CA2434626A1 - Microorganisms and processes for enhanced production of pantothenate - Google Patents
Microorganisms and processes for enhanced production of pantothenate Download PDFInfo
- Publication number
- CA2434626A1 CA2434626A1 CA002434626A CA2434626A CA2434626A1 CA 2434626 A1 CA2434626 A1 CA 2434626A1 CA 002434626 A CA002434626 A CA 002434626A CA 2434626 A CA2434626 A CA 2434626A CA 2434626 A1 CA2434626 A1 CA 2434626A1
- Authority
- CA
- Canada
- Prior art keywords
- pantothenate
- microorganism
- deregulated
- biosynthetic pathway
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26299501P | 2001-01-19 | 2001-01-19 | |
| US26305301P | 2001-01-19 | 2001-01-19 | |
| US60/262,995 | 2001-01-19 | ||
| US60/263,053 | 2001-01-19 | ||
| US34763802P | 2002-01-11 | 2002-01-11 | |
| US60/347,638 | 2002-01-11 | ||
| PCT/US2002/000925 WO2002061108A2 (en) | 2001-01-19 | 2002-01-18 | Microorganisms and processes for enhanced production of pantothenate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2434626A1 true CA2434626A1 (en) | 2002-08-08 |
Family
ID=27401561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002434626A Abandoned CA2434626A1 (en) | 2001-01-19 | 2002-01-18 | Microorganisms and processes for enhanced production of pantothenate |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US7244593B2 (OSRAM) |
| EP (1) | EP1390519B1 (OSRAM) |
| JP (1) | JP4229700B2 (OSRAM) |
| KR (1) | KR20030075163A (OSRAM) |
| CN (1) | CN100529068C (OSRAM) |
| AT (1) | ATE347589T1 (OSRAM) |
| BR (1) | BR0206586A (OSRAM) |
| CA (1) | CA2434626A1 (OSRAM) |
| CZ (1) | CZ20031886A3 (OSRAM) |
| DE (1) | DE60216581T2 (OSRAM) |
| HU (1) | HU227432B1 (OSRAM) |
| IL (1) | IL156708A0 (OSRAM) |
| IN (2) | IN2003CH01278A (OSRAM) |
| MX (1) | MXPA03006343A (OSRAM) |
| NO (1) | NO20033240L (OSRAM) |
| PL (1) | PL369009A1 (OSRAM) |
| WO (1) | WO2002061108A2 (OSRAM) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8232081B2 (en) * | 1999-09-21 | 2012-07-31 | Basf Se | Methods and microorganisms for production of panto-compounds |
| BR0206587A (pt) | 2001-01-19 | 2005-12-13 | Basf Ag | Processo para a produção de uma composição de pantotenato livre de hmbpa, produto, composição de pantotenato livre de hmbpa, composição sintetizada por um microorganismo possuindo uma rota biossintética de pantotenato desregulada, microorganismo recombinante para a produção de composições de pantotenato livres de hmbpa, e, processo para a produção de uma composição de pantotenato: hmbpa seletivamente misturada |
| DE10106461A1 (de) * | 2001-02-13 | 2002-08-14 | Degussa | Verfahren zur fermentativen Herstellung von D-Pantothensäure und/oder deren Salzen |
| ATE350483T1 (de) | 2001-02-21 | 2007-01-15 | Basf Ag | Verfahren zur herstellung von d-pantothensäure und/oder salze als zusatz zu tierfuttermitteln |
| DE10108223A1 (de) | 2001-02-21 | 2002-10-10 | Basf Ag | Verfahren zur Herstellung von D-Pantothensäure und/oder deren Salze als Zusatz zu Tierfuttermitteln |
| EP1247868A3 (de) * | 2001-04-03 | 2002-10-30 | Degussa AG | Verfahren zur fermentativen Herstellung von D-Pantothensäure und/oder deren Salzen |
| EP1402046A1 (en) * | 2001-07-03 | 2004-03-31 | Degussa AG | Process for the fermentative preparation of d-pantothenic acid and/or salts thereof |
| DE10132178A1 (de) | 2001-07-03 | 2003-01-23 | Degussa | Verfahren zur fermantativen Herstellung von D-Pantothensäure und/oder deren Salzen |
| WO2004005525A2 (en) * | 2002-07-03 | 2004-01-15 | Basf Aktiengesellschaft | Microorganisms and processes for enhanced production of pantothenate |
| MXPA04012807A (es) * | 2002-07-03 | 2005-02-24 | Basf Ag | Microorganismos y proceso para la produccion aumentada de pantotenato. |
| CN1809631B (zh) * | 2003-06-18 | 2010-05-26 | 帝斯曼知识产权资产管理有限公司 | 用不能形成芽孢的微生物来生产泛酸盐/酯的方法 |
| DE10331291A1 (de) | 2003-07-10 | 2005-02-17 | Consortium für elektrochemische Industrie GmbH | Varianten der 3-Phosphoglyceratdehydrogenase mit reduzierter Hemmung durch L-Serin und dafür codierende Gene |
| DE102004026152A1 (de) * | 2004-05-28 | 2005-12-15 | Basf Ag | Fermentative Herstellung von Feinchemikalien |
| CN101448950B (zh) | 2006-05-16 | 2014-02-12 | 帝斯曼知识产权资产管理有限公司 | 用于生产泛醇的工艺 |
| EP2157174A1 (en) | 2008-08-12 | 2010-02-24 | DSM IP Assets B.V. | Increased production of pantothenate (vitamin B5) |
| MX2012004682A (es) | 2009-10-26 | 2012-09-07 | Hoffmann La Roche | Metodo para la produccion de una inmunoglobulina glicosilada. |
| CN102311966B (zh) * | 2010-06-30 | 2016-04-13 | 中国科学院青岛生物能源与过程研究所 | 用于合成脂肪醇的构建体，载体，蓝细菌，以及在蓝细菌中生产脂肪醇的方法 |
| WO2012175574A1 (en) | 2011-06-21 | 2012-12-27 | Dsm Ip Assets B.V. | Increased pantothenate (vitamin b5) production |
| WO2012175575A2 (en) | 2011-06-21 | 2012-12-27 | Dsm Ip Assets B.V. | Increased vitamin b5 production |
| CN104220587A (zh) | 2012-01-30 | 2014-12-17 | 麦兰特公司 | 从经基因改造的微生物生产黏康酸 |
| WO2014087184A1 (en) * | 2012-12-03 | 2014-06-12 | Metabolic Explorer | Neopentyl glycol fermentative production by a recombinant microorganism |
| KR20190003939A (ko) | 2016-03-02 | 2019-01-10 | 피티티지씨 이노베이션 아메리카 코포레이션 | 유전자 조작된 미생물로부터 개선된 뮤콘산 생산 |
| CN108456701B (zh) * | 2018-03-23 | 2020-10-16 | 精晶药业股份有限公司 | 一种d-泛解酸内酯的制备方法 |
| CN111534562A (zh) * | 2020-06-19 | 2020-08-14 | 南京欧信医药技术有限公司 | 一种d-泛解酸的制备方法 |
| CN112195143B (zh) * | 2020-09-24 | 2022-10-14 | 浙江工业大学 | 一种用于发酵法生产d-泛酸的菌株及发酵法生产d-泛酸的方法 |
| CN113416744B (zh) * | 2021-06-04 | 2022-05-20 | 浙江工业大学 | 一种d-泛解酸生产菌、构建方法及应用 |
| CN116024278B (zh) * | 2022-12-16 | 2024-05-07 | 黑龙江新和成生物科技有限公司 | 一种发酵法制备d-泛酸的方法 |
| WO2025113965A1 (en) * | 2023-11-29 | 2025-06-05 | Unilever Ip Holdings B.V. | Use of l-aspartate for improving production of pantothenate |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6787334B1 (en) * | 1998-10-09 | 2004-09-07 | Degussa Ag | Process for the preparation of pantothenic acid by amplification of nucleotide sequences which code for the ketopantoate reductase |
| DE19846499A1 (de) * | 1998-10-09 | 2000-04-20 | Degussa | Verfahren zur Herstellung von Pantothensäure durch Verstärkung von für Ketopantoat-Reduktase kodierenden Nukleotidsequenzen |
| DE19855313A1 (de) * | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentativen Herstellung von D-Pantothensäure durch Verstärkung des panD-Gens in Mikroorganismen |
| DE19855312A1 (de) * | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentativen Herstellung von D-Pantothensäure unter Verwendung coryneformer Bakterien |
| DE19855314A1 (de) * | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentiven Herstellung von D-Pantothensäure unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| EP1214420B1 (en) * | 1999-09-21 | 2016-03-23 | Basf Se | Methods and microorganisms for production of panto-compounds |
| BR0206587A (pt) * | 2001-01-19 | 2005-12-13 | Basf Ag | Processo para a produção de uma composição de pantotenato livre de hmbpa, produto, composição de pantotenato livre de hmbpa, composição sintetizada por um microorganismo possuindo uma rota biossintética de pantotenato desregulada, microorganismo recombinante para a produção de composições de pantotenato livres de hmbpa, e, processo para a produção de uma composição de pantotenato: hmbpa seletivamente misturada |
| EP1247868A3 (de) * | 2001-04-03 | 2002-10-30 | Degussa AG | Verfahren zur fermentativen Herstellung von D-Pantothensäure und/oder deren Salzen |
| EP1402046A1 (en) * | 2001-07-03 | 2004-03-31 | Degussa AG | Process for the fermentative preparation of d-pantothenic acid and/or salts thereof |
-
2002
- 2002-01-18 KR KR20037009544A patent/KR20030075163A/ko not_active Withdrawn
- 2002-01-18 MX MXPA03006343A patent/MXPA03006343A/es unknown
- 2002-01-18 WO PCT/US2002/000925 patent/WO2002061108A2/en active IP Right Grant
- 2002-01-18 CZ CZ20031886A patent/CZ20031886A3/cs unknown
- 2002-01-18 EP EP02709018A patent/EP1390519B1/en not_active Expired - Lifetime
- 2002-01-18 AT AT02709018T patent/ATE347589T1/de not_active IP Right Cessation
- 2002-01-18 CA CA002434626A patent/CA2434626A1/en not_active Abandoned
- 2002-01-18 US US10/466,641 patent/US7244593B2/en not_active Expired - Lifetime
- 2002-01-18 DE DE60216581T patent/DE60216581T2/de not_active Expired - Lifetime
- 2002-01-18 CN CNB028038576A patent/CN100529068C/zh not_active Expired - Fee Related
- 2002-01-18 PL PL02369009A patent/PL369009A1/xx not_active Application Discontinuation
- 2002-01-18 BR BR0206586-0A patent/BR0206586A/pt active Search and Examination
- 2002-01-18 HU HU0501185A patent/HU227432B1/hu not_active IP Right Cessation
- 2002-01-18 JP JP2002561662A patent/JP4229700B2/ja not_active Expired - Fee Related
- 2002-01-18 IL IL15670802A patent/IL156708A0/xx unknown
- 2002-01-19 IN IN1278CH2003 patent/IN2003CH01278A/en unknown
-
2003
- 2003-07-17 NO NO20033240A patent/NO20033240L/no not_active Application Discontinuation
- 2003-08-14 IN IN1280CH2003 patent/IN2003CH01280A/en unknown
-
2007
- 2007-07-16 US US11/879,143 patent/US20080166777A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20080166777A1 (en) | 2008-07-10 |
| CN100529068C (zh) | 2009-08-19 |
| CN1571837A (zh) | 2005-01-26 |
| WO2002061108A3 (en) | 2003-12-11 |
| EP1390519A2 (en) | 2004-02-25 |
| JP2004533213A (ja) | 2004-11-04 |
| WO2002061108A2 (en) | 2002-08-08 |
| KR20030075163A (ko) | 2003-09-22 |
| AU2002243526A (en) | 2002-08-12 |
| IN2003CH01280A (OSRAM) | 2005-11-18 |
| JP4229700B2 (ja) | 2009-02-25 |
| EP1390519B1 (en) | 2006-12-06 |
| BR0206586A (pt) | 2006-01-24 |
| US20040091979A1 (en) | 2004-05-13 |
| NO20033240D0 (no) | 2003-07-17 |
| DE60216581T2 (de) | 2007-09-27 |
| DE60216581D1 (de) | 2007-01-18 |
| PL369009A1 (en) | 2005-04-18 |
| CZ20031886A3 (cs) | 2003-10-15 |
| NO20033240L (no) | 2003-09-17 |
| HU227432B1 (hu) | 2011-06-28 |
| US7244593B2 (en) | 2007-07-17 |
| MXPA03006343A (es) | 2003-10-06 |
| HUP0501185A2 (en) | 2006-10-28 |
| IN2003CH01278A (OSRAM) | 2005-11-18 |
| ATE347589T1 (de) | 2006-12-15 |
| IL156708A0 (en) | 2004-01-04 |
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| FZDE | Discontinued |