CA2641632A1 - Novel spiro[imidazolidine-4,3'-indole]-2,2',5(1'h)-triones for treatment of conditions associated with vanilloid receptor 1 - Google Patents
Novel spiro[imidazolidine-4,3'-indole]-2,2',5(1'h)-triones for treatment of conditions associated with vanilloid receptor 1 Download PDFInfo
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- CA2641632A1 CA2641632A1 CA002641632A CA2641632A CA2641632A1 CA 2641632 A1 CA2641632 A1 CA 2641632A1 CA 002641632 A CA002641632 A CA 002641632A CA 2641632 A CA2641632 A CA 2641632A CA 2641632 A1 CA2641632 A1 CA 2641632A1
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- pain
- treatment
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- chronic
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77111906P | 2006-02-07 | 2006-02-07 | |
| US60/771,119 | 2006-02-07 | ||
| PCT/SE2007/000107 WO2007091947A2 (en) | 2006-02-07 | 2007-02-06 | Novel spiro[imidazolidine-4,3'-indole]-2,2',5(1'h)-triones for treatment of conditions associated with vanilloid receptor 1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2641632A1 true CA2641632A1 (en) | 2007-08-16 |
Family
ID=38345567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002641632A Abandoned CA2641632A1 (en) | 2006-02-07 | 2007-02-06 | Novel spiro[imidazolidine-4,3'-indole]-2,2',5(1'h)-triones for treatment of conditions associated with vanilloid receptor 1 |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20070185179A1 (https=) |
| EP (1) | EP2013215A4 (https=) |
| JP (1) | JP2009526043A (https=) |
| KR (1) | KR20080094906A (https=) |
| CN (1) | CN101415711A (https=) |
| AR (1) | AR059265A1 (https=) |
| AU (1) | AU2007212786B2 (https=) |
| BR (1) | BRPI0707423A2 (https=) |
| CA (1) | CA2641632A1 (https=) |
| CL (1) | CL2009000523A1 (https=) |
| IL (1) | IL192890A0 (https=) |
| NO (1) | NO20083547L (https=) |
| NZ (1) | NZ571070A (https=) |
| RU (1) | RU2421457C2 (https=) |
| SA (1) | SA07280027B1 (https=) |
| SG (1) | SG169387A1 (https=) |
| TW (1) | TW200801011A (https=) |
| UA (1) | UA93226C2 (https=) |
| UY (1) | UY30132A1 (https=) |
| WO (1) | WO2007091947A2 (https=) |
| ZA (1) | ZA200806407B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2781521A4 (en) | 2011-10-19 | 2015-03-04 | Kowa Co | NEW SPIROINDOLIN COMPOUND AND MEDICAL AGENT THEREFOR |
| TWI586668B (zh) * | 2012-09-06 | 2017-06-11 | 第一三共股份有限公司 | 二螺吡咯啶衍生物之結晶 |
| CN108409746B (zh) * | 2018-05-15 | 2021-08-24 | 中山大学 | 一种含吡咯或吲哚并氮杂环烷结构的手性氧代螺环吲哚类化合物及其消旋体和制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU532110B2 (en) | 1979-11-13 | 1983-09-15 | Ici Ltd. | Spiro(imidazolidine-4,3:-indoline)-2,2:5-trione derivatives |
| ZA806623B (en) * | 1979-11-13 | 1981-12-30 | Ici Ltd | Substituted indoline-2-one derivatives |
| IE52879B1 (en) | 1981-05-12 | 1988-03-30 | Ici Plc | Pharmaceutical spiro-hydantoin derivatives |
| GB8331194D0 (en) | 1982-12-20 | 1983-12-29 | Ici Plc | Chemical process |
| US4611062A (en) * | 1984-03-26 | 1986-09-09 | Imperial Chemical Industries Plc | Process for resolving certain spiro compounds |
| WO1992007830A2 (en) | 1990-10-29 | 1992-05-14 | Pfizer Inc. | Oxindole peptide antagonists |
| HUP0203548A3 (en) * | 1999-07-21 | 2003-04-28 | Astrazeneca Ab | New spirooxindole derivatives, process for their preparation, pharmaceutical compositions containing them and their use |
| US7248802B2 (en) | 2002-11-27 | 2007-07-24 | Nokia Corporation | Distribution of a synchronization signal in an optical communication system |
| TW200508197A (en) | 2003-03-31 | 2005-03-01 | Ucb Sa | Indolone-acetamide derivatives, processes for preparing them and their uses |
| SE0301446D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | New Compounds |
| US7585878B2 (en) | 2003-06-12 | 2009-09-08 | Astellas Pharma Inc. | Benzamide derivative or salt thereof |
| GB0326633D0 (en) * | 2003-11-14 | 2003-12-17 | Merck Sharp & Dohme | Therapeutic agents |
| US7879866B2 (en) | 2004-07-19 | 2011-02-01 | Dorte Xenia Gram | Inhibition of the activity of the capsaicin receptor in the treatment of obesity or obesity-related diseases and disorders |
| WO2007091948A2 (en) * | 2006-02-07 | 2007-08-16 | Astrazeneca Ab | Novel spiro [imidazolidine-4, 3´-indole] 2, 2´,5´(1h) triones for treatment of conditions associated with vanilloid receptor 1 |
-
2007
- 2007-01-31 AR ARP070100412A patent/AR059265A1/es not_active Application Discontinuation
- 2007-01-31 TW TW096103591A patent/TW200801011A/zh unknown
- 2007-02-05 US US11/671,153 patent/US20070185179A1/en not_active Abandoned
- 2007-02-06 AU AU2007212786A patent/AU2007212786B2/en not_active Ceased
- 2007-02-06 SG SG201100854-7A patent/SG169387A1/en unknown
- 2007-02-06 KR KR1020087019272A patent/KR20080094906A/ko not_active Withdrawn
- 2007-02-06 SA SA07280027A patent/SA07280027B1/ar unknown
- 2007-02-06 RU RU2008131905/04A patent/RU2421457C2/ru not_active IP Right Cessation
- 2007-02-06 UY UY30132A patent/UY30132A1/es not_active Application Discontinuation
- 2007-02-06 NZ NZ571070A patent/NZ571070A/en unknown
- 2007-02-06 EP EP07709323A patent/EP2013215A4/en not_active Withdrawn
- 2007-02-06 BR BRPI0707423-9A patent/BRPI0707423A2/pt not_active IP Right Cessation
- 2007-02-06 CA CA002641632A patent/CA2641632A1/en not_active Abandoned
- 2007-02-06 JP JP2008554186A patent/JP2009526043A/ja active Pending
- 2007-02-06 CN CNA2007800125819A patent/CN101415711A/zh active Pending
- 2007-02-06 WO PCT/SE2007/000107 patent/WO2007091947A2/en not_active Ceased
- 2007-06-02 UA UAA200809311A patent/UA93226C2/ru unknown
-
2008
- 2008-07-17 IL IL192890A patent/IL192890A0/en unknown
- 2008-07-23 ZA ZA200806407A patent/ZA200806407B/xx unknown
- 2008-08-14 NO NO20083547A patent/NO20083547L/no not_active Application Discontinuation
- 2008-11-20 US US12/274,837 patent/US7868181B2/en not_active Expired - Fee Related
-
2009
- 2009-03-05 CL CL2009000523A patent/CL2009000523A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SA07280027B1 (ar) | 2010-11-22 |
| AU2007212786A1 (en) | 2007-08-16 |
| AU2007212786A8 (en) | 2010-05-06 |
| IL192890A0 (en) | 2009-02-11 |
| NZ571070A (en) | 2011-07-29 |
| WO2007091947A8 (en) | 2008-08-07 |
| AU2007212786B2 (en) | 2011-06-02 |
| RU2008131905A (ru) | 2010-03-20 |
| EP2013215A2 (en) | 2009-01-14 |
| US7868181B2 (en) | 2011-01-11 |
| ZA200806407B (en) | 2009-04-29 |
| CN101415711A (zh) | 2009-04-22 |
| EP2013215A4 (en) | 2010-09-08 |
| CL2009000523A1 (es) | 2009-07-17 |
| BRPI0707423A2 (pt) | 2011-05-03 |
| RU2421457C2 (ru) | 2011-06-20 |
| NO20083547L (no) | 2008-11-05 |
| WO2007091947A3 (en) | 2007-10-04 |
| SG169387A1 (en) | 2011-03-30 |
| KR20080094906A (ko) | 2008-10-27 |
| JP2009526043A (ja) | 2009-07-16 |
| TW200801011A (en) | 2008-01-01 |
| UY30132A1 (es) | 2009-07-17 |
| US20090137650A1 (en) | 2009-05-28 |
| AR059265A1 (es) | 2008-03-19 |
| WO2007091947A2 (en) | 2007-08-16 |
| UA93226C2 (en) | 2011-01-25 |
| US20070185179A1 (en) | 2007-08-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20130206 |