CA2579753C - Lentivirus non integratif et non replicatif, preparation et utilisations - Google Patents
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- CA2579753C CA2579753C CA2579753A CA2579753A CA2579753C CA 2579753 C CA2579753 C CA 2579753C CA 2579753 A CA2579753 A CA 2579753A CA 2579753 A CA2579753 A CA 2579753A CA 2579753 C CA2579753 C CA 2579753C
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| FR0407017 | 2004-06-25 | ||
| PCT/FR2005/001604 WO2006010834A1 (fr) | 2004-06-25 | 2005-06-24 | Lentivirus non integratif et non replicatif, preparation et utilisations |
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| CA2579753A1 CA2579753A1 (fr) | 2006-02-02 |
| CA2579753C true CA2579753C (fr) | 2015-04-14 |
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| AU2013203404B2 (en) * | 2007-08-03 | 2016-10-13 | Centre National De La Recherche Scientifique (Cnrs) | Lentiviral gene transfer vectors and their medicinal applications |
| EP2020444B1 (en) * | 2007-08-03 | 2017-05-31 | Institut Pasteur | Defective non-integrative lentiviral transfer vectors for vaccines |
| CN102083462B (zh) | 2007-08-03 | 2015-02-18 | 巴斯德研究院 | 慢病毒基因转移载体及其医学应用 |
| CA2703045C (en) | 2007-10-25 | 2017-02-14 | Sangamo Biosciences, Inc. | Methods and compositions for targeted integration |
| US20110142880A1 (en) * | 2008-03-28 | 2011-06-16 | Franck Yann Lemiale | Lentivirus-based immunogenic vectors |
| WO2009131706A1 (en) * | 2008-04-26 | 2009-10-29 | Yung-Nien Chang | Site-specific-integration lentiviral vectors |
| WO2010105251A2 (en) * | 2009-03-13 | 2010-09-16 | Lentigen Corporation | Non-integrating retroviral vector vaccines |
| CA2756833C (en) | 2009-04-09 | 2019-11-19 | Sangamo Biosciences, Inc. | Targeted integration into stem cells |
| US8956828B2 (en) | 2009-11-10 | 2015-02-17 | Sangamo Biosciences, Inc. | Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases |
| CA2788850C (en) | 2010-02-09 | 2019-06-25 | Sangamo Biosciences, Inc. | Targeted genomic modification with partially single-stranded donor molecules |
| DK2385107T3 (en) | 2010-05-03 | 2016-12-12 | Pasteur Institut | Lentiviral vector-based immunological compounds against malaria |
| WO2012152912A1 (en) | 2011-05-12 | 2012-11-15 | Newvectys | Genetically modified pig as a cancer prone model |
| ES2651922T3 (es) | 2011-11-08 | 2018-01-30 | Institut Pasteur | Polipéptidos de afinidad elevada para MAST2 y usos de los mismos |
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| CN104583231B (zh) | 2012-03-30 | 2021-02-26 | 免疫设计公司 | 具有对表达dc-sign的细胞改善的转导效率的慢病毒载体粒子 |
| US9713635B2 (en) | 2012-03-30 | 2017-07-25 | Immune Design Corp. | Materials and methods for producing improved lentiviral vector particles |
| JP2016501531A (ja) | 2012-12-12 | 2016-01-21 | ザ・ブロード・インスティテュート・インコーポレイテッド | 配列操作および治療適用のための系、方法および組成物の送達、エンジニアリングおよび最適化 |
| WO2014093701A1 (en) | 2012-12-12 | 2014-06-19 | The Broad Institute, Inc. | Functional genomics using crispr-cas systems, compositions, methods, knock out libraries and applications thereof |
| ES2701749T3 (es) | 2012-12-12 | 2019-02-25 | Broad Inst Inc | Métodos, modelos, sistemas y aparatos para identificar secuencias diana para enzimas Cas o sistemas CRISPR-Cas para secuencias diana y transmitir resultados de los mismos |
| AU2013204922B2 (en) | 2012-12-20 | 2015-05-14 | Celgene Corporation | Chimeric antigen receptors |
| CN105518018B (zh) | 2013-03-15 | 2020-04-03 | 细胞基因公司 | 修饰的t淋巴细胞 |
| EP3825406A1 (en) | 2013-06-17 | 2021-05-26 | The Broad Institute Inc. | Delivery and use of the crispr-cas systems, vectors and compositions for hepatic targeting and therapy |
| SG10201710487VA (en) * | 2013-06-17 | 2018-01-30 | Broad Inst Inc | Delivery, Use and Therapeutic Applications of the Crispr-Cas Systems and Compositions for Targeting Disorders and Diseases Using Viral Components |
| WO2014204724A1 (en) | 2013-06-17 | 2014-12-24 | The Broad Institute Inc. | Delivery, engineering and optimization of tandem guide systems, methods and compositions for sequence manipulation |
| EP3620524A1 (en) * | 2013-06-17 | 2020-03-11 | The Broad Institute, Inc. | Delivery, engineering and optimization of systems, methods and compositions for targeting and modeling diseases and disorders of post mitotic cells |
| EP3725885A1 (en) | 2013-06-17 | 2020-10-21 | The Broad Institute, Inc. | Functional genomics using crispr-cas systems, compositions methods, screens and applications thereof |
| EP3011030B1 (en) | 2013-06-17 | 2023-11-08 | The Broad Institute, Inc. | Optimized crispr-cas double nickase systems, methods and compositions for sequence manipulation |
| EP3046930A1 (en) * | 2013-09-17 | 2016-07-27 | INSERM - Institut National de la Santé et de la Recherche Médicale | Lentiviral vectors having a mutated integrase protein and uses thereof |
| EP2878667A1 (en) | 2013-11-29 | 2015-06-03 | Institut Pasteur | TAL effector means useful for partial or full deletion of DNA tandem repeats |
| KR20160089530A (ko) | 2013-12-12 | 2016-07-27 | 더 브로드 인스티튜트, 인코퍼레이티드 | Ｈｂｖ 및 바이러스 질병 및 질환을 위한 ｃｒｉｓｐｒｃａｓ 시스템 및 조성물의 전달，용도 및 치료적 적용 |
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| WO2015089364A1 (en) | 2013-12-12 | 2015-06-18 | The Broad Institute Inc. | Crystal structure of a crispr-cas system, and uses thereof |
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| JP3140757B2 (ja) | 1989-02-06 | 2001-03-05 | デイナ・フアーバー・キヤンサー・インステイテユート | パッケージング欠陥ｈｉｖプロウイルス、細胞系及びその使用 |
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| CZ2003784A3 (cs) * | 2000-09-22 | 2003-11-12 | Virxsys Corporation | Zlepšené podmíněně se replikující vektory, způsoby jejich produkce a jejich použití |
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- 2005-06-24 US US11/628,534 patent/US8119119B2/en not_active Expired - Fee Related
- 2005-06-24 CN CNA2005800209389A patent/CN101023177A/zh active Pending
- 2005-06-24 CA CA2579753A patent/CA2579753C/fr not_active Expired - Fee Related
- 2005-06-24 EP EP05779704A patent/EP1761635B1/fr not_active Expired - Lifetime
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- 2005-06-24 WO PCT/FR2005/001604 patent/WO2006010834A1/fr not_active Ceased
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| EP1761635A1 (fr) | 2007-03-14 |
| ATE524554T1 (de) | 2011-09-15 |
| AU2005266221B2 (en) | 2010-06-10 |
| US8119119B2 (en) | 2012-02-21 |
| EP1761635B1 (fr) | 2011-09-14 |
| WO2006010834A1 (fr) | 2006-02-02 |
| FR2872170A1 (fr) | 2005-12-30 |
| US20080089863A1 (en) | 2008-04-17 |
| CA2579753A1 (fr) | 2006-02-02 |
| CN101023177A (zh) | 2007-08-22 |
| IL179740A0 (en) | 2007-05-15 |
| JP4861314B2 (ja) | 2012-01-25 |
| AU2005266221A1 (en) | 2006-02-02 |
| FR2872170B1 (fr) | 2006-11-10 |
| JP2008503230A (ja) | 2008-02-07 |
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