CN101843609A - 用于与软骨损伤有关的应用的药物 - Google Patents

用于与软骨损伤有关的应用的药物 Download PDF

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Publication number
CN101843609A
CN101843609A CN201010170906A CN201010170906A CN101843609A CN 101843609 A CN101843609 A CN 101843609A CN 201010170906 A CN201010170906 A CN 201010170906A CN 201010170906 A CN201010170906 A CN 201010170906A CN 101843609 A CN101843609 A CN 101843609A
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CN
China
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akg
sham
tong wuersuan
application
placebo
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CN201010170906A
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English (en)
Chinese (zh)
Inventor
斯特凡·皮尔齐诺斯基
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ENTRESS AB
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ENTRESS AB
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Publication of CN101843609A publication Critical patent/CN101843609A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201010170906A 2005-11-15 2006-11-15 用于与软骨损伤有关的应用的药物 Pending CN101843609A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59717205P 2005-11-15 2005-11-15
US60/597,172 2005-11-15

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN2006800426722A Division CN101309678B (zh) 2005-11-15 2006-11-15 用于与软骨损伤有关的应用的药物

Publications (1)

Publication Number Publication Date
CN101843609A true CN101843609A (zh) 2010-09-29

Family

ID=38048916

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201010170906A Pending CN101843609A (zh) 2005-11-15 2006-11-15 用于与软骨损伤有关的应用的药物
CN2006800426722A Expired - Fee Related CN101309678B (zh) 2005-11-15 2006-11-15 用于与软骨损伤有关的应用的药物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN2006800426722A Expired - Fee Related CN101309678B (zh) 2005-11-15 2006-11-15 用于与软骨损伤有关的应用的药物

Country Status (10)

Country Link
US (2) US20090312427A1 (https=)
EP (1) EP1951218A4 (https=)
JP (1) JP2009515953A (https=)
KR (1) KR20080074182A (https=)
CN (2) CN101843609A (https=)
AU (1) AU2006316059A1 (https=)
BR (1) BRPI0618599A2 (https=)
CA (1) CA2629683A1 (https=)
RU (1) RU2454999C2 (https=)
WO (1) WO2007058612A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113018288A (zh) * 2019-12-25 2021-06-25 同济大学 α-酮戊二酸在制备药物中的用途

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006316059A1 (en) * 2005-11-15 2007-05-24 Entress Ab Medicament for use in connection with cartilage impairment
PL226695B1 (pl) 2006-07-03 2017-08-31 Danuta Kruszewska Środek do zastosowania w zapobieganiu i/lub hamowaniu kolonizacji Helicobacter pylori, zastosowanie soli kwasu alfa‑ketoglutarowego z metalami alkalicznymi i ziem alkalicznych do wytwarzania środka leczniczego oraz dodatku do żywności do zapobiegania i/lub hamowania kolonizacji Helicobacter pylori
EP2106791A1 (en) * 2008-03-31 2009-10-07 Biotempt B.V. Glutamine or glutamine-containing dipeptide in a specific dosage for the treatment of inflammation
KR101080271B1 (ko) * 2009-03-31 2011-11-08 주식회사 웰스킨 다이펩타이드를 유효성분으로 포함하는 자외선에 의한 홍반반응 억제용 화장품 조성물
WO2011126163A1 (ko) * 2010-04-08 2011-10-13 주식회사 웰스킨 다이펩타이드를 포함하는 피부 미백용 조성물

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4687782A (en) * 1984-12-10 1987-08-18 Nutri-Fuels Systems, Inc. Nutritional composition for enhancing skeletal muscle adaptation to exercise training
SE9303691D0 (sv) * 1993-11-09 1993-11-09 Gramineer Ab New beverage
WO1998059035A2 (en) * 1997-06-25 1998-12-30 The Goverment Of The United States Of America, Represented By The Secretary, Dept. Of Health And Human Services, National Institutes Of Health Serum-free cell growth medium
US6846501B2 (en) * 2000-04-12 2005-01-25 Mid-America Commercialization Corporation Traditional snacks having balanced nutritional profiles
DE10057290B4 (de) * 2000-11-17 2004-01-08 Fresenius Kabi Deutschland Gmbh Enteral zu verabreichendes Supplement zur parenteralen Ernährung oder partiellen enteralen/oralen Ernährung bei kritisch Kranken, chronisch Kranken und Mangelernährten
SE0201713D0 (sv) * 2001-11-23 2002-06-06 Gramineer Internat Ab New methods and use III
RU2211037C1 (ru) * 2001-12-29 2003-08-27 Институт органической и физической химии им. А.Е.Арбузова Казанского научного центра РАН Препарат селективного действия и способ лечения остеоартрозов
WO2004028448A2 (en) * 2002-09-13 2004-04-08 Miller Kenneth E Method of alleviating pain via inhibition of neurotransmitter synthesis
ES2275218T3 (es) * 2003-05-07 2007-06-01 Osteologix A/S Sales de estroncio hidrosolubles para el tratamiento de afecciones de cartilagos y/o huesos.
US20050176807A1 (en) * 2004-02-09 2005-08-11 Friesen Kim G. Composition and method for use in cartilage affecting conditions
JP2005312402A (ja) * 2004-04-30 2005-11-10 Kanazawa Univ Tlo Inc グルタミン酸伝達系を利用した骨・軟骨疾患治療薬の評価方法
PL368573A1 (en) * 2004-06-17 2005-12-27 Sgp & Sons Ab Pharmaceutical compound influencing growth and mineralization processes in the axial and the appendicular skeleton as well as bone diseases of mature years among humans and animals as well as application of the pharmaceutical compound in the process of growth and mineralization of axial and appendicular skeleton and bone diseases of mature years among humans and animals
PL371081A1 (pl) * 2004-11-08 2006-05-15 Sgp & Sons Ab Preparat farmaceutyczny wpływający na procesy wzrostu i mineralizacji układu kostno-szkieletowego oraz chorób kości i chrząstki wieku dojrzałego u ludzi i zwierząt oraz zastosowanie preparatu farmaceutycznego w procesie wzrostu i mineralizacji układu kostno-szkieletowego oraz chorób kości i chrząstki wieku dojrzałego u ludzi i zwierząt
AU2006316059A1 (en) * 2005-11-15 2007-05-24 Entress Ab Medicament for use in connection with cartilage impairment

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113018288A (zh) * 2019-12-25 2021-06-25 同济大学 α-酮戊二酸在制备药物中的用途
WO2021129649A1 (zh) * 2019-12-25 2021-07-01 同济大学 α-酮戊二酸在制备药物中的用途

Also Published As

Publication number Publication date
EP1951218A4 (en) 2010-11-10
BRPI0618599A2 (pt) 2011-09-06
CA2629683A1 (en) 2007-05-24
CN101309678B (zh) 2011-04-20
RU2454999C2 (ru) 2012-07-10
CN101309678A (zh) 2008-11-19
US20110082086A1 (en) 2011-04-07
WO2007058612A1 (en) 2007-05-24
US20090312427A1 (en) 2009-12-17
KR20080074182A (ko) 2008-08-12
HK1126128A1 (en) 2009-08-28
RU2008123806A (ru) 2009-12-27
JP2009515953A (ja) 2009-04-16
AU2006316059A1 (en) 2007-05-24
EP1951218A1 (en) 2008-08-06

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