CA2466657A1 - Systeme de liberation prolongee de medicaments solubles - Google Patents

Systeme de liberation prolongee de medicaments solubles Download PDF

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Publication number
CA2466657A1
CA2466657A1 CA002466657A CA2466657A CA2466657A1 CA 2466657 A1 CA2466657 A1 CA 2466657A1 CA 002466657 A CA002466657 A CA 002466657A CA 2466657 A CA2466657 A CA 2466657A CA 2466657 A1 CA2466657 A1 CA 2466657A1
Authority
CA
Canada
Prior art keywords
pharmaceutical formulation
sustained release
oral sustained
release pharmaceutical
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002466657A
Other languages
English (en)
Other versions
CA2466657C (fr
Inventor
Victoria Rogers
Philippe J. M. Dor
Joseph A. Fix
Hiroyuki Kojima
Kazuhiro Sako
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2466657A1 publication Critical patent/CA2466657A1/fr
Application granted granted Critical
Publication of CA2466657C publication Critical patent/CA2466657C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating

Abstract

L'invention se rapporte à de nouvelles préparations orales à libération prolongée afin d'administrer un agent actif (par exemple un médicament), notamment un médicament fortement hydrosoluble. Plus précisément, cette invention porte sur de nouvelles préparations contenant un médicament à formation de micelles présentant une charge et au moins un polymère possédant une charge opposée. L'invention concerne des procédés d'utilisation des nouvelles préparations.
CA2466657A 2001-11-13 2002-11-12 Systeme de liberation prolongee de medicaments solubles Expired - Fee Related CA2466657C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US787701A 2001-11-13 2001-11-13
US10/007,877 2001-11-13
PCT/US2002/036681 WO2003041656A2 (fr) 2001-11-13 2002-11-12 Systeme de liberation prolongee de medicaments solubles

Publications (2)

Publication Number Publication Date
CA2466657A1 true CA2466657A1 (fr) 2003-05-22
CA2466657C CA2466657C (fr) 2011-02-01

Family

ID=21728577

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2466657A Expired - Fee Related CA2466657C (fr) 2001-11-13 2002-11-12 Systeme de liberation prolongee de medicaments solubles

Country Status (10)

Country Link
EP (1) EP1443901A4 (fr)
JP (2) JP4882200B2 (fr)
KR (2) KR101016619B1 (fr)
CN (1) CN100534531C (fr)
AU (1) AU2002348279C1 (fr)
CA (1) CA2466657C (fr)
MX (1) MXPA04004544A (fr)
PL (1) PL374280A1 (fr)
RU (1) RU2322263C2 (fr)
WO (1) WO2003041656A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050042289A1 (en) * 2003-04-29 2005-02-24 Yamanouchi Pharma Technologies, Inc. Tablets and methods for modified release of hydrophylic and other active agents
JP4822092B2 (ja) * 2003-09-01 2011-11-24 大正製薬株式会社 Ｗ／ｏ／ｗ型複合エマルション
US20060210625A1 (en) * 2003-11-04 2006-09-21 Shire Laboratories, Inc. Sustained release of positively charged pharmacologically active molecules from a matrix containing polymers with polarized oxygen atoms
US8197846B2 (en) * 2003-11-10 2012-06-12 Astellas Pharma Inc. Sustained release pharmaceutical composition
KR100638041B1 (ko) * 2003-12-24 2006-10-23 주식회사 삼양사 수용성 약물의 경구투여용 나노입자 조성물 및 그의제조방법
EP2412366A4 (fr) * 2009-03-25 2013-08-07 Lintec Corp Préparation solide
KR101319420B1 (ko) * 2011-03-18 2013-10-17 한남대학교 산학협력단 서방형 방출이 가능한 수용성 양이온 약물 전달 시스템
EP2696853B1 (fr) * 2011-04-11 2019-10-23 Council of Scientific & Industrial Research Dissociation de nano-containers induite en surface
CN102977413B (zh) * 2011-09-07 2015-05-13 江南大学 聚合物复合制备胶束的一种新方法
CN103083222B (zh) * 2011-10-28 2015-08-19 江南大学 一锅法制备三组分聚合物胶束
JP6041823B2 (ja) 2013-03-16 2016-12-14 ファイザー・インク トファシチニブの経口持続放出剤形
WO2022038409A1 (fr) * 2020-08-19 2022-02-24 주식회사 모든바이오 Nanoparticules comprenant de la glycyrrhizine et un médicament soluble dans l'eau, composition pharmaceutique les contenant, et leurs procédés de préparation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE32806B1 (en) * 1968-05-21 1973-12-12 American Home Prod Sustained release drug composition
JPS6410466A (en) * 1987-07-01 1989-01-13 Brother Ind Ltd Data recording and reproducing method for magnetic disk
US5219563A (en) * 1988-05-11 1993-06-15 Glaxo Group Limited Drug adsorbates
PL175026B1 (pl) * 1992-09-18 1998-10-30 Yamanouchi Pharma Co Ltd Preparat typu hydrożelu o przedłużonym działaniu
US5788959A (en) * 1995-04-24 1998-08-04 University Of Maryland, Baltimore County Drug delivery device and method for employing the same
CA2228610C (fr) * 1995-08-17 2008-06-03 Heidi Rolfes Produits a liberation controlee
IT1297461B1 (it) * 1997-10-29 1999-12-17 Ciocca Maurizio Preparazione di compresse a rilascio controllato a base di complessi tra carragenano e farmaci basici solubili
SK285478B6 (sk) * 1998-09-14 2007-02-01 Ranbaxy Laboratories Limited Jednodenná formulácia na orálne podanie na kontrolované uvoľňovanie ciprofloxacínu
US6287599B1 (en) * 2000-12-20 2001-09-11 Shire Laboratories, Inc. Sustained release pharmaceutical dosage forms with minimized pH dependent dissolution profiles
AR034517A1 (es) * 2001-06-21 2004-02-25 Astrazeneca Ab Formulacion farmaceutica

Also Published As

Publication number Publication date
EP1443901A2 (fr) 2004-08-11
CN100534531C (zh) 2009-09-02
JP2005508995A (ja) 2005-04-07
KR20050044424A (ko) 2005-05-12
KR20100123779A (ko) 2010-11-24
JP4882200B2 (ja) 2012-02-22
KR101132969B1 (ko) 2012-04-09
AU2002348279B2 (en) 2008-01-24
KR101016619B1 (ko) 2011-02-23
CA2466657C (fr) 2011-02-01
JP2011068700A (ja) 2011-04-07
CN1612726A (zh) 2005-05-04
EP1443901A4 (fr) 2010-06-16
WO2003041656A2 (fr) 2003-05-22
MXPA04004544A (es) 2005-03-31
RU2004117848A (ru) 2005-05-27
RU2322263C2 (ru) 2008-04-20
JP4894958B2 (ja) 2012-03-14
PL374280A1 (en) 2005-10-03
WO2003041656A3 (fr) 2003-10-23
AU2002348279C1 (en) 2008-09-04

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Effective date: 20151112