CA2478338A1 - Combination therapy for treating, preventing or managing proliferative disorders and cancers - Google Patents
Combination therapy for treating, preventing or managing proliferative disorders and cancers Download PDFInfo
- Publication number
- CA2478338A1 CA2478338A1 CA002478338A CA2478338A CA2478338A1 CA 2478338 A1 CA2478338 A1 CA 2478338A1 CA 002478338 A CA002478338 A CA 002478338A CA 2478338 A CA2478338 A CA 2478338A CA 2478338 A1 CA2478338 A1 CA 2478338A1
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- chz
- cancer
- jnk
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Landscapes
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| US10/384,440 | 2003-03-07 | ||
| US10/384,440 US7351729B2 (en) | 2002-03-08 | 2003-03-07 | JNK inhibitors for use in combination therapy for treating or managing proliferative disorders and cancers |
| PCT/US2003/006894 WO2003075917A1 (en) | 2002-03-08 | 2003-03-07 | Combination therapy for treating, preventing or managing proliferative disorders and cancers |
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| US8183339B1 (en) | 1999-10-12 | 2012-05-22 | Xigen S.A. | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
| US20040082509A1 (en) | 1999-10-12 | 2004-04-29 | Christophe Bonny | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
| MXPA04009997A (es) * | 2002-04-12 | 2004-12-13 | Celgene Corp | Modulacion de la diferenciacion de celulas madre y progenitoras, ensayos y usos de las mismas. |
| US7393862B2 (en) | 2002-05-17 | 2008-07-01 | Celgene Corporation | Method using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias |
| USRE48890E1 (en) | 2002-05-17 | 2022-01-11 | Celgene Corporation | Methods for treating multiple myeloma with 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione after stem cell transplantation |
| US7968569B2 (en) * | 2002-05-17 | 2011-06-28 | Celgene Corporation | Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione |
| JP2005528105A (ja) * | 2002-05-30 | 2005-09-22 | セルジーン・コーポレーション | 細胞分化をモジュレートするため、並びに骨髄増殖性疾患及び骨髄異形成症候群を治療するためのjnk又はmkk阻害剤の使用方法 |
| US7189740B2 (en) * | 2002-10-15 | 2007-03-13 | Celgene Corporation | Methods of using 3-(4-amino-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myelodysplastic syndromes |
| US20040087642A1 (en) * | 2002-10-24 | 2004-05-06 | Zeldis Jerome B. | Methods of using and compositions comprising a JNK inhibitor for the treatment, prevention, management and/or modification of pain |
| US8034831B2 (en) | 2002-11-06 | 2011-10-11 | Celgene Corporation | Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies |
| CA2505003A1 (en) * | 2002-11-06 | 2004-05-27 | Celgene Corporation | Methods of using and compositions comprising selective cytokine inhibitory drugs for the treatment and management of myeloproliferative diseases |
| US7563810B2 (en) * | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
| US20050267144A1 (en) * | 2003-01-06 | 2005-12-01 | Eugene Mandrea | Methods of stimulating immune response in virally infected individuals |
| US7893083B2 (en) * | 2003-01-06 | 2011-02-22 | Eugene Mandrea | Method of treating genital herpes |
| US20060183767A1 (en) * | 2003-01-06 | 2006-08-17 | Eugene Mandrea | Methods of stimulating immune response in certain individuals |
| US20070020234A1 (en) * | 2003-07-07 | 2007-01-25 | Vande Woude George F | Inhibition of tumor angiogenesis by combination of thrombospondin-1 and inhibitors of vascular endothelial growth factor |
| WO2005046594A2 (en) * | 2003-11-06 | 2005-05-26 | Celgene Corporation | Methods of using and compositions comprising a jnk inhibitor for the treatment and management of asbestos-related diseases and disorders |
| EP1756139A4 (en) * | 2004-03-12 | 2009-07-29 | Entremed Inc | ANTI-ANGIOGENIC AGENTS |
| US20100009928A1 (en) | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and taxanes and methods of use thereof |
| US20100173864A1 (en) | 2004-03-29 | 2010-07-08 | Cheng Jin Q | Compositions including triciribine and one or more platinum compounds and methods of use thereof |
| US20110008327A1 (en) | 2004-03-29 | 2011-01-13 | Cheng Jin Q | Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof |
| US20100009929A1 (en) | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof |
| US20100028339A1 (en) | 2004-03-29 | 2010-02-04 | Cheng Jin Q | Compositions including triciribine and trastuzumab and methods of use thereof |
| HUE032657T2 (en) | 2004-03-29 | 2017-10-30 | Univ South Florida | Effective treatment of tumors and cancer with triciribin phosphate |
| MXPA06012701A (es) * | 2004-05-05 | 2007-02-14 | Celgene Corp | Metodo de utilizacion y composiciones que comprenden farmacos inhibidores de citocina selectivos para el tratamiento y manejo de enfermedades mieloproliferativas. |
| MX2007001132A (es) * | 2004-07-27 | 2007-03-15 | Novartis Ag | Inhibidores de hsp90. |
| EP1676574A3 (en) | 2004-12-30 | 2006-07-26 | Johnson & Johnson Vision Care, Inc. | Methods for promoting survival of transplanted tissues and cells |
| US20060204474A1 (en) * | 2005-02-25 | 2006-09-14 | Coroneo Minas T | Treatment of epithelial layer lesions |
| BRPI0613042A2 (pt) * | 2005-07-15 | 2010-12-14 | Serono Lab | inibidores de jnk para o tratamento de endometriose |
| KR20080044836A (ko) | 2005-07-15 | 2008-05-21 | 라보라뚜와르 세로노 에스. 에이. | 자궁내막증 치료용 jnk 억제제 |
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| WO2007031098A1 (en) | 2005-09-12 | 2007-03-22 | Xigen S.A. | Cell-permeable peptide inhibitors of the jnk signal transduction pathway |
| CN1870631B (zh) * | 2005-11-11 | 2010-04-14 | 华为技术有限公司 | 媒体网关的门控方法 |
| US20070185069A1 (en) * | 2005-11-14 | 2007-08-09 | Plum Stacy M | Anti-angiogenic activity of 2-methoxyestradiol in combination with anti-cancer agents |
| US20090221488A1 (en) * | 2005-12-08 | 2009-09-03 | Wood Kenneth W | Certain Compositions and Methods of Treatment |
| CU23511B6 (es) | 2006-02-28 | 2010-04-13 | Biorec B V | Combinación farmacéutica para el tratamiento y/o quimiosensibilización de tumores refractarios a drogas anticancerígenas |
| EP2001482B1 (en) * | 2006-03-20 | 2016-08-24 | CASI Pharmaceuticals, Inc. | Disease modifying anti-arthritic activity of 2-methoxyestradiol |
| EP2338488A1 (en) * | 2006-05-26 | 2011-06-29 | Bayer HealthCare, LLC | Drug combinations with substituted diaryl ureas for the treatment of cancer |
| US20080070855A1 (en) * | 2006-09-20 | 2008-03-20 | James Pitzer Gills | Treatment with anti-VEGF agents to prevent postoperative inflammation and angiogenesis in normal and diseased eyes |
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| EP2047858A1 (en) * | 2007-10-10 | 2009-04-15 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Combination products for treating cancer |
| CA2705859A1 (en) * | 2007-10-15 | 2009-04-23 | John P. Stokes | Convergent well irradiating plaque for choroidal melanoma |
| TWI468417B (zh) | 2007-11-30 | 2015-01-11 | Genentech Inc | 抗-vegf抗體 |
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| FR2805810B1 (fr) | 2000-03-03 | 2002-04-26 | Aventis Pharma Sa | Compositions pharmaceutiques contenant des derives de 3- amino-azetidine, les nouveaux derives et leur preparation |
| FR2805817B1 (fr) | 2000-03-03 | 2002-04-26 | Aventis Pharma Sa | Compositions pharmaceutiques contenant des derives d'azetidine, les nouveaux derives d'azetidine et leur preparation |
| FR2805818B1 (fr) | 2000-03-03 | 2002-04-26 | Aventis Pharma Sa | Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant |
| DE60124685T2 (de) | 2000-03-23 | 2007-03-29 | Solvay Pharmaceuticals B.V. | 4,5-dihydro-1h-pyrazolderivate mit cb1-antagonistischer aktivität |
| DE10015866A1 (de) | 2000-03-30 | 2001-10-11 | Bayer Ag | Aryl- und Heteroarylsulfonate |
| US6448288B1 (en) | 2000-05-17 | 2002-09-10 | University Of Massachusetts | Cannabinoid drugs |
| AU2001264930A1 (en) | 2000-05-23 | 2001-12-03 | The Regents Of The University Of California | A novel treatment for cough |
| JP2003535062A (ja) | 2000-06-01 | 2003-11-25 | メルク エンド カムパニー インコーポレーテッド | Jnk阻害剤としての(二置換フェニル)ピリミジニルイミダゾール誘導体の使用 |
| CN1203070C (zh) | 2000-06-15 | 2005-05-25 | 先灵公司 | 凝血酶受体拮抗药 |
| IL136839A (en) | 2000-06-16 | 2006-12-10 | Yissum Res Dev Co | Pharmaceutical compositions comprising cannabidiol derivatives, and processes for the preparation of same |
| CA2411585A1 (en) | 2000-06-22 | 2001-12-27 | Pharmos Corporation | Novel non-psychotropic cannabinoids |
| US6897231B2 (en) * | 2000-07-31 | 2005-05-24 | Signal Pharmaceuticals, Inc. | Indazole derivatives as JNK inhibitors and compositions and methods related thereto |
| IL154082A0 (en) | 2000-08-01 | 2003-07-31 | Ono Pharmaceutical Co | 3,4-dihydroisoquinoline derivative compounds and drugs containing these compounds as the active ingredient |
| DE10042663A1 (de) | 2000-08-31 | 2002-03-14 | Deutsche Telekom Ag | Eletronenspektrometer |
| AU2001288325A1 (en) | 2000-09-22 | 2002-04-02 | Eli Lilly And Company | Pharmaceutical compounds useful as modulators of endocannabinoid-mediated response |
| DE10047486A1 (de) | 2000-09-26 | 2002-04-11 | Bayer Ag | Phenoxyphenyl Alkansulfonate |
| FR2814678B1 (fr) | 2000-10-04 | 2002-12-20 | Aventis Pharma Sa | Association d'un antagoniste du recepteur cb1 et de sibutramine, les compositions pharmaceutiques les contenant et leur utilisation pour la traitement de l'obesite |
| AUPR118000A0 (en) | 2000-11-02 | 2000-11-23 | Amrad Operations Pty. Limited | Therapeutic molecules and methods |
| FR2816938B1 (fr) | 2000-11-22 | 2003-01-03 | Sanofi Synthelabo | Derives de 3-aroylindole, leur procede de preparation et les compositions pharmaceutiques en contenant |
| GB0028702D0 (en) | 2000-11-24 | 2001-01-10 | Novartis Ag | Organic compounds |
| US7129242B2 (en) | 2000-12-06 | 2006-10-31 | Signal Pharmaceuticals, Llc | Anilinopyrimidine derivatives as JNK pathway inhibitors and compositions and methods related thereto |
| US20020077322A1 (en) | 2000-12-15 | 2002-06-20 | Ayoub George S. | Protection of neurons against glutamate-induced damage in glaucoma and other conditions |
| CA2433158C (en) | 2000-12-28 | 2011-05-10 | Shionogi & Co., Ltd. | Pyridone derivatives having a binding activity to the cannabinoid type 2 receptor |
| JP2004532185A (ja) | 2001-01-26 | 2004-10-21 | ユニバーシティ オブ コネチカット | 新規なカンナビミメティックリガンド |
| JP2005503998A (ja) | 2001-01-29 | 2005-02-10 | ユニバーシティ オブ コネチカット | 受容体選択性のカンナビミメティックアミノアルキルインドール |
| US7507767B2 (en) | 2001-02-08 | 2009-03-24 | Schering Corporation | Cannabinoid receptor ligands |
| US6987184B2 (en) | 2001-02-15 | 2006-01-17 | Signal Pharmaceuticals, Llc | Isothiazoloanthrones, isoxazoloanthrones, isoindolanthrones and derivatives thereof as JNK inhibitors and compositions and methods related |
| GB0104268D0 (en) | 2001-02-21 | 2001-04-11 | Unilever Plc | Antiperspirant or deodorant compositions |
| US6916806B2 (en) | 2001-03-08 | 2005-07-12 | Shionogi & Co., Ltd. | Medicinal composition containing 1,3-thiazine derivative |
| ATE447403T1 (de) | 2001-04-06 | 2009-11-15 | Univ Illinois | Cannabinoiden zur behandlung von während des schlafens auftretenden atmungsstörungen |
| SE0101387D0 (sv) | 2001-04-20 | 2001-04-20 | Astrazeneca Ab | Novel compounds |
| CA2477842A1 (en) | 2001-04-24 | 2002-10-31 | President And Fellows Of Harvard College | Inhibition of jun kinase |
| TW200306819A (en) * | 2002-01-25 | 2003-12-01 | Vertex Pharma | Indazole compounds useful as protein kinase inhibitors |
| US7498171B2 (en) * | 2002-04-12 | 2009-03-03 | Anthrogenesis Corporation | Modulation of stem and progenitor cell differentiation, assays, and uses thereof |
| JP2005528105A (ja) * | 2002-05-30 | 2005-09-22 | セルジーン・コーポレーション | 細胞分化をモジュレートするため、並びに骨髄増殖性疾患及び骨髄異形成症候群を治療するためのjnk又はmkk阻害剤の使用方法 |
-
2003
- 2003-03-07 EP EP03713937A patent/EP1487436A4/en not_active Withdrawn
- 2003-03-07 NZ NZ535349A patent/NZ535349A/en unknown
- 2003-03-07 JP JP2003574192A patent/JP2005533748A/ja active Pending
- 2003-03-07 US US10/384,440 patent/US7351729B2/en not_active Expired - Fee Related
- 2003-03-07 CA CA002478338A patent/CA2478338A1/en not_active Abandoned
- 2003-03-07 AU AU2003217961A patent/AU2003217961B2/en not_active Ceased
- 2003-03-07 WO PCT/US2003/006894 patent/WO2003075917A1/en not_active Ceased
-
2007
- 2007-02-09 US US11/704,665 patent/US20070149571A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1487436A1 (en) | 2004-12-22 |
| AU2003217961A1 (en) | 2003-09-22 |
| JP2005533748A (ja) | 2005-11-10 |
| US7351729B2 (en) | 2008-04-01 |
| AU2003217961B2 (en) | 2008-02-28 |
| US20070149571A1 (en) | 2007-06-28 |
| US20040067953A1 (en) | 2004-04-08 |
| NZ535349A (en) | 2007-01-26 |
| WO2003075917A1 (en) | 2003-09-18 |
| EP1487436A4 (en) | 2009-06-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued | ||
| FZDE | Discontinued |
Effective date: 20110127 |