IL144810A0 - Dopamine d1 receptor agonist compounds - Google Patents

Dopamine d1 receptor agonist compounds

Info

Publication number
IL144810A0
IL144810A0 IL14481000A IL14481000A IL144810A0 IL 144810 A0 IL144810 A0 IL 144810A0 IL 14481000 A IL14481000 A IL 14481000A IL 14481000 A IL14481000 A IL 14481000A IL 144810 A0 IL144810 A0 IL 144810A0
Authority
IL
Israel
Prior art keywords
dopamine
receptor agonist
agonist compounds
compounds
receptor
Prior art date
Application number
IL14481000A
Other languages
English (en)
Original Assignee
Cenes Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cenes Ltd filed Critical Cenes Ltd
Publication of IL144810A0 publication Critical patent/IL144810A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
IL14481000A 1999-02-17 2000-02-17 Dopamine d1 receptor agonist compounds IL144810A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9903671.7A GB9903671D0 (en) 1999-02-17 1999-02-17 Dopamine D-1 receptor agonist compounds
PCT/GB2000/000570 WO2000049000A1 (en) 1999-02-17 2000-02-17 Dopamine d1 receptor agonist compounds

Publications (1)

Publication Number Publication Date
IL144810A0 true IL144810A0 (en) 2002-06-30

Family

ID=10847990

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14481000A IL144810A0 (en) 1999-02-17 2000-02-17 Dopamine d1 receptor agonist compounds

Country Status (17)

Country Link
EP (1) EP1157009A1 (es)
JP (1) JP2002537288A (es)
KR (1) KR20010108228A (es)
CN (1) CN1142916C (es)
AU (1) AU767332B2 (es)
BR (1) BR0008329A (es)
CA (1) CA2363695A1 (es)
CZ (1) CZ20012973A3 (es)
EA (1) EA004745B1 (es)
GB (1) GB9903671D0 (es)
HU (1) HUP0200057A3 (es)
IL (1) IL144810A0 (es)
MX (1) MXPA01008294A (es)
NO (1) NO20013978L (es)
PL (1) PL349838A1 (es)
WO (1) WO2000049000A1 (es)
ZA (1) ZA200106478B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130576D0 (en) * 2001-12-20 2002-02-06 Cenes Ltd Dopamine D1 receptor agonist pro-drug compounds & derivatives
BRPI0613403A2 (pt) * 2005-07-15 2009-02-10 Amr Technology Inc tetrahidrobenzodiazepinas aril- e heteroarila-substituÍdas e uso das mesmas para bloquear a recaptaÇço de norepinefrina, dopamina e serotonina
AU2006278514A1 (en) * 2005-08-03 2007-02-15 Mia Levite Killing human lymphoma and leukemia cancer cells and TCR-activated normal human cells by dopamine D1R agonists
CN101684096A (zh) * 2008-09-23 2010-03-31 中国科学院上海药物研究所 一类新型苯并氮杂卓类化合物及其制备方法和用途
CN102276531A (zh) * 2011-05-30 2011-12-14 扬子江药业集团广州海瑞药业有限公司 一种甲磺酸非诺多泮的制备方法
HRP20230546T1 (hr) 2013-06-27 2023-08-04 Pfizer Inc. Heteroaromatski spojevi i njihova upotreba kao dopaminskih d1 liganada

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1561305A (en) * 1975-07-02 1980-02-20 Smithkline Corp Benzazepine derivatives and pharmeceutical compositions containing them
US4111957A (en) * 1977-02-02 1978-09-05 Smithkline Corporation Substituted 1-thienyl and furyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds
US4265889A (en) * 1978-05-05 1981-05-05 Smithkline Corporation 6-Lower alkyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4707483A (en) * 1985-12-20 1987-11-17 Smithkline Beckman Corporation 1-phenyl-3-benzazepines and their use for treating gastrointestinal motility disorders
US4861771A (en) * 1989-01-27 1989-08-29 Smithkline Beckman Corporation Carbamates of 6-chloro-7,8-dihydroxy-1-(4'-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine as prodrugs

Also Published As

Publication number Publication date
CN1341102A (zh) 2002-03-20
CN1142916C (zh) 2004-03-24
ZA200106478B (en) 2002-02-07
MXPA01008294A (es) 2002-07-02
HUP0200057A2 (en) 2002-08-28
JP2002537288A (ja) 2002-11-05
NO20013978D0 (no) 2001-08-15
AU2563200A (en) 2000-09-04
CZ20012973A3 (cs) 2002-01-16
BR0008329A (pt) 2002-01-29
WO2000049000A1 (en) 2000-08-24
EP1157009A1 (en) 2001-11-28
HUP0200057A3 (en) 2004-03-29
GB9903671D0 (en) 1999-04-14
CA2363695A1 (en) 2000-08-24
PL349838A1 (en) 2002-09-23
AU767332B2 (en) 2003-11-06
KR20010108228A (ko) 2001-12-07
EA004745B1 (ru) 2004-08-26
EA200100783A1 (ru) 2002-02-28
NO20013978L (no) 2001-08-15

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