CA2507316A1 - Liposomal glucocorticoids - Google Patents
Liposomal glucocorticoids Download PDFInfo
- Publication number
- CA2507316A1 CA2507316A1 CA002507316A CA2507316A CA2507316A1 CA 2507316 A1 CA2507316 A1 CA 2507316A1 CA 002507316 A CA002507316 A CA 002507316A CA 2507316 A CA2507316 A CA 2507316A CA 2507316 A1 CA2507316 A1 CA 2507316A1
- Authority
- CA
- Canada
- Prior art keywords
- liposomal formulation
- liposomes
- formulation according
- mole
- phosphate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10255106.5 | 2002-11-24 | ||
| DE10255106A DE10255106A1 (de) | 2002-11-24 | 2002-11-24 | Liposomale Glucocorticoide |
| PCT/DE2003/003893 WO2004047792A2 (de) | 2002-11-24 | 2003-11-24 | Liposomale glucocorticoide |
Publications (1)
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| CA2507316A1 true CA2507316A1 (en) | 2004-06-10 |
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|---|---|---|---|
| CA002507316A Abandoned CA2507316A1 (en) | 2002-11-24 | 2003-11-24 | Liposomal glucocorticoids |
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|---|---|
| US (1) | US20060147511A1 (https=) |
| EP (1) | EP1581185B1 (https=) |
| JP (1) | JP2006509750A (https=) |
| CN (1) | CN1731981B (https=) |
| AT (1) | ATE445389T1 (https=) |
| AU (1) | AU2003294635B8 (https=) |
| CA (1) | CA2507316A1 (https=) |
| DE (2) | DE10255106A1 (https=) |
| WO (1) | WO2004047792A2 (https=) |
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| AU2004257375A1 (en) * | 2003-07-21 | 2005-01-27 | Vasogen Ireland Limited | Liposomes containing phosphate glycerol groups for treating acute inflammatory condition |
| EP1793805A1 (en) * | 2004-09-09 | 2007-06-13 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Liposomal formulations comprising an amphipathic weak base like tempamine for treatment of neurodegenerative conditions |
| US7744920B2 (en) * | 2004-09-09 | 2010-06-29 | Hadasit Medical Research Services & Development Limited | Use of liposomal glucocorticoids for treating inflammatory states |
| AU2006256351B2 (en) | 2005-06-10 | 2011-08-04 | Pola Chemical Industries Inc. | Novel triterpenic acid derivative and preparation for external application for skin comprising the same |
| JP4980634B2 (ja) * | 2006-03-17 | 2012-07-18 | ポーラ化成工業株式会社 | 肌荒れの予防、改善に好適な皮膚外用剤 |
| US20080027371A1 (en) * | 2006-07-26 | 2008-01-31 | Higuchi John W | Method and device for minimally invasive site specific ocular drug delivery |
| ES2599630T3 (es) * | 2006-09-28 | 2017-02-02 | Hadasit Medical Research Services & Development Limited | Uso de glicerofosfolípidos para lubricación de las articulaciones |
| JP5424885B2 (ja) * | 2006-10-13 | 2014-02-26 | マリーナ バイオテック，インコーポレイテッド | 両性リポソームにおけるまたは両性リポソームに関する改善、両性リポソームを処方する方法および両性リポソームに充填する方法 |
| CA2702103A1 (en) * | 2007-10-12 | 2009-04-16 | Novosom Ag | Improvements in or relating to amphotaric liposomes comprising neutral lipids |
| EP2127639A1 (en) * | 2008-05-26 | 2009-12-02 | Universiteit Utrecht Holding B.V. | Corticosteroid containing liposomes for treatment of cardiovascular diseases |
| EP2415464B1 (en) * | 2009-03-30 | 2017-05-10 | Eisai R&D Management Co., Ltd. | Method for producing liposome composition |
| ES2593027T3 (es) | 2009-03-30 | 2016-12-05 | Eisai R&D Management Co., Ltd. | Composición liposomal |
| CN102366411B (zh) * | 2011-09-14 | 2012-12-19 | 海南灵康制药有限公司 | 一种地塞米松棕榈酸酯脂质体注射液 |
| PT2773325T (pt) * | 2011-11-04 | 2018-12-19 | Enceladus Pharmaceuticals B V | Corticosteróides lipossômicos para o tratamento de transtornos inflamatórios em humanos |
| EP3095440B1 (en) | 2015-05-19 | 2020-01-15 | PLS-Design GmbH | Antigen-specific immunotherapy using tolerizing liposomes |
| CN106177959A (zh) * | 2016-04-01 | 2016-12-07 | 北京大学 | 抗癌组合物及其制剂和应用 |
| US12029724B2 (en) | 2016-04-28 | 2024-07-09 | Eisai R&D Management Co., Ltd. | Method for inhibiting tumor growth |
| JP2019515925A (ja) * | 2016-04-29 | 2019-06-13 | エンセラドゥス ファーマセウティカルス べー．フェー． | 炎症性病変又は領域に局所注射するためのリポソーム化コルチコステロイド |
| CN111065423B (zh) * | 2017-08-22 | 2022-04-12 | 莫比斯医疗有限公司 | 用于关节润滑的脂质体制剂 |
| EP3787670A1 (en) | 2017-10-18 | 2021-03-10 | Luxembourg Institute of Health (LIH) | Induction of allergen-specific tregs prior to oral or sublingual immunotherapy of food allergy |
| WO2019076478A1 (en) | 2017-10-18 | 2019-04-25 | Luxembourg Institute Of Health (Lih) | OLIGODESOXYNUCLEOTIDES INCORPORATED IN HYDROGEL AS TOLEROGENEOUS ADJUVANT FOR SUB-CUTANEOUS IMMUNOTHERAPY |
| US12083138B2 (en) * | 2018-07-09 | 2024-09-10 | Taiwan Liposome Co., Ltd. | Methods to reduce complications of intra-articular steroid |
| US11083705B2 (en) | 2019-07-26 | 2021-08-10 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition for treating tumor |
| US12036204B2 (en) | 2019-07-26 | 2024-07-16 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition for treating tumor |
| CN110974954B (zh) * | 2019-12-24 | 2021-03-16 | 珠海丽凡达生物技术有限公司 | 一种用于增强核酸疫苗免疫效果的脂质纳米颗粒及其制备方法 |
| CN111494320A (zh) * | 2020-04-24 | 2020-08-07 | 上海交通大学医学院附属仁济医院 | 一种载糖皮质激素的纳米载体及其制备和应用 |
| EP4522178A1 (en) | 2023-01-19 | 2025-03-19 | Moebius Medical Ltd. | A long-acting liposomal composition for treatment of pain in articular disorders |
| CN117357480B (zh) * | 2023-12-08 | 2024-03-29 | 北京中科利华医药研究院有限公司 | 无针经皮注射用组合物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| GB1523965A (en) * | 1976-03-19 | 1978-09-06 | Ici Ltd | Pharmaceutical compositions containing steroids |
| JPS59222410A (ja) * | 1983-06-01 | 1984-12-14 | Terumo Corp | 薬物保持リポソ−ム製剤 |
| JPS61197513A (ja) * | 1985-02-25 | 1986-09-01 | Ichimaru Fuarukosu Kk | 主薬物を内包した安定なリポソ−ムの製剤化法 |
| US5192528A (en) * | 1985-05-22 | 1993-03-09 | Liposome Technology, Inc. | Corticosteroid inhalation treatment method |
| CA2120197A1 (en) * | 1993-04-02 | 1994-10-03 | Kenji Endo | Stable aqueous dispersions containing liposomes |
| US6391336B1 (en) * | 1997-09-22 | 2002-05-21 | Royer Biomedical, Inc. | Inorganic-polymer complexes for the controlled release of compounds including medicinals |
| US6120800A (en) * | 1997-09-25 | 2000-09-19 | Nexstar Pharmaceuticals, Inc. | Vinca-alkaloid vesicles with enhanced efficacy and tumor targeting properties |
| EP1073425A1 (en) * | 1998-04-30 | 2001-02-07 | The University Of Cincinnati | Fibrinogen coated droplets of liquid hydrophobic phases |
| EP1046394A3 (en) * | 1999-04-19 | 2001-10-10 | ImaRx Pharmaceutical Corp. | Novel compositions useful for delivering compounds into a cell |
| ES2327025T3 (es) * | 1999-06-25 | 2009-10-23 | Terumo Kabushiki Kaisha | Liposomas. |
| DE10109897A1 (de) * | 2001-02-21 | 2002-11-07 | Novosom Ag | Fakultativ kationische Liposomen und Verwendung dieser |
| NZ527832A (en) * | 2001-03-13 | 2006-03-31 | Penwest Pharmaceuticals Co | Chronotherapeutic dosage forms |
| EP1371362A1 (en) * | 2002-06-12 | 2003-12-17 | Universiteit Utrecht Holding B.V. | Composition for treatment of inflammatory disorders |
-
2002
- 2002-11-24 DE DE10255106A patent/DE10255106A1/de not_active Withdrawn
-
2003
- 2003-11-24 WO PCT/DE2003/003893 patent/WO2004047792A2/de not_active Ceased
- 2003-11-24 CN CN2003801074820A patent/CN1731981B/zh not_active Expired - Fee Related
- 2003-11-24 DE DE50312034T patent/DE50312034D1/de not_active Expired - Lifetime
- 2003-11-24 AU AU2003294635A patent/AU2003294635B8/en not_active Ceased
- 2003-11-24 AT AT03785534T patent/ATE445389T1/de not_active IP Right Cessation
- 2003-11-24 CA CA002507316A patent/CA2507316A1/en not_active Abandoned
- 2003-11-24 EP EP03785534A patent/EP1581185B1/de not_active Expired - Lifetime
- 2003-11-24 US US10/536,200 patent/US20060147511A1/en not_active Abandoned
- 2003-11-24 JP JP2004554224A patent/JP2006509750A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE50312034D1 (de) | 2009-11-26 |
| CN1731981A (zh) | 2006-02-08 |
| EP1581185A2 (de) | 2005-10-05 |
| AU2003294635A2 (en) | 2004-06-18 |
| US20060147511A1 (en) | 2006-07-06 |
| CN1731981B (zh) | 2010-06-16 |
| DE10255106A1 (de) | 2004-06-09 |
| JP2006509750A (ja) | 2006-03-23 |
| WO2004047792A2 (de) | 2004-06-10 |
| WO2004047792A3 (de) | 2004-08-12 |
| EP1581185B1 (de) | 2009-10-14 |
| ATE445389T1 (de) | 2009-10-15 |
| AU2003294635B2 (en) | 2009-05-28 |
| AU2003294635A1 (en) | 2004-06-18 |
| AU2003294635B8 (en) | 2009-09-17 |
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