CA2608195A1 - Nebulization of monoclonal antibodies for treating pulmonary diseases - Google Patents
Nebulization of monoclonal antibodies for treating pulmonary diseases Download PDFInfo
- Publication number
- CA2608195A1 CA2608195A1 CA002608195A CA2608195A CA2608195A1 CA 2608195 A1 CA2608195 A1 CA 2608195A1 CA 002608195 A CA002608195 A CA 002608195A CA 2608195 A CA2608195 A CA 2608195A CA 2608195 A1 CA2608195 A1 CA 2608195A1
- Authority
- CA
- Canada
- Prior art keywords
- antibody
- nebulizer
- active agent
- pulmonary
- airway
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/544—Mucosal route to the airways
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/127,438 US20050271660A1 (en) | 2002-09-06 | 2005-05-11 | Nebulization of monoclonal antibodies for treating pulmonary diseases |
| US11/127,438 | 2005-05-11 | ||
| PCT/US2006/018269 WO2006122257A2 (en) | 2005-05-11 | 2006-05-10 | Nebulization of monoclonal antibodies for treating pulmonary diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2608195A1 true CA2608195A1 (en) | 2006-11-16 |
Family
ID=37054603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002608195A Abandoned CA2608195A1 (en) | 2005-05-11 | 2006-05-10 | Nebulization of monoclonal antibodies for treating pulmonary diseases |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US20050271660A1 (https=) |
| EP (1) | EP1881993A2 (https=) |
| JP (3) | JP2008540563A (https=) |
| AU (1) | AU2006243994B2 (https=) |
| CA (1) | CA2608195A1 (https=) |
| NZ (2) | NZ582627A (https=) |
| WO (1) | WO2006122257A2 (https=) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050271660A1 (en) | 2002-09-06 | 2005-12-08 | Alexion Pharmaceuticals, Inc. | Nebulization of monoclonal antibodies for treating pulmonary diseases |
| WO2004022096A1 (en) * | 2002-09-06 | 2004-03-18 | Alexion Pharmaceuticals, Inc. | Method of treatment of asthma using antibodies to complement component c5 |
| US9415102B2 (en) | 2002-09-06 | 2016-08-16 | Alexion Pharmaceuticals, Inc. | High concentration formulations of anti-C5 antibodies |
| WO2010081856A1 (en) * | 2009-01-14 | 2010-07-22 | Ablynx Nv | Pulmonary administration of immunoglobulin single variable domains and constructs thereof |
| US9320792B2 (en) | 2002-11-08 | 2016-04-26 | Ablynx N.V. | Pulmonary administration of immunoglobulin single variable domains and constructs thereof |
| WO2005048982A2 (en) * | 2003-11-17 | 2005-06-02 | Nektar Therapeutics | Efficient introduction of an aerosol into a ventilator circuit |
| ES2432112T3 (es) | 2004-02-10 | 2013-11-29 | The Regents Of The University Of Colorado, A Body Corporate | Inhibición del factor B, de la vía alternativa del complemento y métodos relacionados |
| DK1817340T3 (da) | 2004-11-12 | 2012-08-13 | Xencor Inc | Fc-varianter med ændret binding til fcrn |
| CA2610340C (en) | 2005-05-26 | 2016-02-16 | Vernon Michael Holers | Inhibition of the alternative complement pathway for treatment of traumatic brain injury, spinal cord injury and related conditions |
| US20070191262A1 (en) * | 2005-11-15 | 2007-08-16 | University Of Iowa Research Foundation | Cancer Therapy and Prevention Based on Modulation of Complement activity |
| PL3167888T3 (pl) | 2006-03-15 | 2024-08-26 | Alexion Pharmaceuticals, Inc. | Leczenie pacjentów z napadową nocną hemoglobinurią za pomocą inhibitora dopełniacza |
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-
2005
- 2005-05-11 US US11/127,438 patent/US20050271660A1/en not_active Abandoned
-
2006
- 2006-05-10 WO PCT/US2006/018269 patent/WO2006122257A2/en not_active Ceased
- 2006-05-10 CA CA002608195A patent/CA2608195A1/en not_active Abandoned
- 2006-05-10 NZ NZ582627A patent/NZ582627A/en unknown
- 2006-05-10 JP JP2008511366A patent/JP2008540563A/ja not_active Withdrawn
- 2006-05-10 NZ NZ563509A patent/NZ563509A/en not_active IP Right Cessation
- 2006-05-10 AU AU2006243994A patent/AU2006243994B2/en not_active Ceased
- 2006-05-10 EP EP06759586A patent/EP1881993A2/en not_active Withdrawn
-
2012
- 2012-09-04 JP JP2012193985A patent/JP2012233013A/ja active Pending
-
2014
- 2014-06-19 JP JP2014125985A patent/JP2014169332A/ja active Pending
-
2017
- 2017-08-11 US US15/675,074 patent/US10125191B2/en not_active Expired - Lifetime
-
2018
- 2018-10-04 US US16/152,235 patent/US10479828B2/en not_active Expired - Lifetime
-
2019
- 2019-10-09 US US16/597,040 patent/US10927166B2/en not_active Expired - Lifetime
-
2021
- 2021-01-19 US US17/152,054 patent/US20210214427A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20050271660A1 (en) | 2005-12-08 |
| US10125191B2 (en) | 2018-11-13 |
| US20210214427A1 (en) | 2021-07-15 |
| AU2006243994A1 (en) | 2006-11-16 |
| JP2012233013A (ja) | 2012-11-29 |
| EP1881993A2 (en) | 2008-01-30 |
| NZ563509A (en) | 2010-10-29 |
| US20170355759A1 (en) | 2017-12-14 |
| US20200102379A1 (en) | 2020-04-02 |
| AU2006243994B2 (en) | 2012-03-01 |
| WO2006122257A3 (en) | 2007-02-01 |
| US10479828B2 (en) | 2019-11-19 |
| JP2014169332A (ja) | 2014-09-18 |
| US20190092843A1 (en) | 2019-03-28 |
| JP2008540563A (ja) | 2008-11-20 |
| US10927166B2 (en) | 2021-02-23 |
| NZ582627A (en) | 2011-11-25 |
| WO2006122257A2 (en) | 2006-11-16 |
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