CA2379005A1 - Low hygroscopic aripiprazole drug substance and processes for the preparation thereof - Google Patents

Low hygroscopic aripiprazole drug substance and processes for the preparation thereof Download PDF

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Publication number
CA2379005A1
CA2379005A1 CA 2379005 CA2379005A CA2379005A1 CA 2379005 A1 CA2379005 A1 CA 2379005A1 CA 2379005 CA2379005 CA 2379005 CA 2379005 A CA2379005 A CA 2379005A CA 2379005 A1 CA2379005 A1 CA 2379005A1
Authority
CA
Canada
Prior art keywords
aripiprazole
hydrate
anhydride crystals
aripiprazole anhydride
crystals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2379005
Other languages
English (en)
French (fr)
Inventor
Yoshihiro Nishioka
Tsutomu Fujimura
Takuji Bando
Noriyuki Kobayashi
Makoto Ishigami
Youichi Taniguchi
Tsuyoshi Yabuuchi
Satoshi Aoki
Junichi Kawasaki
Kiyoshi Fujimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19112920&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2379005(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to ARP020103511A priority Critical patent/AR033485A1/es
Priority to MYPI20023512A priority patent/MY138669A/en
Priority to PE2008001435A priority patent/PE20090124A1/es
Priority to PE2002000922A priority patent/PE20030445A1/es
Priority to TW091121771A priority patent/TWI318572B/zh
Priority to TW098116881A priority patent/TWI332839B/zh
Priority to CN2008101254071A priority patent/CN101423492B/zh
Priority to UA2003010503A priority patent/UA80802C2/xx
Priority to DK08000359.3T priority patent/DK1927356T3/da
Priority to PL417178A priority patent/PL230869B1/pl
Priority to EP08000358.5A priority patent/EP1925308B1/en
Priority to PL393598A priority patent/PL221521B1/pl
Priority to CN201510615759.5A priority patent/CN105267151A/zh
Priority to CN02801754A priority patent/CN1463191A/zh
Priority to CN2008101254103A priority patent/CN101434574B/zh
Priority to CN201410466919.XA priority patent/CN104306337A/zh
Priority to AT02782507T priority patent/ATE322269T1/de
Priority to CNA2008101254118A priority patent/CN101434575A/zh
Priority to CNA2005100785991A priority patent/CN1699346A/zh
Priority to EP16169141.5A priority patent/EP3081216A1/en
Priority to PL393608A priority patent/PL219564B1/pl
Priority to RU2003101334/15A priority patent/RU2259366C2/ru
Priority to JP2002279085A priority patent/JP3760264B2/ja
Priority to CN201510333215.XA priority patent/CN104945321A/zh
Priority to ES08000357T priority patent/ES2343219T3/es
Priority to DE60235995T priority patent/DE60235995D1/de
Priority to PL360900A priority patent/PL225415B1/pl
Priority to CA2688915A priority patent/CA2688915C/en
Priority to SI200230905T priority patent/SI1927355T1/sl
Priority to SI200230337T priority patent/SI1330249T1/sl
Priority to GEAP2002005101 priority patent/GEP20053457B/en
Priority to AT08000359T priority patent/ATE465737T1/de
Priority to BR0205391-8A priority patent/BR0205391A/pt
Priority to CN201410468156.2A priority patent/CN104306374A/zh
Priority to AT08000357T priority patent/ATE465736T1/de
Priority to CA002688860A priority patent/CA2688860A1/en
Priority to DE60236231T priority patent/DE60236231D1/de
Priority to PT80003585T priority patent/PT1925308T/pt
Priority to SI200230904T priority patent/SI1927356T1/sl
Priority to PT04002427T priority patent/PT1419776E/pt
Priority to CN200610006215XA priority patent/CN1817882B/zh
Priority to CN201610186509.9A priority patent/CN105832677A/zh
Priority to CN2013100996412A priority patent/CN103191118A/zh
Priority to PT08000359T priority patent/PT1927356E/pt
Priority to CN201710019464.0A priority patent/CN106692151A/zh
Priority to DK08000357.7T priority patent/DK1927355T3/da
Priority to UAA200612812 priority patent/UA84764C2/uk
Priority to EP02782507A priority patent/EP1330249B1/en
Priority to CN201410053619.9A priority patent/CN103751093A/zh
Priority to DK02782507T priority patent/DK1330249T3/da
Priority to CN2009101474907A priority patent/CN101574347B/zh
Priority to CN201610811822.7A priority patent/CN106420627A/zh
Priority to SI200230903T priority patent/SI1419776T2/sl
Priority to ES02782507T priority patent/ES2261750T3/es
Priority to PL393603A priority patent/PL221536B1/pl
Priority to CA2689052A priority patent/CA2689052C/en
Priority to CA2688934A priority patent/CA2688934C/en
Priority to CN201610811281.8A priority patent/CN106420640A/zh
Priority to CN201310191361.4A priority patent/CN103288727B/zh
Priority to PT02782507T priority patent/PT1330249E/pt
Priority to DE60236383T priority patent/DE60236383D1/de
Priority to DE60236229T priority patent/DE60236229D1/de
Priority to PT08000357T priority patent/PT1927355E/pt
Priority to AT04002427T priority patent/ATE464050T1/de
Priority to AT08000360T priority patent/ATE467416T1/de
Priority to CN201310728318.7A priority patent/CN103755632B/zh
Priority to PCT/JP2002/009858 priority patent/WO2003026659A1/en
Priority to CNA2008101254086A priority patent/CN101423493A/zh
Priority to EP08000357A priority patent/EP1927355B1/en
Priority to ES08000360T priority patent/ES2343602T3/es
Priority to ES08000358.5T priority patent/ES2596354T3/es
Priority to ES08000359T priority patent/ES2343220T3/es
Priority to CA2426921A priority patent/CA2426921C/en
Priority to IL15383802A priority patent/IL153838A0/xx
Priority to CN201410053617.XA priority patent/CN103751118A/zh
Priority to AU2002334413A priority patent/AU2002334413C1/en
Priority to PT08000360T priority patent/PT1927357E/pt
Priority to US10/333,244 priority patent/US20040058935A1/en
Priority to PL393596A priority patent/PL393596A1/pl
Priority to CA2713466A priority patent/CA2713466C/en
Priority to EP08000359A priority patent/EP1927356B1/en
Priority to CN2009101474930A priority patent/CN101579344B/zh
Priority to CN200910266341A priority patent/CN101792415A/zh
Priority to DK08000360.1T priority patent/DK1927357T3/da
Priority to LTEP08000358.5T priority patent/LT1925308T/lt
Priority to CN201410053920.XA priority patent/CN103751119A/zh
Priority to CN2009101474911A priority patent/CN101574348B/zh
Priority to CN2008101254090A priority patent/CN101434573B/zh
Priority to MXPA03000440A priority patent/MXPA03000440A/es
Priority to EP08000360A priority patent/EP1927357B1/en
Priority to DE60210409T priority patent/DE60210409T2/de
Priority to KR10-2004-7007990A priority patent/KR100530731B1/ko
Priority to CN2009101474926A priority patent/CN101579343B/zh
Priority to CN2012100054661A priority patent/CN102579446A/zh
Priority to DK08000358.5T priority patent/DK1925308T3/en
Priority to ES04002427.5T priority patent/ES2343179T5/es
Priority to PL393607A priority patent/PL393607A1/pl
Priority to SI200230906T priority patent/SI1927357T1/sl
Priority to CA2689051A priority patent/CA2689051C/en
Priority to PL393601A priority patent/PL219565B1/pl
Priority to DK04002427.5T priority patent/DK1419776T4/en
Priority to HU0600141A priority patent/HUP0600141A3/hu
Priority to KR10-2003-7000818A priority patent/KR100490222B1/ko
Priority to EP04002427.5A priority patent/EP1419776B2/en
Priority to IL153838A priority patent/IL153838A/en
Priority to NO20030247A priority patent/NO328134B1/no
Publication of CA2379005A1 publication Critical patent/CA2379005A1/en
Priority to HK16111449.6A priority patent/HK1223043A1/zh
Priority to HK15103617.0A priority patent/HK1203060A1/xx
Priority to HK15103616.1A priority patent/HK1203059A1/xx
Priority to JP2004156130A priority patent/JP3750023B2/ja
Priority to JP2005341187A priority patent/JP4614870B2/ja
Priority to ARP060103919A priority patent/AR056503A2/es
Priority to HK06113738.4A priority patent/HK1092808A1/xx
Priority to US11/790,606 priority patent/US7910589B2/en
Priority to US11/790,603 priority patent/US20070213343A1/en
Priority to US11/790,605 priority patent/US8017615B2/en
Priority to US11/790,604 priority patent/US8399469B2/en
Priority to US11/797,019 priority patent/US20070203150A1/en
Priority to US11/797,024 priority patent/US20070203151A1/en
Priority to US11/797,030 priority patent/US20070203152A1/en
Priority to IL188455A priority patent/IL188455A0/en
Priority to NO20081626A priority patent/NO336264B1/no
Priority to NO20081632A priority patent/NO336262B1/no
Priority to NO20081633A priority patent/NO20081633L/no
Priority to NO20081627A priority patent/NO336265B1/no
Priority to NO20081631A priority patent/NO336263B1/no
Priority to NO20091689A priority patent/NO336679B1/no
Priority to HK09107690.9A priority patent/HK1129891A1/xx
Priority to HK09107688.3A priority patent/HK1129889A1/xx
Priority to ARP090103228A priority patent/AR073111A2/es
Priority to HK10100650.9A priority patent/HK1136961A1/xx
Priority to HK10100635.9A priority patent/HK1136958A1/xx
Priority to HK10100638.6A priority patent/HK1136959A1/xx
Priority to HK10100649.3A priority patent/HK1136960A1/xx
Priority to IL204707A priority patent/IL204707A/en
Priority to CL2010000405A priority patent/CL2010000405A1/es
Priority to CY20101100530T priority patent/CY1110212T1/el
Priority to CY20101100529T priority patent/CY1110208T1/el
Priority to CY20101100531T priority patent/CY1110070T1/el
Priority to CY20101100614T priority patent/CY1110244T1/el
Priority to ARP100102387A priority patent/AR077635A2/es
Priority to US13/067,750 priority patent/US8642760B2/en
Priority to US13/067,838 priority patent/US8901303B2/en
Priority to US13/217,636 priority patent/US8703772B2/en
Priority to US13/350,117 priority patent/US8580796B2/en
Priority to US13/476,758 priority patent/US8901130B2/en
Priority to US13/476,773 priority patent/US8703773B2/en
Priority to ARP120102986A priority patent/AR087544A2/es
Priority to US13/749,753 priority patent/US8993761B2/en
Priority to IL225902A priority patent/IL225902A0/en
Priority to US14/049,777 priority patent/US9359302B2/en
Priority to HK13114439.5A priority patent/HK1187048A1/zh
Priority to PH12014500782A priority patent/PH12014500782A1/en
Priority to HK14109483.9A priority patent/HK1196128A1/zh
Priority to IL234770A priority patent/IL234770A0/en
Priority to NO20141193A priority patent/NO337844B1/no
Priority to US14/624,595 priority patent/US10150735B2/en
Priority to HK15111240.8A priority patent/HK1210468A1/xx
Priority to HK16103439.5A priority patent/HK1215397A1/zh
Priority to US15/149,522 priority patent/US20160251315A1/en
Priority to CY20161101119T priority patent/CY1118195T1/el
Priority to US16/169,255 priority patent/US20190225584A1/en
Priority to US16/718,281 priority patent/US20200123110A1/en
Priority to US17/160,716 priority patent/US20210395204A1/en
Abandoned legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
CA 2379005 2001-09-25 2002-03-27 Low hygroscopic aripiprazole drug substance and processes for the preparation thereof Abandoned CA2379005A1 (en)

Priority Applications (164)

Application Number Priority Date Filing Date Title
ARP020103511A AR033485A1 (es) 2001-09-25 2002-09-18 Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma
MYPI20023512A MY138669A (en) 2001-09-25 2002-09-20 Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
PE2008001435A PE20090124A1 (es) 2001-09-25 2002-09-20 Composicion farmaceutica que comprende cristales de aripiprazol b de baja higroscopicidad y procedimiento de preparacion de la misma
PE2002000922A PE20030445A1 (es) 2001-09-25 2002-09-20 Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma
TW091121771A TWI318572B (en) 2001-09-25 2002-09-23 Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
TW098116881A TWI332839B (en) 2001-09-25 2002-09-23 Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
CN2008101254071A CN101423492B (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
UA2003010503A UA80802C2 (en) 2001-09-25 2002-09-25 Low hygroscopic aripiprazole drug substance and process for the preparation thereof
DK08000359.3T DK1927356T3 (da) 2001-09-25 2002-09-25 Medikamentsubstans med lav hygroskopisk aripiprazol (krystal D) og fremgangsmåder til fremstilling deraf
PL417178A PL230869B1 (pl) 2001-09-25 2002-09-25 Hydrat A aripiprazolu i sposób jego wytwarzania
EP08000358.5A EP1925308B1 (en) 2001-09-25 2002-09-25 Pharmaceutical solid oral aripiprazole preparation and processes for the preparation thereof
PL393598A PL221521B1 (pl) 2001-09-25 2002-09-25 Kryształy F bezwodnego aripiprazolu i sposób ich wytwarzania oraz zawierające je kompozycja farmaceutyczna i farmaceutyczny stały preparat doustny
CN201510615759.5A CN105267151A (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
CN02801754A CN1463191A (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
CN2008101254103A CN101434574B (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
CN201410466919.XA CN104306337A (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
AT02782507T ATE322269T1 (de) 2001-09-25 2002-09-25 Aripiprazole wirkstoff mit niedriger hygroskopie und verfahren zu ihrer herstellung
CNA2008101254118A CN101434575A (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
CNA2005100785991A CN1699346A (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
EP16169141.5A EP3081216A1 (en) 2001-09-25 2002-09-25 Pharmaceutical solid oral aripiprazole preparation and processes for the preparation thereof
PL393608A PL219564B1 (pl) 2001-09-25 2002-09-25 Kryształy E bezwodnego aripiprazolu, sposób ich wytwarzania, kompozycja farmaceutyczna i farmaceutyczny stały preparat doustny zawierające kryształy E bezwodnego aripiprazolu
RU2003101334/15A RU2259366C2 (ru) 2001-09-25 2002-09-25 Арипипразоловое лекарственное средство с низкой гигроскопичностью и способы его получения
JP2002279085A JP3760264B2 (ja) 2001-09-25 2002-09-25 アリピプラゾール水和物、アリピプラゾール無水物結晶、それらの製造方法及びそれらを含む製剤
CN201510333215.XA CN104945321A (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
ES08000357T ES2343219T3 (es) 2001-09-25 2002-09-25 Medicamento a base de aripiprazol (cristal f) que tiene higroscopicidad reducida y su procedimiento de preparacion.
DE60235995T DE60235995D1 (de) 2001-09-25 2002-09-25 Aripiprazole Wirkstoff mit niedriger Hygroskopie und Verfahren zu ihrer Herstellung
PL360900A PL225415B1 (pl) 2001-09-25 2002-09-25 Kryształy B bezwodnego aripiprazolu i sposób ich wytwarzania, kompozycja farmaceutyczna, farmaceutyczny stały preparat doustny i sposób jego wytwarzania
CA2688915A CA2688915C (en) 2001-09-25 2002-09-25 Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
SI200230905T SI1927355T1 (sl) 2001-09-25 2002-09-25 Zdravilna snov slabo higroskopnega aripiprazola (kristal f) in postopki za njeno pripravo
SI200230337T SI1330249T1 (sl) 2001-09-25 2002-09-25 Zdravilna snov slabo higroskopnega aripiprazola in postopki za njeno pripravo
GEAP2002005101 GEP20053457B (en) 2001-09-25 2002-09-25 Low Hygroscopic Aripiprazole Drug Substance and Processes for Preparation Thereof
AT08000359T ATE465737T1 (de) 2001-09-25 2002-09-25 Gering hygroskopische aripiprazol-substanz (kristal d) und herstellungsverfahren
BR0205391-8A BR0205391A (pt) 2001-09-25 2002-09-25 Hidrato a de aripiprazol, processo para a preparação do hidrato a, substância de medicamento de aripiprazol de hogroscopicidade baixa, cristais de anidro de aripiprazol b, processos para a preparação de cristais de anidrido de aripiprazol b e para a preparação de uma preparação oral sólida farmacêutica, uso de cristais de anidrido de aripiprazol b, medicamento para tratar a esquizofrenia ou os sintomas associados com a esquizofrenia, processo para preparação de grânulos, preparação oral sólida farmacêutica, cristais de anidrido de aripiprazol c até g, processo para a preparação de cristais de anidridro de aripiprazol c até g, e, composição farmacêutica.
CN201410468156.2A CN104306374A (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
AT08000357T ATE465736T1 (de) 2001-09-25 2002-09-25 Gering hygroskopische aripiprazol-substanz (kristal f) und herstellungsverfahren
CA002688860A CA2688860A1 (en) 2001-09-25 2002-09-25 Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
DE60236231T DE60236231D1 (de) 2001-09-25 2002-09-25 Gering hygroskopische Aripiprazol-Substanz (Kristal D) und Herstellungsverfahren
PT80003585T PT1925308T (pt) 2001-09-25 2002-09-25 Preparação de aripiprazole oral sólida farmacêutica e processos para a sua preparação
SI200230904T SI1927356T1 (sl) 2001-09-25 2002-09-25 Zdravilna snov slabo higroskopnega aripiprazola (kristal d) in postopki za njeno pripravo
PT04002427T PT1419776E (pt) 2001-09-25 2002-09-25 Aripiprazole de baixa higroscopicidade e processos para a sua preparação
CN200610006215XA CN1817882B (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
CN201610186509.9A CN105832677A (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
CN2013100996412A CN103191118A (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
PT08000359T PT1927356E (pt) 2001-09-25 2002-09-25 Substância de fármaco aripiprazole (cristal d) com baixa higroscopicidade e processos para a sua preparação
CN201710019464.0A CN106692151A (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
DK08000357.7T DK1927355T3 (da) 2001-09-25 2002-09-25 Medikamentsubstans med lav hygroskopisk aripiprazol (krystal F) og fremgangsmåder til fremstilling deraf
UAA200612812 UA84764C2 (en) 2001-09-25 2002-09-25 Low hygroscopic aripiprazole drug substance and process for the preparation thereof
EP02782507A EP1330249B1 (en) 2001-09-25 2002-09-25 Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
CN201410053619.9A CN103751093A (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
DK02782507T DK1330249T3 (da) 2001-09-25 2002-09-25 Aripiprazol-lægemiddelstof med lav hygroskopicitet og fremgangsmåder til fremstilling deraf
CN2009101474907A CN101574347B (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
CN201610811822.7A CN106420627A (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
SI200230903T SI1419776T2 (sl) 2001-09-25 2002-09-25 Zdravilna snov slabo higroskopnega aripiprazola in postopki za njeno pripravo
ES02782507T ES2261750T3 (es) 2001-09-25 2002-09-25 Substancia farmaceutica de aripiprazol que tiene una higroscopicidad reducida y metodos de preparacion asociados.
PL393603A PL221536B1 (pl) 2001-09-25 2002-09-25 Kryształy C bezwodnego aripiprazolu i sposób ich wytwarzania oraz zawierające je kompozycja farmaceutyczna i farmaceutyczny stały preparat doustny
CA2689052A CA2689052C (en) 2001-09-25 2002-09-25 Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
CA2688934A CA2688934C (en) 2001-09-25 2002-09-25 Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
CN201610811281.8A CN106420640A (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
CN201310191361.4A CN103288727B (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
PT02782507T PT1330249E (pt) 2001-09-25 2002-09-25 Substancia farmaceutica de aripiprazole fracamente higroscopica e processos para a preparacao da mesma
DE60236383T DE60236383D1 (de) 2001-09-25 2002-09-25 Gering hygroskopische Aripiprazol-Substanz (Kristal E) und Herstellungsverfahren
DE60236229T DE60236229D1 (de) 2001-09-25 2002-09-25 Gering hygroskopische Aripiprazol-Substanz (Kristal F) und Herstellungsverfahren
PT08000357T PT1927355E (pt) 2001-09-25 2002-09-25 Substância de fármaco aripiprazole (cristal f) com baixa higroscopicidade e processos para a sua preparação
AT04002427T ATE464050T1 (de) 2001-09-25 2002-09-25 Aripiprazole wirkstoff mit niedriger hygroskopie und verfahren zu ihrer herstellung
AT08000360T ATE467416T1 (de) 2001-09-25 2002-09-25 Gering hygroskopische aripiprazol-substanz (kristal e) und herstellungsverfahren
CN201310728318.7A CN103755632B (zh) 2001-09-25 2002-09-25 低吸湿性阿立哌唑药物及其制备方法
PCT/JP2002/009858 WO2003026659A1 (en) 2001-09-25 2002-09-25 Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
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Cited By (1)

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US8039621B2 (en) 2006-10-24 2011-10-18 Cambrex Charles City, Inc. Process for preparing anhydrous Aripirazole type I

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8039621B2 (en) 2006-10-24 2011-10-18 Cambrex Charles City, Inc. Process for preparing anhydrous Aripirazole type I

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