JP2005510609A - 多孔性支持体の後修飾 - Google Patents

多孔性支持体の後修飾 Download PDF

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Publication number
JP2005510609A
JP2005510609A JP2003547506A JP2003547506A JP2005510609A JP 2005510609 A JP2005510609 A JP 2005510609A JP 2003547506 A JP2003547506 A JP 2003547506A JP 2003547506 A JP2003547506 A JP 2003547506A JP 2005510609 A JP2005510609 A JP 2005510609A
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JP
Japan
Prior art keywords
post
support
polymeric support
macroporous
grafting
Prior art date
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Ceased
Application number
JP2003547506A
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English (en)
Japanese (ja)
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JP2005510609A5 (enExample
Inventor
ヘンリク・イーレ
アンデッシュ・ラーション
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Cytiva Sweden AB
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Amersham Bioscience AB
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Application filed by Amersham Bioscience AB filed Critical Amersham Bioscience AB
Publication of JP2005510609A publication Critical patent/JP2005510609A/ja
Publication of JP2005510609A5 publication Critical patent/JP2005510609A5/ja
Ceased legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/264—Synthetic macromolecular compounds derived from different types of monomers, e.g. linear or branched copolymers, block copolymers, graft copolymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/287—Non-polar phases; Reversed phases
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/327—Polymers obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3278—Polymers being grafted on the carrier
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F251/00—Macromolecular compounds obtained by polymerising monomers on to polysaccharides or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F257/00—Macromolecular compounds obtained by polymerising monomers on to polymers of aromatic monomers as defined in group C08F12/00
    • C08F257/02—Macromolecular compounds obtained by polymerising monomers on to polymers of aromatic monomers as defined in group C08F12/00 on to polymers of styrene or alkyl-substituted styrenes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F265/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
    • C08F265/04—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/36—After-treatment
    • C08J9/40—Impregnation
    • C08J9/405—Impregnation with polymerisable compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Graft Or Block Polymers (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
JP2003547506A 2001-11-26 2002-11-25 多孔性支持体の後修飾 Ceased JP2005510609A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0103968 2001-11-26
PCT/SE2002/002159 WO2003046063A1 (en) 2001-11-26 2002-11-25 Post-modification of a porous support

Publications (2)

Publication Number Publication Date
JP2005510609A true JP2005510609A (ja) 2005-04-21
JP2005510609A5 JP2005510609A5 (enExample) 2008-10-09

Family

ID=20286116

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003547506A Ceased JP2005510609A (ja) 2001-11-26 2002-11-25 多孔性支持体の後修飾

Country Status (6)

Country Link
US (1) US7060187B2 (enExample)
EP (1) EP1448684A1 (enExample)
JP (1) JP2005510609A (enExample)
AU (1) AU2002353728B2 (enExample)
CA (1) CA2464086C (enExample)
WO (1) WO2003046063A1 (enExample)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012032391A (ja) * 2010-07-28 2012-02-16 Rohm & Haas Co 改良されたクロマトグラフィー媒体の製造方法および使用方法
JP2012032390A (ja) * 2010-07-28 2012-02-16 Rohm & Haas Co 向上したクロマトグラフィー媒体の製造方法および使用方法
JP2012032392A (ja) * 2010-07-28 2012-02-16 Rohm & Haas Co クロマトグラフィー媒体性能を向上させるグラフト化方法
JP2013532829A (ja) * 2010-07-29 2013-08-19 イー・エム・デイー・ミリポア・コーポレイシヨン クロマトグラフィーの媒介性能を改善するためのグラフト法
WO2014069474A1 (ja) * 2012-10-30 2014-05-08 株式会社クラレ 多孔質グラフト共重合体粒子、その製造方法及びそれを用いた吸着材
JP2015086294A (ja) * 2013-10-30 2015-05-07 株式会社クラレ 多孔質グラフト共重合体粒子、その製造方法及びそれを用いた吸着材
JP2017122653A (ja) * 2016-01-07 2017-07-13 日立化成株式会社 分離材及びカラム

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7048858B2 (en) * 2001-11-26 2006-05-23 Ge Healthcare Bio-Sciences Ab Post-modification of a porous support
JP2005510609A (ja) * 2001-11-26 2005-04-21 アメルシャム・バイオサイエンシーズ・アクチボラグ 多孔性支持体の後修飾
SE0201623D0 (sv) 2002-05-30 2002-05-30 Amersham Biosciences Ab Macroporous cross-linked polymer particles
SE0302509D0 (sv) 2003-09-19 2003-09-19 Amersham Biosciences Ab Matrix for separation of polyethers and method of separation
SE0303532D0 (sv) * 2003-12-23 2003-12-23 Amersham Biosciences Ab Purification of immunoglobulins
SE0401665D0 (sv) 2004-06-24 2004-06-24 Amersham Biosciences Ab Purification of immunoglobulins
US20070055013A1 (en) * 2005-02-21 2007-03-08 Noriho Kamiya Substrate and method of immobilizing protein
FR2884253B1 (fr) * 2005-04-08 2007-06-22 Univ Lille Sciences Tech Materiaux monolithiques fonctionnalisables
WO2008097154A1 (en) 2007-02-09 2008-08-14 Ge Healthcare Bio-Sciences Ab Liquid clarification
WO2008121042A1 (en) 2007-03-30 2008-10-09 Ge Healthcare Bio-Sciences Ab Purification of immunoglobulins
JP2011016036A (ja) * 2007-11-26 2011-01-27 Asahi Kasei Chemicals Corp タンパク吸着材料およびその製造方法
EP2285485B1 (de) * 2008-05-30 2014-04-23 Merck Patent GmbH Ce(iv) initiierte pfropfpolymerisation auf nicht hydroxylgruppenhaltigen polymeren
BRPI0914610B1 (pt) 2008-06-26 2018-03-06 3M Innovative Properties Company Suporte sólido com uma cadeia enxertada
CN102439438B (zh) * 2009-04-30 2015-02-25 大赛璐化学工业株式会社 光学异构体用分离剂
WO2015053701A1 (en) * 2013-10-10 2015-04-16 Ge Healthcare Bio-Sciences Ab Method for production of a chromatography material
EP3248677B1 (en) * 2015-01-19 2020-11-11 Hitachi Chemical Company, Ltd. Separation material
JP6939021B2 (ja) * 2017-03-30 2021-09-22 昭和電工マテリアルズ株式会社 分離材及びカラム
CN107446086B (zh) * 2017-09-06 2020-05-08 福建出入境检验检疫局检验检疫技术中心 一种六价铬印迹材料的制备方法

Citations (10)

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Publication number Priority date Publication date Assignee Title
JPS5272784A (en) * 1975-12-12 1977-06-17 Pharmacia Fine Chemicals Ab Dextrane derivative gel for electrophoresis separation
JPS55123610A (en) * 1979-03-17 1980-09-24 Nichiden Kagaku Kk Modified starch and its preparation
JPS57155212A (en) * 1981-03-20 1982-09-25 Kanegafuchi Chem Ind Co Ltd Modified polyvinyl chloride resin composition
JPS6263856A (ja) * 1985-09-13 1987-03-20 Japan Synthetic Rubber Co Ltd クロマトグラフイ−用充填剤の製造方法
JPH05170845A (ja) * 1991-12-20 1993-07-09 Nippon Paint Co Ltd 有機ポリマー微粒子およびその製法
JPH07171389A (ja) * 1993-12-21 1995-07-11 Mitsubishi Chem Corp 分離剤の製造方法
JPH07278204A (ja) * 1994-02-15 1995-10-24 Ciba Geigy Ag 不飽和炭水化物誘導体、そのポリマー及びその用途
WO1998040144A1 (en) * 1997-03-13 1998-09-17 Dionex Corporation Bifunctional crown ether-based cation-exchange stationary phase for liquid chromatography
US5929214A (en) * 1997-02-28 1999-07-27 Cornell Research Foundation, Inc. Thermally responsive polymer monoliths
JP2002022723A (ja) * 2000-07-05 2002-01-23 Mitsubishi Chemicals Corp 固体表面の修飾方法

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US4540742A (en) * 1982-11-12 1985-09-10 The B. F. Goodrich Company Graft copolymers and process for their preparation
DE3811042A1 (de) * 1988-03-31 1989-10-19 Merck Patent Gmbh Ionenaustauscher
US6022902A (en) 1989-10-31 2000-02-08 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Porous article with surface functionality and method for preparing same
EP0665867B1 (en) 1992-10-21 1998-01-07 Cornell Research Foundation, Inc. Pore-size selective chemical modification of porous materials
SE9303790D0 (sv) * 1993-11-17 1993-11-17 Pharmacia Lkb Biotech A method for separation and synthetic polymers that can be used as separation media in the method
US5503933A (en) * 1994-02-25 1996-04-02 Purdue Research Foundation Covalently bonded coatings
JP3499978B2 (ja) * 1995-08-17 2004-02-23 株式会社日清製粉グループ本社 逆相系分離膜
US6114466A (en) 1998-02-06 2000-09-05 Renal Tech International Llc Material for purification of physiological liquids of organism
TW594416B (en) * 2001-05-08 2004-06-21 Shipley Co Llc Photoimageable composition
JP2005510609A (ja) * 2001-11-26 2005-04-21 アメルシャム・バイオサイエンシーズ・アクチボラグ 多孔性支持体の後修飾

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5272784A (en) * 1975-12-12 1977-06-17 Pharmacia Fine Chemicals Ab Dextrane derivative gel for electrophoresis separation
JPS55123610A (en) * 1979-03-17 1980-09-24 Nichiden Kagaku Kk Modified starch and its preparation
JPS57155212A (en) * 1981-03-20 1982-09-25 Kanegafuchi Chem Ind Co Ltd Modified polyvinyl chloride resin composition
JPS6263856A (ja) * 1985-09-13 1987-03-20 Japan Synthetic Rubber Co Ltd クロマトグラフイ−用充填剤の製造方法
JPH05170845A (ja) * 1991-12-20 1993-07-09 Nippon Paint Co Ltd 有機ポリマー微粒子およびその製法
JPH07171389A (ja) * 1993-12-21 1995-07-11 Mitsubishi Chem Corp 分離剤の製造方法
JPH07278204A (ja) * 1994-02-15 1995-10-24 Ciba Geigy Ag 不飽和炭水化物誘導体、そのポリマー及びその用途
US5929214A (en) * 1997-02-28 1999-07-27 Cornell Research Foundation, Inc. Thermally responsive polymer monoliths
WO1998040144A1 (en) * 1997-03-13 1998-09-17 Dionex Corporation Bifunctional crown ether-based cation-exchange stationary phase for liquid chromatography
JP2002511924A (ja) * 1997-03-13 2002-04-16 ダイオネックス コーポレイション 液体クロマトグラフィー用の二官能クラウンエーテルをベースとする陽イオン交換固定相
JP2002022723A (ja) * 2000-07-05 2002-01-23 Mitsubishi Chemicals Corp 固体表面の修飾方法

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012032391A (ja) * 2010-07-28 2012-02-16 Rohm & Haas Co 改良されたクロマトグラフィー媒体の製造方法および使用方法
JP2012032390A (ja) * 2010-07-28 2012-02-16 Rohm & Haas Co 向上したクロマトグラフィー媒体の製造方法および使用方法
JP2012032392A (ja) * 2010-07-28 2012-02-16 Rohm & Haas Co クロマトグラフィー媒体性能を向上させるグラフト化方法
JP2013532829A (ja) * 2010-07-29 2013-08-19 イー・エム・デイー・ミリポア・コーポレイシヨン クロマトグラフィーの媒介性能を改善するためのグラフト法
WO2014069474A1 (ja) * 2012-10-30 2014-05-08 株式会社クラレ 多孔質グラフト共重合体粒子、その製造方法及びそれを用いた吸着材
US9943825B2 (en) 2012-10-30 2018-04-17 Kuraray Co., Ltd. Porous graft copolymer particles, method for producing same, and adsorbent material using same
JP2015086294A (ja) * 2013-10-30 2015-05-07 株式会社クラレ 多孔質グラフト共重合体粒子、その製造方法及びそれを用いた吸着材
JP2017122653A (ja) * 2016-01-07 2017-07-13 日立化成株式会社 分離材及びカラム

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Publication number Publication date
AU2002353728A1 (en) 2003-06-10
US7060187B2 (en) 2006-06-13
CA2464086C (en) 2011-01-18
AU2002353728B2 (en) 2008-04-10
CA2464086A1 (en) 2003-06-05
US20050065282A1 (en) 2005-03-24
WO2003046063A1 (en) 2003-06-05
EP1448684A1 (en) 2004-08-25

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