CA2670526A1 - Indicator immobilization on assay devices - Google Patents

Indicator immobilization on assay devices Download PDF

Info

Publication number
CA2670526A1
CA2670526A1 CA002670526A CA2670526A CA2670526A1 CA 2670526 A1 CA2670526 A1 CA 2670526A1 CA 002670526 A CA002670526 A CA 002670526A CA 2670526 A CA2670526 A CA 2670526A CA 2670526 A1 CA2670526 A1 CA 2670526A1
Authority
CA
Canada
Prior art keywords
lateral flow
assay device
indicator
flow assay
analyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002670526A
Other languages
English (en)
French (fr)
Inventor
Xuedong Song
Curtis Sayre
Shawn R. Feaster
Julie Villanueva
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kimberly Clark Worldwide Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2670526A1 publication Critical patent/CA2670526A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90Plate chromatography, e.g. thin layer or paper chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • G01N33/54387Immunochromatographic test strips
    • G01N33/54388Immunochromatographic test strips based on lateral flow
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/97Test strip or test slide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81Tube, bottle, or dipstick

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002670526A 2006-12-15 2007-09-28 Indicator immobilization on assay devices Abandoned CA2670526A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/640,100 US7935538B2 (en) 2006-12-15 2006-12-15 Indicator immobilization on assay devices
US11/640,100 2006-12-15
PCT/IB2007/053962 WO2008075216A1 (en) 2006-12-15 2007-09-28 Indicator immobilization on assay devices

Publications (1)

Publication Number Publication Date
CA2670526A1 true CA2670526A1 (en) 2008-06-26

Family

ID=39247279

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002670526A Abandoned CA2670526A1 (en) 2006-12-15 2007-09-28 Indicator immobilization on assay devices

Country Status (7)

Country Link
US (1) US7935538B2 (enExample)
EP (1) EP2092332B1 (enExample)
JP (1) JP5296703B2 (enExample)
KR (1) KR101481189B1 (enExample)
CN (1) CN101558301B (enExample)
CA (1) CA2670526A1 (enExample)
WO (1) WO2008075216A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8901366B2 (en) * 2007-12-14 2014-12-02 Kimberly Clark Worldwide, Inc. Urine volume hydration test devices
US9103796B2 (en) * 2007-12-14 2015-08-11 Kimberly-Clark Worldwide, Inc. Multi-layered devices for analyte detection
US20100159611A1 (en) * 2008-12-18 2010-06-24 Xuedong Song Hydration/dehydration sensor
US20130052653A1 (en) * 2009-11-24 2013-02-28 Argos, Inc. Devices for detection of analytes
US9733242B2 (en) 2012-10-07 2017-08-15 Sevident, Inc. Devices for capturing analyte
US9910040B2 (en) 2012-07-09 2018-03-06 Sevident, Inc. Molecular nets comprising capture agents and linking agents
US8920857B2 (en) * 2010-12-22 2014-12-30 Michael T. Abramson System and method for detection of a contaminated beverage
WO2012170206A2 (en) * 2011-06-07 2012-12-13 Diagnostic Innovations, Llc Color-producing diagnostic systems, reagents and methods
JP5903492B2 (ja) * 2011-09-16 2016-04-13 クレド バイオメディカル ピーティーイー リミテッド 分子診断アッセイデバイス及び使用方法
WO2013105572A1 (ja) * 2012-01-11 2013-07-18 株式会社ダイセル クロマトグラフ媒体
GB201321430D0 (en) * 2013-12-04 2014-01-15 Spd Swiss Prec Diagnostics Gmbh Assay device
KR101593114B1 (ko) * 2014-04-09 2016-02-11 이성동 바이오센서
US9591290B2 (en) 2014-06-10 2017-03-07 Bitanimate, Inc. Stereoscopic video generation
FR3034686B1 (fr) * 2015-04-13 2019-06-14 Commissariat A L'energie Atomique Et Aux Energies Alternatives Procede pour greffer un indicateur colore sur un support solide et kit de mise en œuvre
CN105699370B (zh) * 2016-01-20 2018-09-18 江西华清博恩生物科技有限公司 羊水检测指示剂组合物、其制备和相应的羊水检测护垫
US11104933B1 (en) 2016-03-22 2021-08-31 Cleu Diagnostics, Llc Compositions and methods for determining the presence of active leukocyte cells using an electrochemical assay
WO2017165953A1 (en) * 2016-04-01 2017-10-05 7905122 Canada Inc. Water-absorbing material and uses thereof
GB201614053D0 (en) * 2016-08-17 2016-09-28 Microarray Ltd Determining the condition of a wound
JP6635345B2 (ja) * 2017-02-14 2020-01-22 学校法人慶應義塾 尿中のバイオマーカーを検出するための方法及び該方法に用いるためのキット
JP7005656B2 (ja) 2017-05-04 2022-02-10 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッド 免疫測定法におけるフック効果の干渉を最小化するための装置および方法
CN115210557A (zh) * 2019-10-21 2022-10-18 韦里特克美国有限公司 芬太尼类似物检测方法及其试剂盒
CN112161972B (zh) * 2020-08-14 2021-04-20 大连理工大学 一种快速分级定量检测酸性溶液中芳伯胺含量的检测试纸组及其应用
EP4384826A1 (en) * 2021-08-11 2024-06-19 Senzo Health Limited High sensitivity analyte network detection flow assays and related methods
CN115586142A (zh) * 2021-10-21 2023-01-10 新加坡国立大学 一种三价铁离子传感分子材料及其应用

Family Cites Families (159)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) * 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
US3951748A (en) * 1974-11-11 1976-04-20 Medical Products, Inc. Sensitized matrix for detection of disease
EP0111762B1 (en) 1980-06-20 1987-11-19 Unilever Plc Processes and apparatus for carrying out specific binding assays
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
EP0046742B1 (en) * 1980-08-25 1984-06-27 KabiVitrum AB Peptide substrates for determination of protease activity
US4483920A (en) 1982-05-17 1984-11-20 Hahnemann University Immobilization of message RNA directly from cells onto filter material
JPH0665987B2 (ja) * 1982-11-19 1994-08-24 富士写真フイルム株式会社 分析要素
US4895809A (en) * 1984-01-09 1990-01-23 Varian Associates, Inc. Immobilized antigen-antibody displacement process
GB8406752D0 (en) 1984-03-15 1984-04-18 Unilever Plc Chemical and clinical tests
US4743560A (en) * 1984-03-26 1988-05-10 Becton Dickinson And Company Solid phase assay
DE3413078A1 (de) * 1984-04-06 1985-10-24 Miles Laboratories, Inc., Elkhart, Ind. Chromogene aminosaeure- und peptidester, verfahren zu deren herstellung, verwendung dieser verbindungen in analysenverfahren sowie mittel zum nachweis esterolytischer und/oder proteolytischer enzyme
DE3413077A1 (de) * 1984-04-06 1985-10-17 Miles Laboratories, Inc., Elkhart, Ind. Chromogene aminosaeure- und peptidester, verfahren zu deren herstellung, verwendung dieser verbindungen in analysenverfahren sowie mittel zum nachweis esterolytischer und/oder proteolytischer enzyme
US4657855A (en) * 1984-04-06 1987-04-14 Miles Laboratories, Inc. Composition and test device for determining the presence of leukocytes, esterase and protease in a test sample
US4637979A (en) * 1984-04-06 1987-01-20 Miles Laboratories, Inc. Composition and test device for determining the presence of leukocytes containing a zwitterion coupling agent
GB2161165A (en) * 1984-06-12 1986-01-08 Cambridge Patent Dev Secondary antibodies
US4806311A (en) * 1985-08-28 1989-02-21 Miles Inc. Multizone analytical element having labeled reagent concentration zone
TW203120B (enExample) 1985-10-04 1993-04-01 Abbott Lab
US5500350A (en) * 1985-10-30 1996-03-19 Celltech Limited Binding assay device
GB8528720D0 (en) 1985-11-21 1985-12-24 Williams J Disposable nappies
US5178831A (en) * 1986-10-08 1993-01-12 Dai Nippon Insatsu Kab Ushiki Kaisha Device for testing body fluids
US4835099A (en) * 1986-11-20 1989-05-30 Becton, Dickinson And Company Signal enhancement in immunoassay by modulation of enzymatic catalysis
US4954435A (en) 1987-01-12 1990-09-04 Becton, Dickinson And Company Indirect colorimetric detection of an analyte in a sample using ratio of light signals
USRE38430E1 (en) * 1987-03-27 2004-02-17 Becton, Dickinson And Company Solid phase chromatographic immunoassay
CA1303983C (en) * 1987-03-27 1992-06-23 Robert W. Rosenstein Solid phase assay
JPH0684970B2 (ja) * 1987-03-31 1994-10-26 株式会社京都医科学研究所 糞便中の潜血検出方法
ES2150428T3 (es) * 1987-04-27 2000-12-01 Unilever Nv Ensayos de union especifica.
US4904583A (en) * 1987-05-26 1990-02-27 Becton, Dickinson And Company Cascade immunoassay by multiple binding reactions
US4943522A (en) * 1987-06-01 1990-07-24 Quidel Lateral flow, non-bibulous membrane assay protocols
US5120643A (en) * 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
US4956302A (en) 1987-09-11 1990-09-11 Abbott Laboratories Lateral flow chromatographic binding assay device
US5571667A (en) 1987-10-01 1996-11-05 Chu; Albert E. Elongated membrane flow-through diagnostic device and method
US5073340A (en) 1987-10-08 1991-12-17 Becton, Dickinson And Company Depositing a binder on a solid support
US4978625A (en) 1987-10-19 1990-12-18 Becton, Dickinson And Company Fluorescence immunoassay using water insoluble dyes
US5275785A (en) * 1987-10-30 1994-01-04 Unilever Patent Holdings B.V. Test device for detecting an analyte in a liquid sample
US5670381A (en) 1988-01-29 1997-09-23 Abbott Laboratories Devices for performing ion-capture binding assays
JPH01206257A (ja) * 1988-02-12 1989-08-18 Kokusai Shiyaku Kk ウロビリノーゲン検出用試薬および器具
US5573919A (en) 1988-06-02 1996-11-12 Carter-Wallace Assay using an absorbent material
AU2684488A (en) 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
US5252459A (en) 1988-09-23 1993-10-12 Abbott Laboratories Indicator reagents, diagnostic assays and test kits employing organic polymer latex particles
US5003178A (en) * 1988-11-14 1991-03-26 Electron Vision Corporation Large-area uniform electron source
US5208143A (en) * 1988-11-17 1993-05-04 Becton, Dickinson And Company Immunoassay on a preblocked solid surface
MY104234A (en) * 1988-11-17 1994-02-28 Becton Dickinson Co Immunoassay on a preblocked solid surface
US6352862B1 (en) * 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
US5185127A (en) * 1989-09-21 1993-02-09 Becton, Dickinson And Company Test device including flow control means
US5075078A (en) 1989-10-05 1991-12-24 Abbott Laboratories Self-performing immunochromatographic device
US5252743A (en) 1989-11-13 1993-10-12 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
US6274324B1 (en) * 1989-12-01 2001-08-14 Unilever Patent Holdings B.V. Specific binding reagent comprising a variable domain protein linked to a support or tracer
US5252496A (en) 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
US5238652A (en) * 1990-06-20 1993-08-24 Drug Screening Systems, Inc. Analytical test devices for competition assay for drugs of non-protein antigens using immunochromatographic techniques
US5686315A (en) 1991-06-14 1997-11-11 Quidel Corporation Assay device for one step detection of analyte
US5428690A (en) * 1991-09-23 1995-06-27 Becton Dickinson And Company Method and apparatus for automated assay of biological specimens
ES2151902T3 (es) * 1992-03-10 2001-01-16 Quidel Corp Medio de separacion de globulos rojos para dosificarlos mediante union especifica.
DE4217474A1 (de) * 1992-05-27 1993-12-02 Boehringer Mannheim Gmbh Verfahren und Mittel zur Bestimmung eines Analyts
US5395754A (en) * 1992-07-31 1995-03-07 Hybritech Incorporated Membrane-based immunoassay method
DE69331061T2 (de) * 1992-08-10 2002-06-06 Monolithic System Tech Inc Fehlertolerantes hierarchisiertes Bussystem
US5354692A (en) 1992-09-08 1994-10-11 Pacific Biotech, Inc. Analyte detection device including a hydrophobic barrier for improved fluid flow
US5807752A (en) 1992-09-11 1998-09-15 Boehringer Mannheim Corporation Assay using an unblocked solid phase with immobilized analyte binding partner
US5571864A (en) * 1993-03-23 1996-11-05 Regents Of The University Of Minnesota Miscible polyolefin blends with modifying polyolefin having matching segment lengths
US5409664A (en) * 1993-09-28 1995-04-25 Chemtrak, Inc. Laminated assay device
US5547833A (en) * 1994-01-04 1996-08-20 Intracel Corporation Radial flow assay, delivering member, test kit, and methods
DE4403437A1 (de) 1994-02-04 1995-08-10 Karl Heinz Stawski Einmalwindel
US5658747A (en) * 1994-05-10 1997-08-19 Biocontrol System, Inc. Compositions and methods for control of reactivity between diagnostic reagents and microorganisms
US5501836A (en) * 1994-07-11 1996-03-26 Hewlett Packard Company Entrapped non-enzymatic macromolecules for chemical sensing
US5464739A (en) 1994-08-22 1995-11-07 Bayer Corporation Composition method for determining the presence of leukocyte cells, esterase or protease in a test sample
GB9419267D0 (en) * 1994-09-23 1994-11-09 Unilever Plc Assay devices
US5571684A (en) 1994-11-07 1996-11-05 Litmus Concepts, Inc. Assay for proline iminopeptidase and other hydrolytic activities
CA2161574A1 (en) 1994-11-15 1996-05-16 James Noffsinger Methodology for colorimetrically determining the concentration of white blood cells in a biological fluid
EP0793806B1 (en) 1994-11-24 2003-04-09 Inverness Medical Switzerland GmbH Recovery of and uses of specific binding agents
US5567596A (en) * 1994-12-29 1996-10-22 Research Foundation Of State University Of New York Rapid assay of activators and inhibitors of clotting
US5569608A (en) 1995-01-30 1996-10-29 Bayer Corporation Quantitative detection of analytes on immunochromatographic strips
GB9505425D0 (en) * 1995-03-17 1995-05-03 Unilever Plc Assay devices
US5712172A (en) * 1995-05-18 1998-01-27 Wyntek Diagnostics, Inc. One step immunochromatographic device and method of use
US5788863A (en) * 1995-12-13 1998-08-04 Becton Dickinson And Company Apparatus and method for conducting an assay using reverse flow through a membrane
US5741662A (en) * 1995-12-18 1998-04-21 Quidel Corporation Direct stain specific binding assays for microorganisms
US5945281A (en) * 1996-02-02 1999-08-31 Becton, Dickinson And Company Method and apparatus for determining an analyte from a sample fluid
WO1997029366A1 (en) * 1996-02-08 1997-08-14 Australian Membrane And Biotechnology Research Institute Enzyme detection biosensors
US5874216A (en) * 1996-02-23 1999-02-23 Ensys Environmental Products, Inc. Indirect label assay device for detecting small molecules and method of use thereof
ATE247830T1 (de) 1996-05-23 2003-09-15 Inverness Medical Switzerland Verbesserungen in oder in bezug auf spezifische bindungsassays
KR980010425A (ko) * 1996-07-30 1998-04-30 안홍원 뇨중 백혈구 및 단백질 분해 효소 검출을 위한 조성물 및 측정기구
US5998221A (en) 1996-09-25 1999-12-07 Becton, Dickinson And Company Non-instrumented assay with quantitative and qualitative results
US6194220B1 (en) * 1996-09-25 2001-02-27 Becton, Dickinson And Company Non-instrumented assay with quantitative and qualitative results
US5798273A (en) * 1996-09-25 1998-08-25 Becton Dickinson And Company Direct read lateral flow assay for small analytes
ES2168444T3 (es) 1996-09-27 2002-06-16 Inverness Medical Switzerland Fabricacion de tiras de prueba.
EP0833157B1 (en) 1996-09-27 2002-11-20 Inverness Medical Switzerland GmbH Assay reagents and devices
DE69626016T2 (de) 1996-09-27 2004-01-08 Inverness Medical Switzerland Gmbh Test-Kit und Vorrichtungen
US6979576B1 (en) 1997-07-25 2005-12-27 Shu-Ching Cheng Methods of use of one step immunochromatographic device for Streptococcus A antigen
US5962995A (en) 1997-01-02 1999-10-05 Applied Advanced Technologies, Inc. Electron beam accelerator
US6407492B1 (en) * 1997-01-02 2002-06-18 Advanced Electron Beams, Inc. Electron beam accelerator
US6057165A (en) * 1997-02-07 2000-05-02 Becton, Dickinson And Company Quality control procedure for membrane flow-through diagnostic assay devices
GB2322192B (en) 1997-02-14 2001-01-31 Unilever Plc Assay devices
US5989924A (en) 1997-09-30 1999-11-23 Becton, Dickinson And Company Device for determining an analyte in a sample
US6077669A (en) * 1997-11-04 2000-06-20 Becton Dickinson And Company Kit and method for fluorescence based detection assay
US6060256A (en) * 1997-12-16 2000-05-09 Kimberly-Clark Worldwide, Inc. Optical diffraction biosensor
US6017723A (en) * 1998-03-27 2000-01-25 Long Island Jewish Medical Center Method for isolating inhibitors of protease activity
GB9807134D0 (en) * 1998-04-02 1998-06-03 Unilever Plc Test methods devices and test kits
ES2143434B1 (es) 1998-09-16 2000-12-16 Cerrato Paula Jimenez Pañal con indicadores sensibles al estado de la orina que lo impregna visualiazables desde el exterior.
US6140136A (en) 1998-09-18 2000-10-31 Syntron Bioresearch, Inc. Analytical test device and method of use
AUPP713498A0 (en) * 1998-11-17 1998-12-10 Chandler, Howard Milne A method of detecting blood
DE19927783A1 (de) * 1999-06-18 2000-12-21 Roche Diagnostics Gmbh Element zur Bestimmung eines Analyts in einer Flüssigkeit, entsprechendes Bestimmungsverfahren unter Verwendung des Elementes sowie Kit zur Bestimmugn eines Analyts
JP2001021560A (ja) * 1999-07-07 2001-01-26 Nitto Denko Corp 免疫クロマト測定法
US6485926B2 (en) 1999-12-22 2002-11-26 Fuji Photo Film Co., Ltd. Method for measuring protease activity
US6515194B2 (en) 1999-12-23 2003-02-04 Ryan R. Neading Diaper having centrally-located chromatographic layer with peripherally-located wetness indicator
DE10009503A1 (de) * 2000-02-29 2001-08-30 Roche Diagnostics Gmbh Verfahren zur Immobilisierung von Konjugaten in diagnostischen Tests
US6607922B2 (en) * 2000-03-17 2003-08-19 Quantum Design, Inc. Immunochromatographic assay method and apparatus
US20080050839A1 (en) * 2000-03-21 2008-02-28 Suslick Kenneth S Apparatus and method for detecting lung cancer using exhaled breath
JP2001349892A (ja) * 2000-04-03 2001-12-21 Unilever Nv 検査方法及びデバイス
CA2342683A1 (en) * 2000-04-03 2001-10-03 Unilever Plc Test methods and devices
US6699722B2 (en) * 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes
US6627459B1 (en) 2000-04-19 2003-09-30 Applied Biotech, Inc. Immunoassay controls
SE0001667D0 (sv) * 2000-05-05 2000-05-05 Pharmacia & Upjohn Diag Ab Assay device with timer function
CU22968A1 (es) * 2000-06-07 2004-07-14 Ct Ingenieria Genetica Biotech Procedimiento para la detección de anticuerpos anti transglutaminasa con utilidad en el diagnóstico de la enfermedad celíaca
JP2004501987A (ja) 2000-06-19 2004-01-22 キンバリー クラーク ワールドワイド インコーポレイテッド 新規な光開始剤及びその用途
US7052831B2 (en) * 2000-09-29 2006-05-30 Becton Dickinson And Company Detection of multiple analytes from a single sample using a multi-well, multi-analyte flow-through diagnostic test device
US6653149B1 (en) 2000-10-16 2003-11-25 Applied Biotech Inc. Specimen collection device and method
JP2002122598A (ja) * 2000-10-16 2002-04-26 Nitto Denko Corp 酵素免疫クロマトグラフ法用試験片および展開組成物
US6524864B2 (en) * 2000-12-28 2003-02-25 Aurora L. Fernandez Decastro Test strip for simultaneous detection of a plurality of analytes
US6767710B2 (en) * 2001-03-30 2004-07-27 Praxsys Biosystems, Llc Prewetting stop flow test strip
US6565808B2 (en) * 2001-05-18 2003-05-20 Acon Laboratories Line test device and methods of use
US6669908B2 (en) 2001-07-25 2003-12-30 Applied Biotech, Inc. Urine test device
AU2002357754A1 (en) 2001-12-24 2003-07-24 Kimberly-Clark Worldwide, Inc. Flow-through assay with an internal calibration system using polyelectrolyte
US20030119203A1 (en) * 2001-12-24 2003-06-26 Kimberly-Clark Worldwide, Inc. Lateral flow assay devices and methods for conducting assays
AU2002360205A1 (en) * 2001-12-27 2003-07-30 Inverness Medical Switzerland Gmbh System and method for fluorescence detection
US7049150B2 (en) * 2001-12-28 2006-05-23 Varian, Inc. Binding assay device with non-absorbent carrier material
WO2004003527A1 (en) * 2002-06-27 2004-01-08 Unipath Limited Assay reader
US6875185B2 (en) * 2002-07-29 2005-04-05 Branan Medical Corporation Integrated confirmation sample in a body fluid test device and method of using
US7314763B2 (en) * 2002-08-27 2008-01-01 Kimberly-Clark Worldwide, Inc. Fluidics-based assay devices
US7285424B2 (en) * 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7432105B2 (en) * 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
US7781172B2 (en) * 2003-11-21 2010-08-24 Kimberly-Clark Worldwide, Inc. Method for extending the dynamic detection range of assay devices
US20040121334A1 (en) * 2002-12-19 2004-06-24 Kimberly-Clark Worldwide, Inc. Self-calibrated flow-through assay devices
US7247500B2 (en) * 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
US6780896B2 (en) * 2002-12-20 2004-08-24 Kimberly-Clark Worldwide, Inc. Stabilized photoinitiators and applications thereof
US7459314B2 (en) * 2003-02-13 2008-12-02 Inverness Medical Switzerland Gmbh Lateral flow immunoassay controls
US7297548B2 (en) * 2003-03-28 2007-11-20 Terumo Kabushiki Kaisha Solid-phase saccharide sensing compounds
WO2004096817A1 (en) * 2003-03-28 2004-11-11 Terumo Corporation Of Japan Solid-phase saccharide sensing compounds
US7851209B2 (en) 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
US20040197819A1 (en) 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US7239394B2 (en) * 2003-06-04 2007-07-03 Inverness Medical Switzerland Gmbh Early determination of assay results
US7315378B2 (en) * 2003-06-04 2008-01-01 Inverness Medical Switzerland Gmbh Optical arrangement for assay reading device
JP2005056604A (ja) * 2003-08-06 2005-03-03 Hitachi Displays Ltd 自発光型平面表示装置
JP4458327B2 (ja) 2003-08-28 2010-04-28 キヤノン株式会社 標的物質の定量方法および該方法に用いるプローブ担体
US20050112635A1 (en) * 2003-09-22 2005-05-26 Becton, Dickinson And Company Quantification of analytes using internal standards
US7943395B2 (en) * 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US20050131287A1 (en) * 2003-12-16 2005-06-16 Kimberly-Clark Worldwide, Inc. Detection of premature rupture of the amniotic membrane
US20050191704A1 (en) 2004-03-01 2005-09-01 Kimberly-Clark Worldwide, Inc. Assay devices utilizing chemichromic dyes
US20050227370A1 (en) 2004-03-08 2005-10-13 Ramel Urs A Body fluid analyte meter & cartridge system for performing combined general chemical and specific binding assays
US7524673B2 (en) * 2004-05-10 2009-04-28 3M Innovative Properties Company Biological soil detector
US20060029976A1 (en) * 2004-08-06 2006-02-09 Mcvicker Jerry K Method for the detection of C-reactive protein in mammalian fluids
US7662562B2 (en) * 2004-08-10 2010-02-16 Becton, Dickinson And Company Method for rapid identification of microorganisms
JP2006119119A (ja) * 2004-09-24 2006-05-11 Fuji Xerox Co Ltd ポリマー及びリガンド固定化用担体
US7629127B2 (en) * 2005-01-21 2009-12-08 Dexall Biomedical Labs, Inc. Method for the visual detection of specific antibodies by the use of lateral flow assays
WO2006104962A1 (en) * 2005-03-28 2006-10-05 Becton, Dickinson And Company An improved system and method for stirring suspended solids in liquid media
US7939342B2 (en) 2005-03-30 2011-05-10 Kimberly-Clark Worldwide, Inc. Diagnostic test kits employing an internal calibration system
US20060240569A1 (en) 2005-04-20 2006-10-26 Becton, Dickinson And Company Semi-quantitative immunochromatographic device
US7439079B2 (en) 2005-04-29 2008-10-21 Kimberly-Clark Worldwide, Inc. Assay devices having detection capabilities within the hook effect region
US7803319B2 (en) 2005-04-29 2010-09-28 Kimberly-Clark Worldwide, Inc. Metering technique for lateral flow assay devices
US7504235B2 (en) * 2005-08-31 2009-03-17 Kimberly-Clark Worldwide, Inc. Enzyme detection technique
EP1920253A2 (en) 2005-08-31 2008-05-14 Kimberly-Clark Worldwide, Inc. Detection of proteases secreted from pathogenic microorganisms
US8003399B2 (en) * 2005-08-31 2011-08-23 Kimberly-Clark Worldwide, Inc. Nitrite detection technique

Also Published As

Publication number Publication date
EP2092332B1 (en) 2014-01-15
US7935538B2 (en) 2011-05-03
WO2008075216A1 (en) 2008-06-26
JP5296703B2 (ja) 2013-09-25
EP2092332A1 (en) 2009-08-26
KR20090100350A (ko) 2009-09-23
US20080145949A1 (en) 2008-06-19
CN101558301B (zh) 2013-12-11
CN101558301A (zh) 2009-10-14
KR101481189B1 (ko) 2015-01-09
JP2010513857A (ja) 2010-04-30

Similar Documents

Publication Publication Date Title
EP2092332B1 (en) Indicator immobilization on assay devices
EP1920251B1 (en) Nitrite detection technique
US7943395B2 (en) Extension of the dynamic detection range of assay devices
US8044257B2 (en) Absorbent article containing lateral flow assay device
US5945345A (en) Device for preventing assay interference using silver or lead to remove the interferant
US8377379B2 (en) Lateral flow assay device
CN101896621B (zh) 用于分析物检测的多层装置
EP1573330B1 (en) Self-calibrated flow-through assay devices
US20050191704A1 (en) Assay devices utilizing chemichromic dyes
KR20060126964A (ko) 분석 장치의 동적 검출 범위의 확장 방법
CN111033237A (zh) 使用剂量响应曲线的递减信号部分来测量包括高浓度分析物在内的分析物的夹心式测定
CN107430120A (zh) 免疫检测方法和用于其的测试条
CN111480078A (zh) 免疫层析装置
CA1289471C (en) Dry test strip for devices using oxygen demanding detection system
US7713748B2 (en) Method of reducing the sensitivity of assay devices
MXPA06005123A (en) Method for extending the dynamic detection range of assay devices

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20150929