CA2363695A1 - Dopamine d1 receptor agonist compounds - Google Patents
Dopamine d1 receptor agonist compounds Download PDFInfo
- Publication number
- CA2363695A1 CA2363695A1 CA002363695A CA2363695A CA2363695A1 CA 2363695 A1 CA2363695 A1 CA 2363695A1 CA 002363695 A CA002363695 A CA 002363695A CA 2363695 A CA2363695 A CA 2363695A CA 2363695 A1 CA2363695 A1 CA 2363695A1
- Authority
- CA
- Canada
- Prior art keywords
- hydrogen
- tetrahydro
- dopamine
- halogen
- chloro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9903671.7 | 1999-02-17 | ||
| GBGB9903671.7A GB9903671D0 (en) | 1999-02-17 | 1999-02-17 | Dopamine D-1 receptor agonist compounds |
| PCT/GB2000/000570 WO2000049000A1 (en) | 1999-02-17 | 2000-02-17 | Dopamine d1 receptor agonist compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2363695A1 true CA2363695A1 (en) | 2000-08-24 |
Family
ID=10847990
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002363695A Abandoned CA2363695A1 (en) | 1999-02-17 | 2000-02-17 | Dopamine d1 receptor agonist compounds |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1157009A1 (es) |
| JP (1) | JP2002537288A (es) |
| KR (1) | KR20010108228A (es) |
| CN (1) | CN1142916C (es) |
| AU (1) | AU767332B2 (es) |
| BR (1) | BR0008329A (es) |
| CA (1) | CA2363695A1 (es) |
| CZ (1) | CZ20012973A3 (es) |
| EA (1) | EA004745B1 (es) |
| GB (1) | GB9903671D0 (es) |
| HU (1) | HUP0200057A3 (es) |
| IL (1) | IL144810A0 (es) |
| MX (1) | MXPA01008294A (es) |
| NO (1) | NO20013978D0 (es) |
| PL (1) | PL349838A1 (es) |
| WO (1) | WO2000049000A1 (es) |
| ZA (1) | ZA200106478B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0130576D0 (en) * | 2001-12-20 | 2002-02-06 | Cenes Ltd | Dopamine D1 receptor agonist pro-drug compounds & derivatives |
| KR101594898B1 (ko) | 2005-07-15 | 2016-02-18 | 알바니 몰레큘라 리써치, 인크. | 아릴- 및 헤테로아릴-치환된 테트라히드로벤자제핀, 및 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도 |
| AU2006278514A1 (en) * | 2005-08-03 | 2007-02-15 | Mia Levite | Killing human lymphoma and leukemia cancer cells and TCR-activated normal human cells by dopamine D1R agonists |
| CN101684096A (zh) * | 2008-09-23 | 2010-03-31 | 中国科学院上海药物研究所 | 一类新型苯并氮杂卓类化合物及其制备方法和用途 |
| CN102276531A (zh) * | 2011-05-30 | 2011-12-14 | 扬子江药业集团广州海瑞药业有限公司 | 一种甲磺酸非诺多泮的制备方法 |
| RS59018B1 (sr) | 2013-06-27 | 2019-08-30 | Pfizer | Heteroaromatična jedinjenja i njihova upotreba kao dopamin d1 liganada |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1561305A (en) * | 1975-07-02 | 1980-02-20 | Smithkline Corp | Benzazepine derivatives and pharmeceutical compositions containing them |
| US4111957A (en) * | 1977-02-02 | 1978-09-05 | Smithkline Corporation | Substituted 1-thienyl and furyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds |
| US4265889A (en) * | 1978-05-05 | 1981-05-05 | Smithkline Corporation | 6-Lower alkyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines |
| US4707483A (en) * | 1985-12-20 | 1987-11-17 | Smithkline Beckman Corporation | 1-phenyl-3-benzazepines and their use for treating gastrointestinal motility disorders |
| US4861771A (en) * | 1989-01-27 | 1989-08-29 | Smithkline Beckman Corporation | Carbamates of 6-chloro-7,8-dihydroxy-1-(4'-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine as prodrugs |
-
1999
- 1999-02-17 GB GBGB9903671.7A patent/GB9903671D0/en not_active Ceased
-
2000
- 2000-02-17 PL PL00349838A patent/PL349838A1/xx not_active Application Discontinuation
- 2000-02-17 EA EA200100783A patent/EA004745B1/ru not_active IP Right Cessation
- 2000-02-17 CA CA002363695A patent/CA2363695A1/en not_active Abandoned
- 2000-02-17 IL IL14481000A patent/IL144810A0/xx unknown
- 2000-02-17 MX MXPA01008294A patent/MXPA01008294A/es unknown
- 2000-02-17 HU HU0200057A patent/HUP0200057A3/hu unknown
- 2000-02-17 KR KR1020017010418A patent/KR20010108228A/ko not_active Application Discontinuation
- 2000-02-17 JP JP2000599740A patent/JP2002537288A/ja active Pending
- 2000-02-17 CZ CZ20012973A patent/CZ20012973A3/cs unknown
- 2000-02-17 BR BR0008329-1A patent/BR0008329A/pt not_active IP Right Cessation
- 2000-02-17 EP EP00903881A patent/EP1157009A1/en not_active Withdrawn
- 2000-02-17 WO PCT/GB2000/000570 patent/WO2000049000A1/en not_active Application Discontinuation
- 2000-02-17 AU AU25632/00A patent/AU767332B2/en not_active Ceased
- 2000-02-17 CN CNB00803947XA patent/CN1142916C/zh not_active Expired - Fee Related
-
2001
- 2001-08-07 ZA ZA200106478A patent/ZA200106478B/en unknown
- 2001-08-15 NO NO20013978A patent/NO20013978D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010108228A (ko) | 2001-12-07 |
| EA004745B1 (ru) | 2004-08-26 |
| AU767332B2 (en) | 2003-11-06 |
| ZA200106478B (en) | 2002-02-07 |
| IL144810A0 (en) | 2002-06-30 |
| GB9903671D0 (en) | 1999-04-14 |
| HUP0200057A2 (en) | 2002-08-28 |
| EP1157009A1 (en) | 2001-11-28 |
| AU2563200A (en) | 2000-09-04 |
| MXPA01008294A (es) | 2002-07-02 |
| WO2000049000A1 (en) | 2000-08-24 |
| CN1142916C (zh) | 2004-03-24 |
| PL349838A1 (en) | 2002-09-23 |
| NO20013978L (no) | 2001-08-15 |
| BR0008329A (pt) | 2002-01-29 |
| EA200100783A1 (ru) | 2002-02-28 |
| CZ20012973A3 (cs) | 2002-01-16 |
| CN1341102A (zh) | 2002-03-20 |
| NO20013978D0 (no) | 2001-08-15 |
| JP2002537288A (ja) | 2002-11-05 |
| HUP0200057A3 (en) | 2004-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |