HUP0200057A3 - Dopamine d1 receptor agonist compounds, pharmaceutical compositions containing them and their use - Google Patents

Dopamine d1 receptor agonist compounds, pharmaceutical compositions containing them and their use

Info

Publication number
HUP0200057A3
HUP0200057A3 HU0200057A HUP0200057A HUP0200057A3 HU P0200057 A3 HUP0200057 A3 HU P0200057A3 HU 0200057 A HU0200057 A HU 0200057A HU P0200057 A HUP0200057 A HU P0200057A HU P0200057 A3 HUP0200057 A3 HU P0200057A3
Authority
HU
Hungary
Prior art keywords
dopamine
pharmaceutical compositions
compositions containing
receptor agonist
agonist compounds
Prior art date
Application number
HU0200057A
Other languages
English (en)
Original Assignee
Shire Pharmaceutical Dev Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Pharmaceutical Dev Ltd filed Critical Shire Pharmaceutical Dev Ltd
Publication of HUP0200057A2 publication Critical patent/HUP0200057A2/hu
Publication of HUP0200057A3 publication Critical patent/HUP0200057A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
HU0200057A 1999-02-17 2000-02-17 Dopamine d1 receptor agonist compounds, pharmaceutical compositions containing them and their use HUP0200057A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9903671.7A GB9903671D0 (en) 1999-02-17 1999-02-17 Dopamine D-1 receptor agonist compounds

Publications (2)

Publication Number Publication Date
HUP0200057A2 HUP0200057A2 (en) 2002-08-28
HUP0200057A3 true HUP0200057A3 (en) 2004-03-29

Family

ID=10847990

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0200057A HUP0200057A3 (en) 1999-02-17 2000-02-17 Dopamine d1 receptor agonist compounds, pharmaceutical compositions containing them and their use

Country Status (17)

Country Link
EP (1) EP1157009A1 (hu)
JP (1) JP2002537288A (hu)
KR (1) KR20010108228A (hu)
CN (1) CN1142916C (hu)
AU (1) AU767332B2 (hu)
BR (1) BR0008329A (hu)
CA (1) CA2363695A1 (hu)
CZ (1) CZ20012973A3 (hu)
EA (1) EA004745B1 (hu)
GB (1) GB9903671D0 (hu)
HU (1) HUP0200057A3 (hu)
IL (1) IL144810A0 (hu)
MX (1) MXPA01008294A (hu)
NO (1) NO20013978L (hu)
PL (1) PL349838A1 (hu)
WO (1) WO2000049000A1 (hu)
ZA (1) ZA200106478B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130576D0 (en) * 2001-12-20 2002-02-06 Cenes Ltd Dopamine D1 receptor agonist pro-drug compounds & derivatives
EP1904069B1 (en) 2005-07-15 2018-06-13 Albany Molecular Research, Inc. Aryl-and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
CN101296943A (zh) * 2005-08-03 2008-10-29 米亚·利维特 通过多巴胺d1r激动剂杀伤人类淋巴瘤和白血病癌细胞和tcr活化的人类正常细胞
CN101684096A (zh) * 2008-09-23 2010-03-31 中国科学院上海药物研究所 一类新型苯并氮杂卓类化合物及其制备方法和用途
CN102276531A (zh) * 2011-05-30 2011-12-14 扬子江药业集团广州海瑞药业有限公司 一种甲磺酸非诺多泮的制备方法
HUE043705T2 (hu) * 2013-06-27 2019-09-30 Pfizer Heteroaromás vegyületek és dopamin D1 ligandumként történõ alkalmazásuk

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1561305A (en) * 1975-07-02 1980-02-20 Smithkline Corp Benzazepine derivatives and pharmeceutical compositions containing them
US4111957A (en) * 1977-02-02 1978-09-05 Smithkline Corporation Substituted 1-thienyl and furyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds
US4265889A (en) * 1978-05-05 1981-05-05 Smithkline Corporation 6-Lower alkyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4707483A (en) * 1985-12-20 1987-11-17 Smithkline Beckman Corporation 1-phenyl-3-benzazepines and their use for treating gastrointestinal motility disorders
US4861771A (en) * 1989-01-27 1989-08-29 Smithkline Beckman Corporation Carbamates of 6-chloro-7,8-dihydroxy-1-(4'-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine as prodrugs

Also Published As

Publication number Publication date
IL144810A0 (en) 2002-06-30
CA2363695A1 (en) 2000-08-24
NO20013978D0 (no) 2001-08-15
AU2563200A (en) 2000-09-04
GB9903671D0 (en) 1999-04-14
JP2002537288A (ja) 2002-11-05
ZA200106478B (en) 2002-02-07
PL349838A1 (en) 2002-09-23
BR0008329A (pt) 2002-01-29
EP1157009A1 (en) 2001-11-28
MXPA01008294A (es) 2002-07-02
EA200100783A1 (ru) 2002-02-28
NO20013978L (no) 2001-08-15
KR20010108228A (ko) 2001-12-07
CZ20012973A3 (cs) 2002-01-16
CN1142916C (zh) 2004-03-24
EA004745B1 (ru) 2004-08-26
WO2000049000A1 (en) 2000-08-24
CN1341102A (zh) 2002-03-20
HUP0200057A2 (en) 2002-08-28
AU767332B2 (en) 2003-11-06

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