CA2613114C - Microneedle cartridge assembly and method of applying - Google Patents
Microneedle cartridge assembly and method of applying Download PDFInfo
- Publication number
- CA2613114C CA2613114C CA2613114A CA2613114A CA2613114C CA 2613114 C CA2613114 C CA 2613114C CA 2613114 A CA2613114 A CA 2613114A CA 2613114 A CA2613114 A CA 2613114A CA 2613114 C CA2613114 C CA 2613114C
- Authority
- CA
- Canada
- Prior art keywords
- microneedle array
- web
- microneedle
- container
- cartridge
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title description 9
- 239000000463 material Substances 0.000 claims abstract description 67
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- 210000003491 skin Anatomy 0.000 description 21
- -1 vaccines Substances 0.000 description 16
- 238000003491 array Methods 0.000 description 11
- 239000003814 drug Substances 0.000 description 10
- 230000037317 transdermal delivery Effects 0.000 description 10
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- 229940079593 drug Drugs 0.000 description 5
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- 239000006260 foam Substances 0.000 description 3
- 150000002605 large molecules Chemical class 0.000 description 3
- 229920002521 macromolecule Polymers 0.000 description 3
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- 229920006254 polymer film Polymers 0.000 description 3
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- 239000007788 liquid Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000002493 microarray Methods 0.000 description 2
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- 229920000139 polyethylene terephthalate Polymers 0.000 description 2
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- 229940021747 therapeutic vaccine Drugs 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- 229940122361 Bisphosphonate Drugs 0.000 description 1
- 108010041986 DNA Vaccines Proteins 0.000 description 1
- 229940021995 DNA vaccine Drugs 0.000 description 1
- 239000001856 Ethyl cellulose Substances 0.000 description 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 244000043261 Hevea brasiliensis Species 0.000 description 1
- 108091028043 Nucleic acid sequence Proteins 0.000 description 1
- 229920002367 Polyisobutene Polymers 0.000 description 1
- 229920001328 Polyvinylidene chloride Polymers 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 150000001241 acetals Chemical class 0.000 description 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 description 1
- 229920006397 acrylic thermoplastic Polymers 0.000 description 1
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000012790 adhesive layer Substances 0.000 description 1
- DCSBSVSZJRSITC-UHFFFAOYSA-M alendronate sodium trihydrate Chemical compound O.O.O.[Na+].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O DCSBSVSZJRSITC-UHFFFAOYSA-M 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 150000004663 bisphosphonates Chemical class 0.000 description 1
- 239000012876 carrier material Substances 0.000 description 1
- VAAUVRVFOQPIGI-SPQHTLEESA-N ceftriaxone Chemical compound S([C@@H]1[C@@H](C(N1C=1C(O)=O)=O)NC(=O)\C(=N/OC)C=2N=C(N)SC=2)CC=1CSC1=NC(=O)C(=O)NN1C VAAUVRVFOQPIGI-SPQHTLEESA-N 0.000 description 1
- 229960004755 ceftriaxone Drugs 0.000 description 1
- 229920002301 cellulose acetate Polymers 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 229920001249 ethyl cellulose Polymers 0.000 description 1
- 235000019325 ethyl cellulose Nutrition 0.000 description 1
- 229920002313 fluoropolymer Polymers 0.000 description 1
- 239000004811 fluoropolymer Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 229920001903 high density polyethylene Polymers 0.000 description 1
- 239000004700 high-density polyethylene Substances 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 238000007373 indentation Methods 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 229920000092 linear low density polyethylene Polymers 0.000 description 1
- 239000004707 linear low-density polyethylene Substances 0.000 description 1
- 229920001684 low density polyethylene Polymers 0.000 description 1
- 239000004702 low-density polyethylene Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229920005690 natural copolymer Polymers 0.000 description 1
- 229920003052 natural elastomer Polymers 0.000 description 1
- 229920001194 natural rubber Polymers 0.000 description 1
- 210000000944 nerve tissue Anatomy 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920001707 polybutylene terephthalate Polymers 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 229920006389 polyphenyl polymer Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000005033 polyvinylidene chloride Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 150000003839 salts Chemical group 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 229920003051 synthetic elastomer Polymers 0.000 description 1
- 239000005061 synthetic rubber Substances 0.000 description 1
- ISXSCDLOGDJUNJ-UHFFFAOYSA-N tert-butyl prop-2-enoate Chemical compound CC(C)(C)OC(=O)C=C ISXSCDLOGDJUNJ-UHFFFAOYSA-N 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 150000003568 thioethers Chemical class 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 238000013271 transdermal drug delivery Methods 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 239000012646 vaccine adjuvant Substances 0.000 description 1
- 229940124931 vaccine adjuvant Drugs 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Packages (AREA)
- Wrappers (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69444605P | 2005-06-27 | 2005-06-27 | |
| US60/694,446 | 2005-06-27 | ||
| PCT/US2006/024672 WO2007002522A1 (en) | 2005-06-27 | 2006-06-23 | Microneedle cartridge assembly and method of applying |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2613114A1 CA2613114A1 (en) | 2007-01-04 |
| CA2613114C true CA2613114C (en) | 2015-02-24 |
Family
ID=37103001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2613114A Expired - Fee Related CA2613114C (en) | 2005-06-27 | 2006-06-23 | Microneedle cartridge assembly and method of applying |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20100256568A1 (https=) |
| EP (1) | EP1896115B2 (https=) |
| JP (2) | JP2008543528A (https=) |
| CN (1) | CN101208129B (https=) |
| AT (1) | ATE477833T1 (https=) |
| AU (1) | AU2006261899B2 (https=) |
| CA (1) | CA2613114C (https=) |
| DE (1) | DE602006016279D1 (https=) |
| WO (1) | WO2007002522A1 (https=) |
Families Citing this family (110)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0402131D0 (en) | 2004-01-30 | 2004-03-03 | Isis Innovation | Delivery method |
| AU2008241470B2 (en) | 2007-04-16 | 2013-11-07 | Corium Pharma Solutions, Inc. | Solvent-cast microneedle arrays containing active |
| JP2012509106A (ja) | 2008-11-18 | 2012-04-19 | スリーエム イノベイティブ プロパティズ カンパニー | 中空のマイクロニードルアレイ及び方法 |
| CN102405018B (zh) | 2009-03-02 | 2014-11-19 | 第七感生物系统有限公司 | 与血液取样相关联的技术和装置 |
| US9295417B2 (en) | 2011-04-29 | 2016-03-29 | Seventh Sense Biosystems, Inc. | Systems and methods for collecting fluid from a subject |
| US9041541B2 (en) | 2010-01-28 | 2015-05-26 | Seventh Sense Biosystems, Inc. | Monitoring or feedback systems and methods |
| WO2012018486A2 (en) | 2010-07-26 | 2012-02-09 | Seventh Sense Biosystems, Inc. | Rapid delivery and/or receiving of fluids |
| JP5860033B2 (ja) | 2010-04-28 | 2016-02-16 | キンバリー クラーク ワールドワイド インコーポレイテッド | ｓｉＲＮＡ送達用の医療デバイス |
| EP2563455A4 (en) | 2010-04-28 | 2014-02-19 | Kimberly Clark Co | METHOD FOR INCREASING THE PERMEABILITY OF AN EPITHELIAL BARRIER |
| MX2012012317A (es) | 2010-04-28 | 2012-11-21 | Kimberly Clark Co | Arreglo de microagujas moldeado por inyeccion y metodo para formar el arreglo de microagujas. |
| CA2797204C (en) | 2010-04-28 | 2018-06-12 | Kimberly-Clark Worldwide, Inc. | Device for delivery of rheumatoid arthritis medication |
| EP2566568B1 (en) | 2010-05-04 | 2019-04-10 | Corium International, Inc. | Applicators for microneedles |
| WO2011140274A2 (en) | 2010-05-04 | 2011-11-10 | Corium International, Inc. | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
| WO2011163347A2 (en) | 2010-06-23 | 2011-12-29 | Seventh Sense Biosystems, Inc. | Sampling devices and methods involving relatively little pain |
| WO2012009613A1 (en) | 2010-07-16 | 2012-01-19 | Seventh Sense Biosystems, Inc. | Low-pressure environment for fluid transfer devices |
| WO2012021801A2 (en) | 2010-08-13 | 2012-02-16 | Seventh Sense Biosystems, Inc. | Systems and techniques for monitoring subjects |
| EP2992827B1 (en) | 2010-11-09 | 2017-04-19 | Seventh Sense Biosystems, Inc. | Systems and interfaces for blood sampling |
| JP6082697B2 (ja) * | 2010-12-22 | 2017-02-15 | バレリタス， インコーポレイテッド | 極微針パッチアプリケータ |
| US8696637B2 (en) | 2011-02-28 | 2014-04-15 | Kimberly-Clark Worldwide | Transdermal patch containing microneedles |
| JP5687170B2 (ja) * | 2011-03-30 | 2015-03-18 | コスメディ製薬株式会社 | マイクロニードルパッチ収納容器 |
| CN103874460B (zh) | 2011-04-29 | 2016-06-22 | 第七感生物系统有限公司 | 一种用于从受验者的皮肤接收血液或其它物质的装置 |
| US20130158468A1 (en) | 2011-12-19 | 2013-06-20 | Seventh Sense Biosystems, Inc. | Delivering and/or receiving material with respect to a subject surface |
| KR20140034200A (ko) | 2011-04-29 | 2014-03-19 | 세븐쓰 센스 바이오시스템즈, 인크. | 혈액 스폿들 또는 다른 신체 유체들을 수집 및/또는 조작하기 위한 시스템들 및 방법들 |
| WO2013053022A1 (en) | 2011-10-12 | 2013-04-18 | The University Of Queensland | Delivery device |
| CN103874518A (zh) | 2011-10-12 | 2014-06-18 | 3M创新有限公司 | 一体化微针阵列递送系统 |
| MX343262B (es) | 2011-10-27 | 2016-10-28 | Kimberly Clark Co | Administración transdérmica de agentes bioactivos de alta viscosidad. |
| US20170246439A9 (en) | 2011-10-27 | 2017-08-31 | Kimberly-Clark Worldwide, Inc. | Increased Bioavailability of Transdermally Delivered Agents |
| JP5903016B2 (ja) | 2012-06-27 | 2016-04-13 | コスメディ製薬株式会社 | マイクロニードルパッチの保護離型シート |
| JP6418544B2 (ja) * | 2012-06-27 | 2018-11-07 | コスメディ製薬株式会社 | マイクロニードルパッチの保護離型シート |
| JP5719005B2 (ja) * | 2012-09-27 | 2015-05-13 | コスメディ製薬株式会社 | マイクロニードルパッチ収納容器２ |
| US20140100530A1 (en) | 2012-10-05 | 2014-04-10 | Miguel A. Linares | Attachable uterine device with integrated and time release medicinal administering component and insertion tool for implanting such a device |
| EP2919849B1 (en) | 2012-11-16 | 2021-01-06 | Kindeva Drug Delivery L.P. | Force-controlled applicator for applying a microneedle device to skin |
| JP6111634B2 (ja) * | 2012-12-10 | 2017-04-12 | 凸版印刷株式会社 | 針状構造体の製造装置 |
| JP6865524B2 (ja) | 2012-12-21 | 2021-04-28 | コリウム， インコーポレイテッド | 治療剤を送達するためのマイクロアレイおよび使用方法 |
| KR102219636B1 (ko) | 2012-12-27 | 2021-02-23 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 중공형 마이크로니들을 갖는 물품 및 제조 방법 |
| US20150352295A1 (en) | 2013-01-08 | 2015-12-10 | 3M Innovative Properties Company | Application For Applying A Microneedle Device To Skin |
| CN103157178B (zh) * | 2013-02-05 | 2014-12-31 | 北京化工大学 | 精确控制微针插入长度的印章式工具 |
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2006
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- 2006-06-23 JP JP2008519436A patent/JP2008543528A/ja not_active Withdrawn
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| EP1896115B1 (en) | 2010-08-18 |
| US20100256568A1 (en) | 2010-10-07 |
| EP1896115B2 (en) | 2020-01-22 |
| US10307578B2 (en) | 2019-06-04 |
| CN101208129B (zh) | 2011-03-30 |
| EP1896115A1 (en) | 2008-03-12 |
| JP5676548B2 (ja) | 2015-02-25 |
| JP2013066730A (ja) | 2013-04-18 |
| JP2008543528A (ja) | 2008-12-04 |
| CA2613114A1 (en) | 2007-01-04 |
| CN101208129A (zh) | 2008-06-25 |
| DE602006016279D1 (de) | 2010-09-30 |
| AU2006261899B2 (en) | 2012-05-10 |
| US20190240470A1 (en) | 2019-08-08 |
| US20170266428A1 (en) | 2017-09-21 |
| AU2006261899A1 (en) | 2007-01-04 |
| ATE477833T1 (de) | 2010-09-15 |
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