli Pharmaceutical anti-inflammatory and ischemia preventing compositions containing di-t-butylphenol derivatives,some such novel compounds and process for their preparation
ES2056983T3 (es) * 1988-03-21 1994-10-16 Boehringer Ingelheim Pharma Compuestos para inhibir la biosintesis de metabolitos de acido araquidonico derivados de lipoxigenasa.
NZ231534A (en) * 1988-11-29 1992-02-25 Warner Lambert Co 3,5-di-t-butyl-4-hydroxyphenyl-triazoles, oxadiazoles and thiadiazoles; anti-inflammatory compositions
US4895862A (en) * 1989-04-21 1990-01-23 American Home Products Corp. Novel benzyl-3H-1,2,3,5-oxathiadiazole 2-oxides useful as antihyperglycemic agents
IL108962A (en) * 1989-12-21 1996-12-05 Lilly Co Eli Use of hydroxybenzyl substituted sulfur containing heterocyclic derivatives a process for their preparation and pharmaceutical compositions containing them
ATE157355T1 (de) * 1991-01-21 1997-09-15 Shionogi & Co 3-benzyliden-1-carbamoyl-2-pyrrolidon-analoga

Also Published As

Publication number Publication date
AU675078B2 (en) 1997-01-23
HU215924B (hu) 1999-03-29
NO303828B1 (no) 1998-09-07
DK0595546T3 (da) 1996-04-15
NO933870D0 (no) 1993-10-27
ES2089736T3 (es) 1996-10-01
DE69301894D1 (de) 1996-04-25
KR940009163A (ko) 1994-05-20
EP0595546B1 (de) 1996-03-20
HUT70530A (en) 1995-10-30
CN1092414A (zh) 1994-09-21
DE69301894T2 (de) 1996-11-07
GR3019395T3 (en) 1996-06-30
AU4910793A (en) 1994-05-12
NO933870L (no) 1994-04-29
HU9303053D0 (en) 1994-01-28
CN1035614C (zh) 1997-08-13
EP0595546A1 (de) 1994-05-04
KR100281490B1 (ko) 2001-02-15
TW378207B (en) 2000-01-01
US5418230A (en) 1995-05-23
CA2109498A1 (en) 1994-04-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee