CA2337270C - Procede de preparation du 4-(3-pyridinyl)-1h-imidazole et les intermediaires mis en oeuvre - Google Patents

Procede de preparation du 4-(3-pyridinyl)-1h-imidazole et les intermediaires mis en oeuvre Download PDF

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Publication number
CA2337270C
CA2337270C CA002337270A CA2337270A CA2337270C CA 2337270 C CA2337270 C CA 2337270C CA 002337270 A CA002337270 A CA 002337270A CA 2337270 A CA2337270 A CA 2337270A CA 2337270 C CA2337270 C CA 2337270C
Authority
CA
Canada
Prior art keywords
formula
pyridinyl
action
compound
subjected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002337270A
Other languages
English (en)
French (fr)
Other versions
CA2337270A1 (fr
Inventor
Raphael Bouchet
Jacques Lagouardat
Jacques Scholl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of CA2337270A1 publication Critical patent/CA2337270A1/fr
Application granted granted Critical
Publication of CA2337270C publication Critical patent/CA2337270C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/51—Acetal radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002337270A 1998-07-09 1999-07-08 Procede de preparation du 4-(3-pyridinyl)-1h-imidazole et les intermediaires mis en oeuvre Expired - Fee Related CA2337270C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9808796A FR2780973B1 (fr) 1998-07-09 1998-07-09 Procede de preparation du 4-(3-pyridinyl)-1h-imidazole, et les intermediaires mis en oeuvre
FR98/08796 1998-07-09
PCT/FR1999/001649 WO2000002875A1 (fr) 1998-07-09 1999-07-08 Procede de preparation du 4-(3-pyridinyl)-1h-imidazole et les intermediaires mis en oeuvre

Publications (2)

Publication Number Publication Date
CA2337270A1 CA2337270A1 (fr) 2000-01-20
CA2337270C true CA2337270C (fr) 2009-11-24

Family

ID=9528458

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002337270A Expired - Fee Related CA2337270C (fr) 1998-07-09 1999-07-08 Procede de preparation du 4-(3-pyridinyl)-1h-imidazole et les intermediaires mis en oeuvre

Country Status (19)

Country Link
US (1) US6353108B1 (sl)
EP (1) EP1095035B1 (sl)
JP (1) JP4583600B2 (sl)
CN (1) CN1152872C (sl)
AR (1) AR016733A1 (sl)
AT (1) ATE461187T1 (sl)
AU (1) AU4625199A (sl)
CA (1) CA2337270C (sl)
CY (1) CY1110121T1 (sl)
DE (1) DE69942150D1 (sl)
DK (1) DK1095035T3 (sl)
ES (1) ES2343155T3 (sl)
FR (1) FR2780973B1 (sl)
HU (1) HU229690B1 (sl)
MX (1) MXPA01000187A (sl)
PT (1) PT1095035E (sl)
SI (1) SI1095035T1 (sl)
TW (1) TW496867B (sl)
WO (1) WO2000002875A1 (sl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6649768B1 (en) 2002-12-04 2003-11-18 Sumika Fine Chemicals Co., Ltd. Production methods of imidazole compound and salt thereof and intermediates therefor
DE10305391A1 (de) * 2003-02-11 2004-08-19 Aventis Pharma Deutschland Gmbh Verfahren zur Herstellung von Pyridin-substituierten Aminoketal-Derivaten
US20080188527A1 (en) * 2003-12-23 2008-08-07 Cashman John R Synthetic Compounds and Derivatives as Modulators of Smoking or Nicotine Ingestion and Lung Cancer
PE20070427A1 (es) * 2005-08-30 2007-04-21 Novartis Ag Compuestos derivados de benzimidazoles sustituidos como inhibidores de tirosina quinasas
JP2006316049A (ja) * 2006-04-11 2006-11-24 Tanabe Seiyaku Co Ltd ２，２−ジアルコキシエチルアミン化合物およびその製造方法
WO2012052412A1 (de) 2010-10-22 2012-04-26 Bayer Cropscience Ag Neue heterocylische verbindungen als schädlingsbekämpfungsmittel
CA2943882A1 (en) 2014-05-22 2015-11-26 F. Hoffmann-La Roche Ag Indolin-2-one and 1,3-dihydro-pyrrolo[3,2-c]pyridin-2-one derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4302464A (en) * 1980-10-16 1981-11-24 Pfizer Inc. Imidazolylpyridine therapeutic agents
JPS57136573A (en) * 1981-02-17 1982-08-23 Sagami Chem Res Center Preparation of imidazole compound
JPH02145572A (ja) * 1988-11-21 1990-06-05 Zhongguo Yixuekexueyuan Yaowo Yanjiusuo Ｎ−置換アミド類
JPH0324009A (ja) * 1989-06-22 1991-02-01 Taisho Pharmaceut Co Ltd 肝疾患治療剤

Also Published As

Publication number Publication date
CN1152872C (zh) 2004-06-09
HU229690B1 (en) 2014-04-28
CY1110121T1 (el) 2015-01-14
EP1095035A1 (fr) 2001-05-02
PT1095035E (pt) 2010-06-08
DE69942150D1 (de) 2010-04-29
FR2780973A1 (fr) 2000-01-14
US6353108B1 (en) 2002-03-05
MXPA01000187A (es) 2002-10-17
TW496867B (en) 2002-08-01
ATE461187T1 (de) 2010-04-15
AR016733A1 (es) 2001-07-25
WO2000002875A1 (fr) 2000-01-20
CN1308628A (zh) 2001-08-15
HUP0104797A2 (hu) 2002-04-29
ES2343155T3 (es) 2010-07-23
JP2002520325A (ja) 2002-07-09
JP4583600B2 (ja) 2010-11-17
FR2780973B1 (fr) 2001-10-05
CA2337270A1 (fr) 2000-01-20
SI1095035T1 (sl) 2010-07-30
HUP0104797A3 (en) 2003-01-28
DK1095035T3 (da) 2010-07-19
EP1095035B1 (fr) 2010-03-17
AU4625199A (en) 2000-02-01

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Effective date: 20160708