CA2629683A1 - Medicament for use in connection with cartilage impairment - Google Patents

Medicament for use in connection with cartilage impairment Download PDF

Info

Publication number
CA2629683A1
CA2629683A1 CA002629683A CA2629683A CA2629683A1 CA 2629683 A1 CA2629683 A1 CA 2629683A1 CA 002629683 A CA002629683 A CA 002629683A CA 2629683 A CA2629683 A CA 2629683A CA 2629683 A1 CA2629683 A1 CA 2629683A1
Authority
CA
Canada
Prior art keywords
alpha
use according
acid
ketoglutaric acid
akg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002629683A
Other languages
English (en)
French (fr)
Inventor
Stefan Pierzynowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ENTRESS AB
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2629683A1 publication Critical patent/CA2629683A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002629683A 2005-11-15 2006-11-15 Medicament for use in connection with cartilage impairment Abandoned CA2629683A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US59717205P 2005-11-15 2005-11-15
US60/597,172 2005-11-15
PCT/SE2006/050479 WO2007058612A1 (en) 2005-11-15 2006-11-15 Medicament for use in connection with cartilage impairment

Publications (1)

Publication Number Publication Date
CA2629683A1 true CA2629683A1 (en) 2007-05-24

Family

ID=38048916

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002629683A Abandoned CA2629683A1 (en) 2005-11-15 2006-11-15 Medicament for use in connection with cartilage impairment

Country Status (10)

Country Link
US (2) US20090312427A1 (https=)
EP (1) EP1951218A4 (https=)
JP (1) JP2009515953A (https=)
KR (1) KR20080074182A (https=)
CN (2) CN101309678B (https=)
AU (1) AU2006316059A1 (https=)
BR (1) BRPI0618599A2 (https=)
CA (1) CA2629683A1 (https=)
RU (1) RU2454999C2 (https=)
WO (1) WO2007058612A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101309678B (zh) * 2005-11-15 2011-04-20 安特瑞斯公司 用于与软骨损伤有关的应用的药物
PL226695B1 (pl) 2006-07-03 2017-08-31 Danuta Kruszewska Środek do zastosowania w zapobieganiu i/lub hamowaniu kolonizacji Helicobacter pylori, zastosowanie soli kwasu alfa‑ketoglutarowego z metalami alkalicznymi i ziem alkalicznych do wytwarzania środka leczniczego oraz dodatku do żywności do zapobiegania i/lub hamowania kolonizacji Helicobacter pylori
EP2106791A1 (en) * 2008-03-31 2009-10-07 Biotempt B.V. Glutamine or glutamine-containing dipeptide in a specific dosage for the treatment of inflammation
KR101080271B1 (ko) * 2009-03-31 2011-11-08 주식회사 웰스킨 다이펩타이드를 유효성분으로 포함하는 자외선에 의한 홍반반응 억제용 화장품 조성물
WO2011126163A1 (ko) * 2010-04-08 2011-10-13 주식회사 웰스킨 다이펩타이드를 포함하는 피부 미백용 조성물
CN113018288A (zh) * 2019-12-25 2021-06-25 同济大学 α-酮戊二酸在制备药物中的用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4687782A (en) * 1984-12-10 1987-08-18 Nutri-Fuels Systems, Inc. Nutritional composition for enhancing skeletal muscle adaptation to exercise training
SE9303691D0 (sv) * 1993-11-09 1993-11-09 Gramineer Ab New beverage
AU7984498A (en) * 1997-06-25 1999-01-04 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Serum-free cell growth medium
US6846501B2 (en) * 2000-04-12 2005-01-25 Mid-America Commercialization Corporation Traditional snacks having balanced nutritional profiles
DE10057290B4 (de) * 2000-11-17 2004-01-08 Fresenius Kabi Deutschland Gmbh Enteral zu verabreichendes Supplement zur parenteralen Ernährung oder partiellen enteralen/oralen Ernährung bei kritisch Kranken, chronisch Kranken und Mangelernährten
SE0201713D0 (sv) * 2001-11-23 2002-06-06 Gramineer Internat Ab New methods and use III
RU2211037C1 (ru) * 2001-12-29 2003-08-27 Институт органической и физической химии им. А.Е.Арбузова Казанского научного центра РАН Препарат селективного действия и способ лечения остеоартрозов
AU2003294221A1 (en) * 2002-09-13 2004-04-19 Kenneth E. Miller Method of alleviating pain via inhibition of neurotransmitter synthesis
EP1745791B1 (en) * 2003-05-07 2013-06-26 Osteologix A/S Treating cartilage/bone conditions with water-soluble strontium salts
US20050176807A1 (en) * 2004-02-09 2005-08-11 Friesen Kim G. Composition and method for use in cartilage affecting conditions
JP2005312402A (ja) * 2004-04-30 2005-11-10 Kanazawa Univ Tlo Inc グルタミン酸伝達系を利用した骨・軟骨疾患治療薬の評価方法
PL368573A1 (en) * 2004-06-17 2005-12-27 Sgp & Sons Ab Pharmaceutical compound influencing growth and mineralization processes in the axial and the appendicular skeleton as well as bone diseases of mature years among humans and animals as well as application of the pharmaceutical compound in the process of growth and mineralization of axial and appendicular skeleton and bone diseases of mature years among humans and animals
PL371081A1 (pl) * 2004-11-08 2006-05-15 Sgp & Sons Ab Preparat farmaceutyczny wpływający na procesy wzrostu i mineralizacji układu kostno-szkieletowego oraz chorób kości i chrząstki wieku dojrzałego u ludzi i zwierząt oraz zastosowanie preparatu farmaceutycznego w procesie wzrostu i mineralizacji układu kostno-szkieletowego oraz chorób kości i chrząstki wieku dojrzałego u ludzi i zwierząt
CN101309678B (zh) * 2005-11-15 2011-04-20 安特瑞斯公司 用于与软骨损伤有关的应用的药物

Also Published As

Publication number Publication date
EP1951218A1 (en) 2008-08-06
HK1126128A1 (en) 2009-08-28
EP1951218A4 (en) 2010-11-10
WO2007058612A1 (en) 2007-05-24
BRPI0618599A2 (pt) 2011-09-06
CN101309678A (zh) 2008-11-19
CN101843609A (zh) 2010-09-29
AU2006316059A1 (en) 2007-05-24
RU2454999C2 (ru) 2012-07-10
CN101309678B (zh) 2011-04-20
RU2008123806A (ru) 2009-12-27
KR20080074182A (ko) 2008-08-12
US20090312427A1 (en) 2009-12-17
US20110082086A1 (en) 2011-04-07
JP2009515953A (ja) 2009-04-16

Similar Documents

Publication Publication Date Title
US20110082086A1 (en) Medicament for use in connection with cartilage impairment
KR20010023795A (ko) 피티에이치알피 유사체를 사용하는 골절 치료법
US20070004629A1 (en) K9 and equine joint health food supplement and method of administering
JP4447913B2 (ja) オステオポローシス治療のための組成物の製造のためのグルタミン酸塩、グルタミン酸塩誘導体又はグルタミン酸塩代謝物、グルタミン酸塩アナログ或いはそれらの混合物の使用
CA2380367A1 (en) Compositions for providing zinc through oral administration
JP4927721B2 (ja) α−ケトグルタル酸及び関連化合物の血漿中脂質を低下させるための使用
KR100304312B1 (ko) 아연이보충된전립선추출물
US20160310578A1 (en) Method of accelerating osteogenesis
WO2012125524A1 (en) Compositions and methods for the treatment of musculoskeletal related diseases and disorders using metal ion-citrate analog complexes
MX2008006203A (en) Medicament for use in connection with cartilage impairment
HK1145285A (en) Medicament for use in connection with cartilage impairment
HK1126128B (en) Medicament for use in connection with cartilage impairment
RU2497527C2 (ru) Фармацевтическая композиция для лечения расстройств, включающих раздражение желудочно-кишечного тракта
KR102276379B1 (ko) IF1 (ATPase inhibitory factor 1)을 유효성분으로 함유하는 골질환의 예방 또는 치료용 약학 조성물
JP4340042B2 (ja) 軟骨生成促進剤及び軟骨損傷由来疾病予防治療剤
KR20060127977A (ko) 지방이상증 치료용 조성물 및 치료 방법
JP2003192584A (ja) 高血圧症予防・改善用組成物
JP3752344B2 (ja) 抗骨粗鬆症剤
JP2018535187A (ja) 選択的関節形成術を受けた患者の疼痛の治療のための組成物
JP2024539038A (ja) 軟骨保護栄養補助食品組成物及びその使用方法
CN119745043A (zh) 一种改善骨关节健康的组合物及其应用
EP1374904A1 (en) Preparation containing polymethyl-siloxane for nails, cartilage, bone joint, muscle and tendon disorders
JP2009084197A (ja) 内因性オピオイドペプチドの血中分泌促進用組成物
WO1997036911A1 (en) Process for producing dissolved hard tissues and hard tissues thus dissolved

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20140319