AU3786899A - Crystallizable jnk complexes - Google Patents

Crystallizable jnk complexes

Info

Publication number
AU3786899A
AU3786899A AU37868/99A AU3786899A AU3786899A AU 3786899 A AU3786899 A AU 3786899A AU 37868/99 A AU37868/99 A AU 37868/99A AU 3786899 A AU3786899 A AU 3786899A AU 3786899 A AU3786899 A AU 3786899A
Authority
AU
Australia
Prior art keywords
jnk
crystallizable
complexes
jnk complexes
crystallizable jnk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU37868/99A
Inventor
Paul R. Caron
Edward Fox
Yong Gu
William Markland
Michael S. Su
Keith P Wilson
Xiaoling Xie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vertex Pharmaceuticals Inc
Original Assignee
Vertex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharmaceuticals Inc filed Critical Vertex Pharmaceuticals Inc
Publication of AU3786899A publication Critical patent/AU3786899A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
AU37868/99A 1998-05-04 1999-05-04 Crystallizable jnk complexes Abandoned AU3786899A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8405698P 1998-05-04 1998-05-04
US60084056 1998-05-04
PCT/US1999/009824 WO1999057253A2 (en) 1998-05-04 1999-05-04 Crystallizable jnk complexes

Publications (1)

Publication Number Publication Date
AU3786899A true AU3786899A (en) 1999-11-23

Family

ID=22182612

Family Applications (1)

Application Number Title Priority Date Filing Date
AU37868/99A Abandoned AU3786899A (en) 1998-05-04 1999-05-04 Crystallizable jnk complexes

Country Status (4)

Country Link
EP (1) EP1076692A2 (en)
JP (1) JP2002513562A (en)
AU (1) AU3786899A (en)
WO (1) WO1999057253A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7301021B2 (en) 1997-07-02 2007-11-27 Smithkline Beecham Corporation Substituted imidazole compounds
US7383135B1 (en) * 1998-05-04 2008-06-03 Vertex Pharmaceuticals Incorporated Methods of designing inhibitors for JNK kinases
EP1235814B1 (en) 1999-11-23 2004-11-03 Smithkline Beecham Corporation 3,4-DIHYDRO-(1H)QUINAZOLIN-2-ONE COMPOUNDS AS CSBP/p38 KINASE INHIBITORS
US6638908B1 (en) 2000-08-09 2003-10-28 Yale University Crystals of the large ribosomal subunit
US6987184B2 (en) 2001-02-15 2006-01-17 Signal Pharmaceuticals, Llc Isothiazoloanthrones, isoxazoloanthrones, isoindolanthrones and derivatives thereof as JNK inhibitors and compositions and methods related
WO2003060102A2 (en) * 2002-01-11 2003-07-24 Vertex Pharmaceuticals Incorporated Crystal structures of jnk-inhibitor complexes and binding pockets thereof
NZ535349A (en) 2002-03-08 2007-01-26 Signal Pharm Inc JNK inhibitors with chemotherapeutic agents in a combination therapy for treating or preventing cancer and other proliferative disorders in refractory patients in particular
ES2456702T3 (en) * 2003-05-09 2014-04-23 Boehringer Ingelheim International Gmbh Hepatitis C virus NS5B polymerase inhibitor binding pocket

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5978740A (en) * 1995-08-09 1999-11-02 Vertex Pharmaceuticals Incorporated Molecules comprising a calcineurin-like binding pocket and encoded data storage medium capable of graphically displaying them

Also Published As

Publication number Publication date
WO1999057253A3 (en) 1999-12-16
JP2002513562A (en) 2002-05-14
WO1999057253A2 (en) 1999-11-11
EP1076692A2 (en) 2001-02-21

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase