ATE445389T1 - Liposomale glucocorticoide - Google Patents

Liposomale glucocorticoide

Info

Publication number
ATE445389T1
ATE445389T1 AT03785534T AT03785534T ATE445389T1 AT E445389 T1 ATE445389 T1 AT E445389T1 AT 03785534 T AT03785534 T AT 03785534T AT 03785534 T AT03785534 T AT 03785534T AT E445389 T1 ATE445389 T1 AT E445389T1
Authority
AT
Austria
Prior art keywords
liposomal
glucocorticoids
formulation
liposomal glucocorticoids
liposomal formulation
Prior art date
Application number
AT03785534T
Other languages
German (de)
English (en)
Inventor
Steffen Panzner
Rolf Braeuer
Raimund Kinne
Una Rauchhaus
Original Assignee
Novosom Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novosom Ag filed Critical Novosom Ag
Application granted granted Critical
Publication of ATE445389T1 publication Critical patent/ATE445389T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT03785534T 2002-11-24 2003-11-24 Liposomale glucocorticoide ATE445389T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10255106A DE10255106A1 (de) 2002-11-24 2002-11-24 Liposomale Glucocorticoide
PCT/DE2003/003893 WO2004047792A2 (de) 2002-11-24 2003-11-24 Liposomale glucocorticoide

Publications (1)

Publication Number Publication Date
ATE445389T1 true ATE445389T1 (de) 2009-10-15

Family

ID=32308712

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03785534T ATE445389T1 (de) 2002-11-24 2003-11-24 Liposomale glucocorticoide

Country Status (9)

Country Link
US (1) US20060147511A1 (https=)
EP (1) EP1581185B1 (https=)
JP (1) JP2006509750A (https=)
CN (1) CN1731981B (https=)
AT (1) ATE445389T1 (https=)
AU (1) AU2003294635B8 (https=)
CA (1) CA2507316A1 (https=)
DE (2) DE10255106A1 (https=)
WO (1) WO2004047792A2 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004257375A1 (en) * 2003-07-21 2005-01-27 Vasogen Ireland Limited Liposomes containing phosphate glycerol groups for treating acute inflammatory condition
EP1793805A1 (en) * 2004-09-09 2007-06-13 Yissum Research Development Company Of The Hebrew University Of Jerusalem Liposomal formulations comprising an amphipathic weak base like tempamine for treatment of neurodegenerative conditions
US7744920B2 (en) * 2004-09-09 2010-06-29 Hadasit Medical Research Services & Development Limited Use of liposomal glucocorticoids for treating inflammatory states
AU2006256351B2 (en) 2005-06-10 2011-08-04 Pola Chemical Industries Inc. Novel triterpenic acid derivative and preparation for external application for skin comprising the same
JP4980634B2 (ja) * 2006-03-17 2012-07-18 ポーラ化成工業株式会社 肌荒れの予防、改善に好適な皮膚外用剤
US20080027371A1 (en) * 2006-07-26 2008-01-31 Higuchi John W Method and device for minimally invasive site specific ocular drug delivery
ES2599630T3 (es) * 2006-09-28 2017-02-02 Hadasit Medical Research Services & Development Limited Uso de glicerofosfolípidos para lubricación de las articulaciones
JP5424885B2 (ja) * 2006-10-13 2014-02-26 マリーナ バイオテック，インコーポレイテッド 両性リポソームにおけるまたは両性リポソームに関する改善、両性リポソームを処方する方法および両性リポソームに充填する方法
CA2702103A1 (en) * 2007-10-12 2009-04-16 Novosom Ag Improvements in or relating to amphotaric liposomes comprising neutral lipids
EP2127639A1 (en) * 2008-05-26 2009-12-02 Universiteit Utrecht Holding B.V. Corticosteroid containing liposomes for treatment of cardiovascular diseases
EP2415464B1 (en) * 2009-03-30 2017-05-10 Eisai R&D Management Co., Ltd. Method for producing liposome composition
ES2593027T3 (es) 2009-03-30 2016-12-05 Eisai R&D Management Co., Ltd. Composición liposomal
CN102366411B (zh) * 2011-09-14 2012-12-19 海南灵康制药有限公司 一种地塞米松棕榈酸酯脂质体注射液
PT2773325T (pt) * 2011-11-04 2018-12-19 Enceladus Pharmaceuticals B V Corticosteróides lipossômicos para o tratamento de transtornos inflamatórios em humanos
EP3095440B1 (en) 2015-05-19 2020-01-15 PLS-Design GmbH Antigen-specific immunotherapy using tolerizing liposomes
CN106177959A (zh) * 2016-04-01 2016-12-07 北京大学 抗癌组合物及其制剂和应用
US12029724B2 (en) 2016-04-28 2024-07-09 Eisai R&D Management Co., Ltd. Method for inhibiting tumor growth
JP2019515925A (ja) * 2016-04-29 2019-06-13 エンセラドゥス ファーマセウティカルス べー．フェー． 炎症性病変又は領域に局所注射するためのリポソーム化コルチコステロイド
CN111065423B (zh) * 2017-08-22 2022-04-12 莫比斯医疗有限公司 用于关节润滑的脂质体制剂
EP3787670A1 (en) 2017-10-18 2021-03-10 Luxembourg Institute of Health (LIH) Induction of allergen-specific tregs prior to oral or sublingual immunotherapy of food allergy
WO2019076478A1 (en) 2017-10-18 2019-04-25 Luxembourg Institute Of Health (Lih) OLIGODESOXYNUCLEOTIDES INCORPORATED IN HYDROGEL AS TOLEROGENEOUS ADJUVANT FOR SUB-CUTANEOUS IMMUNOTHERAPY
US12083138B2 (en) * 2018-07-09 2024-09-10 Taiwan Liposome Co., Ltd. Methods to reduce complications of intra-articular steroid
US11083705B2 (en) 2019-07-26 2021-08-10 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating tumor
US12036204B2 (en) 2019-07-26 2024-07-16 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating tumor
CN110974954B (zh) * 2019-12-24 2021-03-16 珠海丽凡达生物技术有限公司 一种用于增强核酸疫苗免疫效果的脂质纳米颗粒及其制备方法
CN111494320A (zh) * 2020-04-24 2020-08-07 上海交通大学医学院附属仁济医院 一种载糖皮质激素的纳米载体及其制备和应用
EP4522178A1 (en) 2023-01-19 2025-03-19 Moebius Medical Ltd. A long-acting liposomal composition for treatment of pain in articular disorders
CN117357480B (zh) * 2023-12-08 2024-03-29 北京中科利华医药研究院有限公司 无针经皮注射用组合物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523965A (en) * 1976-03-19 1978-09-06 Ici Ltd Pharmaceutical compositions containing steroids
JPS59222410A (ja) * 1983-06-01 1984-12-14 Terumo Corp 薬物保持リポソ−ム製剤
JPS61197513A (ja) * 1985-02-25 1986-09-01 Ichimaru Fuarukosu Kk 主薬物を内包した安定なリポソ−ムの製剤化法
US5192528A (en) * 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
CA2120197A1 (en) * 1993-04-02 1994-10-03 Kenji Endo Stable aqueous dispersions containing liposomes
US6391336B1 (en) * 1997-09-22 2002-05-21 Royer Biomedical, Inc. Inorganic-polymer complexes for the controlled release of compounds including medicinals
US6120800A (en) * 1997-09-25 2000-09-19 Nexstar Pharmaceuticals, Inc. Vinca-alkaloid vesicles with enhanced efficacy and tumor targeting properties
EP1073425A1 (en) * 1998-04-30 2001-02-07 The University Of Cincinnati Fibrinogen coated droplets of liquid hydrophobic phases
EP1046394A3 (en) * 1999-04-19 2001-10-10 ImaRx Pharmaceutical Corp. Novel compositions useful for delivering compounds into a cell
ES2327025T3 (es) * 1999-06-25 2009-10-23 Terumo Kabushiki Kaisha Liposomas.
DE10109897A1 (de) * 2001-02-21 2002-11-07 Novosom Ag Fakultativ kationische Liposomen und Verwendung dieser
NZ527832A (en) * 2001-03-13 2006-03-31 Penwest Pharmaceuticals Co Chronotherapeutic dosage forms
EP1371362A1 (en) * 2002-06-12 2003-12-17 Universiteit Utrecht Holding B.V. Composition for treatment of inflammatory disorders

Also Published As

Publication number Publication date
DE50312034D1 (de) 2009-11-26
CN1731981A (zh) 2006-02-08
EP1581185A2 (de) 2005-10-05
AU2003294635A2 (en) 2004-06-18
US20060147511A1 (en) 2006-07-06
CN1731981B (zh) 2010-06-16
CA2507316A1 (en) 2004-06-10
DE10255106A1 (de) 2004-06-09
JP2006509750A (ja) 2006-03-23
WO2004047792A2 (de) 2004-06-10
WO2004047792A3 (de) 2004-08-12
EP1581185B1 (de) 2009-10-14
AU2003294635B2 (en) 2009-05-28
AU2003294635A1 (en) 2004-06-18
AU2003294635B8 (en) 2009-09-17

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Legal Events

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REN Ceased due to non-payment of the annual fee