CA2464086C - Post-modification of a porous support - Google Patents

Post-modification of a porous support Download PDF

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Publication number
CA2464086C
CA2464086C CA2464086A CA2464086A CA2464086C CA 2464086 C CA2464086 C CA 2464086C CA 2464086 A CA2464086 A CA 2464086A CA 2464086 A CA2464086 A CA 2464086A CA 2464086 C CA2464086 C CA 2464086C
Authority
CA
Canada
Prior art keywords
support
post
polymeric support
macroporous
grafting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2464086A
Other languages
English (en)
French (fr)
Other versions
CA2464086A1 (en
Inventor
Henrik Ihre
Anders Larsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Global Life Sciences Solutions USA LLC
Original Assignee
GE Healthcare Bio Sciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Bio Sciences Corp filed Critical GE Healthcare Bio Sciences Corp
Publication of CA2464086A1 publication Critical patent/CA2464086A1/en
Application granted granted Critical
Publication of CA2464086C publication Critical patent/CA2464086C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206Organic carriers, supports or substrates
    • B01J20/3208Polymeric carriers, supports or substrates
    • B01J20/321Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32Bonded phase chromatography
    • B01D15/325Reversed phase
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361Ion-exchange
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26Synthetic macromolecular compounds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26Synthetic macromolecular compounds
    • B01J20/264Synthetic macromolecular compounds derived from different types of monomers, e.g. linear or branched copolymers, block copolymers, graft copolymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26Synthetic macromolecular compounds
    • B01J20/265Synthetic macromolecular compounds modified or post-treated polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/287Non-polar phases; Reversed phases
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268Macromolecular compounds
    • B01J20/327Polymers obtained by reactions involving only carbon to carbon unsaturated bonds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268Macromolecular compounds
    • B01J20/3278Polymers being grafted on the carrier
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F251/00Macromolecular compounds obtained by polymerising monomers on to polysaccharides or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F257/00Macromolecular compounds obtained by polymerising monomers on to polymers of aromatic monomers as defined in group C08F12/00
    • C08F257/02Macromolecular compounds obtained by polymerising monomers on to polymers of aromatic monomers as defined in group C08F12/00 on to polymers of styrene or alkyl-substituted styrenes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F265/00Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
    • C08F265/04Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of esters
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/36After-treatment
    • C08J9/40Impregnation
    • C08J9/405Impregnation with polymerisable compounds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/50Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54Sorbents specially adapted for analytical or investigative chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Graft Or Block Polymers (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
CA2464086A 2001-11-26 2002-11-25 Post-modification of a porous support Expired - Fee Related CA2464086C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0103968-4 2001-11-26
SE0103968 2001-11-26
PCT/SE2002/002159 WO2003046063A1 (en) 2001-11-26 2002-11-25 Post-modification of a porous support

Publications (2)

Publication Number Publication Date
CA2464086A1 CA2464086A1 (en) 2003-06-05
CA2464086C true CA2464086C (en) 2011-01-18

Family

ID=20286116

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2464086A Expired - Fee Related CA2464086C (en) 2001-11-26 2002-11-25 Post-modification of a porous support

Country Status (6)

Country Link
US (1) US7060187B2 (enExample)
EP (1) EP1448684A1 (enExample)
JP (1) JP2005510609A (enExample)
AU (1) AU2002353728B2 (enExample)
CA (1) CA2464086C (enExample)
WO (1) WO2003046063A1 (enExample)

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US7060187B2 (en) * 2001-11-26 2006-06-13 Ge Healthcare Bio-Sciences Ab Post-modification of a porous support
WO2003046027A1 (en) * 2001-11-26 2003-06-05 Amersham Biosciences Ab Post-modification of a porous support
SE0201623D0 (sv) 2002-05-30 2002-05-30 Amersham Biosciences Ab Macroporous cross-linked polymer particles
SE0302509D0 (sv) * 2003-09-19 2003-09-19 Amersham Biosciences Ab Matrix for separation of polyethers and method of separation
SE0303532D0 (sv) * 2003-12-23 2003-12-23 Amersham Biosciences Ab Purification of immunoglobulins
SE0401665D0 (sv) 2004-06-24 2004-06-24 Amersham Biosciences Ab Purification of immunoglobulins
US20070055013A1 (en) * 2005-02-21 2007-03-08 Noriho Kamiya Substrate and method of immobilizing protein
FR2884253B1 (fr) * 2005-04-08 2007-06-22 Univ Lille Sciences Tech Materiaux monolithiques fonctionnalisables
US8137559B2 (en) 2007-02-09 2012-03-20 Ge Healthcare Bio-Sciences Ab Liquid clarification
US9044740B2 (en) 2007-03-30 2015-06-02 Ge Healthcare Bio-Sciences Ab Purification of immunoglobulins
JP2011016036A (ja) * 2007-11-26 2011-01-27 Asahi Kasei Chemicals Corp タンパク吸着材料およびその製造方法
ES2482110T3 (es) * 2008-05-30 2014-08-01 Merck Patent Gmbh Polimerización por injerto iniciada por ce(iv) en polímeros que no contienen grupos hidroxilo
BRPI0914610B1 (pt) 2008-06-26 2018-03-06 3M Innovative Properties Company Suporte sólido com uma cadeia enxertada
WO2010126087A1 (ja) * 2009-04-30 2010-11-04 ダイセル化学工業株式会社 光学異性体用分離剤
JP5474881B2 (ja) * 2010-07-28 2014-04-16 ローム アンド ハース カンパニー 向上したクロマトグラフィー媒体の製造方法および使用方法
JP5460651B2 (ja) * 2010-07-28 2014-04-02 ローム アンド ハース カンパニー クロマトグラフィー媒体性能を向上させるグラフト化方法
JP5631271B2 (ja) * 2010-07-28 2014-11-26 ローム アンド ハース カンパニーRohm And Haas Company 改良されたクロマトグラフィー媒体の製造方法および使用方法
KR20130028939A (ko) * 2010-07-29 2013-03-20 이엠디 밀리포어 코포레이션 크로마토그래피 매질 성능을 개선하기 위한 그라프팅 방법
EP2915840A4 (en) * 2012-10-30 2016-08-10 Kuraray Co POROUS PFROPOPOPOLYMER PARTICLES, METHOD FOR THE MANUFACTURE THEREOF AND ADSORBING MATERIAL THEREWITH
EP3055060A4 (en) * 2013-10-10 2017-05-24 GE Healthcare BioProcess R&D AB Method for production of a chromatography material
JP6192487B2 (ja) * 2013-10-30 2017-09-06 株式会社クラレ 多孔質グラフト共重合体粒子、その製造方法及びそれを用いた吸着材
EP3248677B1 (en) * 2015-01-19 2020-11-11 Hitachi Chemical Company, Ltd. Separation material
JP6746914B2 (ja) * 2016-01-07 2020-08-26 日立化成株式会社 分離材及びカラム
JP6939021B2 (ja) * 2017-03-30 2021-09-22 昭和電工マテリアルズ株式会社 分離材及びカラム
CN107446086B (zh) * 2017-09-06 2020-05-08 福建出入境检验检疫局检验检疫技术中心 一种六价铬印迹材料的制备方法

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Also Published As

Publication number Publication date
AU2002353728B2 (en) 2008-04-10
US20050065282A1 (en) 2005-03-24
AU2002353728A1 (en) 2003-06-10
CA2464086A1 (en) 2003-06-05
WO2003046063A1 (en) 2003-06-05
US7060187B2 (en) 2006-06-13
EP1448684A1 (en) 2004-08-25
JP2005510609A (ja) 2005-04-21

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