PT2125021E - Terapia de combinação de distúrbios do tracto urinário inferior com 2 ligandos e nsaid - Google Patents

Terapia de combinação de distúrbios do tracto urinário inferior com 2 ligandos e nsaid Download PDF

Info

Publication number
PT2125021E
PT2125021E PT07857036T PT07857036T PT2125021E PT 2125021 E PT2125021 E PT 2125021E PT 07857036 T PT07857036 T PT 07857036T PT 07857036 T PT07857036 T PT 07857036T PT 2125021 E PT2125021 E PT 2125021E
Authority
PT
Portugal
Prior art keywords
ligand
nsaid
combination
urinary tract
lower urinary
Prior art date
Application number
PT07857036T
Other languages
English (en)
Inventor
Luciano Guarneri
Amedeo Leonardi
Patrizia Angelico
Original Assignee
Recordati Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Ireland Ltd filed Critical Recordati Ireland Ltd
Publication of PT2125021E publication Critical patent/PT2125021E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
PT07857036T 2006-12-22 2007-12-21 Terapia de combinação de distúrbios do tracto urinário inferior com 2 ligandos e nsaid PT2125021E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87171906P 2006-12-22 2006-12-22

Publications (1)

Publication Number Publication Date
PT2125021E true PT2125021E (pt) 2011-07-26

Family

ID=39272500

Family Applications (1)

Application Number Title Priority Date Filing Date
PT07857036T PT2125021E (pt) 2006-12-22 2007-12-21 Terapia de combinação de distúrbios do tracto urinário inferior com 2 ligandos e nsaid

Country Status (26)

Country Link
US (1) US20080153888A1 (pt)
EP (1) EP2125021B8 (pt)
JP (1) JP5308350B2 (pt)
KR (1) KR20090092307A (pt)
CN (2) CN102058885B (pt)
AT (1) ATE511860T1 (pt)
AU (1) AU2007338367B2 (pt)
BR (1) BRPI0720351A2 (pt)
CA (1) CA2673545A1 (pt)
CY (1) CY1111783T1 (pt)
DK (1) DK2125021T3 (pt)
EA (1) EA017171B1 (pt)
ES (1) ES2367881T3 (pt)
HK (1) HK1155663A1 (pt)
HR (1) HRP20110634T1 (pt)
IL (1) IL198891A (pt)
MX (1) MX2009006575A (pt)
NO (1) NO20092581L (pt)
NZ (1) NZ577097A (pt)
PL (1) PL2125021T3 (pt)
PT (1) PT2125021E (pt)
RS (1) RS51940B (pt)
SI (1) SI2125021T1 (pt)
UA (1) UA94979C2 (pt)
WO (1) WO2008077599A1 (pt)
ZA (1) ZA200905038B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2337564A1 (en) * 2008-09-04 2011-06-29 NeuroSearch A/S A method for combating adverse effects arising from antipsychotic treatment
US20130323288A1 (en) 2010-07-08 2013-12-05 Wellesley Pharmaceuticals, Llc Pharmaceutical formulation for bedwetting and method of use thereof
US9415048B2 (en) * 2010-07-08 2016-08-16 Wellesley Pharmaceuticals, Llc Pharmaceutical formulation for reducing frequency of urination and method of use thereof
CN102648915B (zh) * 2011-02-28 2015-04-15 鲁南制药集团股份有限公司 一种治疗或预防神经病理性疼痛的药物组合物
ITMI20121263A1 (it) 2012-07-19 2014-01-20 Recordati Ind Chimica E Farma Ceutica S P A Forma farmaceutica multistrato
US10792326B2 (en) 2013-06-28 2020-10-06 Wellesley Pharmaceuticals, Llc Pharmaceutical formulation for bedwetting and method of use thereof
CA2951987C (en) 2014-06-16 2017-10-24 Farmaceuticos Rayere, S.A. Pharmaceutical composition that combines an anticonvulsant and a nicotinic acid derivative

Family Cites Families (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4018830A (en) 1969-09-22 1977-04-19 Merck & Co., Inc. Phenylthioaralkylamines
US3840597A (en) 1971-02-24 1974-10-08 Riker Laboratories Inc Substituted 2-phenoxy alkane-sulfonanilides
DE2460891C2 (de) 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
GB1561411A (en) 1977-02-25 1980-02-20 Science Union & Cie 2-phenoxyphenyl pyrrolidines and pharmaceutical compositions containing them
DE2756113A1 (de) 1977-12-16 1979-06-21 Thomae Gmbh Dr K Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4885367A (en) 1987-11-19 1989-12-05 Taisho Pharmaceutical Co., Ltd. Sulfonanilide compounds
US6197819B1 (en) 1990-11-27 2001-03-06 Northwestern University Gamma amino butyric acid analogs and optical isomers
ZA923283B (en) * 1991-05-29 1993-01-27 Akzo Nv Phenoxyphenyl derivatives
DE69330949T2 (de) 1992-05-20 2002-04-04 Univ Northwestern Gaba und l-glutaminsaüre analoga zur behandlung der epilepsie
DK0595546T3 (da) 1992-10-28 1996-04-15 Shionogi & Co Benzylidenderivater
JP3137648B2 (ja) 1993-01-15 2001-02-26 ジー.ディー.サール アンド カンパニー 抗炎症剤としての用途を有する3,4−ジアリールチオフェンおよびその類似体
CA2113787A1 (en) 1993-01-29 1994-07-30 Nobuyuki Hamanaka Carbocyclic sulfonamides
US5380738A (en) 1993-05-21 1995-01-10 Monsanto Company 2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
US5474995A (en) 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
US5344991A (en) 1993-10-29 1994-09-06 G.D. Searle & Co. 1,2 diarylcyclopentenyl compounds for the treatment of inflammation
ES2180233T3 (es) 1993-11-30 2003-02-01 Searle & Co Pirazolil bencenosulfonamidas sustituidas para uso en el tratamiento de la inflamacion.
US5475018A (en) 1993-11-30 1995-12-12 G. D. Searle & Co. 1,5-diphenyl pyrazole compounds for treatment of inflammation
US5466823A (en) 1993-11-30 1995-11-14 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides
US5418254A (en) 1994-05-04 1995-05-23 G. D. Searle & Co. Substituted cyclopentadienyl compounds for the treatment of inflammation
AU2424895A (en) 1994-05-04 1995-11-29 G.D. Searle & Co. Substituted spirodienes for the treatment of inflammation
US5486534A (en) 1994-07-21 1996-01-23 G. D. Searle & Co. 3,4-substituted pyrazoles for the treatment of inflammation
CA2195847A1 (en) 1994-07-27 1996-02-08 John J. Talley Substituted thiazoles for the treatment of inflammation
US5620999A (en) 1994-07-28 1997-04-15 Weier; Richard M. Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation
US5616601A (en) 1994-07-28 1997-04-01 Gd Searle & Co 1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation
US5521213A (en) 1994-08-29 1996-05-28 Merck Frosst Canada, Inc. Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2
US5547975A (en) 1994-09-20 1996-08-20 Talley; John J. Benzopyranopyrazolyl derivatives for the treatment of inflammation
US5739166A (en) 1994-11-29 1998-04-14 G.D. Searle & Co. Substituted terphenyl compounds for the treatment of inflammation
JP3181190B2 (ja) 1994-12-20 2001-07-03 日本たばこ産業株式会社 オキサゾール誘導体
JP2636819B2 (ja) 1994-12-20 1997-07-30 日本たばこ産業株式会社 オキサゾール系複素環式芳香族化合物
US5596008A (en) 1995-02-10 1997-01-21 G. D. Searle & Co. 3,4-Diaryl substituted pyridines for the treatment of inflammation
DE10399017I2 (de) 1995-02-13 2006-04-27 Searle & Co Substituierte isoxazole zur behandlung von Entzündung
US5633272A (en) 1995-02-13 1997-05-27 Talley; John J. Substituted isoxazoles for the treatment of inflammation
US5731343A (en) 1995-02-24 1998-03-24 The Scripps Research Institute Method of use of radicicol for treatment of immunopathological disorders
WO1996037479A1 (en) 1995-05-26 1996-11-28 F. Hoffmann La Roche Ag Cyclohexanone oxime derivatives
WO1996038418A1 (en) 1995-06-02 1996-12-05 G.D. Searle & Co. Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
US5643933A (en) 1995-06-02 1997-07-01 G. D. Searle & Co. Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors
US5968974A (en) 1995-07-19 1999-10-19 Merck & Co., Inc. Method of treating colonic adenomas
DE69633566T2 (de) 1995-07-21 2005-12-08 Savvipharm Inc. Orotatsalze von 5-amino- oder substituierten amino-1,2,3-triazolen zur behandlung von neoplasmen
ES2150679T3 (es) 1995-07-21 2000-12-01 Nycomed Austria Gmbh Derivados de bencenosulfonamidas como inhibidores de la enzima ciclooxigenasa ii.
GB9520584D0 (en) 1995-10-09 1995-12-13 Fujisawa Pharmaceutical Co Pyrazole derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
US5981576A (en) 1995-10-13 1999-11-09 Merck Frosst Canada, Inc. (Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
US6020343A (en) 1995-10-13 2000-02-01 Merck Frosst Canada, Inc. (Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
US6057319A (en) 1995-10-30 2000-05-02 Merck Frosst Canada & Co. 3,4-Diaryl-2-hydroxy-2,5-dihydrofurans as prodrugs to cox-2 inhibitors
CZ293595A3 (cs) 1995-11-09 1999-12-15 Farmak A. S. Deriváty N,N-dimethyl-2-(arylthio)benzylaminu, jejich soli, způsoby jejich přípravy a jejich použití v léčivých přípravcích
US6222048B1 (en) * 1995-12-18 2001-04-24 Merck Frosst Canada & Co. Diaryl-2-(5H)-furanones as Cox-2 inhibitors
DE69712877T2 (de) 1996-02-07 2002-11-14 Warner-Lambert Co., Morris Plains Zyklischaminosäure als pharmazeutische mittel
US5990114A (en) 1996-02-28 1999-11-23 Recordati, S.A., Chemical And Pharmaceutical Company Use of 5-HT1A receptor antagonists for the treatment of urinary incontinence
EA002765B1 (ru) 1996-03-14 2002-08-29 Варнер-Ламберт Компани Производные циклической аминокислоты, фармацевтическая композиция на их основе и способ лечения эпилепсии, приступов слабости, гипокинезии, черепных нарушений, нейродегенеративных или невропатологических нарушений, депрессий, состояний тревоги и паники и боли
PL185990B1 (pl) 1996-03-14 2003-09-30 Warner Lambert Co Nowe mostkowe aminokwasy cykliczne i kompozycje farmaceutyczne zawierające mostkowe aminokwasy cykliczne
US6180651B1 (en) 1996-04-04 2001-01-30 Bristol-Myers Squibb Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics
US5908858A (en) 1996-04-05 1999-06-01 Sankyo Company, Limited 1,2-diphenylpyrrole derivatives, their preparation and their therapeutic uses
BR9708574A (pt) 1996-04-12 1999-08-03 Searle & Co Derivados benzeno sulfonamida substituídos como pródrogas de inibidores cox-2
US5883267A (en) 1996-05-31 1999-03-16 Merck & Co., Inc. Process for making phenyl heterocycles useful as cox-2 inhibitors
US5861419A (en) 1996-07-18 1999-01-19 Merck Frosst Canad, Inc. Substituted pyridines as selective cyclooxygenase-2 inhibitors
IL127441A (en) 1996-07-18 2003-02-12 Merck Frosst Canada Inc Substituted pyridines, pharmaceutical compositions comprising them and their use in the preparation of anti-inflammatory medicaments or as selective cyclooxygenase-2 inhibitors
CA2263663C (en) 1996-10-23 2006-05-30 Justin Stephen Bryans Substituted gamma aminobutyric acids as pharmaceutical agents
ATA16597A (de) 1997-02-03 1998-04-15 Nycomed Austria Gmbh Neue substituierte p-sulfonylaminobenzol- sulfonsäureamide
JP4357004B2 (ja) 1997-04-11 2009-11-04 あすか製薬株式会社 ピラゾール誘導体およびそれを含有するcox阻害剤
US6130334A (en) 1998-04-15 2000-10-10 Merck & Co., Inc. Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors
US6127545A (en) 1997-04-18 2000-10-03 Merck & Co., Inc. Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors
US6034256A (en) 1997-04-21 2000-03-07 G.D. Searle & Co. Substituted benzopyran derivatives for the treatment of inflammation
US6077850A (en) 1997-04-21 2000-06-20 G.D. Searle & Co. Substituted benzopyran analogs for the treatment of inflammation
CA2295021A1 (en) 1997-06-30 1999-01-28 Ortho-Mcneil Pharmaceutical, Inc. 2-substituted imidazoles useful in the treatment of inflammatory diseases
AP9801302A0 (en) 1997-07-23 2000-01-23 Pfizer Indole compounds as anti-inflammatory/analgesic agents..
US6307047B1 (en) 1997-08-22 2001-10-23 Abbott Laboratories Prostaglandin endoperoxide H synthase biosynthesis inhibitors
IL134165A0 (en) * 1997-09-08 2001-04-30 Warner Lambert Co Analgesic compositions comprising anti-epileptic compounds and methods of using same
US5925769A (en) 1997-09-09 1999-07-20 Ortho Pharmaceutical, Corp. Acetylenic 1,5-diarylpyrazoles as antiinflammatory agents
US6046217A (en) 1997-09-12 2000-04-04 Merck Frosst Canada & Co. 2,3,5-trisubstituted pyridines as inhibitors of cyclooxygenase-2
US6140515A (en) 1997-09-24 2000-10-31 Merck & Co., Inc. Process of making 3-aryloxy, 4-aryl furan-2-ones useful as inhibitors of COX-2
US6040450A (en) 1997-09-25 2000-03-21 Merck & Co., Inc. Process for making diaryl pyridines useful as cox-2-inhibitors
JP3756761B2 (ja) 1997-10-27 2006-03-15 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 医薬として有用な環状アミノ酸およびその誘導体
US6080876A (en) 1997-10-29 2000-06-27 Merck & Co., Inc. Process for making phenyl heterocycles useful as COX-2 inhibitors
US6133292A (en) 1997-10-30 2000-10-17 Merck Frosst Canada & Co. Diaryl-5-alkyl-5-methyl-2-(5H)-furanones as selective cyclooxygenase-2-inhibitors
EP1047678B1 (en) 1997-12-16 2004-09-08 Warner-Lambert Company LLC 1-substituted-1-aminomethyl-cycloalkane derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders
PL348305A1 (en) 1997-12-16 2002-05-20 Warner Lambert Co Novel amines as pharmaceutical agents
IL135315A0 (en) 1997-12-16 2001-05-20 Warner Lambert Co 4(3)-substituted-4(3)-aminomethyl-(thio)pyran or -piperidine derivatives (gabapentin analogues), their preparation and their use in the treatment of neurological disorders
JP3256513B2 (ja) 1998-02-11 2002-02-12 ファイザー製薬株式会社 ベンゾイミダゾールシクロオキシゲナーゼ−2阻害剤
US5994379A (en) 1998-02-13 1999-11-30 Merck Frosst Canada, Inc. Bisaryl COX-2 inhibiting compounds, compositions and methods of use
EP1085845A2 (en) 1998-06-08 2001-03-28 Advanced Medicine, Inc. Multibinding inhibitors of cyclooxygenase-2
KR100295206B1 (ko) 1998-08-22 2001-07-12 서경배 디아릴벤조피란유도체및이를함유하는시클로옥시게네이즈-2저해제조성물
CA2347982A1 (en) 1998-10-27 2000-05-04 Abbott Laboratories Prostaglandin endoperoxide h synthase biosynthesis inhibitors
US6077869A (en) 1998-10-29 2000-06-20 Ortho-Mcneil Pharmaceutical, Inc. Aryl phenylhydrazides as selective COX-2 inhibitors for treatment of inflammation
US6441156B1 (en) 1998-12-30 2002-08-27 The United States Of America As Represented By The Department Of Health And Human Services Calcium channel compositions and methods of use thereof
YU56301A (sh) 1999-02-23 2004-05-12 Pfizer Products Inc. Inhibitori resorpcije monoamina za tretiranje poremećaja cns
AU3216600A (en) * 1999-03-10 2000-09-28 Warner-Lambert Company Analgesic compositions comprising anti-epileptic compounds and methods of using same
US6992109B1 (en) * 1999-04-08 2006-01-31 Segal Catherine A Method for the treatment of incontinence
IL145763A0 (en) * 1999-04-08 2002-07-25 Warner Lambert Co Method for the treatment of incontinence
IL146969A0 (en) 1999-06-10 2002-08-14 Warner Lambert Co Mono- and disubstituted 3-propyl gamma-aminobutyric acids
KR100796851B1 (ko) 1999-06-16 2008-01-22 템플 유니버시티-오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 사이클록시게나아제-2의 억제제로서 1-(4-설파밀아릴)-3-치환형-5-아릴-2-피라졸린
MXPA00006605A (es) 1999-07-02 2004-12-09 Pfizer Compuestos de carbonil-indol biciclicos como agentes antiinflamatorios/analgesicos.
US6077868A (en) 1999-07-20 2000-06-20 Wisconsin Alumni Research Foundation Selective inhibition of cyclooxygenase-2
US6387909B1 (en) 1999-07-30 2002-05-14 Recordati S.A. Chemical And Pharmaceutical Company Thienopyranecarboxamide derivatives
US6306861B1 (en) * 1999-07-30 2001-10-23 Recordati S.A. Chemical And Pharmaceutical Company Thienopyrancecarboxamide derivatives
US6306890B1 (en) 1999-08-30 2001-10-23 Vanderbilt University Esters derived from indolealkanols and novel amides derived from indolealkylamides that are selective COX-2 inhibitors
IL149105A0 (en) 1999-10-13 2002-11-10 Pfizer Prodcts Inc Biaryl ether derivatives useful as monoamine reuptake inhibitors
US6403594B1 (en) 1999-10-18 2002-06-11 Recordati, S.A. Chemical And Pharmaceutical Company Benzopyran derivatives
US6365591B1 (en) 1999-10-18 2002-04-02 Recordati, S.A., Chemical And Pharmacueticals Company Isoxazolecarboxamide derivatives
US6083969A (en) 1999-10-20 2000-07-04 Ortho-Mcneil Pharaceutical, Inc. 1,3- and 2,3-diarylcycloalkano and cycloalkeno pyrazoles as selective inhibitors of cyclooxygenase-2 and antiinflammatory agents
HN2000000224A (es) 1999-10-20 2001-04-11 Warner Lambert Co Aminoacidos biciclicos como agentes farmaceuticos
GB2362646A (en) 2000-05-26 2001-11-28 Warner Lambert Co Cyclic amino acid derivatives useful as pharmaceutical agents
GB2365425A (en) 2000-08-01 2002-02-20 Parke Davis & Co Ltd Alkyl amino acid derivatives useful as pharmaceutical agents
MXPA03002090A (es) 2000-09-14 2003-06-19 Gruenenthal Gmbh °-tio-aminoacidos.
AR034160A1 (es) 2000-09-30 2004-02-04 Gruenenthal Gmbh Sulfonilguanidinas, medicamentos que contienen estos compuestos y el uso de sulfonilguanidinas
DE10048715A1 (de) 2000-09-30 2004-05-19 Grünenthal GmbH Verwendung von Aminosäure zur Behandlung von Schmerz
AU2002211863A1 (en) 2000-10-06 2002-04-15 Xenoport, Inc. Bile-acid derived compounds for providing sustained systemic concentrations of drugs after oral administration
GB2367869B (en) 2000-10-14 2004-10-06 Trw Ltd Rear-axle demand for use with front push-through in electrohydraulic (EHB) braking systems
US6359182B1 (en) 2000-10-26 2002-03-19 Duke University C-nitroso compounds and use thereof
GB2368579A (en) 2000-10-31 2002-05-08 Parke Davis & Co Ltd Azole pharmaceutical agents
WO2002042414A2 (en) 2000-11-17 2002-05-30 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
ITMI20010733A1 (it) 2001-04-05 2002-10-05 Recordati Chem Pharm Uso di inibitori dell'isoenzina cox-2 per il trattamento dell'incontinenza urinaria
DE60235619D1 (de) 2001-04-19 2010-04-22 Warner Lambert Co Kondensierte bizyklische oder trizyklische aminosäuren
ATE380029T1 (de) 2001-06-11 2007-12-15 Xenoport Inc Prodrugs von gaba-analoga, zusammensetzungen und ihre verwendungszwecke
ITMI20011308A1 (it) 2001-06-21 2002-12-21 Nicox Sa Farmaci per il dolore cronico
WO2003070233A1 (en) * 2002-02-19 2003-08-28 Pharmacia Corporation Use of cyclooxygenase inhibitors and antimuscarinic agents for the treatment of incontinence
US20040132826A1 (en) * 2002-10-25 2004-07-08 Collegium Pharmaceutical, Inc. Modified release compositions of milnacipran
KR20070091049A (ko) 2002-12-13 2007-09-06 워너-램버트 캄파니 엘엘씨 하부요로증상을 치료하기 위한 알파-2-델타 리간드
DE60315258T2 (de) 2002-12-20 2008-05-08 Dynogen Pharmaceuticals Inc., Waltham Behandlung von nicht-schmerzhaften blasenstörungen mit modulatoren der alpha-2-delta-untereinheit des calciumkanals
US6846823B2 (en) * 2003-04-04 2005-01-25 Dynogen Pharmaceuticals, Inc. Method of treating lower urinary tract disorders
US20040248979A1 (en) * 2003-06-03 2004-12-09 Dynogen Pharmaceuticals, Inc. Method of treating lower urinary tract disorders
JP2007505149A (ja) 2003-09-11 2007-03-08 ゼノポート,インコーポレイティド ギャバ類似体のプロドラッグを用いる尿失禁の治療および/あるいは予防
ES2244326B1 (es) * 2004-04-05 2007-02-16 Laboratorios Del Dr. Esteve, S.A. Combinacion de substancias activas.
JP2008528494A (ja) 2005-01-21 2008-07-31 ファーマノバ インコーポレイテッド 医薬製剤および使用方法
WO2006090275A1 (en) * 2005-02-24 2006-08-31 Pfizer Limited Treatment of incontinence
EP1879578A4 (en) * 2005-03-21 2009-05-13 Dov Pharmaceutical Inc METHODS AND COMPOSITIONS FOR THE TREATMENT OF URINARY INCONTINENCE
GB0509993D0 (en) * 2005-05-17 2005-06-22 Bamford Antony S Load sharing riser tensioning system

Also Published As

Publication number Publication date
AU2007338367B2 (en) 2010-05-20
US20080153888A1 (en) 2008-06-26
ZA200905038B (en) 2010-04-28
ATE511860T1 (de) 2011-06-15
PL2125021T3 (pl) 2011-10-31
CN102058885A (zh) 2011-05-18
EA200900868A1 (ru) 2009-12-30
BRPI0720351A2 (pt) 2019-05-14
RS51940B (en) 2012-02-29
EP2125021A1 (en) 2009-12-02
IL198891A0 (en) 2010-02-17
AU2007338367A1 (en) 2008-07-03
NO20092581L (no) 2009-07-08
HRP20110634T1 (hr) 2011-10-31
JP2010522139A (ja) 2010-07-01
JP5308350B2 (ja) 2013-10-09
HK1155663A1 (en) 2012-05-25
DK2125021T3 (da) 2011-09-19
EP2125021B8 (en) 2012-02-15
EP2125021B1 (en) 2011-06-08
SI2125021T1 (sl) 2011-09-30
CY1111783T1 (el) 2015-10-07
UA94979C2 (uk) 2011-06-25
CA2673545A1 (en) 2008-07-03
EA017171B1 (ru) 2012-10-30
KR20090092307A (ko) 2009-08-31
CN102058885B (zh) 2013-04-10
WO2008077599A1 (en) 2008-07-03
NZ577097A (en) 2012-05-25
ES2367881T3 (es) 2011-11-10
IL198891A (en) 2013-04-30
MX2009006575A (es) 2009-07-02
CN101600458A (zh) 2009-12-09

Similar Documents

Publication Publication Date Title
HK1155663A1 (en) Combination therapy of lower urinary tract disorders with
EP2331095A4 (en) CYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND METHOD OF USE THEREOF
EA201490279A1 (ru) Ингибиторы кинуренин-3-монооксигеназы, фармацевтические композиции и способы их применения
WO2005072045A3 (en) The combined use of glp-1 agonists and gastrin for regulating blood glucose levels
WO2002098352A3 (en) PHARMACEUTICAL COMPOSITIONS FOR THE COORDINATED DELIVERY OF NSAIDs
GB0410266D0 (en) Treatment of apoptosis
WO2007103113A3 (en) Dosage forms for administering combinations of drugs
PH12017502049A1 (en) Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
MX2014001088A (es) Ciertos inhibidores de quinurenina-3-monooxigenasa, composiciones farmaceuticas, y metodos de uso de las mismas.
WO2007062093A3 (en) Combination therapy for the treatment of cancer comprising a metalloprotease inhibitor
RU2013145498A (ru) Способы и композиции для лечения гиперурикемии и метаболических нарушений, связанных с гиперурикемией
WO2007112274A3 (en) Formulations of low dose non-steroidal anti-inflammatory drugs and beta-cyclodextrin
Sivrikaya Multimodal analgesia for postoperative pain management
WO2005074536A3 (en) Compositions and methods using proton pump inhibitors
RU2007132725A (ru) Применение неопиатного анальгетика флупиртина для лечения гиперактивности мочевого пузыря и родственных заболеваний, в том числе неотложного недержания мочи, проблем с мочеотделением, как результата гиперплазии предстательной железы и синдрома раздраженного кишечника
CA2632207C (en) Use of calcitonin for the treatment of ra
Krishna et al. Efficacy of a single dose of a transdermal diclofenac patch as pre-emptive postoperative analgesia: a comparison with intramuscular diclofenac
RU2009118962A (ru) Применение антагонистов il-1 для лечения подагры и псевдоподагры
EA200500941A1 (ru) Средство для лечения болезней суставов
JP2011500589A5 (pt)
RU2009116629A (ru) Азитромицин для лечения узелковых угрей
Coppens et al. Adjuvants for balanced anesthesia in ambulatory surgery
WO2006124544A3 (en) Use of tyrosine kinase inhibitors in the treatment of metabolic disorders
JP2019533018A5 (pt)
Stelea et al. UPDATE ON THE USE OF ANALGESICS IN ORAL SURGERY