EA199900302A1 - Композиция для иммуногистохимического окрашивания - Google Patents

Композиция для иммуногистохимического окрашивания

Info

Publication number
EA199900302A1
EA199900302A1 EA199900302A EA199900302A EA199900302A1 EA 199900302 A1 EA199900302 A1 EA 199900302A1 EA 199900302 A EA199900302 A EA 199900302A EA 199900302 A EA199900302 A EA 199900302A EA 199900302 A1 EA199900302 A1 EA 199900302A1
Authority
EA
Eurasian Patent Office
Prior art keywords
composition
cancer
immunohistochemical staining
diagnosis
group
Prior art date
Application number
EA199900302A
Other languages
English (en)
Other versions
EA002222B1 (ru
Inventor
Сеиити Сибамура
Сусуму Ито
Казухиро Такесако
Тацуро Иримура
Original Assignee
Дайити Пьюэр Кемикалз Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дайити Пьюэр Кемикалз Ко., Лтд. filed Critical Дайити Пьюэр Кемикалз Ко., Лтд.
Publication of EA199900302A1 publication Critical patent/EA199900302A1/ru
Publication of EA002222B1 publication Critical patent/EA002222B1/ru

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57446—Specifically defined cancers of stomach or intestine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Композиция для иммуногистохимического окрашивания, которая содержит диагностический маркер, содержащий антитело, связанное с флуоресцентной функциональной группой, и вещество, выбранное из группы, содержащей глицерофосфолипид, жирную кислоту и поверхностно-активное вещество, состоящее из производного сахарида. Композиция обладает прекрасной интенсивностью флюоресценции и не вызывает проблем, связанных с повреждением живых тканей и ДНК из-за облучения ультрафиолетовым излучением, и, следовательно, композиция применима для иммуногистохимического окрашивания in vivo. Например, она позволяет проводить эффективную и безопасную раннюю псевдовнутреннюю диагностику злокачественных новообразований эпителиальных тканей, таких как рак пищевода, рак желудка и рак толстого кишечника, путем применения инфракрасного эндоскопа или другого или выявление и диагностику патологических изменений в ходе хирургической операции.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199900302A 1996-09-19 1997-09-18 Композиция для иммуногистохимического окрашивания EA002222B1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP24678296 1996-09-19
JP34788696 1996-12-26
JP4551697 1997-02-28
PCT/JP1997/003306 WO1998012560A1 (fr) 1996-09-19 1997-09-18 Composition de coloration immunohistochimique

Publications (2)

Publication Number Publication Date
EA199900302A1 true EA199900302A1 (ru) 1999-10-28
EA002222B1 EA002222B1 (ru) 2002-02-28

Family

ID=27292262

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900302A EA002222B1 (ru) 1996-09-19 1997-09-18 Композиция для иммуногистохимического окрашивания

Country Status (10)

Country Link
EP (1) EP0935139B1 (ru)
KR (1) KR20000036240A (ru)
CN (1) CN1130563C (ru)
AT (1) ATE282827T1 (ru)
AU (1) AU719676B2 (ru)
CA (1) CA2266405A1 (ru)
DE (1) DE69731654T2 (ru)
EA (1) EA002222B1 (ru)
NO (1) NO991317L (ru)
WO (1) WO1998012560A1 (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8080097B2 (en) 2003-11-06 2011-12-20 Hewlett-Packard Development Company, L.P. System and a method for the creation of edible, optically invisible images
CN101203248A (zh) * 2005-06-21 2008-06-18 马林克罗特公司 光学成像造影剂
CN100345555C (zh) * 2005-07-18 2007-10-31 江苏省中医药研究院 一种止痛巴布膏的制备方法
RU2546293C2 (ru) 2010-02-05 2015-04-10 Нитирей Байосайенсиз Инк. Раствор для предварительной обработки для иммуногистохимического окрашивания и конденсированный раствор
JP5573499B2 (ja) * 2010-08-30 2014-08-20 コニカミノルタ株式会社 蛍光測定方法
WO2017160639A1 (en) * 2016-03-14 2017-09-21 Massachusetts Institute Of Technology Device and method for imaging shortwave infrared fluorescence
RU2707377C1 (ru) * 2019-03-19 2019-11-26 федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр имени В.А. Алмазова" Министерства здравоохранения Российской Федерации Способ интраоперационной визуализации нарушения герметичности аппаратного шва при продольной резекции желудка

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5547836A (en) * 1990-08-30 1996-08-20 Tropix, Inc. Enhancement of chemiluminescent assays
US5521061A (en) * 1992-07-17 1996-05-28 Aprogenex, Inc. Enhancement of probe signal in nucleic acid-mediated in-situ hybridization studies
EP0697106B1 (de) * 1993-05-03 1997-04-02 Roche Diagnostics GmbH Elektrochemilumineszenzverfahren
AU2775395A (en) * 1994-07-15 1996-02-16 Abbott Laboratories Chemiluminescent signal enhancement
JP3669752B2 (ja) * 1995-01-30 2005-07-13 第一化学薬品株式会社 診断用マーカー

Also Published As

Publication number Publication date
KR20000036240A (ko) 2000-06-26
ATE282827T1 (de) 2004-12-15
NO991317D0 (no) 1999-03-18
EA002222B1 (ru) 2002-02-28
CN1238042A (zh) 1999-12-08
EP0935139B1 (en) 2004-11-17
WO1998012560A1 (fr) 1998-03-26
DE69731654D1 (de) 2004-12-23
CA2266405A1 (en) 1998-03-26
EP0935139A1 (en) 1999-08-11
NO991317L (no) 1999-05-19
EP0935139A4 (en) 2002-01-30
DE69731654T2 (de) 2005-12-01
AU4318897A (en) 1998-04-14
CN1130563C (zh) 2003-12-10
AU719676B2 (en) 2000-05-18

Similar Documents

Publication Publication Date Title
Doiron et al. Fluorescence bronchoscopy for detection of lung cancer
JP6301929B2 (ja) 自動器具
JP4954573B2 (ja) 内視鏡システム
CN107072505A (zh) 用于组织氧合的绘制的装置、系统和方法
CN107209118A (zh) 在自体荧光存在下生物材料中目标荧光团的成像
BG107411A (en) Near infrared fluorescent contrast agent and fluorescence imaging
JP2004503279A (ja) 周辺光条件下のインビボ誘導信号の光学画像化
CN201578365U (zh) 一种肿瘤外科术中荧光导航系统
WO2000021576A3 (en) Method for viewing tumor tissue located within a body cavity
DE69726135D1 (de) Fluoreszierende chelate als gewebespezifische bildgebende mittel
CN107076724A (zh) 生物体染色剂
YU44402A (sh) Fluorescentno kontrastno sredstvo u bliskoj infracrvenoj oblasti i fluorescentno snimanje
US20080039695A1 (en) Fluorescence endoscope system, fluoroscopy apparatus, fluoroscopy method, fluorescence-information processing apparatus, and fluorescence-information processing method
EA199900302A1 (ru) Композиция для иммуногистохимического окрашивания
JP2004525697A (ja) 腫瘍組織の光力学的診断用のデバイス及び方法
KR20150075053A (ko) 형광유도 수술(ｆｇｓ)용 휴대형 디지털 이미징 시스템
Baumgartner et al. Photodynamic diagnosis following intravesical instillation of aminolevulinic acid (ALA): first clinical experiences in urology
EP2515746B1 (en) Method of calibration
Baumgartner et al. Delta-ALA-assisted fluorescence detection of cancer in the urinary bladder
JP2008069107A (ja) 内視鏡用組織蛍光染色剤
Avramaov et al. Potential and current uses of luminescence in medical diagnosis
Mizeret et al. Endoscopic tissue fluorescence life-time imaging by frequency doamin light-induced fluorescence
Müller et al. Demonstration of elastic fibres with reagents for detection of magnesium.
Yang et al. Fluorescence spectroscopy of dermal wounds in rats
RU2041952C1 (ru) Способ обнаружения анаэробных бактерий в биологическом субстрате

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU