ATE516037T1 - Topische formulierung von ivermectin zur behandlung von dermatologischen erkrankungen - Google Patents
Topische formulierung von ivermectin zur behandlung von dermatologischen erkrankungenInfo
- Publication number
- ATE516037T1 ATE516037T1 AT04728811T AT04728811T ATE516037T1 AT E516037 T1 ATE516037 T1 AT E516037T1 AT 04728811 T AT04728811 T AT 04728811T AT 04728811 T AT04728811 T AT 04728811T AT E516037 T1 ATE516037 T1 AT E516037T1
- Authority
- AT
- Austria
- Prior art keywords
- ivermectin
- treatment
- topical formulation
- dermatological diseases
- dermatological
- Prior art date
Links
- AZSNMRSAGSSBNP-XPNPUAGNSA-N 22,23-dihydroavermectin B1a Chemical compound C1C[C@H](C)[C@@H]([C@@H](C)CC)O[C@@]21O[C@H](C\C=C(C)\[C@@H](O[C@@H]1O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C1)[C@@H](C)\C=C\C=C/1[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\1)O)C[C@H]4C2 AZSNMRSAGSSBNP-XPNPUAGNSA-N 0.000 title 1
- AZSNMRSAGSSBNP-UHFFFAOYSA-N 22,23-dihydroavermectin B1a Natural products C1CC(C)C(C(C)CC)OC21OC(CC=C(C)C(OC1OC(C)C(OC3OC(C)C(O)C(OC)C3)C(OC)C1)C(C)C=CC=C1C3(C(C(=O)O4)C=C(C)C(O)C3OC1)O)CC4C2 AZSNMRSAGSSBNP-UHFFFAOYSA-N 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 229960002418 ivermectin Drugs 0.000 title 1
- 239000012049 topical pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0305048A FR2854074B1 (fr) | 2003-04-24 | 2003-04-24 | Utilisation de l'ivermectine pour le traitement de desordres dermatologiques |
| US46899403P | 2003-05-09 | 2003-05-09 | |
| PCT/EP2004/004950 WO2004093886A1 (en) | 2003-04-24 | 2004-04-22 | Topical formulation of ivermectin for the treatment of dermatological conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE516037T1 true ATE516037T1 (de) | 2011-07-15 |
Family
ID=33104376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04728811T ATE516037T1 (de) | 2003-04-24 | 2004-04-22 | Topische formulierung von ivermectin zur behandlung von dermatologischen erkrankungen |
Country Status (11)
| Country | Link |
|---|---|
| US (6) | US8815816B2 (de) |
| KR (1) | KR101291824B1 (de) |
| CN (2) | CN103800353A (de) |
| AR (1) | AR044050A1 (de) |
| AT (1) | ATE516037T1 (de) |
| DK (1) | DK1620113T3 (de) |
| ES (1) | ES2371945T3 (de) |
| FR (1) | FR2854074B1 (de) |
| PT (1) | PT1620113E (de) |
| SI (1) | SI1620113T1 (de) |
| ZA (1) | ZA200507346B (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2867684B1 (fr) * | 2004-03-18 | 2006-05-05 | Galderma Sa | Gel creme contenant de l'ivermectine |
| DE602005020912D1 (de) | 2004-03-18 | 2010-06-10 | Galderma Sa | Ivermectin enthaltende creme |
| FR2883181B1 (fr) * | 2005-03-17 | 2007-05-18 | Galderma Sa | Composition a base d'une avermectine et d'acide azelaique notamment pour le traitement de la rosacee |
| US8791153B2 (en) | 2006-10-12 | 2014-07-29 | Sanofi-Topaz, Inc. | Topical avermectin formulations and methods for elimination and prophylaxis of susceptible and treatment-resistant strains of head lice |
| US7953614B1 (en) | 2006-11-22 | 2011-05-31 | Dr Systems, Inc. | Smart placement rules |
| WO2010051348A1 (en) * | 2008-10-29 | 2010-05-06 | Topaz Pharmaceuticals Inc. | Preservative system for emulsion-based therapeutic topical formulations |
| CN102784166B (zh) * | 2012-08-01 | 2015-11-25 | 青岛绿曼生物工程有限公司 | 治疗家畜螨虫病的复方伊维菌素组合物及其制备方法 |
| CN102872066B (zh) | 2012-10-19 | 2014-07-02 | 厦门大学 | 伊维菌素及其衍生物的用途 |
| US9233118B2 (en) * | 2013-07-08 | 2016-01-12 | Galderma S.A. | Treatment of papulopustular rosacea with ivermectin |
| JP6448641B2 (ja) | 2013-11-29 | 2019-01-09 | ガルデルマ・ソシエテ・アノニム | アトピー性皮膚炎の治療及び/又は予防のためのアベルメクチンファミリー又はミルベマイシンファミリーの化合物 |
| WO2015144907A1 (fr) | 2014-03-28 | 2015-10-01 | Galderma Research & Development | Mousse chimique non rincée contenant du peroxyde de benzoyle |
| WO2016022066A1 (en) | 2014-08-04 | 2016-02-11 | Jerry Tan Eye Surgery Pte Ltd | Pharmaceutical compositions for demodex related blepharitis and eyelid crusting |
| CN104127334A (zh) * | 2014-08-19 | 2014-11-05 | 杨人源 | 一种杀菌除螨宠物香波 |
| WO2016079262A1 (fr) * | 2014-11-20 | 2016-05-26 | Galderma Sa | Compositions comprenant un compose de la famille des avermectines et un compose agoniste d'au moins un des recepteurs de l'acide retinoique pour le traitement de l'acne |
| FR3041541B1 (fr) * | 2015-09-29 | 2018-11-30 | Galderma Research & Development | Mousse chimique non rincee comprenant de l'ivermectine |
| FR3041539B1 (fr) | 2015-09-29 | 2018-10-26 | Galderma Research & Development | Composition nettoyante auto-moussante contenant du propionate de clobetasol, et son utilisation dans le traitement du psoriasis. |
| FR3041535B1 (fr) | 2015-09-29 | 2019-01-25 | Galderma Research & Development | Mousse chimique non rincee contenant du trifarotene, et son utilisation dans le traitement de l'ichtyose. |
| FR3041537B1 (fr) | 2015-09-29 | 2018-11-30 | Galderma Research & Development | Mousse chimique non rincee contenant de la brimonidine et son utilisation dans le traitement de la rosacee. |
| FR3041540B1 (fr) * | 2015-09-29 | 2018-10-26 | Galderma Research & Development | Composition nettoyante auto-moussante a rincer, contenant de l'ivermectine. |
| FR3041538B1 (fr) | 2015-09-29 | 2018-11-30 | Galderma Research & Development | Mousse chimique non rincee contenant du propionate de clobetasol, et son utilisation dans le traitement du psoriasis. |
| FR3041536B1 (fr) | 2015-09-29 | 2018-11-30 | Galderma Research & Development | Mousse chimique non rincee contenant du trifarotene, et son utilisation dans le traitement de l'acne. |
| EP3362097B1 (de) * | 2015-10-13 | 2021-07-14 | Galderma S.A. | Verfahren zur herstellung von stabiler emulsion mit einem oder mehreren avermectinen |
| US11160780B2 (en) * | 2016-09-30 | 2021-11-02 | Aurobindo Pharma Ltd. | Pharmaceutical composition of ivermectin and process for preparation thereof |
| TR201714097A2 (tr) * | 2017-09-22 | 2018-10-22 | Assos Ilac Kimya Gida Ueruenleri Ueretim Ve Ticaret Anonim Sirketi | İvermekti̇n topi̇k formülasyon |
| KR20250057155A (ko) | 2017-12-15 | 2025-04-28 | 타르서스 파마수티칼스, 아이엔씨. | 안검염을 치료하기 위한 이속사졸린 구충제 제제 및 방법 |
| WO2019136221A1 (en) * | 2018-01-05 | 2019-07-11 | Attillaps Holdings | Treating autoimmune disorders with chloroquine and/or hydroxychloroquine |
| WO2019152560A1 (en) * | 2018-01-31 | 2019-08-08 | Bio33 Degrees, Inc. | Compositions and methods for topical treatment of dermal and ocular conditions |
| CN108272750A (zh) * | 2018-04-25 | 2018-07-13 | 菏泽学院 | 一种治疗动物皮肤疥癣病的软膏剂及其制备方法 |
| WO2019241498A1 (en) | 2018-06-15 | 2019-12-19 | W. R. Grace & Co.-Conn | Defoamer active, manufacturing method thereof, and defoaming formuation |
| US12502377B2 (en) | 2019-04-04 | 2025-12-23 | Tarsus Pharmaceuticals, Inc. | Method of eradicating ticks that attach to humans using lotilaner formulations |
| WO2021247283A1 (en) * | 2020-06-04 | 2021-12-09 | Amcyte Pharma, Inc. | Delivery of aerosolized micromolar composition concentrations |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ197796A (en) | 1980-08-04 | 1984-11-09 | Merck & Co Inc | Stabilised aqueous formulations containing ivermectin |
| US5332577A (en) * | 1988-12-27 | 1994-07-26 | Dermamed | Transdermal administration to humans and animals |
| FR2725369B1 (fr) * | 1994-10-07 | 1997-01-03 | Oreal | Composition cosmetique ou dermatologique constituee d'une emulsion huile dans eau a base de globules huileux pourvus d'un enrobage cristal liquide lamellaire |
| US5656280A (en) | 1994-12-06 | 1997-08-12 | Helene Curtis, Inc. | Water-in-oil-in-water compositions |
| DE69636706T2 (de) | 1995-09-25 | 2007-10-11 | Ashmont Holdings Ltd., Takapuna | Makrocyclische lacton anthelmintika |
| FR2754452B1 (fr) | 1996-10-11 | 2003-02-14 | Oreal | Emulsion h/e a forte teneur en electrolytes et leur utilisation en dermo-cosmetique, notamment pour traiter les phenomenes d'irritation et/ou de peaux sensibles |
| US5952372A (en) * | 1998-09-17 | 1999-09-14 | Mcdaniel; William Robert | Method for treating rosacea using oral or topical ivermectin |
| US6521237B2 (en) * | 1998-11-12 | 2003-02-18 | Johnson & Johnson Consumer Companies, Inc. | Skin care composition |
| FR2787322B1 (fr) | 1998-12-18 | 2002-10-18 | Galderma Res & Dev | Emulsion huile-dans-eau comprenant un agent actif micronise et un systeme emulsionnant approprie |
| US6133310A (en) * | 1999-08-26 | 2000-10-17 | Parks; L. Dean | Method of treatment of rosacea |
| US6720001B2 (en) * | 1999-10-18 | 2004-04-13 | Lipocine, Inc. | Emulsion compositions for polyfunctional active ingredients |
| US6399651B1 (en) * | 2000-06-29 | 2002-06-04 | L. Dean Parks | Method of treating dermatoses using avermectin compound |
| US6399652B1 (en) * | 2000-06-29 | 2002-06-04 | L. Dean Parks | Method of treating acne vulgaris using avermectin compound |
| US6319945B1 (en) * | 2000-06-29 | 2001-11-20 | L. Dean Parks | Method of treatment of seborrheic dermatitis |
| EP1476121A4 (de) | 2002-02-08 | 2010-10-27 | Merck Sharp & Dohme | Topische ivermectin-zusammensetzung |
| EP1480633A2 (de) | 2002-03-04 | 2004-12-01 | Divergence, Inc. | Nematizide fettsäure- und fettsäureesterverwandte verbindungen |
| RU2350333C3 (ru) | 2003-04-24 | 2018-08-24 | Галдерма С.А. | Применение ивермектина для лечения дерматологических расстройств |
| FR2867684B1 (fr) | 2004-03-18 | 2006-05-05 | Galderma Sa | Gel creme contenant de l'ivermectine |
| DE602005020912D1 (de) | 2004-03-18 | 2010-06-10 | Galderma Sa | Ivermectin enthaltende creme |
-
2003
- 2003-04-24 FR FR0305048A patent/FR2854074B1/fr not_active Expired - Fee Related
-
2004
- 2004-04-22 CN CN201310731121.9A patent/CN103800353A/zh active Pending
- 2004-04-22 PT PT04728811T patent/PT1620113E/pt unknown
- 2004-04-22 KR KR1020127013727A patent/KR101291824B1/ko not_active Expired - Lifetime
- 2004-04-22 ES ES04728811T patent/ES2371945T3/es not_active Expired - Lifetime
- 2004-04-22 SI SI200431722T patent/SI1620113T1/sl unknown
- 2004-04-22 AR ARP040101354A patent/AR044050A1/es not_active Application Discontinuation
- 2004-04-22 CN CNA2004800109954A patent/CN1777433A/zh active Pending
- 2004-04-22 AT AT04728811T patent/ATE516037T1/de active
- 2004-04-22 DK DK04728811.3T patent/DK1620113T3/da active
-
2005
- 2005-09-13 ZA ZA200507346A patent/ZA200507346B/xx unknown
-
2013
- 2013-10-25 US US14/063,897 patent/US8815816B2/en not_active Expired - Lifetime
-
2014
- 2014-07-22 US US14/337,966 patent/US20140336139A1/en not_active Abandoned
-
2015
- 2015-07-06 US US14/792,250 patent/US20150306027A1/en not_active Abandoned
- 2015-07-06 US US14/792,201 patent/US20150306124A1/en not_active Abandoned
-
2017
- 2017-06-16 US US15/625,362 patent/US11033565B2/en not_active Expired - Fee Related
- 2017-06-16 US US15/625,239 patent/US20170281663A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20120062028A (ko) | 2012-06-13 |
| AR044050A1 (es) | 2005-08-24 |
| SI1620113T1 (sl) | 2011-10-28 |
| FR2854074B1 (fr) | 2007-11-23 |
| US8815816B2 (en) | 2014-08-26 |
| US20150306124A1 (en) | 2015-10-29 |
| US11033565B2 (en) | 2021-06-15 |
| FR2854074A1 (fr) | 2004-10-29 |
| KR101291824B1 (ko) | 2013-07-31 |
| ZA200507346B (en) | 2006-08-30 |
| CN1777433A (zh) | 2006-05-24 |
| CN103800353A (zh) | 2014-05-21 |
| PT1620113E (pt) | 2011-09-12 |
| US20170281664A1 (en) | 2017-10-05 |
| US20140051653A1 (en) | 2014-02-20 |
| US20140336139A1 (en) | 2014-11-13 |
| DK1620113T3 (da) | 2011-09-12 |
| ES2371945T3 (es) | 2012-01-11 |
| US20170281663A1 (en) | 2017-10-05 |
| US20150306027A1 (en) | 2015-10-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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