CA2394539A1 - Agent de contraste fluorescent proche infrarouge et imagerie par fluorescence - Google Patents

Agent de contraste fluorescent proche infrarouge et imagerie par fluorescence Download PDF

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Publication number
CA2394539A1
CA2394539A1 CA002394539A CA2394539A CA2394539A1 CA 2394539 A1 CA2394539 A1 CA 2394539A1 CA 002394539 A CA002394539 A CA 002394539A CA 2394539 A CA2394539 A CA 2394539A CA 2394539 A1 CA2394539 A1 CA 2394539A1
Authority
CA
Canada
Prior art keywords
contrast agent
near infrared
infrared fluorescent
fluorescent contrast
fluorescence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002394539A
Other languages
English (en)
Other versions
CA2394539C (fr
Inventor
Naoto Miwa
Michihito Inagaki
Hiroaki Eguchi
Masafumi Okumura
Yoshio Inagaki
Toru Harada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Fujifilm Holdings Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2394539A1 publication Critical patent/CA2394539A1/fr
Application granted granted Critical
Publication of CA2394539C publication Critical patent/CA2394539C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Indole Compounds (AREA)
CA002394539A 1999-12-15 1999-12-15 Agent de contraste fluorescent proche infrarouge et imagerie par fluorescence Expired - Fee Related CA2394539C (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1999/009959 WO2001043781A1 (fr) 1999-12-15 1999-12-15 Agent de contraste fluorescent proche infrarouge et imagerie par fluorescence

Publications (2)

Publication Number Publication Date
CA2394539A1 true CA2394539A1 (fr) 2001-06-21
CA2394539C CA2394539C (fr) 2009-10-27

Family

ID=8167530

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002394539A Expired - Fee Related CA2394539C (fr) 1999-12-15 1999-12-15 Agent de contraste fluorescent proche infrarouge et imagerie par fluorescence

Country Status (19)

Country Link
EP (1) EP1237583A1 (fr)
JP (1) JP2003517025A (fr)
KR (1) KR20020082207A (fr)
CN (1) CN1217701C (fr)
AU (1) AU2097500A (fr)
BG (1) BG106822A (fr)
BR (1) BR9917587A (fr)
CA (1) CA2394539C (fr)
EA (1) EA200200635A1 (fr)
EE (1) EE200200321A (fr)
HU (1) HUP0204024A2 (fr)
IL (1) IL149798A0 (fr)
MX (1) MXPA02005806A (fr)
NO (1) NO328630B1 (fr)
PL (1) PL355891A1 (fr)
SK (1) SK8142002A3 (fr)
TR (1) TR200201567T2 (fr)
WO (1) WO2001043781A1 (fr)
YU (1) YU44402A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114459862A (zh) * 2022-01-13 2022-05-10 华腾实业（深圳）股份有限公司 一种高识别的真菌荧光染色液

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7682602B2 (en) * 2003-12-19 2010-03-23 Konica Minolta Medical & Graphic, Inc. Near-infrared fluorescent contrast medium
JP2005220045A (ja) * 2004-02-04 2005-08-18 Konica Minolta Medical & Graphic Inc 蛍光造影剤
JP5074044B2 (ja) 2007-01-18 2012-11-14 オリンパス株式会社 蛍光観察装置および蛍光観察装置の作動方法
US8344158B2 (en) * 2007-08-15 2013-01-01 Washington University Fluorescent polymethine cyanine dyes
US20090214436A1 (en) 2008-02-18 2009-08-27 Washington University Dichromic fluorescent compounds
JP2011046663A (ja) 2009-08-28 2011-03-10 Fujifilm Corp 近赤外蛍光造影剤
US8401618B2 (en) 2009-08-28 2013-03-19 Visen Medical, Inc. Systems and methods for tomographic imaging in diffuse media using a hybrid inversion technique
WO2011038006A1 (fr) 2009-09-22 2011-03-31 Visen Medical, Inc. Systèmes et procédés pour adaptation d'indice virtuelle de milieux diffusifs
EP2523596A4 (fr) * 2010-01-14 2015-02-25 Univ California Dispositifs, systèmes et procédés pour détecter et réduire ou empêcher l'entrée de médiateurs inflammatoires dans des conduits lactifères
GB201010878D0 (en) 2010-06-29 2010-08-11 Ge Healthcare As Dye compositiion and dye syntheses
EP2806781B1 (fr) 2012-01-23 2018-03-21 Washington University Systèmes et procédés d'imagerie
US10743768B2 (en) 2012-10-15 2020-08-18 Visen Medical, Inc. Systems, methods, and apparatus for imaging of diffuse media featuring cross-modality weighting of fluorescent and bioluminescent sources
US20170232119A1 (en) 2013-03-15 2017-08-17 Purdue Research Foundation Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors
JP6192799B2 (ja) 2013-03-15 2017-09-06 パーデュー・リサーチ・ファウンデーションＰｕｒｄｕｅ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ 腫瘍の標的画像化に使用される化合物にコンジュゲートしているアミノ酸連結基の合成および組成物
US10986997B2 (en) 2013-12-31 2021-04-27 Memorial Sloan Kettering Cancer Center Systems, methods, and apparatus for multichannel imaging of fluorescent sources in real time
KR20170094268A (ko) 2014-12-15 2017-08-17 메모리얼 슬로안-케터링 캔서 센터 향상된 신경-결합 선택성을 갖는 고리형 펩티드, 상기 고리형 펩티드와 결합된 나노입자, 및 실시간 생체내 신경 조직 영상화를 위한 이들의 용도
US10806804B2 (en) 2015-05-06 2020-10-20 Washington University Compounds having RD targeting motifs and methods of use thereof
TR201810532T4 (tr) * 2015-06-03 2018-08-27 Surgimab S A S Floresan konjügatlar.
CN105222828B (zh) * 2015-09-30 2017-05-24 东南大学 一种贴壁射流速度场和浓度场的同步测量装置与方法
WO2017106525A1 (fr) 2015-12-15 2017-06-22 Memorial Sloan Kettering Cancer Center Systèmes et procédés d'imagerie pour différenciation tissulaire, par exemple pour visualisation peropératoire
AU2017368005A1 (en) 2016-11-30 2019-06-20 Cornell University Inhibitor-functionalized ultrasmall nanoparticles and methods thereof
US11989803B2 (en) 2018-03-30 2024-05-21 Perkinelmer Health Sciences, Inc. Systems and methods for 3D reconstruction of anatomical organs and inclusions using short-wave infrared (SWIR) projection tomography
US11712482B2 (en) 2019-12-13 2023-08-01 Washington University Near infrared fluorescent dyes, formulations and related methods
US11964965B2 (en) * 2020-05-08 2024-04-23 On Target Laboratories, LLC Methods of manufacture and synthesis of fluorescent dye compounds and uses thereof
EP4015004A1 (fr) 2020-12-18 2022-06-22 Phi Pharma SA Peptides ramifiés spécifiques de protéoglycane

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2163393T3 (es) * 1990-05-15 2002-02-01 Hyperion Inc Porfirina fluorescente y ftalocianina fluorescente - derivados de polietilenglicol, poliol y sacaridos como sondas fluorescentes.
CN1093768C (zh) * 1995-01-30 2002-11-06 第一化学药品株式会社 诊断用标记物
JP2000095758A (ja) * 1998-09-18 2000-04-04 Schering Ag 近赤外蛍光造影剤および蛍光造影方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114459862A (zh) * 2022-01-13 2022-05-10 华腾实业（深圳）股份有限公司 一种高识别的真菌荧光染色液

Also Published As

Publication number Publication date
EE200200321A (et) 2003-10-15
TR200201567T2 (tr) 2002-11-21
MXPA02005806A (es) 2010-10-26
NO20022837L (no) 2002-06-14
JP2003517025A (ja) 2003-05-20
CN1384760A (zh) 2002-12-11
NO328630B1 (no) 2010-04-12
KR20020082207A (ko) 2002-10-30
YU44402A (sh) 2005-03-15
CN1217701C (zh) 2005-09-07
SK8142002A3 (en) 2002-12-03
CA2394539C (fr) 2009-10-27
EA200200635A1 (ru) 2002-12-26
AU2097500A (en) 2001-06-25
IL149798A0 (en) 2002-11-10
PL355891A1 (en) 2004-05-31
BR9917587A (pt) 2002-08-06
EP1237583A1 (fr) 2002-09-11
HUP0204024A2 (en) 2003-04-28
WO2001043781A1 (fr) 2001-06-21
BG106822A (bg) 2003-01-31
NO20022837D0 (no) 2002-06-14

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